Clinical trials: Heart Failure, suspended
Worsening Heart Failure
CRF2 Agonist for the Treatment of Worsening Heart Failure
This study assesses the effects of the investigational drug COR-1167 in subjects hospitalised due to worsening of heart failure (HF)
- Trial name
- CRAFT-WHF (NCT06815471)
- Testing
- COR-1167
- Where
- 55 sites in United States, Czechia and 6 more
- Volunteers
- 300 people
- Sponsor
- Corteria Pharmaceuticals
Heart Failure With Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study
Prospective, randomized, open-label, international, multi-center clinical study to evaluate the safety and efficacy of the AccuCinch Ventricular Restoration System in patients with heart failure and reduced ejection fraction…
- Trial name
- NCT04331769
- Testing
- AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
- Where
- 122 sites in United States, Belarus and 8 more
- Volunteers
- 400 people
- Sponsor
- Ancora Heart, Inc.
Heart Failure
Prospective Multi-Center Randomized Study for Evaluating the EVAHEART®2 Left Ventricular Assist System
This is a prospective, multi-center, unblinded, randomized, controlled, and non-inferiority study comparing the EVA2 LVAS to the most recent magnetically levitated centrifugal LVAS (HM3 LVAS).
- Trial name
- COMPETENCE (NCT01187368)
- Testing
- EVAHEART Left Ventricular Assist System (LVAS), HeartMate 3
- Where
- 12 sites in United States
- Volunteers
- 399 people
- Sponsor
- Evaheart, Inc.
Heart Failure
The Study of Heart Failure With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-HF)
The purposes of the study is to evaluate the safety and efficacy of human umbilical cord mesenchymal stem cells (hUC-MSC) in treating heart failure patients
- Trial name
- NCT03180450
- Testing
- Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#), conventional treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sclnow Biotechnology Co., Ltd.
Advanced Heart Failure
European Clinical Evaluation of the Carmat Total Artificial Heart
The objective of this clinical investigation is to evaluate the safety and performance of the Carmat Total Artificial Heart (TAH) in subjects with advanced heart failure requiring biventricular support.
- Trial name
- ADVANCEHF (NCT02962973)
- Testing
- CARMAT TAH, Surgical intervention
- Where
- 2 sites in Kazakhstan, Netherlands
- Volunteers
- 20 people
- Sponsor
- Carmat SAS
End-stage Heart Failure
Carmat TAH Early Feasibility Study
Feasibility study of the Carmat TAH as a treatment for transplant-eligible patients in severe, end-stage heart failure.
- Trial name
- NCT04117295
- Testing
- Carmat Total Artificial Heart
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Carmat SAS
Congestive Heart Failure
VITARIA Registry Study
This registry will observe patients with symptomatic heart failure with implantable vagus nerve stimulation to provide insights into safety and efficacy during clinical routine.
- Trial name
- NCT02545582
- Testing
- VITARIA System
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Cyberonics, Inc.
Heart Failure, Mitral Regurgitation
Study of Safety and Efficacy of the Percutaneous Reduction of Mitral Valve Regurgitation in Heart Failure Patients
Improvement in heart failure with moderate to severe mitral regurgitation using a percutaneously delivered implantable device.
- Trial name
- PTOLEMY-2 (NCT00787293)
- Testing
- PTMA (Percutaneous Transvenous Mitral Annuloplasty) Implant
- Where
- 13 sites in Belgium, Czechia and 3 more
- Volunteers
- 30 people
- Sponsor
- Viacor
Mitral Regurgitation, Heart Failure
Safety and Efficacy Study of the PTMA Device to Reduce Mitral Valve Regurgitation in Patients With Heart Failure
Improvement in heart failure with moderate to severe mitral regurgitation using a percutaneously delivered implantable device residing in the coronary sinus
- Trial name
- PTOLEMY2Canada (NCT00815386)
- Testing
- Percutaneous transvenous mitral annuloplasty
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Viacor