Clinical trials: Heart Failure, Unspecified
Heart Failure, HFpEF
Deprescribing Beta-Blockers in Elders With Heart Failure With Preserved Ejection Fraction (DEPRESCRIBE-HFpEF)
The goal of this study is to learn whether stopping beta-blockers can help older adults with heart failure with preserved ejection fraction (HFpEF) feel better and function better.
- Conditions
- Heart Failure, HFpEF, HFpEF - Heart Failure With Preserved Ejection Fraction
- Trial name
- DEPRESCRIBE (NCT07298993)
- Testing
- Beta-blockers
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Weill Medical College of Cornell University
Heart Failure, Pacing Induced Dyssynchrony
Response to Cardiac Resynchronization Therapy of Previously Right Ventricular Paced Heart Failure Patients
The present proposal is designed to investigate the response to CRT in patients who were previously paced from the right ventricle (RV).
- Trial name
- NCT01466621
- Where
- United States
- Volunteers
- 743 people
- Sponsor
- Allina Health System
Heart Failure
Health Literacy, Stress and Quality of Life in Heart Failure Patients
Heart failure is showing a trend of affecting younger individuals. Middle-aged heart failure patients are often the economic backbone of their families.
- Trial name
- NCT06923514
- Where
- Taiwan
- Volunteers
- 158 people
- Sponsor
- Cheng-Hsin General Hospital
Heart Failure, Congestive
My Recordable On-Demand Audio Discharge Instructions
Non-adherence to the heart failure (HF) plan of care after hospital discharge has been associated with clinical outcomes, including the combined endpoint of all-cause mortality and rehospitalization for decompensated HF.
- Trial name
- MyROAD (NCT02901314)
- Testing
- on-demand audio messages of heart failure education themes
- Where
- 4 sites in United States
- Volunteers
- 2,487 people
- Sponsor
- The Cleveland Clinic
Congestive Heart Failure, Diabetes
Does Access to an EHR Patient Portal Influence Chronic Disease Outcomes?
The purpose of this study is to determine if patients with congestive heart failure, diabetes or secondary cardiovascular diseases, who access HealthMedia's online tailored behavior change programs on the electronic health record…
- Conditions
- Congestive Heart Failure, Diabetes, Cardiovascular Disease
- Trial name
- NCT00147706
- Testing
- Tailored Healthmedia programs on EHR Patient Portal
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- Robert Wood Johnson Foundation
Heart Failure
Coping in Heart Failure Partnership Intervention
The purpose of this study is to examine the feasibility and preliminary effectiveness of a 12-week support and problem-solving telephone-based intervention (COPE-HF) on heart failure self-care, depression, and healthcare…
- Trial name
- COPE-HF (NCT05337293)
- Testing
- COPE-HF Partnership Intervention, Attention
- Where
- 2 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Florida State University
Heart Failure, Type 2 Diabetes
Effects of Dark Chocolate on Exercise Capacity, and Mitochondrial Structure and Function
The major goal of this study is to characterize the ability of dark chocolate enriched in epicatechin (a component of dark chocolate) to improve the structural and functional features of mitochondria in two groups 1.
- Trial name
- NCT01671514
- Testing
- Epicatechin-enriched dark chocolate, Low-epicatechin dark chocolate
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Thyroid Diseases, Heart Failure
Early Detection of Autoimmune Thyroid Heart Disease Via Urinary Exosomal Proteins
Autoimmune thyroid disease revealed close relationship with heart failure, including the entities of subclinical hyperthyroidism and hypothyroidism. Heart failure is a principal complication of all forms of heart disease.
- Trial name
- NCT03984006
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
Heart Failure
Cardiac Magnetic Resonance Imaging Guided Left Ventricular Lead Placement
Heart failure is a common, costly, disabling and potentially lethal condition. Despite well recognised and proven drug therapies, many patients remain breathless on exertion.
- Trial name
- NCT01417624
- Testing
- CMR Guidance in terms of guiding LV lead implantation
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Rheumatic Heart Disease, Heart Failure
Dapagliflozin Effect on Rheumatic Mitral Stenosis
Rheumatic mitral stenosis remains a health problem in developing countries. Progressive fibrosis of the valves and myocardium is the main pathophysiology that plays an important role.
- Conditions
- Rheumatic Heart Disease, Heart Failure, Mitral Stenosis
- Trial name
- Dapa-Rhemis (NCT05618223)
- Testing
- Dapagliflozin
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- Universitas Sebelas Maret
Heart Failure, Arteriosclerosis of Coronary Artery Bypass Graft or Other Coronary Reperfusion
PAC-IC-SAOS Obstructive Sleep Apnea Syndrome and Ventricular Function
The aim of this clinical trial is to evaluate the effect of obstructive sleep apnea syndrome (OSAS) treatment in heart failure patients following coronary artery bypass graft (CABG) surgery or other coronary reperfusion.
- Conditions
- Heart Failure, Arteriosclerosis of Coronary Artery Bypass Graft or Other Coronary Reperfusion, Sleep Apnea, Obstructive
- Trial name
- PAC-IC-SAOS (NCT01900379)
- Testing
- CPAP treatment
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Grenoble
Pneumonia, Diabetes
Social Incentives to Increase Mobility
This study aims to assess the effectiveness of a social incentive-based gamification intervention to increase physical activity in the 3 months after hospital discharge.
- Conditions
- Pneumonia, Diabetes, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- MOVE IT (NCT03321279)
- Testing
- Social Incentive
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- University of Pennsylvania
Primary Biliary Cholangitis, Heart Failure
Evidence Based Mental Wellness Programming Online for Adults Across Chronic Physical Conditions
Chronic physical conditions are defined as conditions that require ongoing management and treatment over extended periods of time.
- Conditions
- Primary Biliary Cholangitis, Heart Failure, Digestive Diseases, Women Who Have Experienced a Cardiac Event
- Trial name
- EMPOwer (NCT05786482)
- Testing
- Online mind-body wellness program, Online mind-body wellness program + Weekly Check-ins
- Where
- Canada
- Volunteers
- 825 people
- Sponsor
- University of Alberta
Aged
Frailty in Elderly Patients Receiving Cardiac Interventional Procedures
In Italy, life expectancy at birth has reached 80 years in men and 85 in women; in about 50 years, life expectancy at the age of 80 has increased by an extraordinary 61% and 55%, respectively, due to more effective therapies and…
- Trial name
- FRASER (NCT02386124)
- Testing
- frailty evaluation
- Where
- Italy
- Volunteers
- 402 people
- Sponsor
- University Hospital of Ferrara
Chronic Heart Failure
Cost and Shared Decision-Making for Heart Failure
This study is designed to understand the impact of providing patient-specific cost at the time of the clinical encounter on decision-making for heart failure medications.
- Trial name
- NCT04793880
- Testing
- Medication Cost Information, Heart Failure Medicines Checklist
- Where
- 4 sites in United States
- Volunteers
- 247 people
- Sponsor
- Emory University
Heart Failure, Systolic
Observational and Prospective Registry on Cardiac Contractility Modulation (CCM) Therapy
Observational and perspective study with acute and chronic endpoint.
- Trial name
- REPORT-CCM (NCT04902079)
- Testing
- Device for Cardiac Contractility Modulation Therapy (CCM)
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Monaldi Hospital
Breast Cancer, Cardiotoxicity
Understanding CARdiac Events in Breast Cancer
In Ireland, over 3,000 patients are diagnosed with breast cancer annually, and 1 in 9 Irish women will be diagnosed with breast cancer in their lifetime.
- Conditions
- Breast Cancer, Cardiotoxicity, Cardiomyopathies, Chemotherapeutic Toxicity
- Trial name
- UCARE (NCT05921279)
- Where
- 4 sites in Ireland
- Volunteers
- 100 people
- Sponsor
- National University of Ireland, Galway, Ireland
Cardiac Allograft Vasculopathy, Chronic Rejection of Cardiac Transplant
Heart Failure After Heart Transplantation Due to Chronic Rejection
This study will investigate the prevalence of allograft vasculopathy and unexplained graft dysfunction during long-term follow-up after heart transplantation. Risk factors as well diagnostic approaches will be investigated.
- Conditions
- Cardiac Allograft Vasculopathy, Chronic Rejection of Cardiac Transplant, Graft Dysfunction
- Trial name
- AVALON (NCT03808324)
- Testing
- Diagnostic investigations
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Heart Failure, Arrhythmia
BIO|CONCEPT.BIOMONITOR-HF Collect Clinical Data From Heart Failure Patients Using BIOMONITOR Devices With a Study Specific Research Software
[Plain language]: Heart failure (HF) patients often experience irregular heartbeats, known as arrhythmias. Atrial fibrillation (AF) is common among HF patients and can worsen their condition, leading to strokes and higher death…
- Conditions
- Heart Failure, Arrhythmia, Decompensated Heart Failure, Atrial Fibrillation
- Trial name
- NCT06989580
- Testing
- BIOMONITOR IV with study software
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 300 people
- Sponsor
- Biotronik SE & Co. KG
Heart Failure With Preserved Ejection Fraction
Right Ventricular Function and Pulmonary Hypertension in HFpEF
In patients with heart failure and preserved ejection fraction (HFpEF) right ventricular (RV) systolic and diastolic dysfunction are prognostically and functionally relevant factors but have mechanistically been neglected so far.
- Trial name
- HFpEF-PHT (NCT05055180)
- Testing
- Invasive hemodynamics and myocardial biopsies
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Heart Center Leipzig - University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.