Clinical trials: Hemiparesis
Stroke, Stroke, Acute
Safety Evaluation of the ReWalk ReStore Device in Subjects With Mobility Impairments Due to Stroke
A multi-site, interventional, non-comparative, single-arm trial to evaluate the safety of the ReWalk ReStore device in subjects with hemiplegia/hemiparesis due to ischemic or hemorrhagic stroke.
- Conditions
- Stroke, Stroke, Acute, Stroke Hemorrhagic, Hemiparesis
- Trial name
- NCT03499210
- Testing
- ReWalk ReStore device
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- ReWalk Robotics, Inc.
Stroke, Cerebrovascular Accident (CVA)
Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke
The purpose of this study is to evaluate if multiple therapy sessions of Transcutaneous Vagus Nerve Stimulation (tVNS) combined with robotic arm therapy lead to a greater functional recovery in upper limb mobility after stroke…
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Hemiparesis
- Trial name
- tVNS (NCT03592745)
- Testing
- Transcutaneous Vagus Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Northwell Health
Stroke, Hemiparesis
Error Enhancement of the Velocity Component
The purpose of this pilot study was to explore the impact of enhancement of the velocity component error in the course of reaching movements of the impaired/hemiparetic limb in an acute stroke subject.
- Trial name
- NCT02017093
- Testing
- Error Enhancement, control treatment
- Where
- Israel
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis)
Effects of Unilateral Robotic Assistance on Compensation Strategies and Muscular Activity During Hemiparetic Gait
Hemiparetic gait is characterized by strong asymmetries that could severely affect the quality of life of stroke survivors. This asymmetry is due to motor deficits in the paretic leg and the resulting compensations in the…
- Trial name
- NCT05138211
- Testing
- Exoskeleton assisted gait on a treadmill
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Spanish National Research Council
Hemiparesis
A Music-based VR Intervention for Upper Limb Motor Rehabilitation in Hemiparetic Patients
Hemiparesis affects the majority of stroke patients in the acute phase. In post-stroke motor rehabilitation patients can re-learn motor sequences through repetitive training.
- Trial name
- NCT04977609
- Testing
- VR+MUSIC, VR, TAU
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Catholic University of the Sacred Heart
Rasmussen Encephalitis
Efficacy of Tacrolimus and I.V.-Immunoglobulins in Rasmussen Encephalitis
Rasmussen encephalitis (RE) is a rare but severe chronic inflammatory brain disease of unknown origin affecting one brain hemisphere. It is usually accompanied by intractable epilepsy.
- Trial name
- NCT00545493
- Testing
- Tacrolimus, i.v. immunoglobulins
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- University Hospital, Bonn
Stroke, Autonomic Dysfunction
Repetitive Transcranial Magnetic Stimulation in Cardiac Autonomic Dysfunction
The aim of this study is to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) added to conventional neurological rehabilitation on heart rate variability (HRV), quality of life, upper extremity muscle…
- Conditions
- Stroke, Autonomic Dysfunction, Hemiparesis
- Trial name
- NCT07482501
- Testing
- rTMS M1 Motor Cortex Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Afyonkarahisar Health Sciences University
Severe Stroke, Acute Stroke
Stroke Rehabilitation With Exoskeleton-assisted Gait.
Gait recovery is one of the main goals of post-stroke rehabilitation where robotic-assisted practice has shown positive outcomes. However, literature lacks of clinical studies on exoskeleton-supported gait rehabilitation.
- Conditions
- Severe Stroke, Acute Stroke, Chronic Stroke, Cerebrovascular Disorders
- Trial name
- EKSOGAIT (NCT03395717)
- Testing
- Exoskeleton-Assisted Gait Training
- Where
- 4 sites in Italy
- Volunteers
- 162 people
- Sponsor
- IRCCS San Raffaele Roma
Chronic Stroke, Hemiplegia
Implementing Technology Enhanced Real Time Action Observation Therapy in Persons With Chronic Stroke
This is a feasibility study to alter the Microsoft Kinect software to be used as a rehabilitation tool. The prototype used is still in the early developing stage.
- Conditions
- Chronic Stroke, Hemiplegia, Hemiparesis, Paralysis
- Trial name
- TERTAOT (NCT03780296)
- Testing
- Real-time action observation with augmented Kinect
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Michigan
Stroke, Hemiparesis
Retraining the Walking Pattern After Stroke
The purpose of the study is to determine the effects of pairing gait training with different forms of visual feedback about leg movements in individual post-stroke to modify/normalize their gait pattern over time.
- Trial name
- NCT03813342
- Testing
- Gait training with visual feedback of joint kinematics
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Stroke with Hemiparesis, Stroke
Impact of the BOOST GAIT Program on Gait Recovery and Functional Mobility After Stroke
The overarching goal is to determine if the BOOST GAIT program can improve functional mobility in patients with stroke who are undergoing inpatient rehabilitation and have some walking function, through the application of…
- Trial name
- BOOST GAIT (NCT06612359)
- Testing
- BOOST GAIT Program
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Hasselt University
Stroke, Réhabilitation
Pilot Study: Home Use of Wearable Grasping Neuroprosthesis in Vascular Hemiparesis
Stroke is the leading cause of acquired motor disability in adults. Six months post-stroke, 50% of patients have not regained active finger extension, and 80% retain a grasping deficit, most commonly an inability to actively open…
- Trial name
- GRASP-HOME (NCT07500480)
- Testing
- Evaluation of neuroprosthesis control methods, Neuroprosthesis implantation, Pre-use assessments of the neuroprosthesis in a hospital setting
- Where
- 2 sites in France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Toulouse
Stroke, Ischemic, Stroke
Validation of a Brain-Computer Interface for Stroke Neurological Upper Limb Rehabilitation
The study's main goal is to determine if clinical and physiological effects of a brain-computer interface intervention for the neurorehabilitation of stroke patients' upper limb are greater than the effects of a sham robotic…
- Trial name
- NCT04724824
- Testing
- Brain-Computer Interface
- Where
- Mexico
- Volunteers
- 23 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Stroke, Upper Limb Motor Impairment
tDCS Combined With Constraint-Induced Therapy in Post-Stroke Upper Limb Rehabilitation
The objective of this clinical trial is to evaluate the effects of transcranial direct current stimulation (tDCS) combined with constraint-induced therapy (CIT) on upper limb motor recovery in individuals after stroke.
- Conditions
- Stroke, Upper Limb Motor Impairment, Post-Stroke Hemiparesis
- Trial name
- tDCS-CIT Strok (NCT07458503)
- Testing
- transcranial direct current stimulation (tDCS), Constraint-induced movement therapy
- Where
- 2 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade do Estado do Pará
Cerebral Palsy, Movement Disorder
Rehabilitation Gaming System for Cerebral Palsy
In this study the investigators evaluate the effectivity of Virtual Reality-based rehabilitation protocols for preventing motor deterioration in patients with cerebral palsy.
- Trial name
- NCT02938754
- Testing
- VR-based motor training, Conventional Therapy
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Universitat Pompeu Fabra
Upper Extremity Paresis, Hemiplegia and/or Hemiparesis Following Stroke
Task or Virtual Reality Intervention for Improving UE Function
People with one arm that does not function well due to a stroke, head injury, or cerebral palsy, and a fully functional other arm, will be randomly assigned to receive one of the two interventions first, followed by the other…
- Conditions
- Upper Extremity Paresis, Hemiplegia and/or Hemiparesis Following Stroke, Hemiplegic Cerebral Palsy
- Trial name
- NCT03811275
- Testing
- Virtual Reality (A) then Task (B), Task (B) then Virtual Reality (A)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Idaho State University
Hemiparesis Proprioceptive Disorders Gait, Hemiplegic, Healthy Individual, Comparative Study
Lower Extremity Proprioception Sensory and Functionality in Hemiparetic
The loss of sensorial feedback causes gait impairment in hemiparesis. The studies show that proprioceptive impairment of knee is related to falling in these patients.
- Trial name
- NCT05062187
- Testing
- Proprioseption in hemiparetics
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Stroke
Adaptive Dance Activities for People With Stroke
The project will investigate the effects of a novel 12-week Movement Improvisation Skill-building and Adaptive Dance Intervention (MDI) on participation, balance, mobility, balance confidence, psychological well-being, and…
- Trial name
- MDI (NCT07591272)
- Testing
- Movement Improvisation Skill-building and Adaptive Dance Intervention
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- Chinese University of Hong Kong
The Effectiveness of Novel Rehabilitation Device on Upper Limb Impairment Among Patients With Stroke
Usability and Effectiveness of a Novel Bilateral Upper Limb Training Device for Stroke Patients With Hemiparesis: A Preliminary Study
Background and Study Aims Stroke is a leading cause of long-term disability worldwide, affecting millions of individuals each year.
- Trial name
- Synslai (NCT06956677)
- Testing
- Novel UE rehabilitation device training, The UE functional training, Conventional occupational therapy
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- Chang Gung Memorial Hospital
Unilateral Cerebral Palsy
Sensitivity of an Upper Limb Motion Analysis Protocol to Changes in Kinematics and Muscle Activity After Constraint Induced Therapy in Children With Hemiplegia
In France, Cerebral Palsy (CP) affects 1 in 450 births. It results from lesions of the brain, before, during, or shortly after birth. These non-progressive lesions cause muscle impairments, responsible for activity limitations.
- Trial name
- MouvsupTCIHemi (NCT03099993)
- Testing
- Measurement of maximal forces of elbow pronosupination and flexion-extension
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital