Clinical trials: Hematologic Tests
Dysphagia, Eosinophilic Esophagitis
The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States
Background: Eosinophilic esophagitis (EoE) is a disease that causes inflammation in the esophagus. The esophagus is the tube that moves food from the mouth to the stomach.
- Trial name
- NCT07027826
- Testing
- Esophageal string test
- Where
- 3 sites in United States, Mali
- Volunteers
- 70 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Advanced Lymphoma, Advanced Malignant Solid Neoplasm
Testing Crizotinib as a Potential Targeted Treatment in Cancers With ROS1 Genetic Changes (MATCH-Subprotocol G)
This phase II MATCH treatment trial identifies the effects of crizotinib in patients whose cancer has a genetic change called ROS1 translocation.
- Conditions
- Advanced Lymphoma, Advanced Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm, Refractory Lymphoma
- Trial name
- NCT04439253
- Testing
- Crizotinib
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer
Personalizing Chemotherapy Selection After Surgery for Patients With Stage III Colorectal Cancer Using a Blood Test
CIRCULATE-III is an international, multicenter, open-label, randomized phase III trial designed to use ctDNA as a selection criterion for intensification or de-escalation of adjuvant chemotherapy.
- Trial name
- CIRCULATEIII (NCT07340567)
- Testing
- Capecitabine, Oxaliplatin, Folfirinox
- Where
- 5 sites in France, Sweden
- Volunteers
- 2,450 people
- Sponsor
- UNICANCER
Solid Tumors, Hematological Malignancies
Molecular Testing of Cancer by Integrated Genomic, Transcriptomic, and Proteomic Analysis
The purpose of this study is to discover genetic changes associated with different cancers. With the information from this study the investigators hope to provide better ways to prevent, detect and treat many cancers.
- Trial name
- NCT02213822
- Testing
- Molecular Analysis of Cancer
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Rhode Island Hospital
Red-Cell Aplasia, Pure, Chronic Renal Failure
Study to Monitor the Incidence of Pure Red Cell Aplasia (PRCA) and/or Antibodies to Erythropoietin Among Participants Receiving Epoetin Alfa or Another Erythropoietin
The purpose of this study is to assess the incidence of pure red cell aplasia (PRCA [suppression of erythropoiesis with little or no abnormality of leukocyte or platelet production]) among participants with chronic renal failure…
- Trial name
- NCT00210951
- Testing
- No Intervention
- Volunteers
- 4,761 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
HIV Infections, Syphilis Infection
GUM Remote Testing v4.0
Capillary blood sample results are compared to venous blood results
- Conditions
- HIV Infections, Syphilis Infection, Hepatitis B and Hepatitis C
- Trial name
- NCT06244966
- Testing
- HIV diagnostic testing
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Thoracic Cancer, Ovarian Cancer
Project CADENCE (CAncer Detected Early caN be CurEd)
With existing evidence showing the difference in miRNA expression levels between non-cancer and cancer groups, the investigators assume that levels of DNA methylation, RNA expression as well as protein concentration will also be…
- Conditions
- Thoracic Cancer, Ovarian Cancer, Liver Cancer, Prostate Cancer
- Trial name
- CADENCE (NCT05633342)
- Where
- Singapore
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- MiRXES Pte Ltd
Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia
Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling
Functional precision medicine (FPM) is a relatively new approach to cancer therapy based on direct exposure of patient- isolated tumor cells to clinically approved drugs and integrates ex vivo drug sensitivity testing (DST) and…
- Conditions
- Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Large Cell Lymphoma, Refractory Childhood Acute Lymphoblastic Leukemia
- Trial name
- NCT05857969
- Testing
- Functional Precision Medicine
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Florida International University
Acetaminophen Overdose
Acute Acetaminophen Ingestion: Does Repeated Acetaminophen Blood Test Have an Interest?
Acetaminophen is the first drug involved in voluntary drug poisoning. According to the studies conducted in the USA and in the United Kingdom, it is the first cause of acute liver failure, and this poisoning is responsible of 10…
- Trial name
- NCT01692639
- Where
- 10 sites in France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Strasbourg, France
Healthy, Blood Cell Count
Blood Testing at Entia
The investigators are recruiting healthy volunteers to donate 1-5 (depending on study visits. and donors will be notified upon invitation) finger prick blood samples or venous samples to Entia for the further development and…
- Trial name
- NCT05580055
- Testing
- Affinity
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Entia Ltd
Anemia
The Effect of Blood Tests Performed Within the Routine Protocol in the Surgical Intensive Care Unit on Hemoglobin Levels
Examination of blood samples is inevitable in intensive care units. Routine blood samples can be an important cause for anemia. In this study, we aimed to examine how our blood collection routine affects hemoglobin values.
- Trial name
- NCT05833178
- Testing
- Drawn Blood Volume
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Samsun University
Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
This phase III trial compares the effect of adding sonrotoclax to zanubrutinib versus zanubrutinib alone for the treatment of patients with untreated chronic lymphoblastic leukemia (CLL)/small lymphocytic lymphoma (SLL).
- Trial name
- NCT07321652
- Testing
- Zanubrutinib, Sonrotoclax, Computed Tomography
- Where
- 224 sites in United States
- Volunteers
- 466 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Ischemic (Brain) Stroke, Hemorrhagic Stroke
Prehospital Advanced Diagnostics and Treatment of Acute Stroke
The objective of this study is to investigate the effectiveness of prehospital diagnosis and, when appropriate, of intravenous thrombolytic treatment of ischemic stroke.
- Conditions
- Ischemic (Brain) Stroke, Hemorrhagic Stroke, TIA, Brain
- Trial name
- Treat-NASPP (NCT03158259)
- Testing
- Prehospital diagnosis and treatment
- Where
- Norway
- Volunteers
- 400 people
- Sponsor
- Norwegian Air Ambulance Foundation
Colon Cancer
OctavaColon Cancer Blood Tests OctavaGold and OctavaSilver - Blood Tests for the Help in Diagnosis of Colon Cancer Clinical Study Protocol
The OctavaColon tests are qualitative plasma tests that are indicated to people above 18 years of age suspected with colon abnormality.
- Trial name
- NCT02066259
- Where
- 3 sites in Israel
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- Eventus Diagnostics Ltd
Thromboembolism, Blood Coagulation Disorders
Patient-Centered Anticoagulation Self-Monitoring in Minority Patients
The purpose of this study is to demonstrate the feasibility and effectiveness of anticoagulation self-monitoring coupled with an educational intervention in a minority underserved population.
- Conditions
- Thromboembolism, Blood Coagulation Disorders, Cardiovascular Disease, Vascular Disease
- Trial name
- NCT02776566
- Testing
- Patient Self-Monitoring vs Anticoagulation Clinic
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Illinois Chicago
Depression - Major Depressive Disorder, Schizophenia Disorder
A Novel Blood Test as a Biomarker in Mental Health
This longitudinal, observational study aims to assess whether the characteristics of a novel blood peripheral biomarker can serve as indicators for depression and schizophrenia in patients at the Royal Columbian Hospital…
- Conditions
- Depression - Major Depressive Disorder, Schizophenia Disorder, Psychosis, Mania (Neurotic)
- Trial name
- LEADING-MH (NCT06856161)
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Fraser Health
Haemostasis Disorders
Investigation of Systemic and Regional Haemostasis During Liver Transplantation by Comparing ClotPro® and TEG®
The purpose of the research is to compare the global and the portal haemostasis during liver transplantation by functional investigations using TEG® and ClotPro® tests.
- Trial name
- NCT04246307
- Testing
- TEG® and ClotPro® parameters
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Colorectal Disorders
Increasing Uptake of Colorectal Cancer Screening in Ontario
The investigators hope to determine whether the addition of an FOBT kit and educational materials to a second mailed invitation compared to a second mailed invitation alone increases use of appropriate screening tests (FOBT for…
- Trial name
- NCT01629004
- Testing
- FOBT kit, Mailed invitation
- Where
- Canada
- Volunteers
- 5,155 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Hemophilia
Motor Proficiency of People With Bleeding Disorders Using the BOT-2 (TM)
The purpose of this study is to find out if gross motor skills of children and young adults with bleeding disorders are different from those without bleeding disorders.
- Trial name
- NCT02279199
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Infection
Recognition of Serious Infections in the Elderly
The aim of this diagnostic accuracy study is to develop a clinical prediction rule based on signs, symptoms, patient characteristics and blood tests, to be used in ambulatory care to help physicians safely rule out a serious…
- Trial name
- ROSIE (NCT04516187)
- Testing
- signs and symptoms, blood tests
- Where
- 12 sites in Belgium
- Volunteers
- 493 people
- Sponsor
- KU Leuven