Clinical trials: Hemodialysis Complication
End Stage Renal Disease
Effect of Omega-3 Fatty Acids on Oxidative Stress and Dyslipidemia in Pediatric Patients Undergoing Hemodialysis
The purpose of the study is to evaluate the effect of omega-3 fatty acids supplementation on pediatric patients undergoing hemodialysis via the measurement of the following before and after omega-3 administration:oxidative stress…
- Trial name
- NCT02581449
- Testing
- omega-3, empty soft gelatin capsules
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
End Stage Renal Disease, Hemodialysis Access Failure
PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis
The goal of this observational study is to increase the understanding of the safety and performance of Merit Medical's HeRO Graft System (HeRO) and Super HeRO Adaptor and Support Seal System (Super HeRO) devices.
- Trial name
- PReSeRVE-HD (NCT06422871)
- Testing
- HeRO® Graft System or Super HeRO® System
- Where
- 7 sites in United States
- Volunteers
- 100 people
- Sponsor
- Merit Medical Systems, Inc.
End-Stage Kidney Disease (ESKD)
Virtual Reality-Guided Imagery in Hemodialysis Patients ( VRGI-HD )
This randomized controlled trial aims to evaluate the effect of virtual reality guided imagery on selected health outcomes among adult patients receiving maintenance hemodialysis.
- Trial name
- NCT07867444
- Testing
- virtual reality-guided imagery (VRGI)
- Volunteers
- 80 people
- Sponsor
- Islamic University of Najaf
Secondary Hyperparathyroidism
Observational Program of Zemplar in Patients With End Stage Chronic Kidney Disease and Parathyroid Disorder on Hemodialysis in the Russian Federation
Eighty-six eligible participants with secondary hyperparathyroidism will be enrolled at thirteen sites in Russia. Planned therapy will be six months.
- Trial name
- NCT01401478
- Where
- 13 sites in Russia
- Volunteers
- 86 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Narrative Nursing, Maintenance Hemodialysis
Construction of Theoretical Model of Medical Treatment Behavior of Patients With Chronic Kidney Disease
The impact of narrative nursing interventions on negative emotions, self-efficacy, quality of life in individuals undergoing maintenance hemodialysis
- Conditions
- Narrative Nursing, Maintenance Hemodialysis, Chronic Kidney Diseases
- Trial name
- NCT06175585
- Testing
- narrative nursing, traditional nursing
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanxi Medical University
Kidney Failure, Chronic, Drug Resistance
REPEAT Study - Resistance to ErythroPoietin Effectiveness Algorithm Trial
A strategy for optimizing erythropoietin therapy in patients with erythropoietin resistance. A multi-centered, open-label, randomized, controlled trial.
- Trial name
- NCT00319150
- Testing
- erythropoietin
- Where
- 7 sites in Canada
- Volunteers
- 6 people
- Sponsor
- Queen's University
Chronic Kidney Failure, Acute Kidney Failure
Theranova Randomized, Controlled, Trial (RCT) in China
Traditional hemodialysis (HD) therapy is very effective in clearing urea and smaller middle molecules, but is limited in clearing larger middle molecules.
- Trial name
- ROCKet (NCT05309291)
- Testing
- Theranova 400 Dialyzer, FX 800 Dialyzer
- Where
- 10 sites in China
- Volunteers
- 323 people
- Sponsor
- Vantive Health LLC
Hemodialysis Patients
Effects of Exercise Program on Physical Functioning of Hemodialysis Patients.
This study is designed to provide a simple, home-based, low-moderate intensity exercise program in chronic renal disease patients who are undergoing hemodialysis in order to improve physical performance, decrease the level of…
- Trial name
- NCT04674930
- Testing
- Exercise program
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Dialysis; Complications, Performance Enhancing Product Use
Effects of Short Term Creatine Supplementation in Hemodialysis Patients
Adult patients undergoing chronic dialysis therapy for at least three months were selected. A physical function assessment was conducted, including the Short Physical Performance Battery (SPPB) and a handgrip strength test.
- Trial name
- NCT07033611
- Testing
- Creatine
- Where
- Chile
- Volunteers
- 18 people
- Sponsor
- Carla Basualto Alarcón
Kidney Failure, Chronic, End-Stage Renal Disease
Comparison of Nocturnal Hemodialysis (NHD) and Short Daily Hemodialysis (DHD) With the NxStage® System One™
The purpose of this study is to determine whether or not nocturnal hemodialysis is equivalent to short daily hemodialysis on a per treatment basis, using the NxStage System One in the home setting.
- Trial name
- NCT00667511
- Testing
- NxStage System One
- Where
- 9 sites in United States
- Volunteers
- 58 people
- Sponsor
- NxStage Medical
Renal Failure, Acute Renal Failure
Premarket Clinical Safety Assessment of the ELISIO™-HX
The primary safety objective of this study is to evaluate the safety of the use of the high-permeability hemodialyzer series ELISIO™-HX, by showing that the pre-dialysis albumin levels are not affected using the investigational…
- Conditions
- Renal Failure, Acute Renal Failure, Chronic Renal Failure, Chronic Kidney Diseases
- Trial name
- NCT07058909
- Testing
- ELISIO™-HX Dialyzer
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Nipro Medical Corporation
End-stage Renal Disease
Impact of Dialysis Modality on Hepcidin and Iron Metabolism
Dialysis modality may influence the oxidative stress and proinflammatory cytokines in ESRD patients. Dialysis modality may affect hepcidin Dialysis modality may influence iron and ESA requirements.
- Trial name
- HERMES (NCT01723111)
- Where
- 4 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- Kyungpook National University Hospital
Secondary Hyperparathyroidism
A Study to Evaluate the Effect of ASP7991 in Secondary Hyperparathyroidism Patients Undergoing Hemodialysis
To examine efficacy and safety after 12-week administration of ASP7991 in secondary hyperparathyroidism patients undergoing hemodialysis
- Trial name
- NCT02133404
- Testing
- ASP7991, Cinacalcet
- Where
- 6 sites in Japan
- Volunteers
- 62 people
- Sponsor
- Astellas Pharma Inc
Renal Failure Chronic, Hepatitis C
Multi-center Study to Transplant Hepatitis-C Infected Kidneys
Open label multi center study for the donation of HCV positive kidneys to HCV negative recipients with interventional treatment to prevent HCV transmission upon transplantation.
- Trial name
- MYTHIC (NCT03781726)
- Testing
- glecaprevir/pibrentasvir treatment
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- Raymond Chung
Complication of Dialysis, Chronic Kidney Disease
Efficacy of Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation in Hemodialysis Patients
The purpose of this study is to examine the effect of 6 months of daily beta-hydroxy beta-methylbutyrate (HMB) supplementation on the physical function and the health of bones, arteries and heart in hemodialysis patients.
- Conditions
- Complication of Dialysis, Chronic Kidney Disease, Muscle Loss, End Stage Renal Disease
- Trial name
- NCT01837238
- Testing
- HMB
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Illinois at Urbana-Champaign
Secondary Hyperparathyroidism, End Stage Renal Disease
Efficacy and Safety of Alfacalcidol Compared to Calcitriol for Treatment of Secondary Hyperparathyroidism
This study was performed to determine whether calcitriol provides a therapeutic advantage to alfacalcidol for treatment of secondary hyperparathyroidism in ESRD patients.
- Trial name
- NCT01115543
- Testing
- alfacalcidol and calcitriol
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Chronic Kidney Disease, Hemodialysis
Nicotinamide in Hemodialysis Patients With Hyperphosphatemia
Study hypothesis: Nicotinamide inhibits gastrointestinal phosphate absorption and serum phosphate levels of dialysis patients in a dose dependent manner.
- Conditions
- Chronic Kidney Disease, Hemodialysis, Hyperphosphatemia
- Trial name
- DONATO (NCT01200784)
- Testing
- Nicotinamide
- Where
- 36 sites in Germany
- Volunteers
- 252 people
- Sponsor
- Medice Arzneimittel Pütter GmbH & Co KG
Chronic Kidney Disease Stage 5
Exercise and Vascular Function in Haemodialysis Patients
The aim of this study is to evaluate whether a three month intra-dialytic exercise programme improves arterial function.
- Trial name
- NCT01591876
- Testing
- Intradialytic aerobic exercise, Progressive Muscle relaxation
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Queen Margaret University
Renal Disease, High Blood Pressure
Blood Pressure Change and Outcome
Hyper- and hypotension are important predictors of survival in non-ESRD (end stage renal disease) population. In dialysis patients, however, it has been shown that higher blood pressure levels may actually be beneficial to…
- Trial name
- BP (NCT01330004)
- Where
- United States
- Volunteers
- 12,695 people
- Sponsor
- Renal Research Institute
Chronic Kidney Disease Requiring Chronic Dialysis
Intradialytic Pedalling Exercise and Vascular Hemodynamic Parameters Among Prevalent Hemodialysis Population
The purpose of this pilot study is to evaluate 1) the effect of intradialytic pedaling exercise on arterial stiffness and other arterial hemodynamic parameters over 4 months, and 2) the longer-term effect of pedaling on arterial…
- Trial name
- NCT03027778
- Testing
- Exercise
- Volunteers
- 32 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre