Clinical trials: Helping Behavior
Angiodysplastic Bleeding
u-STOP LVAD Bleed: Utilization of Umbilical Cord Lining Stem Cells (ULSCs) To Prevent Left Ventricular Assist Device (LVAD) Associated Angiodysplastic Bleeding
This is a Phase I, single ascending dose, first in human, open-label, non-controlled, dose-escalation trial that will investigate intravenous infusions of Umbilical cord lining stem cells (UCLSCs) in Left Ventricular Assist…
- Trial name
- NCT04811261
- Testing
- Intravenous Infusion of UCLSCs
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Florida
Shaken Baby Syndrome
Parents Helping Infants Study: Educational Intervention to Change the Knowledge, Attitudes and Behaviour of New Parents About Early Infant Crying
This research project seeks to implement an early intervention program that can be effective in the prevention of shaken baby syndrome (SBS) and infant abuse.
- Trial name
- NCT00175422
- Testing
- The Period of PURPLE Crying Program
- Where
- Canada
- Volunteers
- 1,833 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Systolic Heart Failure
Frailty: Prevalence and Response to Left Ventricular Assist Device Therapy in Older Heart Failure Patients
This is an observational study evaluating changes in frailty and associated impairments in older heart failure patients receiving left ventricular assist device therapy.
- Trial name
- NCT02156583
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Thomas Jefferson University
Heart Failure, Implant Infection
Complications in Pediatric Mechanical Circulatory Assistance: Evaluation of Infection Management.
End-stage heart failure in children is a rare cause of infant mortality. The most frequent cause is dilated cardiomyopathy, often of undetermined origin, which can lead to cardiogenic shock refractory to standard medical…
- Trial name
- VADINFECT (NCT05983341)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Cardiogenic Shock, End-stage Heart Failure
ECLS Versus IMPELLA™ as Bridge to LVAD (ECI-BLAD)
In this retrospective observational multicenter study the authors tested the hypothesis that the use of IMPELLA™ pump as bridge to bridge, by giving the opportunity of active rehabilitation, should improve patient's outcomes…
- Trial name
- ECI-BLAD (NCT04480151)
- Testing
- standard of care
- Where
- 5 sites in France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Bordeaux
Heart Failure
3D Assessment of RV Function in Patients Undergoing LVAD Implantation
This goal of this study is to analyze images of the right ventricle taken via 3D transesophageal echocardiography (TEE) during left ventricular assist device (LVAD) implantation.
- Trial name
- NCT05376254
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Graves' Disease, Thyroid Disease
Shared Decision Making in Graves Disease - Graves Disease (GD) Choice
The investigators' decision aid for patients with GD, GD Choice, will be the result of a user-centered participatory action research involving) synthesis of the best available evidence from the literature and real-world registry…
- Conditions
- Graves' Disease, Thyroid Disease, Hyperthyroidism
- Trial name
- NCT02107794
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Mayo Clinic
Stress, Psychological, Compassion Fatigue
Achieving Resilience in Acute Care Nurses (ARISE).
Nurses are exposed to myriad stressors, both in the workplace and in their everyday lives, which can lead to adverse personal and professional outcomes.
- Trial name
- NCT03017469
- Testing
- ARISE
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Unity Health Toronto
Stroke, Stroke Rehabilitation
Volunteer Facilitated Discharge Assistance and Supports at Home (DASH) for People With Stroke
The goal of this clinical trial is to learn if a home visit by a trained volunteer can improve stroke recovery after a stroke survivor is discharged home from the hospital. The main questions it aims to answer are: 1.
- Conditions
- Stroke, Stroke Rehabilitation, Transitional Care
- Trial name
- DASH (NCT07590076)
- Testing
- Discharge Assistance and Supports at Home (DASH)
- Where
- 6 sites in Canada
- Volunteers
- 840 people
- Sponsor
- Bruyère Health Research Institute.
Knee Arthritis
Oxford Unicompartmental Knee Arthroplasty With and Without Navigational Unit
The purpose of this study is to determine whether a computer navigational unit can improve operating time and consistency during Knee arthroplasty when compared to knee arthroplasty without a computer navigational unit.
- Trial name
- NCT00862316
- Testing
- Oxford Unicompartmental Knee
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Zimmer Biomet
Drug Use
The Impact of Alternative Social Assistance Disbursement on Drug-related Harm
This study evaluates whether altering the timing and frequency of social assistance disbursement reduces drug related-harms that increase on the days surrounding monthly synchronized government social assistance cheque issue.
- Trial name
- TASA (NCT02457949)
- Testing
- Non-synchronized social assistance receipt, cheque divided into two equal disbursements
- Where
- Canada
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Parkinson Disease, Driving Impaired
Using Advanced Driver Assistance Systems (ADAS) as an Intervention Strategy for Drivers With Parkinson's Disease
Parkinson's disease (PD) impacts an individual's fitness to drive in a number of ways that increase the crash risk in this population.
- Trial name
- NCT03195608
- Testing
- Lane change assistance system, Active Control
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Western University, Canada
Arm Weakness as a Consequence of Stroke
Effects of Post-Stroke Upper Extremity Assistance
The purpose of this study is to quantify the improvement of post- stroke individuals' ability to move their arms during and after robot assisted therapy.
- Trial name
- NCT05036642
- Testing
- Compliant Passive Arm Support
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Chronic Obstructive Pulmonary Disease
Hyaluronic Acid in Acute Exacerbation of COPD - Duration Of Noninvasive Assistance
The objective of this study is to test the effect of High Molecular Weight Hyaluronic Acid (HMW-HA) on Non Invasive Ventilation (NIV) effectiveness in patients admitted to a sub-intensive care unit for respiratory failure due to…
- Trial name
- HAEC-DONA (NCT02674880)
- Testing
- HMW-HA
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- Campus Bio-Medico University
Gastric Subepithelial Tumor
Endoscopic Full Thickness Resection With Laparoscopic Assistance
The purpose of this study is to evaluate the feasibility of endoscopic full-thickness resection with laparoscopic assistance.
- Trial name
- EFTR-LA (NCT02042079)
- Testing
- EFTR with LA
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- National Cancer Center, Korea
Infertility
Use of Predictive Model to Assist Patients Having an Embryo Transfer After IVF
To determine in women undergoing IVF who are at high risk of multiple births (>35%), as calculated by the application of a predictive model - IVFsingleTM, if single embryo transfer will lead to both comparable clinical pregnancy…
- Trial name
- NCT02009891
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Fertility Centre
Health Promotion, Obesity
Study of a Learning Collaborative to Implement Health Promotion in Mental Health
Healthcare organizations have increasingly formed quality-improvement Learning Collaboratives to improve care for specific populations; however, there are few data on the effectiveness of this strategy compared to conventional…
- Conditions
- Health Promotion, Obesity, Organizational Innovation, Mental Health Services
- Trial name
- NCT03891368
- Testing
- Virtual Learning Collaborative, Technical Assistance
- Volunteers
- 55 people
- Sponsor
- Massachusetts General Hospital
Heart Failure, Coronary Artery Disease
IMAGE-HF Project I-A: Cardiac Imaging in Ischemic Heart Failure (AIMI-HF)
Medical imaging is one of the fastest growing sectors in health care and increases in utilization underscore the need to ensure imaging technology is developed and used effectively.
- Conditions
- Heart Failure, Coronary Artery Disease, Ischemic Cardiomyopathy
- Trial name
- AIMI-HF (NCT01288560)
- Testing
- Advanced cardiac imaging, Standard Cardiac Imaging
- Where
- 20 sites in United States, Argentina and 3 more
- Volunteers
- 1,390 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Stroke
Reducing Asymmetry During Gait Using the TPAD (Tethered Pelvic Assist Device) for Stroke Patients
OBJECTIVES: The purpose of this study is to evaluate the overall feasibility in terms of safety, treatment tolerance and adherence as well as preliminarily address how effective this treatment model using the TPAD and overground…
- Trial name
- NCT03203291
- Testing
- TPAD (Tethered Pelvic Assist Device)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Columbia University
Heart Failure, Systolic, Left Ventricular Assist Device
STandardized Ultra-conservative Or Physician-directed ICD Programming for Continuous Flow LVAD Support
This study will evaluate the utilization of an ultra-conservative programming strategy to reduce shocks for ventricular arrhythmias (VA) among patients with heart failure, an implantable cardioverter-defibrillator (ICD) and…
- Conditions
- Heart Failure, Systolic, Left Ventricular Assist Device, ICD
- Trial name
- NCT04264182
- Testing
- ICD programming
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The Cleveland Clinic
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