Clinical trials: Hemodialysis Patients
Covid19, End Stage Renal Failure on Dialysis
Safety of Remdesivir Treatment in COVID-19 Patients Requiring Hemodialysis
The FDA approved the antiviral drug remdesivir for use in adults for the treatment of COVID-19 requiring hospitalization. There are only limited data about the safety of the drug in hemodialysed patents.
- Trial name
- REM-HD (NCT04854837)
- Testing
- Remdesivir
- Where
- Hungary
- Volunteers
- 45 people
- Sponsor
- Semmelweis University
Chronic Kidney Diseases
Quality of Life in Patients Transitioning to Home or In-Center Dialysis (QUALIFY CKD-to-HOME)
The goal of this study is to evaluate quality of life (QoL) and frailty trajectories from advanced chronic kidney disease (CKD) to after dialysis initiation, specifically comparing patients choosing home dialysis and in-center…
- Trial name
- NCT06458322
- Testing
- Home dialysis or In-Center dialysis
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
End Stage Kidney Disease
Hemodynamics in Chronic Hemodialysis Patients Undergoing Isolated Ultrafiltration Compared to Conventional Hemodialysis
Patients treated with hemodialysis (HD) bear increased risk of cardiovascular events, which results in high morbidity and mortality among this cohort of patients.
- Trial name
- ISO-UF (NCT05642156)
- Testing
- isolated Ultrafiltration (iso-UF)
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Medical University of Graz
Chronic Kidney Disease on Hemodialysis
The Self-management Program on Hemodialysis Patients in Cambodia
Chronic kidney disease (CKD) is a growing global health issue, with increasing numbers of patients requiring kidney replacement therapy (KRT), particularly in low- and middle-income countries.
- Trial name
- NCT06871553
- Testing
- Self management education program
- Where
- Cambodia
- Volunteers
- 45 people
- Sponsor
- Hiroshima University
Hemodialysis, Diabete Mellitus
Continuous Glucose Monitoring in Dialysis Patients to Overcome Dysglycemia Trial
This randomized controlled trial will investigate whether use of continuous glucose monitoring (CGM) vs. usual care with self-monitored blood glucose 1) enhances glycemic control, 2) reduces hypoglycemia risk, and 3) improves…
- Conditions
- Hemodialysis, Diabete Mellitus, Continuous Glucose Monitoring
- Trial name
- CONDOR (NCT05509881)
- Testing
- Continuous glucose monitoring (CGM), Usual care (Self-monitored blood glucose)
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of California, Irvine
Kidney Failure, Chronic
Insulin-like Growth Factor (IGF-I) in Hemodialysis Patients
The purpose of this study is to investigate whether the anabolic potentials of insulin may be used to reverse the catabolic effects of hemodialysis in non-diabetic patients with end-stage renal failure.
- Trial name
- NCT01209403
- Testing
- Glucose-infusion, Glucose-insulin infusion
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Renal Failure, Impaired Renal Function
Linezolid Pharmacokinetics In Patients With Impaired Renal Function (PPT6)
Renal failure patients were treated with linezolid (LZD) for proven or suspected infections by multiresistant Gram-positive cocci.
- Trial name
- LZDPPT6 (NCT02087566)
- Testing
- 600 mg linezolid
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Hemodialysis Patients
Dietary Sodium Restriction in Hemodialysis Patients
Excess dietary sodium can lead to poor outcomes, such as hypertension, edema and increased risk for cardiovascular diseases. These complications are associated with end stage renal disease (ESRD) progression and mortality in…
- Trial name
- NCT01896882
- Testing
- Sodium restriction
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Dialysis Patients
Intradialytic Exercise With Blood Flow Restriction in Hemodialysis Patients
The main objective is to evaluate in hemodialysis patients the effects of two intradialytic rehabilitation programs based on physical exercise, with or without the application of blood flow restriction, on myocardial stunning and…
- Trial name
- ERO-CARD (NCT07269379)
- Testing
- Chronic phase - HDEX/HDBFRE, Acute phase - HDEX/HDBFRE
- Where
- 2 sites in France
- Volunteers
- 108 people
- Sponsor
- University of Avignon
Chronic Renal Failure
Effect of Omega 3 Fatty Acids on the Vascular Calcification Biomarkers Fetuin A and Osteoprotegerin in Patients With CRF
study the effect of omega 3fatty acids on the vascular calcification biomarkers Fetuin -A and Osteoprotegerin (OPG) in dialysis patients.
- Trial name
- CRF (NCT03982966)
- Testing
- Omega 3 fatty acids (fish oil) 1000 mg/day oral
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour University
Complication of Hemodialysis
The Relationship Between the Flow of Arteriovenous Fistula and Cardiac Function in Haemodialysis Patients
A prospective longitudinal surveillance for a period of 2 months. Sample - identify suitable Chronic Kidney Disease (CKD) patients who undergo HD with functioning AVF.
- Trial name
- NCT02747966
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Hepatitis B
Evaluation of Immunogenicity, Reactogenicity and Safety of HBV-MPL Vaccine vs Engerix™-B, in Haemodialysis Patients
This trial is designed to evaluate the immunogenicity, reactogenicity and safety of an MPL-adjuvanted recombinant hepatitis B vaccine in comparison with those of Engerix™-B in haemodialysis patients with or without previous…
- Trial name
- NCT00699231
- Testing
- HBV-MPL vaccine 208129, Engerix™-B
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- GlaxoSmithKline
Intradialytic Hypotension
Evaluation of the Impact of L- Carnitine in Intradialytic Hypotension in Pediatric Patients on Regular Hemodialysis
Intradialytic hypotension (IDH) is defined as less than the 5th percentile of SBP measurements and is associated with clinical symptoms, such as abdominal pain, nausea, vomiting, muscle cramps, restlessness, light-headedness…
- Trial name
- NCT05905692
- Testing
- L Carnitine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Chronic Renal Failure Requiring Hemodialysis
Oxidative Stress on Muscle Dysfunction in Hemodialysis Patient
In hemodialysis patient (HD) a reduction of the skeletal muscle mass and strength has previously been reported. This muscle impairment constitutes an independent prognosis factor in HD patients.
- Trial name
- POPEYE (NCT02794142)
- Testing
- renal transplantation, No intervention
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Complication of Hemodialysis, Hyperthyroidism Treated or Under Control
Early Administration of L-carnitine in Hemodialysis Patients
Hemodialysis is a cause of carnitine deficiency. The deficiency of carnitine induces an anemia by an increase fragility of the red blood cells, a muscular fatigue and a cardiac dysfunction.
- Trial name
- NCT00322322
- Testing
- L-Carnitine
- Where
- 2 sites in France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vascular Access Complication, Hemodialysis Access Failure
Optimizing Access Surgery In Senior Hemodialysis Patients
The number of elderly hemodialysis patients is growing. Vascular access complications are a major determinant of the quality of life and health care costs for these vulnerable patients.
- Conditions
- Vascular Access Complication, Hemodialysis Access Failure, Dialysis Access Malfunction, Arteriovenous Fistula
- Trial name
- OASIS (NCT05911451)
- Testing
- Arteriovenous fistula creation, Arteriovenous graft placement, Central venous catheter placement
- Where
- 20 sites in Netherlands
- Volunteers
- 166 people
- Sponsor
- Maastricht University Medical Center
Anemia in End Stage Renal Disease
Study of Rule-Based Algorithms in Anemia Management in Prevalent Hemodialysis Patients and Its Relation to Patients' Outcomes
The study will assess role of rule based algorithm in anemia management in hemodialysis patients and its relation to patient's mortality
- Trial name
- NCT06996717
- Testing
- ESA
- Where
- Egypt
- Volunteers
- 145 people
- Sponsor
- Ain Shams University
Chronic Renal Failure
Safety Study of TRK-820 for Patient With Hemodialysis
The purpose of this study is to observe pharmacokinetics and safety of nalfurafine hydrochloride in patients receiving hemodialysis.
- Trial name
- TRK-820 (NCT01248650)
- Testing
- nalfurafine hydrochloride
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- SK Chemicals Co., Ltd.
Hemodialysis, Metabolic Syndrome X
The Study of Metabolic Syndrome in Hemodialysis Patients
Metabolic syndrome (MS), comprised of central obesity, glucose intolerance, hyperinsulinemia, low HDL-cholesterol (HDL-C), high triglyceride (TG) and hypertension, results in markedly increased risk for cardiovascular disease in…
- Conditions
- Hemodialysis, Metabolic Syndrome X, Insulin Resistance
- Trial name
- NCT00632879
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Far Eastern Memorial Hospital
Chronic Kidney Disease (Stages 4 and 5), Hemodialysis
Intradialytic Rehabilitation and Functional Independence in Hemodialysis Patients
This study evaluated whether a rehabilitation program performed during hemodialysis sessions could improve daily functioning and mobility in adults receiving maintenance hemodialysis.
- Trial name
- NCT07442240
- Testing
- Dynamic Lumbar Stabilization Exercises, Respiratory Muscle Training
- Volunteers
- 56 people
- Sponsor
- Bandırma Onyedi Eylül University
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