Clinical trials: Helicobacter
Helicobacter Pylori Infection
Tetracycline Versus Doxycycline for HP Rescue Therapy
This randomized controlled clinical trial will evaluate the efficacy and safety of proton pump inhibitor, bismuth, metronidazole, and either tetracycline or doxycycline for Helicobacter pylori rescue treatment.
- Trial name
- NCT05018923
- Testing
- Rabeprazole, Bismuth potassium citrate, Metronidazole
- Where
- China
- Volunteers
- 242 people
- Sponsor
- Shanghai Zhongshan Hospital
H Pylori Infection
HELICOBACTER PYLORI INFECTION IN TYPE 2 DIABETES MELLITUS IN ASSIUT UNIVERSITY HOSPITAL
The aim is to study the association of H. pylori infection with T2DM and its relation with glycated hemoglobin (HbA1c) levels
- Trial name
- NCT05789550
- Testing
- ALL PATIENT DIABETIC IN THIS PERIOD WILL BE INCLUDED IN THE STUDY
- Volunteers
- 146 people
- Sponsor
- Assiut University
Helicobacter Infections, Gastritis
Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori)
Helicobacter pylori (Hp) is a major cause of chronic-active gastritis and primary duodenal ulcers, and is strongly linked to gastric cancer. Most Hp infections worldwide are acquired in childhood.
- Conditions
- Helicobacter Infections, Gastritis, Peptic Ulcer
- Trial name
- NCT00212225
- Where
- 3 sites in United States
- Volunteers
- 755 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Helicobacter Pylori Infection
Fecal Molecular Susceptibility-guided Hp Rescue Therapy
The goal of this clinical trial is to evaluate the eradication efficacy and health economic benefits of individualized regimens guided by fecal molecular susceptibility testing with 7-day and 14-day courses in the rescue…
- Trial name
- NCT07405697
- Testing
- 7-day fecal molecular susceptibility-guided therapy, 14-day fecal molecular susceptibility-guided therapy
- Where
- 4 sites in China
- Volunteers
- 290 people
- Sponsor
- Shanghai Zhongshan Hospital
Gastric Cancer, Precancerous Lesion
Nasal Endoscopic Screening and Risk Assessment for Early Gastric Cancer
Pepsinogens (PGs) can be used for gastric cancer (GC) screening, but the cutoff levels vary among studies, and PG levels are influenced by numerous factors.
- Conditions
- Gastric Cancer, Precancerous Lesion, Helicobacter Pylori Infection
- Trial name
- NCT04989153
- Testing
- pepsinogen
- Where
- 9 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Helicobacter Pylori Infection
Helicobacter Pylori and Lacidophilin Tablets in Combination With Vonorazan Dual Therapy
Our previous study included 119 Helicobacter pylori(H. pylori)-infected Chinese patients without previous eradication history who were randomized to low-or high-dose amoxicillin-vonoprazan regimens consisting of amoxicillin 1…
- Trial name
- NCT05749081
- Testing
- Lacidophilin tablets in combination with vonorazan dual therapy
- Where
- China
- Volunteers
- 324 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
H. Pylori Infection
Oral Helicobacter Pylori Eradication
Helicobacter pylori (H. pylori) is a serious health threat that infects approximately half of the global population. In addition to colonizing the stomach, H.
- Trial name
- NCT06045832
- Testing
- MAXPOWER Biological Antibacterial Liquid, Water
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Changhai Hospital
Helicobacter Pylori
Helicobacter in The Gambia (Part 1)
H. pylori infection causes the stomach to become inflamed. The problem usually begins in childhood and leads to stomach problems in adult life.
- Trial name
- NCT00466700
- Where
- The Gambia
- Volunteers
- 75 people
- Sponsor
- Medical Research Council Unit, The Gambia
GASTRITIS
Levofloxacin-Doxycycline for Helicobacter Pylori Eradication in Saudi Arabia
Helicobacter pylori (H. pylori) eradication is achieved in 60-80% with first-line therapy. Different second-line therapeutic options are available.
- Trial name
- NCT02884713
- Testing
- Levofloxacin, Doxycycline, Esomeprazole
- Volunteers
- 55 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Helicobacter Pylori Infection
Banxiaxiexin Decoction Combined With Vonoprazan-Amoxicillin Dual Therapy in H. Pylori Eradication
Vonoprazan and high-dose amoxicillin dual therapy was used as a control group to evaluate the clinical efficiency and safety of Banxiaxiexin decoction combined with vonoprazan and high-dose amoxicillin dual therapy in the…
- Trial name
- NCT06340724
- Testing
- Vonoprazan, Amoxicillin, Banxiaxiexin decoction
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Gastric Cancer, Cancer Prevention
Personalised Health Recommendations to the General Population Through an Integrated AI Guided
This clinical study aims to be used to implement and validate the AIDA tool in two phases: Phase 1: Risk stratification and personalised recommendations \& Model development Phase 2: Mechanistic Model (Bioresource) development \&…
- Conditions
- Gastric Cancer, Cancer Prevention, Helicobacter Pylori Infection, Artificial Intelligence
- Trial name
- AIDA (NCT06421324)
- Testing
- Health reccommendations
- Where
- Spain
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Helicobacter Pylori Infection
The Effect of Broccoli Sprout Extract and Probiotics for Eradication of Helicobacter Pylori
In Korea, the first-line therapy to treat Helicobacter pylori (Hp) consists of a proton pump inhibitor (PPI) and two antibiotics for one week.
- Trial name
- NCT03220542
- Testing
- Probiotics, Broccoli, Esomeprazole
- Where
- South Korea
- Volunteers
- 360 people
- Sponsor
- Kyunghee University Medical Center
H. Pylori Infection
A Comparative Study Between Concomitant Versus Load Therapy in Eradication of Helicobacter Pylori Infection
All patients who presented with epigastric pain and dyspeptic symptoms will undergo endoscopic gastric biopsies. The patients will be subjected to: Full history taking, clinical examination, liver function tests, renal function…
- Trial name
- NCT06050824
- Testing
- Comparing Load and Concomitant therapy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Helwan University
Duodenal Ulcer
Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Duodenal Ulcer Participants With or Without Helicobacter Pylori Infection
The purpose of this study is to demonstrate the non-inferior efficacy of TAK-438 versus lansoprazole in the treatment of participants with duodenal ulcer.
- Trial name
- NCT03050359
- Testing
- TAK-438, Lansoprazole, Bismuth-Containing Quadruple Therapy
- Where
- 81 sites in China, Philippines and 2 more
- Volunteers
- 533 people
- Sponsor
- Takeda
Dyspepsia, Helicobacter Pylori Infection
Helicobacter Pylori Eradication in Functional Dyspepsia
This study is designed to study benefit of eradicating Helicobacter Pylori in patients with functional dyspepsia as compared to symptomatic treatment only.
- Trial name
- NCT04697641
- Testing
- Clarithromycin 500mg, Amoxicillin 1000 MG, Pantoprazole 40mg
- Where
- India
- Volunteers
- 202 people
- Sponsor
- Sir Ganga Ram Hospital
Helicobacter Pylori Eradication
14-day PCAB-based High-dose Dual Therapy and14-day PCAB-based Triple Therapy vs 14-day PPI-based Reverse Hybrid Therapy
1. Test for Helicobacter pylori. The test items include urease test, histology, bacterial culture, serology, and urea breath test. At least two positive results can be used to confirm the diagnosis. 2.
- Trial name
- NCT05191888
- Testing
- Vonoprazan and Amoxicillin, Vonoprazan, Amoxicillin and Clarithromycin, Rabeprazole, Amoxicillin, Clarithromycin and Metronidazole
- Where
- Taiwan
- Volunteers
- 906 people
- Sponsor
- Kaohsiung Medical University
H. Pylori Infection
Efficacy of Vonoprazan Based Dual and Triple Therapy for Patient With Helicobacter Pylori Infection
This study aims to assess Efficacy of vonoprazan based dual and triple therapy for naïve patient with Helicopacter Pylori infection in Sohag Government .
- Trial name
- NCT07045688
- Testing
- Efficacy of Vonoprazan based dual therapy for naive patient with Helicobacter Pylori infection, Efficacy of Vonoprazan based triple therapy for naive patient with Helicobacter Pylori infection, Efficacy of PPI based triple therapy for naive patient with Helicobacter Pylori infection
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Helicobacter Pylori Infection, Renal Transplant Infection
Helicobacter Pylori Infection in Renal Transplant Patients
Upper gastrointestinal (GI) symptoms are frequent in organ transplant recipients. Peptic ulcers and related pathologies such as gastritis and duodenitis are known to occur with increased frequency (20-60%) and severity in renal…
- Trial name
- NCT03310255
- Testing
- H pylori Faecal Antigen
- Volunteers
- 86 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
Urea Breath Test (UBT) With Breath Hp System /BreathID Hp Lab System Pediatrics
Clinical Study to Confirm Safety and Accuracy in Detection of H. pylori with 13C-Urea Breath Test using the BreathID® Hp and BreathID® Hp Lab Systems in the Pediatric Population
- Trial name
- NCT02905825
- Testing
- BreathID® Hp System, BreathID® Hp Lab System, Stool Test
- Where
- 6 sites in United States, Israel
- Volunteers
- 54 people
- Sponsor
- Meridian Bioscience, Inc.
Helicobacter Pylori Infection
Comparison of Helicobacter Pylori Eradication Effect Before and After Training of Gastroenterologists
The researchers recruited gastroenterologists. Physician subjects recruited Helicobacter pylori-positive patients before and after receiving standardized training on Helicobacter pylori eradication.
- Trial name
- NCT05065138
- Testing
- Standardized training on Helicobacter pylori eradication treatment
- Where
- China
- Volunteers
- 1,025 people, healthy volunteers welcome
- Sponsor
- Shandong University