Clinical trials: Helicobacter
Helicobacter Infections
Efficacy on Helicobacter Pylori Eradication With Two Antibiotic Regimens
Clinical trial to compare efficacy on eradicating Helicobacter pylori with two antibiotic strategies: sequential with amoxicillin and omeprazole 5 days and clarithromycin with metronidazole and omeprazole 5 days or omeprazole…
- Trial name
- NCT02395458
- Testing
- Sequential therapy, Triple therapy
- Volunteers
- 142 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Helicobacter Pylori Infection
Stool Antigen In Diagnosis Of Helicobacter Pylori
Helicobacter pylori is among the most common bacterial infections in humans. Helicobacter pylori is a Gram-negative, S -shaped rod .The most likely mode of transmission is fecal-oral or oral-oral.
- Trial name
- NCT05802732
- Testing
- Stool Antigen test
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
Traditional Chinese Medicine Combined With Standard Triple Region for Eradication of Helicobacter Pylori
To evaluate the efficacy and safety of Traditional Chinese Medicine (TCM) decoction and powder combined with standard triple therapy on improving eradication rate of Helicobacter Pylori (H.
- Trial name
- NCT02803216
- Testing
- standard triple region, 2-week Xiang-sha-liu-jun decoction, 4-week Xiang-sha-liu-jun decoction
- Volunteers
- 576 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Helicobacter Pylori Infection
The Study About the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure
The patients who accepted the quadruple eradication program of the helicobacter pylori but failed to eradicate helicobacter pylori will be assessed the most suitable re-eradication time of helicobacter pylori.
- Trial name
- NCT05173493
- Testing
- Amoxicillin,Furazolidone, Amoxicillin,Levofloxacin, Tetracycline,Furazolidone
- Where
- China
- Volunteers
- 670 people
- Sponsor
- Shandong University
Helicobacter
Efficacy of Probiotics in the Gut Microbiota and H Pylori Density
We aimed to assess the efficacy of Lactobacillus acidophilus and Lactobacillus rhamnosus in the reduction of bacterial load of H.
- Trial name
- NCT02725138
- Testing
- Probiotic
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Statistical Center, NTUHCTC
Helicobacter Pylori Infection
Prevalence and Risk Factors of Helicobacter Pylori Infection in Children and Young Adults
Helicobacter pylori is a gram-negative bacterium that resides in the stomach and can cause inflammation leading to long-term effects, such as gastric ulcers, cancer, and lymphoma of the stomach mucosal linings Previous research…
- Trial name
- NCT05830357
- Where
- Egypt
- Volunteers
- 667 people
- Sponsor
- Sohag University
Autoimmune Diseases, Helicobacter Pylori Gastritis
Pyloric or Pseudopyloric Metaplasia of the Corpus Mucosa in Autoimmune Gastritis
The study is aimed to investigate the different rates of pyloric/ pseudopyloric metaplasia or spasmolytic polypeptide-expressing metaplasia (SPEM) of corpus between autoimmune gastritis and H. pylori-infected non-ulcer dyspepsia.
- Conditions
- Autoimmune Diseases, Helicobacter Pylori Gastritis, Anemia, Pernicious, Metaplasia
- Trial name
- PM_in_AIG (NCT05238181)
- Testing
- Assess pyloric or pseudopyloric metaplasia of corpus by H&E stains, Assess pyloric or pseudopyloric metaplasia of corpus by TFF2 immunohistochemistry stains, The assessment of corpus-predominant gastritis index (CGI), Operative Link for Gastritis Assessment (OLGA), and Operative Link on Gastric Intestinal Metaplasia assessment (OLGIM)
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Cheng-Kung University Hospital
Helicobacter Pylori Infection, Gastric Ulcer
A Study on the Gastrointestinal Disease and Helicobacter Pylori Controlled Long Non-coding RNA
Helicobacter pylori (H.pylori) is a major human pathogenic bacterium in gastric mucosa which is linked to the development of gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue lymphoma and gastric cancer.
- Conditions
- Helicobacter Pylori Infection, Gastric Ulcer, Duodenal Ulcer, Stomach Cancer
- Trial name
- NCT03057171
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Functional Dyspepsia
Helicobacter Eradication Relief of Dyspeptic Symptoms
A double-blind clinical trial investigating if a sub-group of functional dyspeptic patients without any use of NSAID or gastric erosions could have a better evolution of their dyspeptic symptoms after Helicobacter eradication…
- Trial name
- HEROES-12 (NCT00404534)
- Testing
- Amoxicillin, Clarythromycin, Omeprazole for ten days
- Where
- Brazil
- Volunteers
- 407 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Helicobacter Infections
The Effect of Probiotic Combination on Helicobacter Pylori Infection in Children
The combination of two Lactubacillus reuteri strains, ATC 55730 and ATCC PTA 6457 are marketed as GASTRUS® and has been proposed as better option in increasing Helicobacter pylori eradication rate compared to the single strain…
- Trial name
- Gastrus (NCT02645201)
- Testing
- Gastrus
- Where
- 5 sites in Belgium, Croatia and 3 more
- Sponsor
- University Medical Centre Ljubljana
Self Efficacy
Genotypic Resistance Guided Therapy in Helicobacter Pylori Eradication
We aimed to compare the efficacy of genotypic resistance guided sequential therapy vs. empiric therapy in the third line therapy.
- Trial name
- NCT01725906
- Testing
- empirical therapy, Genotypic resistance guided therapy
- Where
- 2 sites in Taiwan
- Volunteers
- 450 people
- Sponsor
- National Taiwan University Hospital
Helicobacter Pylori Infection, Iron Deficiency Anemia
Is Helicobacter Pylori Infection a Cause or Treatment Failure of Iron Deficiency Anemia in Children in Bangladesh?
Helicobacter pylori is recognized as a major gastrointestinal pathogen in developing countries. This microorganism infects up to 60% of children less than five years in those countries and is strongly associated with chronic…
- Conditions
- Helicobacter Pylori Infection, Iron Deficiency Anemia, Not Severely Malnourished, No Systemic Infection
- Trial name
- NCT00284700
- Testing
- Iron
- Where
- Bangladesh
- Volunteers
- 260 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Cystic Fibrosis, Abdominal Pain
An Investigation of the Association Between Helicobacter Pylori Infection and Abdominal Pain in Cystic Fibrosis Patients
Cystic fibrosis (CF) is the most common lethal autosomal recessive disease among Caucasians. While the pulmonary disease in CF receives most of the attention, gastrointestinal diseases occur in >95% of CF individuals and can…
- Conditions
- Cystic Fibrosis, Abdominal Pain, Helicobacter Pylori Infection
- Trial name
- NCT00765401
- Where
- United States
- Sponsor
- Penn State University
Helicobacter Pylori Infection
Helicobacter Pylori Eradication and Follow-up
This randomized controlled clinical trial will estimate the eradication efficacy of different therapy for Helicobacter pylori treatment.
- Trial name
- NCT05061732
- Testing
- Rabeprazole, Bismuth potassium citrate, Metronidazole
- Where
- China
- Volunteers
- 4,447 people
- Sponsor
- Shanghai Zhongshan Hospital
Helicobacter Pylori Infection, Chronic Gastritis
Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.
The aim of this study is to evaluate the efficacy and safety of a quadruple therapy consisting of berberine hydrochloride, minocycline, esomeprazole, and colloidal bismuth tartrate for the first phase eradication of Helicobacter…
- Trial name
- NCT06603688
- Testing
- esomeprazole, Bismuth, Amoxicillin
- Where
- China
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
MALT Lymphoma
Eradication of Helicobacter Pylori in the Management of Stage IE & IIE-1 Primary Low-grade B Cell Lymphoma of MALToma
To evaluate the therapeutic effectiveness of H. pylori eradication in stage IE \& IIE-1 primary low-grade B cell lymphoma of MALT of the stomach
- Trial name
- NCT00201422
- Testing
- Omeprazole, Amoxicillin, Clarithromycin
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Health Research Institutes, Taiwan
HELICOBACTER PYLORI INFECTIONS
Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection
this Study Evaluating Safety and Effectiveness of (Proton Pump Inhibitor versus Vonoprazan) Based Triple Therapy with or without Zinc to Eradicate H. pylori Infection
- Trial name
- NCT07275827
- Testing
- zinc sulfate, Vonoprazan + amoxicillin + clarithromycin, proton pump inhibitor + amoxicillin
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Tanta University
Pancreatitis, Acute, Helicobacter Infections
Helicobacter Pylori and Acute Alcohol Induced Pancreatitis
This study is performed to measure wether Helicobacter Pylori has an effect on the incidence and course of acute alcohol induced pancreatitis
- Trial name
- NCT00490386
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Tampere University
Helicobacter Pylori, Gastritis
Safety and Immunogenicity of Chiron's Investigational H. Pylori Vaccine in Healthy Adults
This study was designed to investigate the safety and immunogenicity of Chiron's investigational H. pylori (HP3) vaccine
- Conditions
- Helicobacter Pylori, Gastritis, Gastric Cancer, Gastroduodenal Ulcers
- Trial name
- NCT00613665
- Testing
- helicobacter pylori vaccine
- Where
- Germany
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Parkinson's Disease, Helicobacter Infections
Treating H. Pylori in Parkinson's Patients With Motor Fluctuations
The purpose of this study is to determine whether treatment of H. pylori (an infection of the stomach) improves treatment effectiveness in patients with Parkinson's disease and motor fluctuations.
- Conditions
- Parkinson's Disease, Helicobacter Infections, Motor Fluctuations
- Trial name
- NCT00664209
- Testing
- clartihromycin, amoxicillin, and omeprazole
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of California, Los Angeles