Clinical trials: Helicobacter
Gastric Cancer, Helicobacter Pylori Infection
Helicobacter Pylori Eradication With Different Bismuth Quadruple Therapies
This study aims to compare efficacy and safety of bismuth-containing quadruple therapy（with rabeprazole amoxicillin clarithromycin）of different kinds of bismuth（Bismuth potassium citrate, pectin bismuth capsules, pectin bismuth…
- Conditions
- Gastric Cancer, Helicobacter Pylori Infection, Bismuth
- Trial name
- NCT04209933
- Testing
- Bismuth potassium citrate containing quadruple therapy, Colloidal pectin bismuth capsules containing quadruple therapy, Colloidal pectin bismuth particles A quadruple therapy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori Eradication Rate
Modified Non-clarithromycin Triple Therapy in Eradicating Helicobacter Pylori
Helicobacter pylori (H. pylori) infects more than 50% of the population in the world(1), especially 47-66% in China.
- Trial name
- NCT02776371
- Testing
- Modified non-clarithromycin triple therapy, Sequential therapy
- Where
- China
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Shandong University
Helicobacter Pylori Infection
Quadruple vs Tailored Therapy in the Treatment of Helicobacter Pylori Infection
Non-bismuth quadruple therapies have been proposed as potential strategies in improving the efficacy of first-line treatments. The non-bismuth quadruple therapy in its concomitant variant consists of proton pump inhibitor…
- Trial name
- NCT04621487
- Testing
- Amoxicillin, Metronidazole, Clarithromycin
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Helicobacter Pylori Infection
Vonoprazan in Helicobacter Pylori Treatment an RCT
RCT for comparison of Standard Triple therapy (Omeprazole+Amoxil+Clarithromycin) for H Pylori erradication with Vonoprazan+Amoxil dual therapy.
- Trial name
- NCT04901663
- Testing
- Omeprazole 20 MG Capsule; Amoxicillin 1000 MG; Clarithromycin 500 MG, Vonoprazan 20 MG; Amoxicillin 1000 MG
- Where
- Pakistan
- Volunteers
- 179 people
- Sponsor
- Dow University of Health Sciences
Helicobacter Pylori Infection
Efficacy and Safety of 14-day Concomitant Therapy for Helicobacter Pylori Infection
The purpose of this study is to evaluate efficacy of a 14-day concomitant therapy for the third-line treatment of Helicobacter pylori infection, and whether it is safe while maintaining an ideal eradication rates.
- Trial name
- NCT04991584
- Testing
- Amoxicillin,Tetracycline,Furazolidone,Levofloxacin,Vonoprazan fumarate, Esomeprazole ,
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection
Comparison Between Ten Days Sequential Treatment and Traditional Three Combined Treatment of Helicobacter Pylori
The purpose of this study is to compare the eradication efficacy of 10-day triple therapy with 10-day sequential therapy with tetracycline or metronidazole.
- Trial name
- NCT01573975
- Testing
- 5RA-5RCM, 5RA-5RCT, 10RCA
- Where
- Taiwan
- Volunteers
- 345 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Helicobacter Infections
Long-term Follow up Helicobacter Pylori Reinfection Rate After Second-Line Treatment: Bismuth-Containing Quadruple Therapy Versus Moxifloxacin-Based Triple Therapy
patients who had failed previous H. pylori eradication on standard triple therapy were randomized into two regimens: 1, esomeprazole (20 mg b.i.d), tripotassium dicitrate bismuthate (300 mg q.i.d), metronidazole (500 mg t.i.d)…
- Trial name
- NCT01792700
- Testing
- esomeprazole, tripotassium dicitrate bismuthate, metronidazole
- Where
- South Korea
- Volunteers
- 648 people
- Sponsor
- Seoul National University Bundang Hospital
Helicobacter Pylori Infection
13-C Urea Breath Test Using BreathID System and PPIs (Proton Pump Inhibitors)
Approximately 200 patients with suspected H.pylori will be tested with a 13C-Urea Breath Test (UBT) to ascertain H.pylori positive.
- Trial name
- NCT00825630
- Testing
- Lansoprazole (Lanton), Omeprezole (Losec), Pantoprazole(Controloc)
- Where
- Israel
- Volunteers
- 123 people
- Sponsor
- Meridian Bioscience, Inc.
Peptic Ulcer Hemorrhage
Helicobacter Pylori Empiric Treatment in Ulcer Bleeding
The goal of the study is to compare the effectiveness of empirical Helicobacter pylori treatment compared with treatment depending on diagnostic tests for Helicobacter pylori in patients with Upper gastrointestinal bleeding due…
- Trial name
- HETUB (NCT00687336)
- Testing
- Empirical Hp eradication, Eradication treatment guided by a positive test
- Where
- Spain
- Volunteers
- 178 people
- Sponsor
- Hospital de Sabadell
Helicobacter Pylori Infection
The Efficacy and Safety of Keverprazan for Helicobacter Pylori Eradication
The purpose of this study was to compare the efficacy of 14-day eradication of Helicobacter pylori with different doses of Keverprazan combined with Amoxicillin dual therapy and Keverprazan-based bismuth quadruple therapy and…
- Trial name
- NCT06777732
- Testing
- Keverprazan, Amoxicillin, Furazolidone
- Volunteers
- 672 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Immune Thrombocytopenic Purpura
Helicobacter Pylori Immune Thrombocytopenic Purpura
We designed a study for evaluate the efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenic purpura (ITP) patients with moderate thrombocytopenia.
- Trial name
- HpyloriITP (NCT01255332)
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Cooperative Study Group A for Hematology
Chronic Gastritis Caused by Helicobacter Pylori
Effect of Chicken Egg Antibody (IgY) on Patients With Chronic Gastritis
H. pylori positive patient volunteers that passed the selection criteria are recruited and divided into a test and a control group.
- Trial name
- NCT02721355
- Testing
- GastimunHP
- Where
- Vietnam
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Immunology Research Institute in Gifu
Helicobacter Pylori
Performances of a H. Pylori Stool PCR Test
Performance of a non-invasive test for the detection of Helicobacter pylori and its resistance to clarithromycin in stool by Real-Time PCR Amplidiag H. pylori + ClariR (Mobidiag).
- Trial name
- HEPYSTOOL (NCT03566004)
- Testing
- Stool specimen collection
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Poitiers University Hospital
Gastritis, Peptic Ulcer
H. Pylori Testing for Patients With Non-specific Upper Abdominal Pain in the Emergency Department
This pilot study aims to estimate the prevalence of Helicobacter pylori (H. pylori) colonization in patients presenting with non-specific abdominal pain (NSAP) in an urban academic emergency department (ED) located in Washington…
- Conditions
- Gastritis, Peptic Ulcer, Peptic Ulcer Perforation, Stomach Ulcer
- Trial name
- NCT01376414
- Testing
- Urea Breath Test (UBT) for H. pylori infection
- Where
- 2 sites in United States
- Volunteers
- 212 people
- Sponsor
- George Washington University
Helicobacter Pylori Infection, Helicobacter Pylori Gastritis
Helicobacter Pylori Local Prevalence and Antibiotic Resistance
The clinical management of H. pylori infection depends essentially on two factors, prevalence and local resistance. In Germany, only limited data from rather small cohorts currently exist regarding both factors.
- Conditions
- Helicobacter Pylori Infection, Helicobacter Pylori Gastritis, Drug Resistant Bacterial Infection, Antibiotic Resistant Infection
- Trial name
- HelicoPTER (NCT05561504)
- Where
- Germany
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Helicobacter Pylori Infection
10-day Versus 14-day Concomitant PAMC as First-line Treatment Strategy for the Eradication of H. Pylori Infection
Helicobacter pylori (H. pylori) infection is highly associated with gastrointestinal disorders, including peptic ulcer disease, gastric cancer, and gastric mucosa associated lymphoid tissue lymphoma.1 In 1994, H.
- Trial name
- NCT02959255
- Testing
- Esomeprazole
- Where
- Greece
- Volunteers
- 364 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Functional Dyspepsia
A Study to Evaluate the Efficacy Between Helicobacter Pylori Eradication Therapy and Motilitone in Functional Dyspepsia
This is a clinical study to evaluate the efficacy between Helicobacter pylori Eradication therapy and Motilitone in Functional Dyspepsia
- Trial name
- NCT02162316
- Testing
- Motilitone®, A-Cilin®, Clari® and Pantoline®
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Chung-Ang University Hospital
HELICOBACTER PYLORI INFECTIONS
Fecal Molecular Susceptibility-guided Hp First-line Therapy
The goal of this clinical trial is to evaluate the eradication efficacy and health economic benefits of individualized regimens guided by fecal molecular susceptibility testing with 7-day and 14-day courses in the first-line…
- Trial name
- NCT07405684
- Testing
- 7-day fecal molecular susceptibility-guided therapy, 14-day fecal molecular susceptibility-guided therapy
- Where
- 4 sites in China
- Volunteers
- 544 people
- Sponsor
- Shanghai Zhongshan Hospital
In Early Pregnancy
Helicobacter Pylori Screening at Sohag University
Screen of Helicobacter pylori in hyperemesis gravidarum in early pregnancy to detect the impact of the severity of the disease on pregnant women
- Trial name
- NCT05835076
- Testing
- Stool antigen test
- Volunteers
- 80 people
- Sponsor
- Sohag University
Lymphoma, Lymphoma, Non-Hodgkin
Helicobacter - Lymphoma - Radiation Part I: Eradication, Part II: Radiation
The first objective of this study is to confirm the results of complete remission of low-grade gastric MALT lymphoma stage IE \& II1E after H. pylori eradication on a larger number of patients (HELYX Part I).
- Trial name
- NCT00154440
- Testing
- proton pump inhibitor, clarithromycin, amoxicillin
- Where
- 3 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Technische Universität Dresden