Clinical trials: Heart Infarction
Myocardial Infarction
Cognitive Behavioral Therapy Following Myocardial Infarction
Myocardial infarction (MI) is one of the leading cause s of health loss globally, representing a large proportion of general disability.
- Trial name
- MI-CBT (NCT04649307)
- Testing
- MI-CBT
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Karolinska Institutet
ST-segment Elevation Myocardial Infarction (STEMI)
The Effect of Morning vs Evening Aerobic Exercise Training on Cardiac Remodeling and Function Improvement in Patients After ST Elevation Myocardial Infarction
The aim of the study was to intervene in the Aerobic exercise time of patients with STEMI and to explore the optimal exercise time for STEMI patients
- Trial name
- NCT06385834
- Testing
- Morning aerobic exercise, Evening aerobic exercise
- Where
- China
- Volunteers
- 201 people
- Sponsor
- RenJi Hospital
Ischemic Cardiomyopathy
Genetics of Ischemic Cardiomyopathy
Background:Ischemic heart disease is one of the heaviest health-related burdens worldwide.We aimed to identify the common hub mRNA and pathways that are involved in pathological progression of ischemic cardiomyopathy.
- Trial name
- NCT05508269
- Testing
- quantitative polymerase chain reaction(QPCR) for four genes, Cardiac biopsy, blood sampling
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Coronary Syndrome, STEMI - ST-segment Elevation Myocardial Infarction
Kitasato PCI Registry
The Kitasato PCI Registry is a single-center, observational, prospective study. This study aims to investigate the impact of characteristics in clinical manifestation, patients' background, procedure of percutaneous coronary…
- Conditions
- Acute Coronary Syndrome, STEMI - ST-segment Elevation Myocardial Infarction, NSTEMI - Non-ST-Segment Elevation Myocardial Infarction, Atherosclerosis
- Trial name
- NCT05308329
- Testing
- Intra-coronary imaging device, PCI procedural characteristics
- Where
- Japan
- Volunteers
- 4,500 people
- Sponsor
- Kitasato University
Acute Myocardial Infarction, Cardiac Rehabilitation
Effect of Digital Therapeutics for Cardiac Rehabilitation in Patients With Acute Myocardial Infarction
This study adopts a multicenter, open-label, randomized controlled clinical study, with Jiangsu Provincial People's Hospital as the leading unit, and the other 13 hospitals as cooperative units.
- Trial name
- NCT06772337
- Testing
- digital cardiac rehabilitation, Regular Treatment
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Critical Illness, Myocardial Infarction
The Short and Long-term Cardiovascular Consequences of Critical Illness: The C3 Study
The aim this study will be to find out which patients are at risk of heart attacks/strokes up to several years after discharge from an ICU.
- Conditions
- Critical Illness, Myocardial Infarction, Stroke, Atrium; Fibrillation
- Trial name
- C3 (NCT04545437)
- Testing
- Admission to ICU
- Where
- 3 sites in United Kingdom
- Volunteers
- 80,000 people
- Sponsor
- University of Oxford
STEMI, Myocardial Reperfusion Injury
Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI)
The purpose of this study is to determine whether remote ischemic conditioning can reduce cardiac death and hospitalization for heart failure at 12 months in patients presenting with a ST-elevation myocardial infarction and…
- Trial name
- NCT02342522
- Testing
- Remote ischemic conditioning, Control
- Where
- 35 sites in Denmark, Serbia and 2 more
- Volunteers
- 5,413 people
- Sponsor
- University College, London
Acute Myocardial Infarction (AMI), Asystole
SPIKE FLOW Endocardial Lead Safety and Performance Study
The objective of this study is to assess the safety and performance of the SPIKE FLOW endocardial lead. Primary objectives are to assess: safety in terms of freedom from Serious Adverse Events(SADEs); performance in terms of Mean…
- Conditions
- Acute Myocardial Infarction (AMI), Asystole, Bradycardia, AV Block
- Trial name
- SPIKE FLOW (NCT07820072)
- Testing
- Lead insertion, lead removal
- Where
- 3 sites in Italy
- Volunteers
- 131 people
- Sponsor
- FIAB SpA
Myocardial Infarction
A Structuralised Sick-leave Program Compared to Usual Care Sick Leave Management in Patients After an Acute Myocardial Infarction
In this study the investigators aim at comparing the effect on quality of life and the cost-effectiveness of a structuralised sick-leave program compared to usual care sick leave management in patients after an acute non ST…
- Trial name
- NCT01108653
- Testing
- Usual care sick-leave management, Structuralised sick-leave program
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
STEMI - ST Elevation Myocardial Infarction, Thrombi
Pan-Cardio-Genetics Clot Assessment in Acute Coronary Syndromes
Acute myocardial infarction with ST elevation (STEMI) is one of the leading causes of mortality. Although the presence of thrombus in STEMI patients has been linked to adverse outcomes, routine thrombus aspiration has not been…
- Conditions
- STEMI - ST Elevation Myocardial Infarction, Thrombi, MicroRNA
- Trial name
- PGCA-ACS (NCT03832153)
- Testing
- thrombus aspiration
- Where
- Greece
- Sponsor
- Aristotle University Of Thessaloniki
Acute Myocardial Infarction
An Observational Study of TNKase in Patients Enrolled in the National Registry of Myocardial Infarction 4 and 5 (POST)
The POST study comprised patients whose data were entered into the NRMI 4 and 5 databases. NRMI is a prospective, observational study of patients presenting with AMI in the United States.
- Trial name
- NCT00669045
- Volunteers
- 253,668 people
- Sponsor
- Genentech, Inc.
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)
Study of heterogeneity in associations between heart rate and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Coronary Death, Intracerebral Haemorrhage
- Trial name
- NCT01947361
- Where
- United Kingdom
- Volunteers
- 1,961,286 people, healthy volunteers welcome
- Sponsor
- University College, London
Atherosclerosis, Coronary Artery Disease
National Plaque Registry and Database
The ultimate goal of this project is to develop a risk score to identify patients with vulnerable coronary atherosclerotic plaques, who are prone to suffer acute coronary syndrome.
- Conditions
- Atherosclerosis, Coronary Artery Disease, Cardiovascular Disease
- Trial name
- OPeRA (NCT02578355)
- Where
- 11 sites in Hungary
- Volunteers
- 20,000 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Pregnancy, Pulmonary Embolism
Identify Clinical Conditions That Increase Circulating DNA Levels
The investigators are developing a test that is expected to measure the amount of radiation a patient has been exposed to after a nuclear bomb.
- Conditions
- Pregnancy, Pulmonary Embolism, Myocardial Infarction, Autoimmune Disease
- Trial name
- BARDA II (NCT01815996)
- Testing
- One time blood draw to look at patient's DNA
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Florida
Myocardial Infarction, Cardiovascular Death
Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin
This study is being carried out to see if a new drug called ticagrelor given twice daily in addition to the ASA therapy decreases the frequency of cardiovascular events (e.g., death from heart disease, heart attack, or stroke).
- Conditions
- Myocardial Infarction, Cardiovascular Death, Atherothrombosis, Stroke
- Trial name
- PEGASUS (NCT01225562)
- Testing
- Ticagrelor 90 mg, Ticagrelor 60 mg
- Where
- 826 sites in United States, Argentina and 29 more
- Volunteers
- 21,379 people
- Sponsor
- AstraZeneca
Coronary Artery Disease, ST Elevation Myocardial Infarction
Prognostic Implications of AccuFFRangio-guided PCI in STEMI
This is a prospective, single-center clinical trial. AccuFFRangio (ArteryFlow Technology Co., Ltd., Hangzhou, China) is a novel method for evaluating the functional significance of coronary stenosis by computing the pressure in…
- Trial name
- NCT05209503
- Testing
- AccuFFRangio-guided strategy, Angiography-guided strategy
- Volunteers
- 500 people
- Sponsor
- Wuhan Asia Heart Hospital
Myocardial Infarction
A Study to Evaluate the Use of Mobile-phone Based Patient Support in Patients Diagnosed With Myocardial Infarction
The purpose of this study is to evaluate whether the mobile-phone based patient support has an impact on the adherence and persistence of ticagrelor treatment or on lifestyle changes that will have a positive impact on the…
- Trial name
- SUPPORT (NCT01874262)
- Testing
- Mobile-phone based patient support, e-diary
- Where
- 13 sites in Sweden
- Volunteers
- 174 people
- Sponsor
- AstraZeneca
Acute Coronary Syndromes, STEMI
Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary Syndrome
This is a prospective, open-label, multicenter, randomized, phase IV clinical trial designed to evaluate the safety and efficacy of early aspirin discontinuation followed by potent P2Y12 inhibitor monotherapy after intravascular…
- Conditions
- Acute Coronary Syndromes, STEMI, NSTEMI, Unstable Angina
- Trial name
- SAPT-ACS (NCT07684742)
- Testing
- Early P2Y12 Inhibitor Monotherapy, Standard Dual Antiplatelet Therapy
- Where
- South Korea
- Volunteers
- 1,900 people
- Sponsor
- Gyeongsang National University Hospital
Myocardial Infarction, STEMI
The Effect of 12 Lead ECG Telemetry on Reperfusion Time in Resource-limited Settings
This study aims to determine whether prehospital 12 lead ECG telemetry decreases the time to reperfusion in patients presenting with STEMI.
- Trial name
- NCT02441582
- Testing
- Telemetry, Non-telemetry
- Where
- 2 sites in South Africa
- Volunteers
- 19 people
- Sponsor
- Karolinska Institutet
ST-segment Elevation Myocardial Infarction (STEMI)
The Prognostic Value of Anion Gap in Predicting Major Adverse Cardiovascular Events Among Patients With ST-Segment Elevation Myocardial Infarction
This study aims to evaluate the prognostic value of the anion gap in predicting major adverse cardiovascular events among patients with ST-segment elevation myocardial infarction.
- Trial name
- ANGIO-STEMI (NCT06586424)
- Testing
- Anion gap
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Diponegoro
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