Clinical trials: Helicobacter
MALT Lymphoma
Eradication of Helicobacter Pylori in the Management of Stage IE & IIE-1 Primary Low-grade B Cell Lymphoma of MALToma
To evaluate the therapeutic effectiveness of H. pylori eradication in stage IE \& IIE-1 primary low-grade B cell lymphoma of MALT of the stomach
- Trial name
- NCT00201422
- Testing
- Omeprazole, Amoxicillin, Clarithromycin
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Health Research Institutes, Taiwan
Helicobacter Pylori
A Study of Vonoprazan in Adults With Helicobacter Pylori
Helicobacter Pylori (H Pylori) is a bug found in the digestive system. It can cause soreness and redness in the stomach (gastritis). It can also cause ulcers in the stomach and other parts of the digestive system.
- Trial name
- NCT04753437
- Testing
- Clarithromycin, Amoxicillin, Bismuth potassium citrate
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Takeda
Helicobacter Pylori Eradication Rate
Vonoprazan Fumarate in Combination With Amoxicillin for the First-line Eradication of Helicobacter Pylori -- a Multicenter, Randomized, Parallel Controlled Study
Helicobacter pylori infection is closely related to gastritis, peptic ulcer, mucosa-associated lymphoid tissue lymphoma and gastric cancer. Eradication of HP can significantly improve and reduce HP-related diseases.
- Trial name
- NCT05196945
- Testing
- vonoprazan fumarate + amoxicillin, Esomeprazole +Amoxicillin+Clarithromycin+Bismuth potassium citrate
- Volunteers
- 316 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Helicobacter Pylori Infection, Dyspepsia
Effect of H. Pylori Eradication on The Improvement of Gastrointestinal Symptoms
This study aims to evaluate the effect of Helicobacter pylori eradication on gastrointestinal symptoms in adult patients. H. pylori infection is a common cause of dyspepsia and other upper gastrointestinal complaints.
- Conditions
- Helicobacter Pylori Infection, Dyspepsia, Gastrointestinal Symptoms
- Trial name
- HPE-GI (NCT07272681)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amany Usama Ahmed Arafa
HIV, Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
The Impact of Helicobacter Pylori Infection on Immune Regulation and Clinical Course in HIV Patients in Ghana
The main objective of the study is to investigate the impact of H. pylori infection on immune activation and clinical outcome in HIV patients. Other specific study objectives are: 1. To investigate the effects of H.
- Trial name
- HHECO (NCT01897909)
- Where
- Ghana
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Bernhard Nocht Institute for Tropical Medicine
Helicobacter Pylori Infection
Intraluminal Amoxicillin Powder Monotherapy for Helicobacter Pylori Infection
Helicobacter pylori (H. pylori) is the most common chronic bacterial infection in humans. The prevalence of H. pylori is about 30~50% in the Western adult population.
- Trial name
- NCT03521726
- Testing
- Amoxicillin, Rabeprazole, Amoxicillin
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Mackay Memorial Hospital
Helicobacter Pylori Infection
Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Therapy of Different Tetracycline Doses and Frequencies.
The researchers collect H.pylori-positive patients who need rescue therapy from the outpatient clinic. The subjects were randomized to receive a dose and frequency of tetracycline 500mg tid or qid of bismuth quadruple eradication…
- Trial name
- NCT05432115
- Testing
- Tetracyclin
- Where
- China
- Volunteers
- 407 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection
The Impact of Antibiotics MIC Value on the Efficacy of Treatment Regimens for Helicobacter Pylori Infection.
Clarithromycin (CLA)、amoxicillin (AMO)、metronidazole (MET)、levofloxacin (LEV) and tetracycline (TET) are commonly used antibiotics for Helicobacter pylori (Hp) therapy.
- Trial name
- NCT03583476
- Testing
- Proton pump inhibitor,clarithromycin,amoxicillin or metronidazole
- Where
- Taiwan
- Volunteers
- 1,821 people
- Sponsor
- National Taiwan University Hospital
H. Pylori Infection
Efficacy Analysis of Saccharomyces Boulardii Combined With Minocycline in Treatment-naïve Patients With Helicobacter Pylori Infection
To assess the efficacy and safety of Saccharomyces boulardii combined with triple therapy containing minocycline in the initial eradication of Helicobacter pylori (H. pylori) infection
- Trial name
- NCT07012785
- Testing
- Bismuth quadruple therapy, Saccharomyces boulardii
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Zhongda Hospital
Helicobacter Pylori Infection
Low Dose Bismuth Versus Lactobacillus Reuteri for H. Pylori Eradication
This study investigates the efficacy of a b.i.d. quadruple therapy containing Pylera® or L. reuteri for H. pylori infection.
- Trial name
- LactoBismu (NCT03925818)
- Testing
- Bismuth Subcitrate Potassium, Gastrus
- Where
- Italy
- Volunteers
- 99 people
- Sponsor
- Università degli Studi di Sassari
Functional Dyspepsia
New Dual Therapy for Primary Treatment of Helicobacter Pylori Infection：a Pilot Study
The efficacy of traditional triple therapy has been decreased to such an unacceptable level as 70% in many areas. The study is based on the hypothesis: the most important factors which influence the effect of Helicobacter pylori…
- Trial name
- NCT01513785
- Testing
- Rabeprazole and Amoxicillin, Amoxicillin and Rabeprazole
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Gastric Atrophy, Gastric Cancer
Epidemiology of Helicobacter Pylori Infection in Moscow
H. pylori is transmitted from individual to individual and causes chronic active gastritis in all infected people. H. pylori infection can result in gastroduodenal ulcers, atrophic gastritis (AG), gastric carcinoma, and gastric…
- Conditions
- Gastric Atrophy, Gastric Cancer, Helicobacter Pylori Infection
- Trial name
- NCT05775120
- Testing
- OLGA and H.pylori culture
- Where
- Russia
- Volunteers
- 5,121 people, healthy volunteers welcome
- Sponsor
- Moscow Clinical Scientific Center
Healthy
To Investigate Pharmacokinetics and Pharmacodynamics of CJ-12420 After Single and Multiple Dose Administration
The purpose of this study is to compare the pharmacokinetics and pharmacodynamics of CJ-12420 after single and multiple dose administration according to H. pylori infection.
- Trial name
- NCT03009760
- Testing
- CJ-12420 50mg(HP-), CJ-12420 100mg(HP-), CJ-12420 50mg(HP+)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
MALT Lymphoma
Trial of Lenalidomide in Patients With Lymphoma of the Mucosa Associated Lymphoid Tissue (MALT) Type
The activity of monotherapy with Lenalidomide will be evaluated in patients with lymphoma of the mucosa associated lymphoid tissue (MALT).
- Trial name
- NCT00923663
- Testing
- Lenalidomide
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Medical University of Vienna
Helicobacter Pylori
Vonoprazan-Based Triple Therapy in Comparison With Extended Sequential Therapy
This study aims to compare the efficacy of the current standard first-line anti-helicobacter pylori regimen, extended proton pump inhibitor-based sequential therapy, with that of vonoprazan-based triple therapy, through a…
- Trial name
- NCT05371249
- Testing
- Vonoprazan-based triple therapy, Extended sequential therapy
- Where
- Taiwan
- Volunteers
- 628 people
- Sponsor
- Fu Jen Catholic University Hospital
Nephrotic Syndrome, Glomerulonephritis
The Effects of Helicobacter Pylori Eradication on Proteinuria in Patients With Membranous Nephropathy
Membranous nephropathy (MN) may also be secondary to many other diseases (e.g., infections, drugs, neoplasms and autoimmune diseases). In this study, the presence of Helicobacter Pylori (H.
- Conditions
- Nephrotic Syndrome, Glomerulonephritis, Membranous Nephropathy
- Trial name
- NCT00983034
- Testing
- lansoprazole, amoxicillin, clarithromycin
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul University
Helicobacter Pylori Eradication Rate
Optimization of Vonoprazan--amoxicillin Dual Therapy for Eradicating Helicobacter Pyloriinfection
Helicobacter pylori infection is closely related to gastritis, peptic ulcer, mucosa-associated lymphoid tissue lymphoma and gastric cancer. Eradication of HP can significantly improve and reduce HP-related diseases.
- Trial name
- NCT05719831
- Testing
- vonoprazan fumarate + high dose amoxicillin（H-10d）, vonoprazan fumarate + low dose amoxicillin（L-10d), vonoprazan fumarate + amoxicillin（H-14d)
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Cardiovascular Diseases, Coronary Disease
Inflammation, Infection, and Future Cardiovascular Risk
To examine markers of underlying chronic inflammation and infection as potential risk factors for future myocardial infarction (MI), stroke (CVA), and venous thromboembolism (VTE) in plasma samples collected at baseline from…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Cerebrovascular Accident, Myocardial Infarction
- Trial name
- NCT00005496
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Bacterial Infection Due to Helicobacter Pylori (H. Pylori), Peptic Ulcer Bleeding
Helicobacter Pylori and the Long-term Risk of Peptic Ulcer Bleeding
Low-dose aspirin (ASA) has emerged as the most important cause of peptic ulcer bleeding worldwide. In western countries, ASA has overtaken non steroidal antiinflammatory drugs (NSAIDs) as a major cause of peptic ulcer bleeding in…
- Trial name
- 2NA3NANC (NCT01591486)
- Where
- China
- Volunteers
- 904 people
- Sponsor
- Chinese University of Hong Kong
Dyspepsia
Antibiotic Resistant Helicobacter Pylori in Rajavithi Hospital
Peptic ulcer disease is the most common gastrointestinal disease. Antibiotic resistant Helicobacter pylori is a major problem worldwide.
- Trial name
- NCT00285688
- Testing
- gastroscopic examination
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand