Clinical trials: Heathy Volunteer

Drug-Drug Interaction, Heathy Volunteer

Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity

• Completed
• Age: 18 to 55 years
• Phase 1
• Pill or oral medicine
• Injection or infusion
• Results posted

Primary objective: 1. To assess the potential inhibitory and inducing effect of oral givinostat on the single dose pharmacokinetics (PK) of intravenous or oral midazolam. 2.

Trial name

NCT05492318

Testing

Givinostat 10 mg/mL, Midazolam 1mg/ml IV, Midazolam 2.5 mg oromucosal solution

Where

Portugal

Volunteers

26 people, healthy volunteers welcome

Sponsor

Italfarmaco