Clinical trials: Helping Behavior
Cognitive Burden, Cognitive Symptom
Evaluation of Impact of AI Assistance on Workload Associated w Preparation of Rare Tumor Case Repts
The goal of this study is to explore cognitive burden perceptions among physicians in relation to case report writing. Furthermore, this study evaluates the use of artificial intelligence (AI) assistance as a tool to reduce…
- Trial name
- NCT06026098
- Testing
- Artificial Intelligence
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Breast Cancer
Study to Evaluate Effectiveness of Investigational Device in the Assistance of Detection and Diagnosis of Breast Cancer
This study aims to evaluate Effectiveness of Investigational Device, Lunit INSIGHT MMG, in the assistance of Detection and Diagnosis of Breast Cancer during Screening Mammography Interpretation.
- Trial name
- NCT05615298
- Testing
- Mammography
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Lunit Inc.
Ovarian Stimulation
Lutropin Alfa in Women at Risk of Poor Response
Evaluate the effectiveness of adding lutropin alfa (recombinant human luteinizing hormone [r-hLH]) in the middle of the follicular phase compared to no addition, in infertile women at risk of poor response stimulated with…
- Trial name
- NCT01112358
- Testing
- r-FSH, r-hLH, Analogous GnRH antagonist
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Acute Hypoxemic Respiratory Failure, Mechanical Ventilation Complication
Targeting prEssure-Muscle-index to Avoid Ventilatory Over-Assistance During Pressure Support Ventilation
The TEMA study (Targeting prEssure-Muscle-index to avoid ventilatory over-Assistance during pressure support ventilation) is a prospective, interventional crossover trial investigating the relationship between pressure support…
- Trial name
- TEMA (NCT06921655)
- Testing
- Variation of Pressure Support Levels
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Centre for Medical Sciences
Knee Osteoarthritis, Knee Arthritis
Comparison of Two Robotic-Assisted Total Knee Arthroplasty Systems
The goal of this prospective study is to compare two different knee replacement robots. This study will look at patient reported outcome measures and data collected during the operation.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Disease
- Trial name
- NCT06284824
- Testing
- Stryker Triathlon with MAKO Robotic-Arm, DePuy Attune with VELYS Robotic-Assistance
- Volunteers
- 120 people
- Sponsor
- Southeast Orthopedic Specialists
Critically Ill
Mechanical Insufflation-Exsufflation (Cough Assist) in Critically Ill Adults
The goal of this randomized feasibility trial is to evaluate the feasibility of Mechanical Insufflation-Exsufflation (MI-E) in invasively ventilated critically ill patients.
- Trial name
- ACACIA (NCT06027008)
- Testing
- Mechanical Insufflation-Exsufflation
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Surgery, Bariatric Surgery Candidate
Magnetic System in Bariatric and General Surgery
Magnetic devices have been successfully used in bariatric surgery. To the date the only reported use of the magnet was for liver retraction.
- Trial name
- NCT04944810
- Testing
- Magnetic Gastric Bypass, Magnetic Sleeve Gastrectomy, Revisional Bariatric Surgery
- Where
- Venezuela
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Unidad Internacional de Cirugia Bariatrica y Metabolica
Lower Limb Ischemia
Use Art-assist and Neupogen to Treat Chronic Limb Ischemia
The purpose of this study is to measure the concentration of cells and proteins in the patient's blood during administration of Nuopogen (Filgrastim), a medication that is FDA approved for stem cell mobilization, in combination…
- Trial name
- NCT02408991
- Testing
- Neupogen, Art-Assist Device
- Where
- United States
- Sponsor
- University of Chicago
Post Traumatic Stress Disorder
Written Document to Assist Family During Decision of Withholding and Withdrawing Life-sustaining Therapies in the Intensive Care Unit
Relatives of patients in situation of withholding and withdrawing life-sustaining therapies often show post traumatic stress disorder (PTSD) (60%)[1].
- Trial name
- LATA (NCT02329418)
- Testing
- Explaining withholding and withdrawing life-sustaining therapies along with a written document, Explaining withholding and withdrawing life-sustaining therapies following standard procedure
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Grenoble
Infertility
Frozen-thawed Embryo Transfer (FTET) Cycle Follow-up Protocol (P06031)
The purpose of this follow-up study is to collect the outcome and safety of FTET cycles after the embryos are cryopreserved in P06029 (NCT01144416).
- Trial name
- NCT01146418
- Testing
- Corifollitropin alfa, recFSH (follitropin beta)
- Volunteers
- 307 people
- Sponsor
- Organon and Co
Stage D Heart Failure
Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) Study
The purpose of the study is to evaluate how well tolerated and effective an angiotensin receptor-neprilysin inhibitor (sacubitril-valsartan) is in patients with contemporary durable continuous flow left ventricular assist device…
- Trial name
- SEAL-IT (NCT04191681)
- Testing
- Sacubitril-Valsartan, Usual care (standard-of-care) arm
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Low-income Populations, Social Determinants of Health
A Mixed-Method Evaluation of the Impact of Social Risk Screening on Uptake of Social Assistance
Children are disproportionately affected by the rise in poverty rates in the United States. Economic hardships can compromise child development, overall health, and the ability to succeed in school and in life.
- Trial name
- NCT05251311
- Testing
- Social Risk Screening Tool, Electronic Resource Map, Resource Menu
- Where
- United States
- Volunteers
- 3,949 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Artificial Intelligence, Septic Shock
Artificial Intelligence for Sepsis Prediction in ICU
The development of sepsis prediction model in line with Chinese population, and extended to clinical, assist clinicians for early identification, early intervention, has a good application prospect.
- Conditions
- Artificial Intelligence, Septic Shock, Intensive Care Unit Psychosis
- Trial name
- AICUSepsis (NCT04913181)
- Testing
- Artificial intelligence sepsis prediction model
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Bottle Feeding
GrowWell - Responsive Bottle Feeding
The overall goal of this research is use digital health to augment the clinical encounter with Women, Infants, and Children (WIC) clinicians and prevent rapid infant weight gain among children living in low-income households.
- Trial name
- NCT06319807
- Testing
- Digital Health Intervention, Safety Control
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Aging
Trial of the Impact of the Electronic Frailty Integrated With Social Needs
Participants in Electronic Frailty Integrated with Social Needs (eFRIEND) will randomize to receive regularly scheduled in-person and telehealth contacts with a community health worker (CHW) or continue to receive standard of…
- Trial name
- NCT05293730
- Testing
- eFRIEND, Usual Care
- Where
- United States
- Volunteers
- 2,050 people
- Sponsor
- Wake Forest University Health Sciences
Acute Alcoholic Hepatitis
Assess Safety and Efficacy of ELAD (Extracorporeal Liver Assist System) in Subjects With Alcohol-Induced Liver Failure
The primary objective of the study is to evaluate safety and efficacy of ELAD® with respect to overall survival (OS) of subjects with a clinical diagnosis of alcohol-induced liver decompensation (AILD) up to at least Study Day…
- Trial name
- NCT01471028
- Testing
- ELAD treatment, Standard of care (Control)
- Where
- 45 sites in United States, Australia and 2 more
- Volunteers
- 203 people
- Sponsor
- Vital Therapies, Inc.
Acute Renal Failure
Open-Label Study To Evaluate the Safety and Efficacy of the Renal Assist Device In Patients With Acute Renal Failure
Although conventional hemodialysis removes waste products and corrects fluid imbalance, it does not replace critical absorptive, metabolic, endocrine, and immunologic functions performed by healthy renal tubule cells.
- Trial name
- NCT00511407
- Testing
- Renal tubule assist device
- Where
- 13 sites in United States
- Volunteers
- 58 people
- Sponsor
- RenaMed Biologics
End Stage Heart Disease
Early Versus Emergency Left Ventricular Assist Device Implantation in Patients Awaiting Cardiac Transplantation
The aim of the study is to assess whether, in patients who are listed for cardiac transplantation in transplantable (T) status, early implantation of a left ventricular assist device is superior to the current therapeutic…
- Trial name
- NCT02387112
- Testing
- Early VAD implantation
- Where
- 18 sites in Germany
- Volunteers
- 102 people
- Sponsor
- German Heart Institute
Foot Ulcer, Diabetic
Reduction of Plantar Pressure in Neuropathic Diabetic Foot Patients Using Insoles With Removable Pegs Design
The purpose of this study was to determine if insoles with removable pegs could effectively reduce the plantar aspect pressure with the aid of in-shoe plantar pressure analysis for guidance of peg removal.
- Trial name
- NCT01699100
- Testing
- device
- Volunteers
- 26 people
- Sponsor
- Taichung Veterans General Hospital
Infertility, Reproductive Techniques, Assisted
"Study of the Effects of Serum and Follicular Fluid Relaxin Levels on Ovarian Function in IVF Cycles"
The study evaluated the effect of serum relaxin and follicular fluid levels on the number and quality of oocytes, fertilization, the number and quality of the embryos in IVF protocols.
- Conditions
- Infertility, Reproductive Techniques, Assisted, Oocyte Maturation
- Trial name
- "Relaxifert" (NCT04458454)
- Testing
- Relaxin ELISA Kit
- Where
- Russia
- Volunteers
- 11 people
- Sponsor
- D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology