Clinical trials: Helicobacter Pylori Eradication
Helicobacter Pylori Infection
Efficacy and Safety of Tegoprazan Versus Esomeprazole-containing Bismuth Quadruple Therapy for Eradication of Helicobacter Pylori
This study is a multicenter, randomized, double-blind, double-dummy, phase III study to evaluate the efficacy and safety of tegoprazan versus esomeprazole-containing bismuth quadruple therapy in patients infected with…
- Trial name
- NCT05577468
- Testing
- Tegoprazan
- Where
- China
- Volunteers
- 561 people
- Sponsor
- Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.
H. Pylori Infection
Comparison of Rabeprazole and Esomperazole for the Eradication of H. Pylori
Patients infected with H. pylori are treated with rabeprazole 10 mg bid, AMPC 750 mg bid and CAM 200 mg bid or esomeprazole 20 mg bid, AMPC 750 mg bid and CAM 200 mg bid. Eradication rates are compared.
- Trial name
- NCT02767479
- Testing
- rabeprazole-based regimen, esomeprazole^based regimen
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Hamamatsu University
Pseudomyxoma Peritonei, Appendiceal Neoplasms
Antibiotic Treatment and Long-term Outcomes of Patients With Pseudomyxoma Peritonei of Appendiceal Origin
The purpose of this study is to determine the impact of antibiotic therapy on the disease progression and overall survival of patients with Pseudomyxoma Peritonei (PMP).
- Trial name
- NCT02387203
- Testing
- PrevPac (Prevacid, Amoxicillin, Clarithromycin)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mercy Medical Center
Immune Thrombocytopenic Purpura, HELICOBACTER PYLORI INFECTIONS
Helicobacter Pylori Eradication Therapy for Immune Thrombocytopenia (ITP) Patients in Iraq
This study is being conducted to evaluate the effect of treating Helicobacter pylori infection on platelet counts in patients with immune thrombocytopenia (ITP).
- Trial name
- NCT07150286
- Testing
- Levofloxacin-Based H. pylori Eradication Therapy
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Al-Mustansiriyah University
Peptic Ulcer With H. Pylori Infection, Gastritis With H. Pylori Infection
The Role of CYP2C19 on the Eradication of H. Pylori Infection:Implication of PK/PD Relationships
The objective of this trial is to find the rationale and the optimal dose and duration of regimen for the eradication of H. pylori infection using different proton pump inhibitors.
- Trial name
- NCT00162877
- Testing
- Rabeprazole vs. Esomeprazole
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Helicobacter Pylori Infection
ADDITION OF BISMUTH TO THE STANDARD TRIPLE THERAPY FOR HELICOBACTER PYLORI ERADICATION
H pylori is an important cause of chronic gastritis and other complications. There is a decline in eradication rate for H pylori owing to multiple factors including drug resistance.
- Trial name
- NCT03968302
- Testing
- ARM A Triple therapy for helicobacter pylori, ARM B Quadruple therapy for helicobacter pylori
- Where
- Pakistan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Helicobacter Pylori Infection, Gut Microbiota
Effect of Probiotics on Gut Microbiota During the Helicobacter Pylori Eradication
Helicobacter pylori (H. pylori) is still infecting more than half of the population in many countries, although the prevalence is decreasing. As a main cause of chronic gastritis, peptic ulcer, and malignant gastric tumors, H.
- Trial name
- NCT05662514
- Testing
- Bifidobacterium animalis subsp. lactis BLa80
- Volunteers
- 100 people
- Sponsor
- Qilu Hospital of Shandong University
Helicobacter Pylori Infection
The Efficacy of Susceptibility Test -Driven Sequential Therapy as the Third Line Therapy for Refractory Helicobacter Pylori Infection
Background: Helicobacter pylori infection has been shown to be associated with the development of gastric cancer and peptic ulcer diseases. Eradication of H.
- Trial name
- NCT01032655
- Testing
- susceptibility test guided sequential therapy
- Where
- Taiwan
- Volunteers
- 134 people
- Sponsor
- National Taiwan University Hospital
Gastric Tumor, Helicobacter Pylori
Helicobacter Pylori Eradication After Endoscopic Resection of Gastric Tumors
The purpose of this study is to determine whether Helicobacter pylori eradication could reduce the new tumor development after endoscopic resection of gastric tumor.
- Conditions
- Gastric Tumor, Helicobacter Pylori, Endoscopic Resection, Metachronous Neoplasms
- Trial name
- NCT01510730
- Testing
- eradication treatment of Helicobacter pylori infection
- Where
- South Korea
- Volunteers
- 855 people
- Sponsor
- Seoul National University Hospital
Helicobacter Pylori Infection
Effect of Dental Scaling on Helicobacter Pylori Eradication and Reinfection
Patients who had received H.pylori eradication treatment will be categorised as eradication and reinfection status and whether dental scaling has any influence on these results.
- Trial name
- Scaling and Hp (NCT01816269)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Goztepe Training and Research Hospital
Helicobacter Pylori Eradication
Efficacies of Tetracycline-levofloxacin, Standard Bismuth, Amoxicillin-levofloxacin Quadruple Therapy for H.p
1. Compare the efficacy of "Tetracycline combined with levofloxacin quadruple therapy", "standard tincture quadruple therapy" and "amoxicillin combined with levofloxacin quadruple therapy" on the second line of Helicobacter…
- Trial name
- NCT05850117
- Testing
- esomeprazole, tripotassium dicitrate bismuthate, tetracycline and levofloxacin, esomeprazole , tripotassium dicitrate bismuthate, tetracycline 500mg and metronidazole, esomeprazole, tripotassium dicitrate bismuthate , amoxicillin and levofloxacin
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- Kaohsiung Medical University
Helicobacter Pylori Infection
Sequential Therapy Versus Triple Therapy for Helicobacter Pylori Eradication: a Placebo-controlled Trial
To assess if a sequential treatment regimen better eradicates H. pylori than does a triple drug regimen in adults with dyspepsia or peptic ulcer disease.
- Trial name
- NCT00403364
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Helicobacter Pylori Infection
Clarithromycin Triple Therapy Plus Bismuth for Helicobacter Pylori First-line Treatment
Standard triple therapy including a proton pump inhibitor (PPI) and clarithromycin with either amoxicillin or metronidazole are no longer recommended as empirical first-line therapy to treat Helicobacter pylori infection because…
- Trial name
- NCT02732249
- Testing
- Esomeprazole, Bismuth Potassium Citrate, Clarithromycin
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
H Pylori Gastritis, H Pylori Infection
Efficacy of Carminal in Helicobacter Pylori Gastritis
Eighty patients will be included and randomized in two groups, one group (40 patients) will be administered 30 ml of the supplement Carminal, once a day, plus therapy for HP gastitis and the control group (40 patients) will be…
- Conditions
- H Pylori Gastritis, H Pylori Infection, H Pylori Eradication, Gastritis Associated With Helicobacter Pylori
- Trial name
- NCT07179237
- Testing
- Carminal Oral solution
- Where
- 2 sites in Serbia
- Volunteers
- 80 people
- Sponsor
- Catalysis SL
Helicobacter Infection
The Efficacy of the Tailored Therapy Based on Antimicrobial Susceptibility for 2nd Eradication of H. Pylori
As increasing the antibiotics resistance, the effectiveness of traditional Helicobacter pylori (H. pylori) therapies has been declined coincidently. In this study, the investigators evaluated the efficacy of H.
- Trial name
- NCT02349685
- Testing
- H. pylori culture and antimicrobial susceptibility test, 14 day PBMT group, 14 day MEA group
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
HELICOBACTER PYLORI INFECTIONS, Osteoporosis
Preventive Effect of H.Pylori Eradication on Osteoporosis
In this study, the investigators observed the long-term incidence rate of osteoporosis in patients who received Helicobacter pylori eradication and examined differences by age and sex.
- Trial name
- NCT06818591
- Testing
- DEXA(Dual-Energy X-ray Absorptiometry)
- Where
- South Korea
- Volunteers
- 846 people
- Sponsor
- Seoul National University Bundang Hospital
Helicobacter Pylori Infection
Antimicrobial Susceptibility for Helicobacter Pylori Eradication
Due to the high rate of resistance to clarithromycin in our area the investigators proposed an study to assess the need of antibiogram previous to the empirical OCA 10 treatment, in order to improve the rate of eradication.
- Trial name
- NCT01486082
- Testing
- OCA 10
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Hospital Donostia
Helicobacter Pylori Eradication Rate
Efficacy of Short-message-based Re-education (SMRE) on Helicobacter Pylori Eradication
Helicobacter pylori (H. pylori) is a pathogen that infects more than 50% of the human population, resulting in high healthcare costs worldwide. However, H.
- Trial name
- NCT02833623
- Testing
- Short-message-based Re-education, conventional education
- Where
- China
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Shandong University
Helicobacter Pylori
Study Comparing Sequential and Concomitant Therapy for Helicobacter Pylori Eradication in Routine Clinical Practice
Helicobacter pylori is the main cause of chronic gastritis, peptic ulcer and gastric tumors (adenocarcinoma and lymphoma). The cure of the H.
- Trial name
- NCT01273441
- Testing
- PPI, amoxicillin, metronidazole and clarithromycin
- Where
- 11 sites in Spain
- Volunteers
- 338 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Helicobacter Infection, Vonoprazan
Efficacy Comparison of 10-Day High-Dose Versus 14-Day Standard-Dose Vonoprazan Plus Amoxicillin in Helicobacter Pylori Eradication: A Multicenter Non-Inferiority Randomized Controlled Trial
This is a multicenter non-inferiority randomized controlled trial for patients infected with Helicobacter pylori. Eligible participants will be randomly split into two groups.
- Conditions
- Helicobacter Infection, Vonoprazan, Amoxicillin
- Trial name
- NCT07720037
- Testing
- 10-day group, 14-day group
- Volunteers
- 232 people
- Sponsor
- Shandong University