Clinical trials: Heathy Volunteer
Bioavailability Heathy Volunteers, Safety
Pharmacokinetics and Safety of a New Micellar Glutathione Formulation
This study seeks to determine the short-term effects of daily oral supplementation with a new micellar Glutathione formulation (LipoMicel) on the oral absorption and safety of glutathione in healthy volunteers.
- Trial name
- NCT06345950
- Testing
- Liposomal Glutathione, Standard Glutathione, New Micellar Glutathione (Lipomicel)
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Factors Group of Nutritional Companies Inc.
COVID-19
A Clinical Trial to Assess the Safety and Immunogenicity of Nanocovax in Heathy Volunteers
The purpose of this study is to assess the safety, tolerability, and immunization of Nanocovax in healthy volunteers.
- Trial name
- NCT04683484
- Testing
- Nanocovax
- Where
- Vietnam
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Nanogen Pharmaceutical Biotechnology Joint Stock Company
Bioavailability Heathy Volunteers, Bioavailability Study
Bioavailability of Trazodone Hydrochloride (New Polymer) vs. Trazodone Hydrochloride Contramid® at Steady-state.
Two way, two parallel groups, crossover study to compare the bioavailability of 150 mg and 300 mg trazodone hydrochloride (new polymer) (Angelini Pharma S.p.A.) vs.
- Conditions
- Bioavailability Heathy Volunteers, Bioavailability Study, Bioequivalance
- Trial name
- NCT06773767
- Testing
- 150 mg trazodone hydrochloride, 300 mg trazodone hydrochloride
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Bioavailability Heathy Volunteers
Bioavailability and Bioequivalence Study of Extended Release Torsemide and Spironolactone
To study intrasubject variability and steady-state pharmacokinetics of multiple-doses of Extended Release Torsemide and Spironolactone Fixed Dose Combination (FDC) tablets given together in healthy adult subjects.
- Trial name
- NCT07046975
- Testing
- Torsemide and Spironolactone tablet, Torsemide Tablets and Spironolactone Tablets
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sarfez Pharmaceuticals, Inc.
Drug-Drug Interaction, Heathy Volunteer
Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity
Primary objective: 1. To assess the potential inhibitory and inducing effect of oral givinostat on the single dose pharmacokinetics (PK) of intravenous or oral midazolam. 2.
- Trial name
- NCT05492318
- Testing
- Givinostat 10 mg/mL, Midazolam 1mg/ml IV, Midazolam 2.5 mg oromucosal solution
- Where
- Portugal
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Italfarmaco
Heathy Volunteer
A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult Subjects
This is a four-part study to evaluate the effect of multiple doses of CC-90001 on the PK, safety, and tolerability of single doses of omeprazole, midazolam, warfarin, rosuvastatin, metformin, digoxin, and nintedanib in healthy…
- Trial name
- NCT03363815
- Testing
- CC-90001, Omeprazole, Midazolam
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Celgene
Pharmacokinetic Parameters, Bioavailability Heathy Volunteers
A Clinical Trial to Assess the Pharmacokinetic Profile of Three Coenzyme Q10 Formulations in Healthy Adults
The goal of this clinical trial is to assess the pharmacokinetic profile of three Coenzyme Q10 formulations in healthy adults. The main question it aims to answer is: What is the difference in the bioavailability of three…
- Trial name
- NCT07255079
- Testing
- VitaDry-Q10, VitaSperse-Q10, Coenzyme Q10
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- 3i Solutions
Healthy Subjects
Stools and Life Habits Collection in Heathy Volunteers/Subjects - to Provide Material for in Vitro Model Development
The purpose of this clinical study is to collect well characterized stools from healthy adult subjects, with completed life habits and alimentary questionnaires.
- Trial name
- PEPSIIN (NCT04301973)
- Testing
- Stool collection
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Bioavailability Heathy Volunteers
A Study to Evaluate the Effect of Food or no Food on the Bioavailability of an Extended Release (ER) Torsemide and Spironolactone Fixed Dose Combination (FDC) Tablet in Healthy Adult Subjects
This study will examine comparative bioavailability of single dose of a fixed dose combination (FDC) of extended release Torsemide and Spironolactone given with or without food in healthy adult subjects.
- Trial name
- NCT07043634
- Testing
- FDC (24 mg ER torsemide and 30 mg Spironolactone) without food, FDC (24 mg ER torsemide and 30 mg Spironolactone) with food
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sarfez Pharmaceuticals, Inc.
Bioavailability Heathy Volunteers
Study to Investigate if the Uptake of Ticagrelor Into the Body Differs Depending on Method of Administration.
Study to investigate if the uptake of Ticagrelor into the body differs depending on method of administration.
- Trial name
- NCT01887626
- Testing
- Ticagrelor 90 mg whole tablet, Ticagrelor 90 mg tablet crushed, Dispersed ticagrelor 90 mg tablet suspended in water - nasogastric tube
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Heathy Volunteer
Food-effect on PK and PD of Single Oral Dose of HIP1601 in Healthy Male Subjects
Primary objective To evaluate food effect on the pharmacokinetics (PK) of a single oral dose of HIP1601 in healthy subjects under fed or fasting condition.
- Trial name
- NCT03882112
- Testing
- HIP1601 40mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Heathy Volunteers
Bioequivalence Study Comparing Single Dose of Ferrinemia® Injection With a Single Dose of Venofer® Injection in Healthy Male Volunteers
The aim of this pharmacokinetic study is to assess the bioequivalence of the generic Ferrinemia® Iron Sucrose injection solution 20 mg/mL manufactured by Help S.A., Greece (test product), to Venofer® Iron Sucrose injection…
- Trial name
- NCT03093883
- Testing
- Ferrinemia, Venofer
- Where
- Austria
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Azad Pharma AG