Clinical trials: Hemodialysis Patients
End-stage Renal Disease
Pharmacokinetics and Dialyzability of Dapagliflozin in Dialysis Patients
Sodium-glucose co-transporter 2 inhibitors (Sglt2i) attenuate the incidence of cardiovascular events in individuals with preserved or mildly reduced kidney function.
- Trial name
- DARE-ESKD 1 (NCT05343078)
- Testing
- Dapagliflozin 10Mg Tab
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- University of Campinas, Brazil
Renal Osteodystrophy
12-month Study of AMG 073 in Renal Osteodystrophy
4 doses of AMG 073 or placebo over 52 weeks after a 30-day screening period. Throughout the study, labs will be drawn to measure analytes such as iPTH and corrected calcium.
- Trial name
- NCT00527085
- Testing
- AMG 073
- Volunteers
- 45 people
- Sponsor
- Amgen
Kidney Disease, Chronic, End Stage Renal Disease
The Effect of Exercise on Dialysis Patients' Survival
The purpose of this study is to check if patients' exercise during their dialysis sessions can prevent their early deaths.
- Conditions
- Kidney Disease, Chronic, End Stage Renal Disease, Hemodialysis
- Trial name
- NCT04898608
- Testing
- Intradialytic Exercise
- Where
- 2 sites in Iran
- Volunteers
- 74 people
- Sponsor
- Pardis Specialized Wellness Institute
Hyperparathyroidism, Secondary
Extension Study of Etelcalcetide for Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease on Hemodialysis
This is a multicenter, single-arm, extension study to characterize the long-term safety and tolerability of etelcalcetide in the treatment of Secondary Hyperparathyroidism (SHPT) in adults with Chronic Kidney Disease (CKD) on…
- Trial name
- NCT02102204
- Testing
- Etelcalcetide
- Where
- 228 sites in United States, Australia and 22 more
- Volunteers
- 902 people
- Sponsor
- Amgen
Inflammation, Oxidative Stress
The Influence of Cessation of Pomegranate Juice Intake on Inflammation and Oxidative Stress Markers and Glucose Control in Diabetic and Non Diabetic Chronic Hemodialysis Patients
The current study will investigate chronic hemodialysis patients who were treated in our unit with pomegranate juice intake for 1 year - compared to a control group.
- Trial name
- NCT01033435
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 49 people
- Sponsor
- Western Galilee Hospital-Nahariya
ESRD
Psychosocial Reasons for Transfer to In Center Hemodialysis in Home Dialysis Patients- A Focus Group Study
Patients who start home dialysis take on an added responsibility and that can be challenging. The investigators are interested in studying the patient and care partner perspective on the challenges that the participants faced on…
- Trial name
- NCT05022225
- Testing
- None. This is a qualitative interview study.
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Satellite Healthcare
Anemia
Ferumoxytol Versus Oral Iron in the Treatment of Anemia in Hemodialysis Patients
The study will evaluate the safety and efficacy of a new intravenously administered iron drug to treat anemia in patients on hemodialysis.
- Trial name
- NCT00233597
- Testing
- ferumoxytol or oral iron
- Where
- 50 sites in United States
- Volunteers
- 230 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Infection Catheter-Related
Using Antibiotics to Prevent Infections in Hemodialysis Patients During Catheter Placement
The goal of this clinical trial is to determine if prophylactic antibiotic treatment can reduce the incidence of early catheter-related infections in hemodialysis patients at high risk, including those with femoral catheter…
- Trial name
- NCT06814223
- Testing
- • Cefamezine (2 grams) and gentamicin (80 mg) administered intravenously. • Patients with penicillin allergies, a history of methicillin-resistant Staphylococcus aureus (MRSA) infection, or known MRSA
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Western Galilee Hospital-Nahariya
Chronic Kidney Diseases
Assessment of Professional Practices in Muscle Rehabilitation of Chronic Hemodialysis
Aim of this study is to evaluate, in a population of chronic kidney disease patients on dialysis (Stage 5D), the effect of a muscle strengthening program (training against resistance vs endurance training by elliptical bike)…
- Trial name
- REHABIMUS (NCT04820140)
- Testing
- Lymphatic drainage
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Montpellier
Hemodialysis, Life Quality
Weight Management of Dialysis Patients
The goal of this clinical trial is to Improve the quality of life in Hemodialysis patient. The main questions it aims to answer are: [Improve the self-compliance of dialysis patients with weight management] [alleviate the volume…
- Conditions
- Hemodialysis, Life Quality, Interdialytic Weight Gain, Cardiovascular Events
- Trial name
- NCT06333574
- Testing
- Family weight self-measurement and remote follow-up management based on wechat., Routine care
- Volunteers
- 100 people
- Sponsor
- qinxiu zhang
Hyperphosphatemia Patients on Hemodialysis
A Phase 2 Study of TS-172 in Hyperphosphatemia Patients on Hemodialysis With Phosphate Binders
A phase 2, randomized, placebo-controlled, double-blind, phosphate binder-combination study of TS-172 in hyperphosphatemia patients on hemodialysis
- Trial name
- NCT06745518
- Testing
- TS-172
- Where
- Japan
- Volunteers
- 62 people
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Hyperkalemia
SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients
This study aims to compare the effects of Sodium Zirconium Cyclosilicate versus Sodium Polystyrene Sulfonate for treatment of hyperkalemia in patients undergoing regular hemodialysis.
- Trial name
- NCT06029179
- Testing
- sodium zirconium cyclosilicate (SZC), sodium polystyrene sulfonate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Chronic Kidney Disease Requiring Hemodialysis
Cardiovascular Effects of SGLT2 Inhibitors in Hemodialysis Patients: A Phase 2 Randomized Study
Patients with end-stage kidney disease (ESKD) on hemodialysis face an unacceptably high rate of cardiovascular complications, including heart failure, arrhythmias, and sudden cardiac death.
- Trial name
- SGLT2-HD (NCT06929169)
- Testing
- iSGLT2
- Where
- Argentina
- Volunteers
- 80 people
- Sponsor
- Maximo Agustin Schiavone
Hemodialysis Complication
Effect of Lactobacillus Rhamnosus on Serum Uremic Toxins in Hemodialysis
Uremic toxins such as p-cresol and phenol are suggested to be associated with higher mortality in hemodialysis patients. The aim of this study was to investigate the effects of probiotics on serum p-cresol level in hemodialysis…
- Trial name
- NCT03527680
- Testing
- Lactobacillus rhamnosus
- Volunteers
- 42 people
- Sponsor
- nooshin dalili
Immunosuppression
Influenza Vaccination in Immunocompromized Patients
Evaluation of the immunogenicity and reactogenicity of two different formulations of commercially avail-able influenza vaccines in 4 different groups of immunocompromized outpatients (HIV positive patients, patients suffering…
- Trial name
- NCT00783380
- Testing
- Virosomal influenza vaccine, Subunit influenza vaccine
- Where
- 3 sites in Switzerland
- Volunteers
- 304 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
End Stage Renal Disease
Study in End Stage Renal Disease (ESRD) Patients on Hemodialysis Comparing the Theranova Dialyzer to Hemodiafiltration
In China, the estimated prevalence of patients with ESRD receiving PD or maintenance HD increased from 51.7 per million population (pmp) at the end of 2007 to 79.1 pmp at the end of 2008.
- Trial name
- NCT03547336
- Testing
- Theranova 400 Dialyzer, FX800 Dialyzer
- Where
- 8 sites in China
- Volunteers
- 212 people
- Sponsor
- Vantive Health LLC
Hemodialysis Complication
Exercise Therapy on Rheological Functions of Erythrocyte in Hemodialysis
To improve aerobic capacity, muscular function, and health-related quality of life in patients with end-stage renal disease (ESRD), regular exercise is recommended.
- Trial name
- NCT06575634
- Testing
- Supervised exercise training
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Hyperphosphatemia Patients on Hemodialysis
A Long-term Study of TS-172 in Hyperphosphatemia Patients on Hemodialysis
A clinical study to evaluate the long-term safety and efficacy of TS-172 in hyperphosphatemia patients on hemodialysis.
- Trial name
- NCT07285304
- Testing
- TS-172
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Kidney Failure, Chronic
Effects of Gum Arabic Supplementation in Hemodialysis Patients
Gum Arabic is a naturally produced gummy exudate from Acacia Senegal tree. It's a complex polysaccharide with proven prebiotic properties.
- Trial name
- NCT03789708
- Testing
- Gum Arabic
- Where
- Sudan
- Volunteers
- 80 people
- Sponsor
- University of Khartoum
Chronic Renal Failure Requiring Hemodialysis
A Phase 3, Long-Term Safety Study of Intravenous Epoetin Hospira in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin
The purpose of the study is to determine the long-term safety in treatment-emergent adverse events (TEAEs) of intravenous (IV) administration of Epoetin Hospira for maintenance of target hemoglobin (Hgb) levels in patients…
- Trial name
- AiME - 03 (NCT01628107)
- Testing
- Epoetin Hospira
- Where
- 110 sites in United States, Puerto Rico
- Volunteers
- 406 people
- Sponsor
- Pfizer
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