Clinical trials: Heart Disease, Coronary
Cardiopathy, Surgery
Bilevel Positive Airway Pressure in Cardiac Surgery
The purpose of this study was to determine the effects of Bilevel Positive Airway Pressure (BiPAP) on variables clinics, cardiorespiratory and physical functional in patients undergoing cardiac surgery at the University Hospital…
- Trial name
- NCT02600182
- Testing
- Bilevel Positive Airway Pressure
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Prof. Dr. Antônio Marcos Vargas da Silva
Alcohol Use Disorder, Post Traumatic Stress Disorder
Stress, Emotion Regulation, and Alcohol in Women Veterans
The purpose of the study "Stress, Emotion Regulation, and Alcohol in Women Veterans" is to learn about the effects of negative emotion and stress on behavior (including alcohol use) among women Veterans, including women with and…
- Trial name
- SERA (NCT04393623)
- Testing
- Cognitive Reappraisal, Psychoeducation
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Mitral Valve Prolapse, Mitral Regurgitation
The Role of cardIac magNeTic rEsonance in surGical Decision Making in Patients With Severe pRimAry miTral rEgurgitation
Mitral regurgitation (MR) is the second most frequent valvular heart disease and the second most frequent indication for valve surgery in Europe.
- Trial name
- INTEGRATE (NCT07366723)
- Testing
- mitral valve surgery, Clinical Follow up
- Where
- Italy
- Volunteers
- 260 people
- Sponsor
- Centro Cardiologico Monzino
Myocardial Infarction, Influenza
The Role of Influenza as a Trigger for Acute Myocardial Infarction: a CALIBER Study
The purpose of this study is to examine the incidence of acute myocardial infarction (MI) occurring after an influenza-like illness using linked primary care and disease registry databases.
- Trial name
- NCT01106196
- Where
- 2 sites in United Kingdom
- Volunteers
- 11,208 people
- Sponsor
- University College, London
Atrial Fibrillation
Manual Compared to Magnetic Navigation in Ablation for Atrial Fibrillation
The purpose of this study is to compare manual and magnetic navigation in ablation for atrial fibrillation.
- Trial name
- NCT01407588
- Testing
- Magnetic navigation, Ablation performed with manual navigation
- Where
- Norway
- Volunteers
- 51 people
- Sponsor
- Norwegian University of Science and Technology
Coronary Artery Disease
HsTnT in Stable Coronary Artery Disease
Coronary artery disease (CAD) is one of the leading causes of morbidity and mortality worldwide. Life threatening manifestations such as acute myocardial infarction (AMI) and sudden cardiac death are the most important causes of…
- Trial name
- NCT01954303
- Testing
- Progress of CHD
- Volunteers
- 965 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Heart Failure, Congestive, Ventricular Fibrillation
Safety and Effectiveness of Cardiac Resynchronization Therapy With Defibrillation
The purpose of this study was to determine if cardiac resynchronization therapy when combined with defibrillation is safe and effective in the treatment of symptomatic heart failure.
- Conditions
- Heart Failure, Congestive, Ventricular Fibrillation, Tachycardia, Ventricular
- Trial name
- NCT00387803
- Testing
- Cardiac Resynchronization Therapy with Defibrillation
- Where
- United States
- Volunteers
- 581 people
- Sponsor
- Boston Scientific Corporation
Diabetes Mellitus, Type 2, Heart Failure
Randomised Trial of Health Coaching in Secondary Prevention of Diabetes and Heart Disease
A randomised trial with individual patients as units of observation will be carried out. Health coaching is used to modify health behaviour and thus improve disease control and health status, as well as use of health care…
- Conditions
- Diabetes Mellitus, Type 2, Heart Failure, Coronary Disease
- Trial name
- TerVa (NCT00552903)
- Testing
- Health coaching
- Where
- Finland
- Volunteers
- 1,500 people
- Sponsor
- Paijat-Hame Hospital District
Atrial Functional Mitral Regurgitation, Heart Failure
Atrial Functional Mitral Regurgitation Response In Mitral Loop Cerclage Annuloplasty (AFRICA Study)
To evaluate second stage safety and feasibility of Mitral Loop Cerclage(MLC) Annuloplasty with CSTV for repair of functional mitral regurgitation.
- Trial name
- AFRICA (NCT03453853)
- Testing
- Mitral Loop Cerclage Annuloplasty
- Where
- 7 sites in South Korea
- Volunteers
- 1 people
- Sponsor
- Tau-MEDICAL Co., Ltd.
Coronary Artery Disease, Diabetes Mellitus
Mitochondrial Bioenergetics and Role in Cellular Damage in Ischemic Myocardium
Cardiac ischemia is a common pathological condition, known to elicit multiple pathological processes at the cellular level. One of the most affected is thought to be cellular metabolism, key for the adequate cardiac function.
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Mitochondrial Metabolism Disorders
- Trial name
- NCT03179137
- Testing
- Standard therapy
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- University of Split, School of Medicine
Coronary Artery Disease, Coronary Artery Calcification
Coronary Artery Calcification Assessed on PET Scanner (PET : Positron Emission Tomography)
Calcification artery calcium (CAC) scoring is a valuable tool for determining the risk of major adverse cardiac events. It was found that CAC can be quantitatively assessed, by manual scoring or using deep-learning, on low-dose…
- Trial name
- CALCOTEP (NCT06379295)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Heart Failure, Congestive Heart Failure
Personalized Voice Activated Wellness Assistants for Patients With Heart Failure
The Alexa+ Study will compare the use of the Amazon Echo Dot with Alexa voice technology in patients with chronic heart failure to those receiving standard of care heart failure management on changes in health and…
- Trial name
- NCT03707275
- Testing
- Alexa+, Standard of Care Arm
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medstar Health Research Institute
Single-ventricle
Fibrosis and the Fontan
The purpose of this study is to non-invasively characterize the fibrotic consequences of single ventricle physiology, its possible solution and effect on lymphatics.
- Trial name
- NCT04901975
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Children's Hospital of Philadelphia
Heart Failure, Coronary Artery Disease
Maximal Leg Press Strength Training Study for Coronary Artery Disease Patients
Maximal strength training has been shown to increase muscular strength, muscular volume and work economy. An 8 week maximal leg press training regime will be conducted on cardiac heart failure patients to evaluate whether they…
- Trial name
- NCT00184457
- Testing
- Strength training intervention
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Cardiac Disease, Cardiopulmonary Disease
World Trade Center (WTC) RENAL
Environmental toxins exert damaging health effects in workers. Thousands of responders who worked or volunteered on the World Trade Center (WTC) rescue and recovery effort following the September 11, 2001 attacks suffer from…
- Conditions
- Cardiac Disease, Cardiopulmonary Disease, Renal Disease, Cardiovascular Disease
- Trial name
- NCT02246101
- Where
- United States
- Volunteers
- 406 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiac Arrest, Simulation of Physical Illness
CPR Surface Choice on Chest Compression Quality
The objective of our randomized simulation study on mannequins with a population of Basic Life Support students is to compare the quality of chest compressions, taking depth as the main variable, in two simulated scenarios of…
- Trial name
- NCT06406101
- Testing
- Floor, Bed
- Where
- Spain
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Non-ST-elevation Myocardial Infarction
Thrombus Aspiration in ThrOmbus Containing culpRiT Lesions in Non-ST-Elevation Myocardial Infarction (TATORT-NSTEMI)
Whereas thrombus aspiration in patients with ST-elevation myocardial infarction (STEMI) is recommended by current guidelines, there are insufficient data to unequivocally support thrombectomy in patients with non-STEMI (NSTEMI).
- Trial name
- NCT01612312
- Testing
- Thrombectomy, Standard percutaneous coronary intervention
- Where
- 7 sites in Germany
- Volunteers
- 400 people
- Sponsor
- University of Leipzig
DCM - Dilated Cardiomyopathy
Observational Study for Patients With Dilated Cardiomyopathy
Observational study on patients with dilated cardiomyopathy aims to investigate the correlation between cardiac fibrosis, as indicated by cardiac magnetic resonance, and the prognosis of patients with dilated cardiomyopathy, and…
- Trial name
- NCT04837612
- Testing
- No intervention nor exposure
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Guangdong Provincial People's Hospital
Congestive Heart Failure
Autonomic Regulation Therapy in Heart Failure With Preserved Ejection Fraction
The ANTHEM-HFpEF Study is designed to demonstrate the safety and efficacy of vagus nerve stimulation (VNS) with the Cyberonics VNS Therapy System for the treatment of subjects with symptomatic heart failure with preserved and…
- Trial name
- NCT03163030
- Testing
- Vagus Nerve Stimulation (VNS)
- Where
- India
- Volunteers
- 52 people
- Sponsor
- Cyberonics, Inc.
Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy
The purpose of this study is to determine the clinical benefit and characterize the safety profile of tabelecleucel for the treatment of Epstein-Barr virus-associated post-transplant lymphoproliferative disease (EBV+ PTLD) in the…
- Conditions
- Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant
- Trial name
- ALLELE (NCT03394365)
- Testing
- tabelecleucel
- Where
- 71 sites in United States, Australia and 7 more
- Volunteers
- 115 people
- Sponsor
- Pierre Fabre Medicament
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