Clinical trials: Helicobacter
Helicobacter Pylori
The Situation of Re-infection of Helicobacter Pylori After Successful Eradication
The patients who accept the quadruple eradication program of the helicobacter pylori and success to eradicate helicobacter pylori will be followed-up to observe the situation of re-infection of helicobacter pylori.
- Trial name
- NCT04029493
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection
Jinghua Weikang Capsule Containing Quadruple Therapy for IgAN With Helicobacter Pylori Infection
This study is to evaluate the efficacy and safety of the Jinghua Weikang Capsule (a Chinese patent medicine for peptic ulcer and gastritis) containing quadruple therapy (Jinghua Weikang Caplsule plus triple therpy) for…
- Trial name
- NCT05320133
- Testing
- JWC containing quadruple therapy, Bismuth-containing quadruple therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Helicobacter Pylori Infection
Helicobacter Pylori Infection Occurrence in Russia
This study is planned to reveal the occurrence rate of H.pylori infection in ambulatory settings' patients in Russia and to compare the occurrence rates in different years in treatment-naïve and previously treated subjects.
- Trial name
- NCT04892238
- Testing
- 13-C urea breath test
- Where
- 2 sites in Russia
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution
H.Pylori Infection
Relation of Helicobacter Pylori in Prediabetic Patients
The primary objective of this study is to : find the relation between H.pylori infection and pre-diabetic patients with lipid profile . Specifically, the study aims to: 1. affect of H.pylori infection in pre-diabetic patients 2.
- Trial name
- NCT06176547
- Testing
- HbA1c
- Volunteers
- 82 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
15-day Sequential Therapy for Helicobacter Pylori Infection in Korea
10-day sequential therapy was not sufficient to overcome tough situation for H. pylori eradication in Korea due to high antimicrobial resistance.
- Trial name
- NCT01887249
- Testing
- Clarithromycin, metronidazole, esomeprazole
- Where
- South Korea
- Volunteers
- 287 people
- Sponsor
- Seoul National University Bundang Hospital
Immune Thrombocytopenic Purpura, Helicobacter Pylori
H. Pylori Eradication for Moderate ITP
The purpose of this study is to determine the efficacy of H. pylori eradication for the treatment of chronic or persistent immune thrombocytopenic purpura (ITP) patients with moderate thrombocytopenia.
- Conditions
- Immune Thrombocytopenic Purpura, Helicobacter Pylori, Immune Thrombocytopenia
- Trial name
- NCT03177629
- Testing
- treatment : H. pylori eradication
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Seoul National University Hospital
Helicobacter Pylori Infection
Investigation on Diagnosis and Treatment of Helicobacter Pylori Infection by Gastroenterologists in Shandong Province
Helicobacter pylori can lead to a variety of digestive system diseases.The eradication of Helicobacter pylori plays an importment role for the treatment of gastrointestinal ulcer and prevention of gastric cancer .Compared with…
- Trial name
- NCT04918134
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection
Comparing the Efficacy of 10-day Reverse Hybrid Therapy and 10-day Triple Therapy Plus Bismuth Therapy.
Reverse hybrid therapy achieves a higher eradication rate than triple therapy plus bismuth therapy remains unanswered.
- Trial name
- NCT04566211
- Testing
- (panto+amox+clar+metr)+(panto+amox), pantoprazole+bismuth+amox+clar
- Where
- Taiwan
- Volunteers
- 440 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Helicobacter Pylori Gastritis, Helicobacter Eradication
Clinical Evaluation of a 14day Modified Bismuth Quadruple Therapy for the Eradication of Helicobacter Pylori in a High Clarithromycin and Metronidazole Resistance Area Regarding Patients With Peptic Ulcer and Non Ulcer Dyspepsia
The goal of this clinical trial is to learn if a modified bismuth-containing therapy for the treatment of helicobacter pylori infection works to treat chronic helicobacter pylori related gastritis in adults treated either for…
- Trial name
- MBISQ4HP (NCT07146594)
- Testing
- Modified bismuth-containing eradication treatment
- Volunteers
- 150 people
- Sponsor
- Athens Medical Center
Thrombocytopenia
Efficacy of Helicobacter Pylori Eradication, Anti-D and Danazol Combination in Steroid Dependant or Refractory Immune Thrombocytopenia (ITP)
Proportion who would avoid splenectomy at 6 months of follow up
- Trial name
- NCT01162941
- Testing
- Steroid refractory ITP
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Cooperative Study Group A for Hematology
Helicobacter Pylori Infection
Efficacies of Antimicrobial Susceptibility-Guided Versus Empirical Therapy for Rescue Treatment of Helicobacter Pylori Infection
The purpose of this study is to assess efficacy of 14-day antimicrobial susceptibility test guided quadruple therapy for the rescue treatment of Helicobacter pylori infection, then comparing it with 14-day empirical therapy…
- Trial name
- NCT03658746
- Testing
- two sensitive antibiotics(amoxicillin, clarithromycin, metronidazole, tinidazole, levofloxacin, furazolidone and tetracycline), one proton pump inhibitor, colloidal bismuth pectin, two antibiotics based on personal medication history(amoxicillin,levofloxacin, furazolidone)
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Shandong University
Helicobacter Pylori Associated Gastrointestinal Disease
Drug-drug Interactions and Safety Among JP-1366, Amoxicillin, and Clarithromycin in Healthy Volunteers
To evaluate the effect of coadministration of amoxicillin and clarithromycin on safety, tolerability and pharmacokinetics of JP-1366 in healthy subjects and the effect of JP-1366 on safety, tolerability and pharmacokinetics of…
- Trial name
- NCT05194046
- Testing
- JP-1366 20mg 1capsule, Amoxicillin 500Mg Cap, Clarithromycin 500Mg Tab
- Where
- South Korea
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Onconic Therapeutics Inc.
Helicobacter Pylori Infection, Gastric Ulcer
Helicobacter Pylori Sample Collection Protocol Pre Therapy Subjects
The primary objective is to obtain stool samples from pre-therapy subjects already undergoing evaluation for an H. pylori infection by upper esophagogastroduodenoscopy (EGD) and gastric biopsy.
- Conditions
- Helicobacter Pylori Infection, Gastric Ulcer, Nausea, Abdominal Pain
- Trial name
- NCT03060746
- Testing
- Newly Diagnosed
- Where
- 12 sites in United States, Italy
- Volunteers
- 277 people
- Sponsor
- DiaSorin Inc.
Helicobacter Pylori Infection
Effect of Hp Infection on the Quality of Gastric Mucosa Preparation
The purpose of this study was to evaluate the effect of Helicobacter pylori infection on the quality of gastric mucosa preparation.
- Trial name
- NCT05527496
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Helicobacter Pylori Infection
Levofloxacin Concomitant Versus Levofloxacin Sequential
The goal of this trial is to determine the efficacy of levofloxacin based sequential treatment regimen or concomitant levofloxacin based regimens as empirical first-line therapy in the Syrian population
- Trial name
- NCT06065267
- Testing
- sequential, Levofloxacin 500Mg Oral Tablet
- Where
- Syria
- Volunteers
- 150 people
- Sponsor
- Damascus Hospital
Non-alcoholic Fatty Liver Disease
Helicobacter Pylori Eradication in Non-diabetic Non-alcoholic Steatohepatitis
The aim of study was to evaluate the effect of helicobacter pylori eradication on liver fat content, liver function tests, lipid profile, homeostasis model assessment-IR (HOMA-IR) index, and anthropometric measurements (body mass…
- Trial name
- NCT01654549
- Testing
- H.pylori eradication
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Helicobacter Infections, Urinary Tract Infection
First Time in Man Study of Finafloxacin Hydrochloride
The purpose of this study is to study the safety of single doses and multiple doses of Finafloxacin hydrochloride in healthy volunteers. The level of Finafloxacin hydrochloride will be measured in the subjects blood and urine.
- Trial name
- NCT00483158
- Testing
- Finafloxacin hydrochloride
- Where
- Switzerland
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- MerLion Pharmaceuticals GmbH
Persistent Helicobacter Pylori Infection
Effect of Probiotics on Eradication of Persistent H.Pylori Infection
This study aims to investigate the possible safety and efficacy of probiotics (Bifidobacterium Infants, Enterococcus Feacium, and Lactobacillus Acidophilus) on the eradication rate of Helicobacter pylori and the incidence of…
- Trial name
- NCT05674864
- Testing
- Bifidobacterium Infants plus Enterococcus Feacium plus Lactobacillus Acidophilus
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Tanta University
HELICOBACTER PYLORI INFECTIONS
Efficacy of Different Durations of Dual and Quadruple Regimens for Helicobacter Pylori Eradication
The study aimed to compare the efficacy and safety of dual and quadruple regimens with different durations (7-day, 10-day, 14-day) for the eradication of Helicobacter pylori.
- Trial name
- NCT06723197
- Testing
- vonoprazan+amoxicillin, Duration of eradication regimen: 7-day, vonoprazan+amoxicillin+tetracycline+bismuth
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection
Tailored Therapy for Clarithromycin-Resistant H. Pylori
Clarithromycin-resistant H. pylori is the main cause of H. pylori eradication failure. Tailored therapy on the basis of detection of a clarithromycin resistance mutation by PCR has been studied recently, however, there have been…
- Trial name
- NCT03431688
- Testing
- PAM, PBMT
- Where
- South Korea
- Volunteers
- 782 people
- Sponsor
- Kangdong Sacred Heart Hospital