Clinical trials: Heart Infarction
Atrial Fibrillation, Ischemic Stroke
Direct Oral Anticoagulants in Patients With Atrial Fibrillation (DOACs vs DOACs)
The purpose of this study is to assess safety and effectiveness of direct oral anticoagulants (DOACs) for stroke prevention in patients with non-valvular atrial fibrillation (AF).
- Conditions
- Atrial Fibrillation, Ischemic Stroke, Systemic Embolization, Major Bleed
- Trial name
- NCT03568916
- Testing
- Apixaban (ATC B01AF02), Dabigatran (ATC B01AE07), Rivaroxaban (ATC B01AF01)
- Where
- Canada
- Volunteers
- 227,579 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
Myocardial Ischemia, Myocardial Infarction
Magnetic Resonance Technique in the Assessment of Exercise-induced Long- and Short-Term Changes in Cardiac Function and Morphology
Until now it has been assumed that regular endurance training has a positive influence on cardiac function and that the positive effect increases with increasing intensity.
- Conditions
- Myocardial Ischemia, Myocardial Infarction, Ventricular Remodeling, Myocardial Contraction
- Trial name
- NCT01305304
- Testing
- repeated long term endurance exercise, Other
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Artery Diseases, Myocardial Infarction
The Efficacy of Influenza Vaccine in Reducing Cardiovascular Events in Patients With Coronary Artery Diseases
Influenza vaccine reduces the cardiovascular events in post-myocardial infarction (MI) patients and in those with stable angina (SA).
- Conditions
- Coronary Artery Diseases, Myocardial Infarction, Stable Angina
- Trial name
- IVCAD (NCT00607178)
- Testing
- influenza vaccine
- Where
- Iran
- Volunteers
- 300 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Myocardial Infarction, Ischemia
A Randomized Trial of Early Discharge After Trans-radial Stenting of Coronary Arteries in Acute MI
HYPOTHESES 1. Bolus administration of total abciximab dose provides superior maximal and mean platelet aggregation inhibition (PAI) compared with standard bolus (0.25 mg/kg) administration. 2.
- Trial name
- EASY-MI (NCT00440778)
- Testing
- Abciximab
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Laval University
Myocardial Infarction
An Integrative Cardiac Rehabilitation Employing Smartphone Technology (iCREST)
Aim: To develop and field test an Integrative Cardiac Rehabilitation Employing Smartphone Technology (I-CREST) system, and evaluate its effects on CR utilization, cardiac self-efficacy, functional capacity, health-related quality…
- Trial name
- I-CREST (NCT05270993)
- Testing
- Traditional Centre-based Cardiac Rehabilitation (CBCR) group, I-CREST group
- Where
- Singapore
- Volunteers
- 124 people
- Sponsor
- National University of Singapore
Coronary Artery Diseases
BIOTRONIK - BIOFLOW-III Registry French Satellite
For the majority of Coronary Artery Disease (CAD) treatment with Percutaneous Transluminal Coronary Angioplasty (PTCA) provides high initial procedure success.
- Trial name
- NCT02273648
- Testing
- Drug Eluting Stent (DES)
- Where
- 50 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Biotronik France
ST-elevation MI, Hypothermia
Evaluation of Ultrafast Hypothermia Before Reperfusion in STEMI Patients
This study will look at the safety of treating patients with heart attack with mild hypothermia induced using a system of automated peritoneal lavage.
- Trial name
- VELOCITY (NCT01655433)
- Testing
- Velomedix APLS device, No Hypothermia Treatment
- Where
- 7 sites in United States, Canada
- Volunteers
- 54 people
- Sponsor
- Velomedix, Inc.
Myocardial Infarction, Acute
Effect of INtravenous FERRic Carboxymaltose Onmortality and Cardiovascular Morbidity, and Quality of Life in Iron Deficient Patients With Recent Myocardial infarCTion
Non-commercial, multicentre, randomised, double-blind, parallel group, placebo-controlled clinical trial. Eligible patients were randomly assigned (1:1) using a secure, central, interactive, web-based response system, to…
- Trial name
- INFERRCT (NCT05759078)
- Testing
- Ferinject, Sodium Chloride 0.9% Inj
- Where
- 43 sites in Poland
- Volunteers
- 1,000 people
- Sponsor
- Wroclaw Medical University
Myocardial Infarction, Chest Pain
AI-based Decision Support in Acute Chest Pain
The AIDE-CP1 trial will test whether a decision support tool based on artificial intelligence (AI) can improve care for patients who come to an emergency department with chest pain.
- Trial name
- AIDE-CP1 (NCT07864038)
- Testing
- AIDE-CP available
- Volunteers
- 4,500 people
- Sponsor
- Region Skane
Myocardial Infarction
The Effects of mETHotrexate Therapy on ST Segment Elevation MYocardial InfarctionS (TETHYS Trial)
Experimental studies suggest that anti-inflammatory and immunomodulatory drugs could reduce the inflammatory profile in acute ischemic disease and reduce the area of ischemia.
- Trial name
- TETHYS (NCT01741558)
- Testing
- Methotrexate, Riboflavin
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
ST Segment Elevation Myocardial Infarction
Facilitation Through Aggrastat By drOpping or Shortening Infusion Line in Patients With ST-segment Elevation Myocardial Infarction Compared to or on Top of PRasugrel Loading dOse
This is a single-centre, open-label prospective randomized pharmacodynamic investigation of 2 antiplatelet regimens in patients undergoing coronary intervention for ST segment elevation myocardial infarction(STEMI): 1.
- Trial name
- FABOLUS PRO (NCT01336348)
- Testing
- Prasugrel, Tirofiban
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi di Ferrara
Acute Myocardial Infarction, Coronary Artery Disease
Cardiac MRI for Patients Enrolled in INFUSE-AMI
Background: INFUSE AMI is an ongoing clinical trial examining how patients with heart attacks are treated. The study's aim is to help determine the best way to treat patients with specific kinds of heart attacks caused by blood…
- Conditions
- Acute Myocardial Infarction, Coronary Artery Disease, Myocardial Fibrosis, Gadolinium
- Trial name
- NCT01059214
- Where
- United States
- Volunteers
- 455 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Coronary Syndrome (ACS)
Lp(a) Lowering Study of Pelacarsen (TQJ230) in Patients in the US With Elevated Lp(a) and Recent ACS (STEMI/NSTEMI) - Lp(a)FRONTIERS PEARL
CTQJ230A1US13 is a randomized, double-blind, placebo-controlled, multicenter phase IIIb study designed to evaluate the efficacy, safety, tolerability, and coronary plaque effects of early pelacarsen (TQJ230) initiation in…
- Trial name
- NCT07625306
- Testing
- Pelacarsen
- Sponsor
- Novartis Pharmaceuticals
ST-elevation Myocardial Infarction (STEMI), Acute Myocardial Infarction (AMI)
Timing of Empagliflozin in Primary PCI: Pre-Reperfusion Versus Post-Reperfusion Versus Placebo in South Asian STEMI Patients
The goal of this clinical trial is to learn if giving the drug empagliflozin before versus after a heart procedure called primary PCI (percutaneous coronary intervention) affects how much heart muscle is damaged during a heart…
- Conditions
- ST-elevation Myocardial Infarction (STEMI), Acute Myocardial Infarction (AMI), Coronary Artery Disease
- Trial name
- TEMPO-STEMI (NCT07749014)
- Testing
- empagliflozin
- Where
- Pakistan
- Volunteers
- 480 people
- Sponsor
- Rehman Medical Institute - RMI
Acute Myocardial Infarction
SILVER-AMI: Outcomes in Older Persons With Heart Attacks
SILVER-AMI is a research study of older persons who are admitted to the hospital with a heart attack. Patients will be interviewed in the hospital and again 6 months later.
- Trial name
- SILVER-AMI (NCT01755052)
- Where
- 81 sites in United States
- Volunteers
- 3,042 people
- Sponsor
- Yale University
STEMI, Covid19
Evaluation of the Effect of Long-term Lipid-lowering Therapy in STEMI Patients With Coronavirus Infection COVID-19
It is planned to include 200 patients hospitalized with primary myocardial infarction with and without ST segment elevation (STEMI or NSTEMI) in combination with COVID-19 within the first 15 days from the disease onset.
- Conditions
- STEMI, Covid19, NSTEMI
- Trial name
- CONTRAST-3 (NCT04900155)
- Testing
- Atorvastatin 80mg, Atorvastatin-Ezetimibe
- Where
- Russia
- Volunteers
- 45 people
- Sponsor
- Penza State University
Carotid Artery Disease, Atherosclerosis
Telerobotic Ultrasound for Carotid Imaging - Feasibility Study
In this proposal, the investigators will demonstrate the feasibility and noninferiority of telerobotic ultrasonography as compared to traditional manual acquisition in performing a limited carotid Duplex examination and in…
- Conditions
- Carotid Artery Disease, Atherosclerosis, Atheromatous Plaques, Arteriosclerosis
- Trial name
- NCT05654935
- Testing
- Ultrasound for Carotid Arteries, Telerobotic Ultrasound for Carotid Arteries
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Contrast-Induced Nephropathy, Acute Myocardial Infarction
Contrast Nephropathy Prevention With N-Acetylcysteine in Acute Myocardial Infarction
Patients with acute myocardial infarction undergoing primary angioplasty are at high risk for renal injury due to the toxic effect of contrast agents.
- Trial name
- NCT00237614
- Testing
- intravenous and oral N-acetylcysteine
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Milan
Chest Pain, Acute Coronary Syndrome
Magnetocardiography in the Accurate Identification of Myocardial Infarction
Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting myocardial infarction. Although progress has been made in this area, there is a lack of studies using up-to-date examination instruments for…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Myocardial Infarction
- Trial name
- NCT05896826
- Testing
- Magnetometer
- Where
- China
- Volunteers
- 3,841 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Myocardial Infarction, Arrhythmias
T-Wave Alternans in Acute Myocardial Infarction: An Evaluation of the Time of Testing on Its Prognostic Accuracy
T-wave alternans is an electrocardiographic finding that has been shown to predict the occurrence of future cardiac arrhythmias in patients who have had a heart attack.
- Trial name
- NCT00589849
- Testing
- T-wave Alternans
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Creighton University
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