Clinical trials: Helping Behavior
Gait
Effect of Wearable Hip-Assist Robot on Reduction of Cardiopulmonary Metabolic Efficiency in Healthy Adults
The purpose of this study was to investigate the changes in muscle fatigue and respiratory metabolic energy expenditure during walking with wearable hip-assist robot (V3).
- Trial name
- NCT03484624
- Testing
- Treadmill walking
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Critical Illness, Sepsis
Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial
This is a prospective, unmasked, randomized, multicenter clinical trial evaluating the impact of point-of-care large language model (LLM)-based decision support on diagnostic accuracy and clinical outcomes in adult medical…
- Conditions
- Critical Illness, Sepsis, Acute Respiratory Failure (ARF), Multi-organ Failure
- Trial name
- POC-AI-ICU (NCT07293078)
- Testing
- Point-of-care large language model decision support (ChatGPT-5)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- MetroWest Artificial Intelligence Research Workgroup
Autism
Android Mobile Devices to Assist Routine Anticipation for Autistic Children
The objective of this work is to develop an application to run on a mobile device Android tablet that features visual routines for autistic children.
- Trial name
- NCT02591459
- Testing
- Using the app to assist routine anticipation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Mogi das Cruzes
Acute Respiratory Failure
NAVA Unloading - Effects on Distribution of Ventilation
Title: Reduced Unloading in NAVA Improves distribution of Ventilation in ICU patients. Objectives: 1. To investigate if NAVA targeted to moderate respiratory muscular unloading results in redistribution of ventilation to the…
- Trial name
- NCT02711722
- Testing
- Neurally adjusted ventilatory assist, PScli1, PScli2
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Karolinska University Hospital
Craniosynostosis
Qualitative and Quantitative Study Which Aims to Determine the Specifics of the Announcement for the Diagnosis of Patients With Craniosynostosis and Their Parents to Better Support Them in Their Care
The purposes of this study are: to better understand the experience of the announcement for the diagnostic of craniosynostosis to patients and their families to improve the understanding of it and it modes of appropriation to…
- Trial name
- AmAc (NCT02287805)
- Testing
- qualitative survey, quantitative survey
- Where
- France
- Volunteers
- 574 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hazardous Drinking, Harmful Alcohol Use
Telephone-Based Acceptance and Commitment Therapy for Young Adult Hazardous Drinkers
The goal of this clinical trial is to learn if telephone-based Acceptance and Commitment Therapy (ACT) works to help young adults with hazardous or harmful alcohol use quit drinking.
- Trial name
- NCT07621822
- Testing
- Telephone-Based Acceptance and Commitment Therapy (ACT), Waitlist control with Telephone-Based Social Support
- Volunteers
- 288 people
- Sponsor
- The Hong Kong Polytechnic University
Low Vision Aids, Low Vision
Pilot Study on Improving Mobility and Universal Accessibility for Individuals With Visual Disabilities in Barcelona
The project BCNMob informs about a research study approved by the Ethics Committee of the Hospital Universitario Mútua Terrassa The study aims to improve the Biel Glasses virtual reality glasses to assist patients with low vision…
- Conditions
- Low Vision Aids, Low Vision, Low Vision Blindness, Low Vision Digital Assistance
- Trial name
- BCNMob (NCT06602102)
- Testing
- Mixed reality Glasses
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Universitat Politècnica de Catalunya
Coronary Artery Disease, Heart Failure
Clinical Trial of Ventiflow LP Supporting High-risk Percutaneous Coronary Intervention(PCI)
The purpose of this prospective, multicenter, randomized controlled clinical trial is to evaluate the effectiveness of the transcatheter left ventricular assist system (Ventiflow LP) in providing circulatory support to patients…
- Conditions
- Coronary Artery Disease, Heart Failure, High-risk PCI
- Trial name
- NCT06754839
- Testing
- Percutaneous left ventricular assist device(Ventiflow LP), VA-ECMO
- Volunteers
- 250 people
- Sponsor
- Suzhou Hearthill Medical Technology Co.,LTD
Parkinson Disease
PaDAWAn: Parkinson's Disease - Adaptive Walking Assistance
The goal of this study is to develop and validate a haptic assistive method in order to support walking in patients with Parkinson's disease, delivered to the patient's hips through a wearable robotic pelvis orthosis.
- Trial name
- PaDAWAn (NCT04314973)
- Testing
- Active Pelvis Orthosis, Walking exercises
- Where
- Belgium
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Behavioral Health Client-centered Supervision
SuperAssist: Client-Centered Supervision Assist App for Mental Health Providers
The goal of this pilot study is to test a Supervision Assist App (SuperAssist) for implementing Client-Centered Supervision (CCS) to improve supervision practices for mental health providers (providers).
- Trial name
- SuperAssist (NCT07247045)
- Testing
- Client-centered supervision training and use of a mobile app
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Indiana University
Reproductive Technology, Assisted, IVF Outcomes
Reproductive Outcomes After Intracytoplasmic Sperm Injection (ICSI) With Surgically Retrieved Sperm.
This research project explores how the source of sperm affects outcomes in assisted reproductive technologies (ART), focusing on children conceived through intracytoplasmic sperm injection (ICSI) with surgically retrieved sperm…
- Conditions
- Reproductive Technology, Assisted, IVF Outcomes, ICSI
- Trial name
- SRS-ICSI outc (NCT06951061)
- Testing
- IVF/ICSI
- Where
- Sweden
- Volunteers
- 200,000 people
- Sponsor
- Karolinska Institutet
Cerebral Palsy
Feasibility of Vision-Language Models for Detecting Physical Assistance as an Observable Criterion Defining GMFCS Levels in Children Aged 2 to 6 Years With Cerebral Palsy
The GMFCS sorts children with cerebral palsy into five levels of gross motor function. What mainly separates one level from the next is two things an observer can see: whether another person has to physically help the child move…
- Trial name
- NCT07824531
- Testing
- Vision-language model assessment of movement video
- Where
- 2 sites in South Korea
- Volunteers
- 26 people
- Sponsor
- Samsung Medical Center
Respiratory Insufficiency
A Diaphragmatic Electrical Activity Based Optimization Strategy During Pressure Support Ventilation
Pressure support (PS) is a commonly used mode of ventilation which is triggered based upon the patient's own inspiratory efforts. For the most part, pressure support is well tolerated by patients.
- Trial name
- NCT02067403
- Testing
- Pressure-support Eadi optimization
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Unity Health Toronto
LVAD (Left Ventricular Assist Device)
Feasibility and Clinical Utility of Ambulatory Ultraslow Deflation Sphygmomanometers in LVAD Recipients - easiSLOW-LVAD Pilot
Prospective, single-arm feasibility study will evaluate the use of an ultraslow deflation automated sphygmomanometer (Terumo Elemano 2) for home BP monitoring in patients with continuous-flow LVADs.
- Trial name
- easiSLOW-LVAD (NCT07633561)
- Testing
- Ultraslow deflation cuff
- Volunteers
- 50 people
- Sponsor
- University of Florida
Hepatitis C, Infectious Disease
HepCare: The Effectiveness of Community Based Interventions With Peer Support to Improve Case Detection, Carry Out Pre-treatment Assessments and Assist Underserved Populations Through HCV Treatment
Hepatitis C infection is a major cause of chronic liver disease and death with approximately 3% of the world's population is infected with hepatitis C virus (HCV).
- Trial name
- NCT03524794
- Where
- United Kingdom
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University College, London
Breast Cancer Female
DEPO-Trigger Trial: GnRH Agonist DEPOt TRIGGER for Final Oocyte Maturation
For breast cancer patients who are candidates to receive chemotherapy, concurrent use of temporary ovarian suppression with gonadotropin-releasing hormone agonists (GnRHa) can be offered as ovarian protection.
- Trial name
- Depo-Trigger (NCT04616729)
- Testing
- Triptorelin 3.75 MG Injection, Transvaginal oocyte retrieval, Triptorelin Injection
- Where
- 2 sites in Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Stroke
Walk Assist Device to Improve Community Ambulation
The goal of this research study was to examine the immediate effects of a prototype wearable robotic stride management assist device (SMA) designed by Honda R\&D® on clinical walking performance, walking energetics, gait…
- Trial name
- NCT03222505
- Testing
- Honda Stride Assist Device ON, No Device Worn
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Pulmonary Hypertension
Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation
STUDY OBJECTIVES Primary objective To evaluate the effect of macitentan 10 mg on pulmonary vascular resistance (PVR) as compared to placebo in subjects with pulmonary hypertension (PH) after left ventricular assist device (LVAD)…
- Trial name
- SOPRANO (NCT02554903)
- Testing
- Macitentan 10mg
- Where
- 50 sites in United States
- Volunteers
- 57 people
- Sponsor
- Actelion
Heart Failure
C-Pulse Implantable Counterpulsation Pump (ICP) - A Heart Assist Device
The C-Pulse Study is evaluating the safety and performance of a new product for the treatment of heart failure. The product is designed to help reduce the symptoms of heart failure and help patients function better with daily…
- Trial name
- NCT01176370
- Testing
- C-Pulse™ (Implantable Counterpulsation Therapy)
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Nuwellis, Inc.
Acute Respiratory Failure
Adjusted Ventilatory Assist (NAVA-NIV) in Infants: Short-term Physiological Study
Neurally Adjusted Ventilatory Assist (NAVA) is a new form of partial support wherein the machine applies positive pressure throughout inspiration in proportion to the electrical activity of the diaphragm (EAdi), as assessed by…
- Trial name
- NCT02043990
- Testing
- Noninvasive NAVA ventilation
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
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