Clinical trials: Helicobacter Pylori Eradication
Helicobacter Pylori Infection
Comparing the Efficacy of Reverse Hybrid Therapy and Bismuth Quadruple Therapy
Reverse hybrid therapy achieves a higher eradication rate than bismuth quadruple therapy remained unanswered.
- Trial name
- NCT02547038
- Testing
- pantoprazole+bismuth+tetra+metro, (panto+amox+clar+metr)+(panto+amox)
- Where
- Taiwan
- Volunteers
- 352 people
- Sponsor
- Kaohsiung Veterans General Hospital.
HELICOBACTER PYLORI INFECTIONS
Optimizing H. Pylori Eradication Regimen Under Intensified Acid Suppression
Background: Helicobacter pylori (H. pylori) infection affects approximately 50% of the global population and is closely associated with chronic gastritis, peptic ulcer disease, and gastric cancer. Eradication of H.
- Trial name
- NCT07750938
- Testing
- Keverprazan Hydrochloride 20 mg TID, Minocycline 100 mg (10-Day Regimen), Keverprazan Hydrochloride 20 mg BID
- Volunteers
- 316 people
- Sponsor
- Qilu Hospital of Shandong University
Helicobacter Pylori
The Situation of Re-infection of Helicobacter Pylori After Successful Eradication
The patients who accept the quadruple eradication program of the helicobacter pylori and success to eradicate helicobacter pylori will be followed-up to observe the situation of re-infection of helicobacter pylori.
- Trial name
- NCT04029493
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Shandong University
Positive Helicobacter Pylori Serology, Coronary Thrombosis
Effectiveness of the Eradication of Helicobacter Pylori and an Inhibitor of Pump With Proton Versus Control
Low dose of aspirin is the main cause of gastro-duodenal ulcer. The best prevention is not definite particularly in patients without history of ulcer and infected by H.
- Conditions
- Positive Helicobacter Pylori Serology, Coronary Thrombosis, Supra-aortic Artery Thrombosis
- Trial name
- Aspylori (NCT00713947)
- Testing
- during one week for the active treatments, Pantoprazole
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Helicobacter Pylori Infection
10 vs 14 Days Triple Therapy : H.Pylori Infection Eradication
Helicobacter pylori is a bacterium estimated to colonize in the gastrointestinal tract of the half population in the world. Colonization of this bacteria is suspected to be one of the main risk factor for the occurrence of…
- Trial name
- NCT03134378
- Testing
- Rabeprazole Sodium 20mg, Clarithromycin 500mg, Amoxicillin 500 Mg
- Where
- Indonesia
- Volunteers
- 73 people
- Sponsor
- Universitas Indonesia
Treatment Effectiveness
Vonoprazan for Helicobacter Pylori Eradication in Adolescents
The trial tends to evaluate the efficacy of vonoprazan-based triple therapy in eradicating H. Pylori infection in adolescent patients in Egypt, in comparison to standard treatment regimens to determine if it offers superior…
- Trial name
- NCT06162949
- Testing
- Vonoprazan, Amoxicillin, Clarithromycin
- Where
- Egypt
- Volunteers
- 242 people
- Sponsor
- Alexandria University
Gastric MALT Lymphoma
Prospective Study of First-line Antibiotic Therapy for Early-stage Gastric MALT Lymphoma for Treatment Outcome
1. The complete histological and molecular remission rate for antibiotics as 1st-line therapy for Hp-positive early-stage gastric lg- and hg-MALT lymphoma 2. The durability of complete histological remission after antibiotics 3.
- Trial name
- NCT00327132
- Testing
- Omeprazole, Amoxicillin, Clarithromycin
- Where
- 6 sites in Taiwan
- Volunteers
- 47 people
- Sponsor
- National Health Research Institutes, Taiwan
Helicobacter Pylori Infection
Study on the Effect of Fecal Microbiota Transplantation on Eradication of Refractory Helicobacter Pylori Infection
To determine whether regulating the gut microbiota can contribute to the eradication of refractory H. pylori infection.
- Trial name
- NCT07704255
- Testing
- transanal fecal bacteria transplant
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Sichuan Provincial People's Hospital
HELICOBACTER PYLORI INFECTIONS
Efficacy of Different Durations of Dual and Quadruple Regimens for Helicobacter Pylori Eradication
The study aimed to compare the efficacy and safety of dual and quadruple regimens with different durations (7-day, 10-day, 14-day) for the eradication of Helicobacter pylori.
- Trial name
- NCT06723197
- Testing
- vonoprazan+amoxicillin, Duration of eradication regimen: 7-day, vonoprazan+amoxicillin+tetracycline+bismuth
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection
Tailored Juice-guided Eradication Therapy
In this study, the investigators aim to investigate the efficacy of tailored anti-microbial susceptibility guided-therapy via gastric juice PCR, compared with empirical standard triple therapy.
- Trial name
- HP (NCT04061447)
- Testing
- susceptibility-guided therapy, empirical clarithromycin-based triple therapy
- Where
- Taiwan
- Volunteers
- 182 people
- Sponsor
- Kaohsiung Medical University