Clinical trials: Hemiparesis After Stroke
Stroke
fNIRS Neurofeedback for Post-stroke Hand Rehabilitation
Cardiovascular diseases are one of the main causes of disability. Among post-stroke individuals, 80% experience upper limb dysfunction, while only 5% to 20% of individuals regain full limb and hand function.
- Trial name
- NCT07262528
- Testing
- Standard Rehabilitation supplemented with Biofeedback HEG, Standard Rehabilitation
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- University of Rzeszow
Post-stroke Hemiparesis
Innovative Closed-loop Functional Electrical Stimulation Control System for Augmenting Post-stroke Gait
This study will compare the performance of a novel data-driven model-predictive controller (MPC) based functional electrical stimulation (FES) system versus a conventional FES system for footdrop correction during treadmill and…
- Trial name
- NCT07189819
- Testing
- Model-Predictive Controller (MPC) Functional Electrical Stimulation (FES), Conventional Functional Electrical Stimulation (FES)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Hemiparesis After Stroke, Traumatic Brain Injury
Partial Blocks of Rectus Femoris and Soleus With Botulinum Toxin Type A (Xeomin®) to Improve Gait in Hemiparesis
The most common motor deficiency after stroke or traumatic brain injury is hemiparesis. Most hemiparetic patients recover walking, but rarely with a speed permitting easy ambulation outdoors with family or friends.
- Trial name
- GENUFLEX (NCT03119948)
- Testing
- Botulinum toxin injection
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Post-stroke Hemiparesis
Operant Conditioning of Reflex Pathways to Improve Walking in Individuals Post-stroke
The purpose of this study is to examine the changes in reflex pathways in the paretic ankle plantarflexors in individuals with post-stroke hemiparesis using operant conditioning.
- Conditions
- Stroke, Post-stroke Hemiparesis, Foot Drop
- Trial name
- NCT05801744
- Testing
- Operant conditioning
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Stroke, Hemiparesis After Stroke
Optimizing Cortical Priming
Each year over 795,000 people suffer from stroke resulting in the primary cause of adult disability. Persistent upper limb dysfunction due to stroke significantly impairs performance and results in a serious decline of quality of…
- Trial name
- NCT07860073
- Testing
- 5 Hz Repetitive transcranial magnetic stimulation (rTMS) on the contralesional dorsal premotor cortex (cPMd), 5 Hz Repetitive transcranial magnetic stimulation (rTMS) on the ipsilesional primary motor cortex (iM1)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wan-Wen Liao
Stroke, Hemiparesis
Retraining the Walking Pattern After Stroke
The purpose of the study is to determine the effects of pairing gait training with different forms of visual feedback about leg movements in individual post-stroke to modify/normalize their gait pattern over time.
- Trial name
- NCT03813342
- Testing
- Gait training with visual feedback of joint kinematics
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Stroke, Aphasia Following Cerebral Infarction
Combined Aphasia and Robot-Assisted Arm Treatment for Chronic Stroke Survivors
The goal of this clinical trial is to learn if a program that combines language and arm treatment can improve language and movement problems in people with chronic stroke.
- Conditions
- Stroke, Aphasia Following Cerebral Infarction, Hemiparesis After Stroke
- Trial name
- CARAT (NCT07000019)
- Testing
- CARAT: combined aphasia and robot-assisted arm therapy, Robot-assisted arm therapy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- New York Medical College
Stroke, Hemiparesis
Biomarkers for Prediction of Hand Function After Stroke - The ProHand Study
The overall aim is to identify key determinants for recovery of hand function after stroke by applying newly developed hand function measures together with MRI measurements of the lesioned cerebral structures.
- Trial name
- ProHand (NCT02878304)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Danderyd Hospital
Hemiparesis After Stroke, Dual Energy X-ray Absorptiometry
Radiographic Cortical Thickness of the Humerus in Detecting Post-Stroke Regional Bone Loss
Post-stroke immobilization and reduced weight-bearing frequently lead to significant regional bone mineral density loss and asymmetry, particularly in the paretic upper extremity, which increases fracture risks.
- Conditions
- Hemiparesis After Stroke, Dual Energy X-ray Absorptiometry, Osteoporosis
- Trial name
- NCT07651306
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Stroke, Movement Disorders
Robot Therapy for Rehabilitation of Hand Movement After Stroke
A study will be performed where individuals with chronic stroke will be randomly assigned to receive 2 different dosages of robotic hand therapy.
- Conditions
- Stroke, Movement Disorders, Hemiparesis
- Trial name
- HEXORR (NCT04536987)
- Testing
- HEXORR
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Catholic University of America
Stroke, Hemiparesis
Examining How Motor Rehabilitation Promotes Brain Reorganization Following Stroke, an MRI Study
Constraint-induced movement therapy (CI therapy) is a highly efficacious treatment for residual motor disability in chronic stroke.
- Trial name
- NCT01725919
- Testing
- CI therapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Ohio State University
Stroke
Gait Training in Post-Stroke Hemiparesis Hemiparesis
The focus of this study is to optimize the delivery of a combined strength and aerobic training regimen to individuals with post stroke hemiparesis and reduce overuse and inefficiencies associated with the nonparetic leg during…
- Trial name
- NCT04877249
- Testing
- Split-belt treadmill training
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Stroke, Hemiparesis
Motor Imagery BCI Rehabilitation After Stroke
This research project will investigate motor imagery training in stroke rehabilitation during which patients receive feedback in real time from their brain activity measured with ElectroEncephaloGraphy (EEG).
- Trial name
- NCT04847089
- Testing
- Motor imagery BCI training
- Where
- 3 sites in Sweden
- Volunteers
- 16 people
- Sponsor
- Mälardalen University
Hemiplegia and/or Hemiparesis Following Stroke
The Effect of Blood Flow Restriction Training on Lower Limb Motor Function in Stroke Patients With Hemiplegia
flow restriction training combined with routine rehabilitation training can promote the recovery of lower limb muscle strength on the hemiplegic side of stroke patients, improve the lower limb motor function of patients, and…
- Trial name
- NCT06461013
- Testing
- Blood flow restriction
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yunhong Tian
Stroke With Hemiparesis
Study of Botulinum Toxin and Recovery of Hand Function After Stroke
The purpose of this study is to determine whether injections of botulinum toxin (commonly known as BOTOX®) into the affected hand of Stroke patients, while targeting the muscles controlling the hand, will lead to improved use of…
- Trial name
- NCT01422161
- Testing
- Botulinum Toxin commonly known as BOTOX®
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NYU Langone Health
Stroke, Chronic Stroke
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
The main purpose of the current studies is to evaluate the safety and tolerability of psilocybin in patients with chronic stroke.
- Conditions
- Stroke, Chronic Stroke, Intracerebral Haemorrhage, Intracerebral Haemorrhage (ICH)
- Trial name
- PHATHOM (NCT07053917)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Stroke, Brain Infarction
Arm Rehabilitation Study After Stroke
This study is about arm and hand recovery after a stroke. The investigators are testing an experimental arm therapy called Accelerated Skill Acquisition Program (ASAP) which combines challenging, intensive and meaningful practice…
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- ICARE (NCT00871715)
- Testing
- Accelerated Skill Acquisition Program (ASAP), Dose-Equivalent Usual & Customary Care - DEUCC, Usual and Customary Care - UCC
- Where
- 8 sites in United States
- Volunteers
- 361 people
- Sponsor
- University of Southern California
Stroke, Hemiparesis
EEG Brain-Machine Interface Control of an Upper-Limb Robotic Exoskeleton for Robot-Assisted Rehabilitation After Stroke
The goal of this study is to develop a clinically feasible, low-cost, nonsurgical neurorobotic system for restoring function to motor-impaired stroke survivors that can be used at the clinic or at home.
- Trial name
- NeuroExo (NCT05374486)
- Testing
- NeuroExo co-robot neurorehabilitation system
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Houston
Stroke, Hemiparesis
Sensorimotor Arm Rehabilitation After Stroke
Hemiparesis is a frequently observed symptom of stroke. There are various therapy options that are used in the rehabilitation of patients.
- Trial name
- TAB-APP (NCT05590988)
- Testing
- Tablet-based training, ergotherapeutic training
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Hemiparesis of the Upper Limb Following Stroke
MyndMove Therapy for Severe Hemiparesis of the Upper Limb Following Stroke
The purpose of this study is to examine the efficacy of MyndMove therapy in the early sub-acute, late sub-acute and chronic post-stroke patients.
- Trial name
- NCT02266836
- Testing
- MyndMove
- Where
- 6 sites in Canada
- Volunteers
- 50 people
- Sponsor
- MyndTec Inc.