Clinical trials: Heart Failure, Unspecified
Heart Failure, Telemonitoring
EXPLORATORY STUDY OF THE MYHEARTSENTINEL SYSTEM, A CARDIAMETRICS MEDICAL DEVICE
Background: Chronic heart failure represents a major public health challenge, affecting approximately 64 million people worldwide and generating high costs in terms of mortality, frequent hospitalizations, and medical expenses.
- Conditions
- Heart Failure, Telemonitoring, Right Heart Catheterisation
- Trial name
- ASEMC-DR (NCT07345533)
- Testing
- MYHEARTSENTINEL SYSTEM cutaneous DEVICE
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Caen
End-stage Heart Failure
Mechanical Circulatory Support Korea Post Market Surveillance Study (PMS)
Medtronic is sponsoring this Mechanical Circulatory Support (MCS) Korea Post-Market Surveillance (PMS) to evaluate the safety and performance of the HeartWare Ventricular Assist Device System (HVAD® System) when used in routine…
- Trial name
- NCT04543747
- Testing
- HeartWare Ventricular Assist Device
- Where
- 2 sites in South Korea
- Volunteers
- 77 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Sleep Apnea, Central, Sleep Disordered Breathing
Respicardia, Inc. Pivotal Trial of the remedē System
The primary purpose of this prospective, multicenter, randomized trial is to evaluate the safety and effectiveness of therapy delivered by the remedē® system in subjects with moderate to severe central sleep apnea and optimal…
- Conditions
- Sleep Apnea, Central, Sleep Disordered Breathing, Heart Failure
- Trial name
- NCT01816776
- Testing
- Treatment Group (transvenous stimulation of the phrenic nerve), Control Group (Optimal Medical Therapy)
- Where
- 30 sites in United States, Germany and 1 more
- Volunteers
- 151 people
- Sponsor
- Respicardia, Inc.
Cardiac Failure, Graft Rejection
Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs
This study aims to discover circulating microRNAs (associated with drug doses and levels) that can be used to characterize the overall immune state in pediatric heart transplant patients and predict patients that will go on to…
- Trial name
- OPTIMA (NCT06532890)
- Where
- 7 sites in United States
- Volunteers
- 150 people
- Sponsor
- Northwestern University
Heart Failure, Ventricular Dysfunction
Effects of Nesiritide in Pediatric Patients With Heart Failure
Children with severe heart failure need immediate appropriate care. New and better drugs are constantly being developed. As these drugs are approved for adult use, they are used off-label for children.
- Conditions
- Heart Failure, Ventricular Dysfunction, Heart Decompensation
- Trial name
- NCT00166010
- Testing
- Nesiritide
- Sponsor
- Emory University
Cardiac Failure, Respiratory Failure
A Post Market Surveillance Study of the Hemovent Extracorporeal Cardiopulmonary Support System:The MOBYBOX Trial
The purpose of this study is to evaluate prospectively the safety and performance of the MOBYBOX System in the veno-arterial configuration in patients with cardiorespiratory failure or in the veno-venous configuration in patients…
- Conditions
- Cardiac Failure, Respiratory Failure, Cardio-Respiratory Failure, Imminent Cardiorespiratory or Respiratory Failure
- Trial name
- NCT04183660
- Testing
- MOBYBOX System
- Where
- 4 sites in Germany
- Volunteers
- 60 people
- Sponsor
- Hemovent GmbH
Heart Failure, Congestive, Cardiomyopathy
Impact of Nesiritide Infusion for Decompensated Heart Failure in the Emergency Department
The purpose of this study is to determine if an 8hr infusion of nesiritide in the emergency department in the Acutely decompensated heart failure patients will decrease 30 day recidivism.
- Trial name
- NCT00559338
- Testing
- recombinant B-type, natriuretic peptide
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Texas Southwestern Medical Center
Cardiovascular Diseases
Identifying High- and Low-Risk Heart Failure Patients in the Emergency Department (The Stratify Study)
People with heart failure (HF) symptoms who are seen in the emergency department (ED) are often admitted to the hospital even though it may not be necessary.
- Trial name
- Stratify (NCT00508638)
- Where
- United States
- Volunteers
- 1,033 people
- Sponsor
- Vanderbilt University
Heart Diseases
Effects of Recorded Music in Heart Failure Patients
Aims. To describe a new conceptual framework and to test the effectiveness of a recorded music listening protocol on symptom burden and quality of life in heart failure patients.
- Trial name
- EMSC (NCT02394938)
- Testing
- MUSIC
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Usl di Bologna
Percutaneous Coronary Intervention, Heart Failure
REgiStry-based Cardiovascular qUality improvEment Research
The goal of this registry-based observational study is to establish a comprehensive management plan, which focus on medical therapy, cardiac rehabilitation and active post-market surveillance of medical devices, in patients with…
- Conditions
- Percutaneous Coronary Intervention, Heart Failure, Cardiometabolic Syndrome, Structural Heart Abnormality
- Trial name
- RESCUER (NCT06137885)
- Testing
- Cardiac rehabilitation, Active post-market surveillance of devices, Multi-omics approach to precision medicine
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Peking University Third Hospital
Acute Heart Failure, Emergencies
Risk Stratification Using MEESSI-AHF Scale in ED and Impact on AHF Outcomes
Evaluate the impact the application of the MESSI-AHF scale (a risk stratification scale specifically derived and validated in patients diagnosed with acute heart failure, AHF) in decision making (admission vs.
- Trial name
- MEESSI (NCT05919225)
- Testing
- Risk stratification before decision-making about patient hospitalization or discharge
- Where
- 19 sites in Spain
- Volunteers
- 3,200 people
- Sponsor
- Hospital Clinic of Barcelona
Heart Failure, Mild Cognitive Impairment
Impact of Yoga on Cognitive Function
Mild cognitive impairment is highly prevalent in patients with heart failure and results in poor well-being and quality of life.
- Trial name
- NCT06434168
- Testing
- Yoga intervention, Control condition
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Auburn University
Heart Failure
The Need for FibEr Addition in SympTomatic Heart Failure
FEAST-HF is a single-centre clinical trial in ambulatory patients with chronic HF to evaluate whether dietary supplementation with acacia gum reduces HF-related biomarkers NT-proBNP and ST2 and how the gut microbiome responds to…
- Trial name
- FEAST-HF (NCT03409926)
- Testing
- Acacia Gum
- Where
- 3 sites in Canada
- Volunteers
- 51 people
- Sponsor
- University of Alberta
Heart Failure with Preserved Ejection Fraction
HFPEF-project: Heart Failure Phenotyping - Exploring the Fingerprints
With an ageing population, the number of patients with heart failure with preserved ejection fraction (HFpEF) or diastolic heart failure is increasing rapidly.
- Trial name
- NCT06465043
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- University of Helsinki
Sarcopenia, Chronic Heart Failure
Assessments of Sarcopenia Prevalence in Chronic Heart Failure Patients and in Subjects Before TAVI
The main objective was to assess the prevalence of sarcopenia in chronic heart failure patients and in patients before the trans aortic valvular implantation.
- Trial name
- PRESAR-HF (NCT03153774)
- Testing
- Assessment of sarcopenia prevalence
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Failure
Crestor Versus Placebo in Subjects With Heart Failure
The purpose of the study is to investigate if rosuvastatin, added on top of all other medicines prescribed to subjects with symptomatic systolic heart failure, reduces the combined endpoint of cardiovascular death or non-fatal…
- Trial name
- NCT00206310
- Testing
- CRESTOR
- Where
- 375 sites in Belgium, Bulgaria and 19 more
- Volunteers
- 5,013 people
- Sponsor
- AstraZeneca
Heart Failure
Danish Pragmatic Randomized Trial to Evaluate the Effect of HeartLogic-Guided Management on Heart Failure Outcomes
The purpose of the study is to assess the impact of HeartLogic-guided management on clinical outcomes among patients implanted with an eligible cardiac device.
- Trial name
- DANLOGIC-HF (NCT06099158)
- Testing
- HeartLogic
- Where
- 5 sites in Denmark
- Volunteers
- 1,428 people
- Sponsor
- Tor Biering-Sørensen
Chronic Heart Failure, Acute Decompensated Heart Failure
Therapy Adjustment and IndividuaLized Response With Biomarker Observation in ReaL-world Heart Failure
The goal of TAILOR-HF is to integrate clinical data, laboratory parameters, treatment patterns, and circulating biomarkers to identify factors that predict individual response to pharmacological treatment in patients with heart…
- Trial name
- TAILOR-HF (NCT07647848)
- Volunteers
- 600 people
- Sponsor
- Maastricht University Medical Center
Heart Failure
Premature Fatigue in Veterans With Heart Failure: Neuronal Influences
A hallmark of patients with heart failure (HF) is premature fatigue which impairs their quality of life and depicts a major source of morbidity.
- Trial name
- NCT02209610
- Testing
- Electrical and Magnetic Nerve Stimulators, Intrathecal Fentanyl
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Heart Failure
The Effect of Nursing Care Decision Support System Designed for Fluid Volume Excess of Patients With Heart Failure on Clinical Outcomes of Patients and Home Self-Care Outcomes
This study aims to evaluate the effects of a nursing care decision support system designed to reduce fluid overload in patients with heart failure.
- Trial name
- HF-DSS-Nursing (NCT07067047)
- Testing
- Nursing Decision Support System
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Leyla Biçen
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