Clinical trials: Helping Behavior
Heart Failure, Heart-Assist Devices
Partial Left Ventricular Support in Advanced Heart Failure
Heart failure is a common condition, and the number of people with advanced disease continues to increase. We need new treatments that improve patients' symptoms and extend life.
- Trial name
- NCT01879670
- Testing
- CircuLite Synergy left ventricular assist device
- Where
- 2 sites in Belgium, United Kingdom
- Volunteers
- 2 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Overweight
Electronic Tools to Assist With Identification of and Counseling for Overweight Patients
The purpose of this study is to design and assess the impact of an electronic alert and tool set to assist with physician identification and counseling of overweight patients.
- Trial name
- NCT00973661
- Testing
- Electronic tool set for counseling overweight patients
- Where
- United States
- Volunteers
- 2,600 people
- Sponsor
- Northwestern University
Anxiety, Depression
Optimizing Duration of Therapist-guided Internet-delivered Cognitive Behaviour Therapy
Depression and anxiety are common and prevalent conditions that are frequently under treated. In an attempt to increase timely and accessible psychological treatment, Internet-delivered Cognitive Behaviour Therapy (ICBT) has…
- Trial name
- NCT04228575
- Testing
- Internet-delivered cognitive behaviour therapy
- Where
- Canada
- Volunteers
- 410 people
- Sponsor
- University of Regina
Reproductive Technology, Assisted, IVF Outcomes
Reproductive Outcomes After Intracytoplasmic Sperm Injection (ICSI) With Surgically Retrieved Sperm.
This research project explores how the source of sperm affects outcomes in assisted reproductive technologies (ART), focusing on children conceived through intracytoplasmic sperm injection (ICSI) with surgically retrieved sperm…
- Conditions
- Reproductive Technology, Assisted, IVF Outcomes, ICSI
- Trial name
- SRS-ICSI outc (NCT06951061)
- Testing
- IVF/ICSI
- Where
- Sweden
- Volunteers
- 200,000 people
- Sponsor
- Karolinska Institutet
Infertility, Ovulation Induction
SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women
Efficacy and safety studies in the past have suggested that a starting dose of 75 International Unit (IU) of SJ-0021, and an increase in the dose by 37.5 IU every 7 days, are safe for treatment of subjects with ovulatory…
- Trial name
- NCT01185782
- Testing
- Gonalef® (Follitropin alfa), Purified pituitary gonadotropin (Fertinorm-P®)
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Osteoarthritis
Total Knee Arthroplasty With Personalized Implantation: Computer Navigation-Assisted Surgery Versus Robotic-Assisted Surgery
Title: Personalized Total Knee Arthroplasty: Computer-Assisted Navigation vs. Robotic Assistance (CAN-ARD). Summary: Knee osteoarthritis is frequently treated with Total Knee Arthroplasty (TKA).
- Trial name
- CAN-ARD (NCT07574762)
- Testing
- Robotic-Arm Assisted Surgery (RA), Computer-Assisted Navigation (CAN)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Wheelchairs
Determining Levels of Function Associated With Permobil SmartDrive Manual Wheelchair Assist
This study will determine whether a power assist accessory for manual wheelchairs increases participation in community activities.
- Trial name
- NCT04973059
- Testing
- SmartDrive Summer, SmartDrive Winter
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Tobacco Smoking
EVarQuit: Extended Pre-quit Varenicline to Assist in Quitting Smoking
Varenicline is the most effective smoking cessation therapy available. Nevertheless, most smokers using varenicline relapse within the first few months after quitting.
- Trial name
- EVarQuit (NCT03262662)
- Testing
- Varenicline, Brief smoking cessation counseling
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Substance Use, Adolescent Problem Behavior
Randomized Trial of a Data-driven Technical Assistance System for Drug Prevention Coalitions
This project is designed to test the Coalition Check-Up (CCU)-a theory-based and data-driven technical assistance (TA) system that supports community coalitions' implementation of evidence-based programs (EBPs) for drug…
- Trial name
- NCT04592120
- Testing
- Coalition Check-Up
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- The University of Texas Health Science Center, Houston
Artificial Intelligence Assistance in Endoscopy Recovery, AI Validation
AI Assistance in GI Endoscopy Recovery Assessment
We have developed and validated an AI model to assess endoscopy recovery status based on 400 voice recordings from 200 patients. This model has a mean accuracy of 84.14% with a mean area under the curve (AUC) of 0.91.
- Trial name
- AIVR2 (NCT06923059)
- Testing
- AI-assisted endoscopy recovery assessment
- Where
- Hong Kong
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cardiac Rehabilitation, Heart Failure
Cardiac REhabilitation COhort at the Medicine Campus DaVos to invEstigate Recovery
The RECOVER study, titled Cardiac Rehabilitation Cohort at the Medicine Campus Davos for Exploration of Recovery, is a prospective, non-interventional, monocentric cohort study conducted at the Hochgebirgsklinik Davos.
- Conditions
- Cardiac Rehabilitation, Heart Failure, Cardiac Arrest (CA), ACS (Acute Coronary Syndrome)
- Trial name
- RECOVER (NCT07096973)
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Hochgebirgsklinik Davos
Left Ventricular Assist Device, Heart Failure
Pulse Wave Analysis in Advanced Heart Failure
A comparison of pulse wave characteristics, as measured by peripheral tonometry, in pre and post Left Ventricular Assist Device (LVAD) patients.
- Conditions
- Left Ventricular Assist Device, Heart Failure, Intra-aortic Balloon Pump, LVAD Clot
- Trial name
- PWA-HF (NCT01642927)
- Where
- United States
- Sponsor
- University of Minnesota
Heart Failure
Ventricular Assist Device (VAD) Research Registry and Blood Sub-Study
This study is meant to predict the outcome of VAD therapy, by forming a VAD registry for quality assessment, research, and real-time monitoring of patients on VAD therapy.
- Trial name
- NCT05637242
- Where
- United States
- Volunteers
- 371 people
- Sponsor
- Corewell Health West
Hepatitis C, Chronic, Hepatitis C
Compliance of HCV Genotype 1 Infected Patients Receiving PegIntron/Rebetol and a Patient Assistance Program (Study P04671)
Enrolled patients will be recruited to two parallel groups during therapy for Hepatitis C. Patients in the first one will receive a patient assistance program, and patients in the second group will not.
- Trial name
- NCT00728494
- Testing
- PegIntron (peginterferon alfa-2b; SCH 54031), Rebetol (ribavirin; SCH 18908), Patient Assistance Program
- Volunteers
- 99 people
- Sponsor
- Merck Sharp & Dohme LLC
Respiratory Failure
Non-invasive Neurally Adjusted Ventilatory Assist
Neurally adjusted ventilatory assist (NAVA) is a new concept of mechanical ventilation. NAVA delivers assistance to spontaneous breathing based on the detection of the electrical activity of the diaphragm.
- Trial name
- NCT01280383
- Testing
- non-invasive neurally adjusted ventilatory assist
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hepatitis C, Infectious Disease
HepCare: The Effectiveness of Community Based Interventions With Peer Support to Improve Case Detection, Carry Out Pre-treatment Assessments and Assist Underserved Populations Through HCV Treatment
Hepatitis C infection is a major cause of chronic liver disease and death with approximately 3% of the world's population is infected with hepatitis C virus (HCV).
- Trial name
- NCT03524794
- Where
- United Kingdom
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University College, London
Coronavirus, Inspiratory Muscle Training
Association of Inspiratory Muscle Training With HD-tDCS for Assistance to Patients With Long Covid-19
COVID-19 is an infectious disease which presents a heterogenous clinical presentation. Recent investigations suggest that people who were infected by COVID-19 often develop physical disabilities (i.e.
- Conditions
- Coronavirus, Inspiratory Muscle Training, Respiratory Infection, COVID-19
- Trial name
- NCT05359770
- Testing
- Active HD-tDCS, Control group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Suellen Marinho Andrade
Heart Failure, Heart-assist Devices
PCORI-1310-06998 Trial of a Decision Support Intervention for Patients and Caregivers Offered Destination Therapy Heart Assist Device
The left ventricular assist device (LVAD) is growing rapidly among people dying from end-stage heart failure who are unable to get a heart transplant.
- Trial name
- DECIDE-LVAD (NCT02344576)
- Testing
- DT LVAD Decision Support Intervention
- Where
- 6 sites in United States
- Volunteers
- 445 people
- Sponsor
- University of Colorado, Denver
Pediatric Surgery
Impact of an Information Assistance Application in Addition to a Traditional Anesthesia Consultation on Preoperative Anxiety in Pediatrics: Prospective Randomized Trial
The objective of the study is to evaluate the benefits on pre-operative anxiety of an information assistance application in addition to a traditional anesthesia consultation on preoperative anxiety in pediatrics
- Trial name
- Anx'Appli (NCT05401617)
- Testing
- additional information via the computerized tool
- Where
- France
- Volunteers
- 182 people
- Sponsor
- University Hospital, Rouen
Smoking Cessation
A Video-led Smoking Cessation Intervention in Helping Male Smokers Whose Partners Got Pregnant to Quit Smoking
This study aims to use a three arms randomized clinical trial study to evaluate the effectiveness of a video-led intervention in helping male smokers whose partner got pregnant in Mainland China to quit smoking.
- Trial name
- NCT03236025
- Testing
- Video+brief smoking cessation+pamphlet, Text-message+brief smoking cessation+pamphlet, brief smoking cessation+pamphlet
- Where
- Hong Kong
- Volunteers
- 1,023 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
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