Clinical trials: Heat Stress Disorders
Risk of Heat Stress
Impact of Pre-cooling in Adolescent Tennis Athletes
Many tennis tournaments are played outdoors in hot and humid conditions, which poses a significant challenge particularly for children athletes.
- Trial name
- NCT04197375
- Testing
- Thermal stress and performance using a pre-cooling protocol, Thermal stress and performance without a pre-cooling protocol
- Where
- Greece
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Petros Dinas
Emergence Delirium
Temperature Management on Postoperative Delirium
Presently, the effects of perioperative temperature management on postoperative delirium remain ambiguous. This study endeavors to explore the influence of intraoperative temperature variations in elderly hip fracture patients on…
- Trial name
- POD (NCT06406257)
- Testing
- 3M™ Bair Hugger™ Warming Unit
- Volunteers
- 150 people
- Sponsor
- Wang Hongjian
Heat Stroke
The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Heat Stroke
The goal of this clinical trial is to compare the effect of high chlorine solution such as normal saline and non-high chlorine solution such as sodium lactate ringer's solution on renal function in patients with heat stroke.
- Trial name
- NCT05921695
- Testing
- Normal Saline infusion and Ringer lactate infusion
- Where
- 7 sites in China
- Volunteers
- 104 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Muscle Fatigue (C23.888.592.612.612), Athletic Injuries (C26.857.500.124)
Recovery Optimization Intervention to Reduce the Risk of Injuries in Soccer Players
The goal of this clinical trial is to evaluate if recovery interventions using cold and hot water immersion can reduce the risk of injuries in amateur soccer players.
- Conditions
- Muscle Fatigue (C23.888.592.612.612), Athletic Injuries (C26.857.500.124), Recovery of Function (G11.427.698.620), Cryotherapy (E02.095.301.250)
- Trial name
- NCT06920966
- Testing
- Cold Water Immersion (CWI), Hot water immersion (HWI), Thermography-Guided Immersion (TI)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Head and Neck Cancer, Oropharyngeal Carcinoma
Thermotherapy for Locally Advanced Head and Neck Cancer
Patients with head and neck cancer treated with radiotherapy (RT) have a substantial change of recurrence of the tumor in the pharynx or lymph nodes in the neck. Once tumor and/or lymph nodes have recurred, the prognosis is poor.
- Conditions
- Head and Neck Cancer, Oropharyngeal Carcinoma, Hypopharyngeal Carcinoma, Laryngeal Cancer
- Trial name
- TANCA-I (NCT06761937)
- Testing
- Thermotherapy, radiotherapy
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- Erasmus Medical Center
Healthy
BHB and Cognition During Exercise-Heat Stress
The study investigates how consuming a ketone ester (BHB) along with caffeine impacts cognitive performance under heat stress, similar to what military personnel experience in hot environments.
- Trial name
- NCT07010666
- Testing
- Beta-Hydroxybutyrate, Carbohydrate, Caffeine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Type 2 Diabetes
Heat Therapy and Strength Training Effects in Individuals With Type 2 Diabetes
The aim of this study is to compare different non-pharmacological interventions in Type 2 diabetic people, testing their efficiency to improve metabolism and inflammation.
- Trial name
- NCT05847075
- Testing
- Heat Therapy, StrengthTraining, Sedentary Control
- Where
- 2 sites in Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of Rio Grande do Sul
Body Temperature Changes
Cooling Vest May Reduce Heat Stress During Surgery
The investigators will propose a randomized cross-over trial using a uniform and strongly balanced 4-period design in which will include four operations for each surgeon.
- Trial name
- NCT04511208
- Testing
- Cooling Vest, Without cooling vest
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Fatigue
Bundling and Unbundling the Laparoscopic Electrosurgery Cord With the Camera Cord
Electrosurgery is used in virtually every laparoscopic operation performed. Capacitive coupling is a common electrosurgery complication.
- Trial name
- NCT01707095
- Testing
- Unbundling of cords, Bundling of cords
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Warts
Randomized Controlled Clinical Trial of Hyperthermia and Hydrogen Peroxide 3% in the Treatment of Cutaneous Warts
Hyperthermia treatment (hyperthermia) refers to treating diseases with temperature (39-45 ° C) beyond normal body temperature,. It has been reported that local warming at 44 ° C is able to effectively mobilize the body's immunity…
- Trial name
- NCT06812065
- Testing
- Hydrogen Peroxide 3 % Topical Solution, Local Hyperthermia at 44℃
- Where
- 2 sites in China
- Volunteers
- 300 people
- Sponsor
- First Hospital of China Medical University
Hyperthermia, Thermoregulation
Enhancing Heat Resiliency in Older Adults During Indoor Overheating Via Heat Acclimation by Warm Water Immersion
As overheating in buildings is expected to increase as global warming continues, proactive measures to increase heat resiliency in heat-vulnerable older people are needed, especially for those without access to home cooling or…
- Conditions
- Hyperthermia, Thermoregulation, Aging, Heat Acclimation and Thermotolerance
- Trial name
- NCT06670365
- Testing
- Heat acclimation by warm-water immersion
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Hyperthermia
Dantrolene for Treatment of Hyperthermia in Subarachnoidal Hemorrhage (SAH)
Dantrolene is used to prevent hyperthermia in intensive care patients suffering from subarachnoidal hemorrhage.
- Trial name
- DTH1 (NCT00796900)
- Testing
- Dantrolene
- Where
- Austria
- Volunteers
- 34 people
- Sponsor
- Medical University of Vienna
Hyperthermia, Cardiac Functional Disturbances During Surgery
Effect of Heat Stress on Global LV Function in Anesthetized Humans
Recent data suggests that increased temperature improves inotropic function during systole and may improve diastolic function in healthy humans at rest, despite a reduction in left ventricular volume at end diastole.
- Trial name
- NCT04553900
- Testing
- Transesophageal Echocardiography
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Diego
Postpartum Hemorrhage
Treatment of Postpartum Hemorrhage With Misoprostol: Fever Study
This study seeks to assess whether populations of women in Latin America outside Quito, Ecuador are at increased risk for developing elevated body temperature above 40.0°C following PPH treatment with 800mcg sublingual…
- Trial name
- NCT02163616
- Testing
- Misoprostol
- Where
- 2 sites in Argentina
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Fever
Tympanic Thermometers Accuracy
The aim of the present study is to evaluate the measurement precision and accuracy of the third-generation tympanic thermometer in relation to the measurement modalities considered gold standard.
- Trial name
- NCT06103604
- Testing
- latest generation tympanic thermometer
- Where
- 7 sites in Italy
- Volunteers
- 1,100 people
- Sponsor
- Istituto Ortopedico Rizzoli
Inguinal Hernia
Electrocoagulation Employment During TAPP Inguinal Hernia Repair
Laparoscopic TAPP (transabdominal preperitoneal) hernia repair presents a minimally invasive surgical procedure, which tends to be a gold standard in a wide range of inguinal hernia operations.
- Trial name
- NCT03566784
- Testing
- Inguinal hernia repair
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Aging, Heat Stress
Physiological Responses in Young and Older Adults During a Prolonged Simulated Heatwave
Climate change not only affects the planet's natural resources, but also severely impacts human health. An individual's ability to adequately cope with short- or long-term increases in ambient temperature is critical for…
- Conditions
- Aging, Heat Stress, Physiological Stress
- Trial name
- HW1 (NCT04353076)
- Testing
- Simulated heatwave exposure, Simulated heatwave exposure with mid-day cooling
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Circumcision
Bipolar Electrosurgery Versus Thermocautery in Circumcision With Safe Anesthetic Techniques
Background: Circumcision is the most commonly performed surgical procedure done among the pediatric age group worldwide and is considered to be one of the oldest operations done.
- Trial name
- NCT05590052
- Testing
- Bipolar Electrosurgery, Thermocautery
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Damanhour Teaching Hospital
Metastatic Breast Cancer, Breast Cancer
Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer
In this phase I feasibility study, the investigators evaluate the combination of lyso-thermosensitive liposomal doxorubicin (LTLD, ThermoDox) with local hyperthermia and cyclophosphamide (C), for the local treatment of the…
- Conditions
- Metastatic Breast Cancer, Breast Cancer, Breast Neoplasms, Stage IV Breast Cancer
- Trial name
- i-GO (NCT03749850)
- Testing
- LTLD, MR-HIFU induced hyperthermia, Cyclophosphamide
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- UMC Utrecht
Heat Stress, Athletic Performance
Effectiveness of Topical Menthol as A Cooling Method During Exercise in A Recreational Runner Population
The goal of this clinical trial is to evaluate the effectiveness of topical menthol as a cooling method during exercise in a hot air environment in healthy adult recreational runners aged 18 to 45 years.
- Trial name
- NCT07482046
- Testing
- Light blue gel with the trademark Counterpain COOL® (License Number: POM QD. 111 709 501) containing the active substance Menthol 4%.
- Where
- Indonesia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Taisho Pharmaceutical Indonesia