Clinical trials: Heart Failure, Unspecified
Heart Failure; With Decompensation, Cardiorenal Syndrome
The Aortix CRS Pilot Study
The Aortix CRS Pilot Study: An Evaluation of the Safety and Performance of the Aortix System for Intra-Aortic Mechanical Circulatory Support in Patients with Cardiorenal Syndrome
- Conditions
- Heart Failure; With Decompensation, Cardiorenal Syndrome, Cardio-Renal Syndrome, Heart Failure
- Trial name
- NCT04145635
- Testing
- Aortix System
- Where
- 19 sites in United States, Australia
- Volunteers
- 21 people
- Sponsor
- Procyrion
Heart Failure
Heart Failure Self Care Education in Rwanda
In Rwanda, patients with heart failure may have low health education about their condition. Heart failure care requires active patient involvement.
- Trial name
- NCT07722468
- Testing
- HF Education
- Where
- Rwanda
- Volunteers
- 400 people
- Sponsor
- Boston Medical Center
Heart Failure
Dapagliflozin in Diabetic Patients (Type 2) With Decompensated Heart Failure
We hypothesize that Dapagliflozin could improve the diuretic response in diabetic patients with acute decompensated heart failure owing to its diuretic effect in addition to improvement of blood glucose level without remarkable…
- Trial name
- NCT04385589
- Testing
- Dapagliflozin, insulin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cardiovascular Events
A Randomized Controlled Trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly People
This study was planned to provide new information regarding the role of aliskiren (with or without additional therapy with a diuretic or a Calcium channel blockers (CCB)) in elderly individuals (≥ 65 years) with systolic blood…
- Trial name
- APOLLO (NCT01259297)
- Testing
- Aliskiren, Amlodipine, Hydrochlorothiazide (HCTZ)
- Where
- 185 sites in United States, Argentina and 16 more
- Volunteers
- 2,336 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure, Heart Diseases
Flexible vs. Fixed Diuretic Regimen in the Management of Chronic Heart Failure: A Pilot Study
Heart failure is a major cause of death and hospitalization in Canada. Many of the symptoms experienced by patients with heart failure relate to having fluid accumulate in the lungs causing difficulty breathing, swelling in the…
- Trial name
- NCT05594823
- Testing
- Ambulatory heart failure management with Flexible Diuretic Regimen with furosemide, Ambulatory heart failure management with fixed dose furosemide
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Heart Failure
Interactive Patient's Assistant - LUCY
Patients with chronic heart failure (CHF) and reduced left ventricle ejection fraction benefit from cardiac resynchronization therapy (CRT) and implantable cardioverter defibrillator (ICD).
- Trial name
- NCT03474315
- Testing
- Multivariate assessment
- Where
- Poland
- Volunteers
- 600 people
- Sponsor
- Medical University of Warsaw
Obesity, Heart Failure With Preserved Ejection Fraction (HFpEF)
A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial
The main purpose of this study is to assess the efficacy and safety of Tirzepatide (LY3298176) in participants with heart failure with preserved ejection fraction and obesity.
- Trial name
- NCT04847557
- Testing
- Tirzepatide
- Where
- 146 sites in United States, Argentina and 8 more
- Volunteers
- 731 people
- Sponsor
- Eli Lilly and Company
Heart Failure
A Novel Echocardiography Modality to Assess Left Ventricular Dyssynchrony
The investigators hypothesize that the relation between mechanical and hemodynamic left ventricular dyssynchrony might better predict response to Cardiac Resynchronization Device(CRT) than currently existing echo indices.
- Trial name
- NCT01007981
- Sponsor
- University of Missouri-Columbia
Heart Failure, Heart Failure NYHA Class III
Narrative Intervention for Chronic Illness- Heart Failure Trial (NICI-HF)
The Narrative Intervention for Chronic Illness-Heart Failure (NICI-HF) offers an asynchronous interactive text behavioral health intervention to advance behavioral health equity by facilitating access to care for people adjusting…
- Conditions
- Heart Failure, Heart Failure NYHA Class III, Heart Failure NYHA Class IV
- Trial name
- NICI-HF (NCT06097481)
- Testing
- Narrative Intervention for Chronic Illness-Heart Failure, Attention Control
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Heart Failure, Cardiac Remodeling, Ventricular
Biological Mechanisms Behind Resynchronization Therapy in Heart Failure
Heart failure is a common disease, affecting 2-3% of the population in the western world. About 30% of patients with heart failure and reduced ejection fraction display signs of electrical dyssynchrony on ECG, usually left bundle…
- Trial name
- NCT06140914
- Testing
- Proteomics, miRNA studies and studies of blood cells from blood samples
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Region Stockholm
Obesity, Heart Failure With Preserved Ejection Fraction (HFPEF)
A Study of IBI362 in Subjects With HFpEF or HFmrEF Combined With Obesity
This is a multicenter, randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and safety of IBI362 in Chinese subjects with heart failure with ejection fraction retention/mild ejection fraction…
- Conditions
- Obesity, Heart Failure With Preserved Ejection Fraction (HFPEF), Heart Failure With Mildly Reduced Ejection Fraction
- Trial name
- NCT06862908
- Testing
- IBI362
- Where
- China
- Volunteers
- 141 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Heart Failure
Psychosocial Syndemics of Heart Failure
Heart failure (HF) is a common and debilitating chronic disease with a poor prognosis. Many patients with HFhave psychiatric problems such as depression and other medical disorders such as lung or kidney disease.This study will…
- Trial name
- NCT04637776
- Testing
- Hospitalization
- Where
- United States
- Volunteers
- 367 people
- Sponsor
- Washington University School of Medicine
Heart Failure, Congestive Heart Failure
Evaluation of the Safety and Efficacy of the 2-lead OPTIMIZER® Smart System
This is a multicenter, prospective, single-arm study of the Optimizer Smart System with 2-leads
- Conditions
- Heart Failure, Congestive Heart Failure, Chronic Heart Disease, CHF
- Trial name
- FIX-HF-5C2 (NCT03339310)
- Testing
- Optimizer Smart System with 2-leads
- Where
- 10 sites in United States, Germany
- Volunteers
- 60 people
- Sponsor
- Impulse Dynamics
Fetal Heart Failure, Fetal Movement Disorder
Tactile Stimulus, Music Play and Virtual Reality Video Watching During Non-Stress Test on Maternal Anxiety and Fetal Parameters
The research was carried out to determine the effects of tactile stimulation, music listening and virtual reality video watched during the non-stress test on maternal anxiety level and fetal parameters.
- Trial name
- NCT05492058
- Testing
- tactile stimulation group, listen music, virtual reality group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Adiyaman University Research Hospital
Rheumatic Heart Disease, Heart Failure
Gliflozins on HF in Regurgitant Rheumatic Heart
The objective of this trial is to detect impact of Gliflozin on patients with heart failure due to reurgitant rheumatic valve disease
- Trial name
- NCT06097585
- Testing
- SGLT2 inhibitor
- Volunteers
- 150 people
- Sponsor
- Assiut University
Strength Training Effects, HFrEF - Heart Failure With Reduced Ejection Fraction
Eccentric Muscle Training in Cardiac Rehabilitation
The goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used.
- Trial name
- NCT07636343
- Testing
- eccentric bike training, eccentric overload training, aerobic treadmill training
- Where
- Belgium
- Volunteers
- 3 people
- Sponsor
- University Hospital, Antwerp
Systolic Heart Failure
Spinal Cord Stimulation For Heart Failure
The primary objectives of this feasibility study are to determine the safety of spinal cord stimulation (SCS) as a therapy in patients with systolic heart failure and to gather observational information for potential efficacy…
- Trial name
- SCS HEART (NCT01362725)
- Testing
- Spinal cord stimulation system
- Where
- 5 sites in Australia, Hong Kong and 1 more
- Volunteers
- 20 people
- Sponsor
- Abbott Medical Devices
Heart Failure, Systolic
Paced Heart Rate Acceleration for Cardiac Conditioning
A clinical trial of exercise-similar heart rate acceleration delivered via cardiac pacing vs. sham intervention in subjects at rest will be performed.
- Trial name
- HeartExcel (NCT06332391)
- Testing
- Exercise-similar cardiac pacing
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Denice Hodgson-Zingman, MD
Cardiovascular Diseases (CVD), Coronary Heart Disease (CHD)
Comparison of Two Gait Re-training Modalities During a Cardiac Rehabilitation Stay: Benefit of Orienteering Walking
Cardiovascular disease (CVD) is the leading cause of death in France for women and the second leading cause of death for men after cancer.
- Conditions
- Cardiovascular Diseases (CVD), Coronary Heart Disease (CHD), Heart Failure, Congenital Heart Disease
- Trial name
- CAMCO (NCT06941597)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Fondation Ildys
Heart Failure, Hypertension, Pulmonary
Measurement of Endothelial Function and Cardiac Output: New Methods
The main purpose of this study is to analyse test-retest-reliability of functional quantification of endothelial dysfunction through puls-amplitude-tonometry in patients with heart failure with preserved/reduced ejection…
- Conditions
- Heart Failure, Hypertension, Pulmonary, Hypertension, Diabetic Nephropathies
- Trial name
- NCT02299960
- Testing
- Endo-PAT, NICOM
- Where
- Germany
- Volunteers
- 101 people
- Sponsor
- Charite University, Berlin, Germany
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