Clinical trials: Heart Failure, Unspecified
Heart Failure, Fatigue
The Effect of Breathing Exercise on Fatigue in Heart Failure Patients
In this study, It is aimed to evaluate the effect of breathing exercise on fatigue in patients with heart failure, to reduce the severity of fatigue in participants, and thus to enable patients to participate more actively in…
- Trial name
- NCT05129371
- Testing
- Breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Mustafa Kemal University
Congestive Heart Failure
Feasibility Study of BMAC Enhanced CABG
Patients undergoing CABG will have 60 mL of bone marrow drawn, concentrated in a SmartPRep2 centrifuge and have the concentrated nucleated cells injected into areas of ischemic myocardium
- Trial name
- NCT01074099
- Testing
- BMAC, CABG only
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Harvest Technologies
Congestive Heart Failure, Atrial Fibrillation
Ventricular Rate Regularization for Improved Quality of Life in Patients With CHF and AF
Single center investigator initiated sponsored by Guidant Boston Scientific Corp. to evaluate the benefit of ventricular rate regularization (VRR) in patients with congestive heart failure (CHF) and significant atrial…
- Trial name
- VRR (NCT00583921)
- Sponsor
- University of California, Davis
Vascular Disease, Heart Disease
Effects of Urocortins on Forearm Arterial Blood Flow in Healthy Volunteers (Protocol 3)
Impairment of the heart's pumping capacity (heart failure) remains a major clinical problem with a poor prognosis and the search for novel treatments remains an important area of research.
- Trial name
- NCT01096706
- Testing
- NO clamp, Saline, Fluconazole
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Hypertension, Pulmonary, Cardiac Failure
Levosimendan Administration in Pulmonary Hypertension
The aim of the study is to examine the pharmacokinetics and pharmacodynamic properties of Levosimendan in cardiac surgery patients with pulmonary hypertension and impaired right ventricular function.
- Conditions
- Hypertension, Pulmonary, Cardiac Failure, Pulmonary Vascular Resistance Abnormality
- Trial name
- Levosim-PH (NCT04599816)
- Testing
- levosimendan at a dose of 3 mcg/kg, levosimendan at a dose of 6 mcg/kg, levosimendan at a dose of 12 mcg/kg
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- Aretaieion University Hospital
Heart Failure, Electric Impedance
Effect of Diuretics Withdrawal in Chronic Heart Failure With Reduced Ejection Fraction
REDICAE trial was designed to evaluate the safety and tolerability of diuretics withdrawal in stable, euvolemic chronic outpatients with heart failure with reduced ejection fraction.
- Conditions
- Heart Failure, Electric Impedance, Dyspnea, Safety
- Trial name
- REDICAE (NCT05964738)
- Testing
- Diuretics withdrawal, Diuretics maintenance
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Heart Failure, Myocardial Infarction
Incidence of and Prognostic Factors Associated With Heart Failure Following Myocardial Infarction: a CALIBER Study
The main objectives of this study are: i) to investigate the incidence and prevalence of fatal and non-fatal heart failure (HF) following myocardial infarction (MI) and its evolution over time in men and in women; ii) to identify…
- Trial name
- iHF (NCT02384213)
- Where
- United Kingdom
- Volunteers
- 55,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Heart Failure, Acute Decompensated Heart Failure
Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic Resistance
Evaluation of the safety and efficacy of the ModulHeart System in patients hospitalized with acute decompensated heart failure (ADHF) and diuretic resistance
- Conditions
- Heart Failure, Acute Decompensated Heart Failure, Cardiorenal Syndrome, Heart Failure, Congestive
- Trial name
- NCT06174623
- Testing
- ModulHeart Support
- Where
- 5 sites in Australia, Georgia
- Volunteers
- 5 people
- Sponsor
- Puzzle Medical Devices Inc.
Acute Heart Failure, Acute Renal Failure
Recombinant BNP on Heart and Renal Function in Acute Heart Failure
The purpose of this study is to evaluate the efficacy and safety of recombinant human B-type natriuretic peptide (rhBNP) on heart and renal function in patients with acute decompensated heart failure (ADHF) and acute renal injury…
- Trial name
- NCT01625403
- Testing
- rhBNP, standard of care
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Chest Hospital
Nutrition, Healthy, Heart Failure
The Effect of Medium-chain Fatty Acids on Cardiac Function
The effect of an acute intake of medium-chain fatty acids on heart function measured by cardiac magnetic resonance imaging (CMR) will be measured in individuals with heart failure with reduced ejection fraction (HFrEF) and in…
- Trial name
- MediHeart (NCT06399354)
- Testing
- acute intake of medium-chain fatty acids or long-chain fatty acids in patients, Acute intake of medium-chain fatty acids or long-chain fatty acids in healthy individuals
- Where
- Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Heart Failure, Atrial Arrhythmia
Restoring Sinus Rhythm With Cardiac Resynchronization in Patients With Atrial Fibrillation (ReSync AF)
Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes.
- Trial name
- NCT00268294
- Testing
- Cardiac Resynchronization Therapy
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Acute Heart Failure, Pulmonary Congestion
LUS in Acute Heart Failure Therapeutic Adaptation
Evaluate lung ultrasound aspect according to diuretics dosage evolution in patients hospitalized for acute heart failure.
- Trial name
- EPPICA (NCT04633629)
- Testing
- Lung ultrasound
- Volunteers
- 94 people
- Sponsor
- University Hospital, Grenoble
Atrial Fibrillation (AF), Heart Failure
Microbiota-Inflammation-Brain Axis in Heart Failure: New Functional Food for the Prevention of undeRnutrition in Older
The goal of this clinical trial is to learn if the AMBROSIA Bar helps prevent undernutrition and muscle loss in older adults with heart failure or atrial fibrillation.
- Trial name
- AMBROSIA (NCT07076329)
- Testing
- Ambrosia bar
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Heart Failure, Left Sided, Left Ventricular Dysfunction
Role of Sacubitril/Valsartan in the Improvement of Heart Failure With Reduced Ejection Fraction
This prospective study evaluates the mechanisms of benefit of sacubitril/valsartan in a population of outpatients with heart failure with reduced ejection fraction, to investigate the relationship between the effects on left…
- Conditions
- Heart Failure, Left Sided, Left Ventricular Dysfunction, Ventricular Remodeling
- Trial name
- NCT04397302
- Testing
- Role of Sacubitril/Valsartan in Hemodynamic and Echocardiographic Improvement of Heart Failure With Reduced Ejection Fraction
- Where
- Italy
- Volunteers
- 652 people
- Sponsor
- Italian Society of Cardiology
Acute Coronary Syndrome, Myocardial Infarction
RAMP 200 / RAMP Cardiovascular Tests at the Point-of-Care
This clinical investigation is designed to demonstrate the performance characteristics of the RAMP® cardiac tests analyzed on the RAMP® 200 by non-laboratorial Operators at the point-of-care when compared to the results for the…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Heart Failure, Congestive Heart Failure
- Trial name
- C-POC (NCT02191735)
- Testing
- RAMP 200, RAMP Reader
- Where
- 3 sites in United States
- Volunteers
- 719 people
- Sponsor
- Response Biomedical Corp.
Heart Failure With Intraventricular Conduction Delay
A Combined Transvenous and Epicardial Lead Placement Procedure for Implantation of Cardiac Resynchronization Devices: a Feasibility Study.
Cardiac resynchronization therapy has become one of the cornerstones of the treatment of heart failure. However, a large proportion of patients still fails to this type of therapy.
- Trial name
- NCT02247817
- Testing
- Hybrid CRT-D/P implantation
- Volunteers
- 10 people
- Sponsor
- University Medical Center Groningen
Heart Failure
CRT RENEWAL Registry
This registry will provide detailed patient demographics and characteristics at the time of enrollment and will also provide data regarding predictors of clinical outcomes such as heart failure decompensation, heart failure…
- Trial name
- NCT00146874
- Testing
- cardiac resynchronization therapy
- Volunteers
- 1,000 people
- Sponsor
- Boston Scientific Corporation
Heart Failure With Preserved Ejection Fraction, Renal Denervation
Renal Denervation in Patients With Chronic Heart Failure With Preserved Ejection Fraction
This study aims to explore the potential of RDN as a therapy for HFpEF in a Prospective, Multicenter, Randomized, Blinded, Sham-controlled Study.
- Trial name
- RDN-HFPEF (NCT05715697)
- Testing
- Renal denervation and maintenance of heart failure medications
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xinjiang Medical University
Heart Failure
Effect of a Quality Improvement Initiative to Address Social Determinants of Health on Rehospitalization Rates in Patients With Heart Failure
The objective of this program is to improve post-acute care coordination for necessary social services for patients leaving the hospital after recovering from an episode of decompensated heart failure.
- Trial name
- NCT05388097
- Testing
- Managed Services
- Where
- 3 sites in United States
- Volunteers
- 320 people
- Sponsor
- Saint Luke's Health System
Heart Failure
Post- Approval Study on Patients Who Received a HeartWare HVAD® During IDE Trials
Patients will be approached to participate in this PAS after the HeartWare® Ventricular Assist System receives PMA approval for the indicated use as a bridge to cardiac transplantation.
- Trial name
- HW-PAS-03 (NCT01832610)
- Testing
- HeartWare® VAS
- Where
- 25 sites in United States
- Volunteers
- 101 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
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