Clinical trials: Heart Failure, Unspecified
Acute Heart Failure
Loop Diuretic Therapy in Acutely Decompensated Heart Failure
DiurHF is a prospective, multicenter, observational, study that compares continuous with intermittent infusion of furosemide in patients admitted with a diagnosis of ADHF.
- Trial name
- DIUR-AHF (NCT02638142)
- Testing
- Continuous Furosemide Infusion, Intermittent Furosemide Infusion
- Where
- 4 sites in Italy
- Volunteers
- 370 people
- Sponsor
- University of Siena
Breast Cancer, Heart Failure
Carvedilol Effect in Preventing Chemotherapy - Induced Cardiotoxicity
The purpose of this study is to evaluate if carvedilol can prevent the cardiotoxicity after chemotherapy in breast cancer.
- Conditions
- Breast Cancer, Heart Failure, Cardiotoxicity
- Trial name
- Ceccy (NCT01724450)
- Testing
- Carvedilol
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Ventricular Tachycardia
Exercise Training in ICD Recipients; Effect on Therapy Delivered, Depression and Anxiety
Interventional study in patients with ICD. Controlled, open intervention with exercise training. Assessment of changes in physiological and psychological parameters.
- Trial name
- ETHIC (NCT01038960)
- Testing
- Exercise training
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Helse Stavanger HF
Heart Failure, Iron-deficiency
Beneficial Effects of Vitamin D Combined With Oral Iron Supplementation in Patients With Chronic Heart Failure and Iron Deficiency
The goal of this randomized, controlled, open-label, interventional study is to evaluate whether, in patients with heart failure (HF) and iron deficiency (ID), the administration of vitamin D in combination with sucrosomial iron…
- Conditions
- Heart Failure, Iron-deficiency, Heart Failure, Systolic, Heart Failure NYHA Class II
- Trial name
- VICTORID-HF (NCT05702970)
- Testing
- Sucrosomial iron, Vitamin D, Ferric Carboxymaltose 50 MG/ML
- Volunteers
- 258 people
- Sponsor
- University of Padova
Heart Failure with Preserved Ejection Fraction
Study on Heart Failure with Preserved Ejection Fraction with Qishen Granules
With the cardiopulmonary exercise testing as the primary outcome, the study aims to evaluate the efficacy of Qishen Granules on cardiac function, quality of life and biomarker level of patients with heart failure with preserved…
- Trial name
- NCT06377761
- Testing
- Qishen Granules
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Myeloma, Long COVID
Understanding Patterns of Fatigue in Health and Disease
Fatigue is a common symptom and can be the most distressing symptom of a range of medical conditions. This Ecological Momentary Assessment study will investigate lived experiences of fatigue in detail in individuals with myeloma…
- Conditions
- Myeloma, Long COVID, Heart Failure
- Trial name
- FATIGUE (NCT05622669)
- Testing
- Observational
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Heart Failure, Sleep Apnea Syndromes
Heart Failure and Sleep Apnea: Exercise Training and Continuous Positive Airway Pressure
Introduction. Heart failure is the result of primary ventricular dysfunction followed by neurohormorais changes, distribution of cardiac output, peripheral circulation, the skeletal and respiratory muscles, which determine their…
- Trial name
- CPAP (NCT01538069)
- Testing
- Exercise training, CPAP group, Exercise and CPAP group
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Myocardial Infarct, Remodeling, Left Ventricle
Heart Attack Blood Oxygen Therapy Trial
'Heart attack', known as acute ST-segment elevation myocardial infarction, is a leading cause of heart failure and death. A lack of blood and oxygen damages the heart muscle potentially causing heart failure and premature death.
- Trial name
- SSO2 Radial MI (NCT06662890)
- Testing
- Supersaturated oxygen
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- NHS National Waiting Times Centre Board
Wearable Device, Cardiovascular Disease
HEARTS in Sync + CardioWatch 287-2
The goal of this interventional study is to evaluate the implementation, usability, and clinical outcomes of a wearable medical-grade device in a virtual Cardiac Rehabilitation (CR) program, titled HEARTS in Sync.
- Conditions
- Wearable Device, Cardiovascular Disease, ASCVD Management, CHF - Congestive Heart Failure
- Trial name
- NCT07322510
- Testing
- Remote Patient Monitoring with Corsano CardioWatch 287-2
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Nova Scotia Health Authority
Pulmonary Hypertension, Heart Failure
Study for Evaluation of Safety and Efficacy of PADN to Treat Combined Post- and Pre- Capillary Pulmonary Hypertension Associated With Chronic Heart Failure（PADN-CpcPH-PILOT）
The goal of this pilot study is to evaluate the safety and efficacy of pulmonary artery denervation (PADN) in Combined Post- and Pre- Capillary Pulmonary Hypertension Associated with Chronic Heart Failure.
- Trial name
- NCT05996562
- Testing
- Pulmonary Artery Denervation
- Where
- 7 sites in Georgia, Italy and 3 more
- Volunteers
- 30 people
- Sponsor
- Pulnovo Medical (Wuxi) Co., Ltd.
Heart Failure
Evaluating Teach Back as a Method for Improving Self-Care Behaviours in Heart Failure Patients
Patient education using Teach Back has the potential to increase self-care behaviour in heart failure (HF) patients and reduce adverse clinical outcomes.
- Trial name
- NCT01311583
- Testing
- Teach Back method of patient discharge teaching
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Unity Health Toronto
Acute Heart Failure
Metabolic Modulation as Treatment in Acute Heart Failure
The primary objective of this study is to evaluate whether metabolic modulation improves hemodynamics and outcome in acute heart failure
- Trial name
- MEMO (NCT00449423)
- Testing
- acipimox
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Aarhus
Heart Failure
A Supportive Care Programme for People With Heart Failure
Efficient health care systems for the management of chronic diseases in the community may improve clinical outcomes and simultaneously encourage patients to remain healthy.
- Trial name
- SupportHeart (NCT04415723)
- Testing
- supportive care management programme
- Where
- Cyprus
- Volunteers
- 200 people
- Sponsor
- Cyprus University of Technology
Frailty Syndrome, Heart Failure
Study to Explore the Safety and Feasibility of Allogeneic Young Plasma Infusion in Older Adults
Evaluate the feasibility of administering plasma (PF24) acquired from donors of a young chronological age intravenously to older adults at WFBMC while also exploring its effects on age-related functional decline
- Trial name
- NCT04241159
- Testing
- Allogeneic Young Plasma
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Heart Failure
Heart Failure Food Intervention Trial: Impact of a Guideline-based Nutrition Digital Tool in Heart Failure Patient Clinical Outcomes
Measuring the impact of a guideline-based nutrition digital tool in heart failure patients
- Trial name
- HF-FIT (NCT06999369)
- Testing
- MedChef App, MedChefs and Instacart food voucher
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Sutter Health
Chronic Heart Failure, Metabolic Syndrome
Follow-up of GANI_MED Cardio Cohorts
Follow-up of two hospital-based patient cohorts (heart failure, metabolic comorbidities in CVD), recruited at baseline by the GANI_MED-project (Greifswald Approach to Individualized Medicine).
- Trial name
- GANIFU-Card (NCT02970214)
- Testing
- no intervention, only observational
- Where
- Germany
- Volunteers
- 1,200 people
- Sponsor
- University Medicine Greifswald
Heart Failure New York Heart Association Class III, Heart Failure New York Heart Association Class IV
Levosimendan In Ambulatory Heart Failure Patients
The objective of the study is to determine the efficacy of repeated infusions of levosimendan in the group of outpatients with advanced systolic heart failure (HF).
- Conditions
- Heart Failure New York Heart Association Class III, Heart Failure New York Heart Association Class IV, Heart Failure, Systolic, Heart Failure With Reduced Ejection Fraction
- Trial name
- LEIA-HF (NCT04705337)
- Testing
- Levosimendan
- Where
- 14 sites in Poland
- Volunteers
- 70 people
- Sponsor
- Medical University of Bialystok
Heart Failure
Screening Evaluation of the Evolution of New Heart Failure (SCREEN-HF)
The investigators are hoping to identify early heart failure in patients who do not have symptoms as yet and at the same time assess the usefulness of Brain natriuretic peptide (BNP) in doing this.
- Trial name
- NCT00400257
- Testing
- Early detection of heart failure
- Where
- Australia
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Ingrid Hopper
Heart Failure, Left Bundle-Branch Block
Direct HIS/LBB Pacing as an Alternative to Biventricular Pacing in Patients With HFrEF and a Typical LBBB.
The study will investigate the feasibility of using direct HIS pacing or left bundle branch pacing (LBB pacing) as an alternative to biventricular pacing in patients with symptomatic heart failure and an ECG with a typical left…
- Trial name
- HIS-alt_2 (NCT04409119)
- Testing
- HIS/LBB pacing, LV pacing
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pediatrics, Heart Failure
Platelet and Tissue cAMP: Novel Biomarkers of Milrinone Efficacy in Children
The purpose of this study is to identify if circulating platelet cyclic adenosine monophosphate (cAMP) levels can be used as a biomarker of milrinone efficacy in children following cardiac surgery or undergoing heart transplant.
- Conditions
- Pediatrics, Heart Failure, Congenital Heart Disease, Therapeutics
- Trial name
- NCT02728128
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Colorado, Denver
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