Clinical trials: Hemodialysis Patients
End Stage Renal Disease, Fatigue
Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis
Fatigue is the most common symptom reported by end-stage kidney disease patients on maintenance hemodialysis. Unfortunately, there currently is no medical management for this overwhelming feeling of tiredness.
- Trial name
- BRISK (NCT06609343)
- Testing
- Bupropion Hydrochloride 150 MG
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Kidney Failure, Chronic, Renal Disease, End-Stage
Pharmacokinetics/Pharmacodynamics of Argatroban Injection in End-Stage Renal Disease Patients Undergoing Hemodialysis
The primary goals of this investigation are to provide guidance on how to dose Argatroban in patients undergoing hemodialysis and to assess the safety and tolerability of Argatroban in hemodialysis patients.
- Trial name
- NCT00035178
- Testing
- Argatroban
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Texas Biotechnology Corporation
End Stage Renal Disease (ESRD), Brachiocephalic Fistula (BCF)
Outcome of BCF Access in Hemodialysis Patients
Dialysis access, which is the connection that allows blood to flow in and out of the body during dialysis sessions, is important to remove wastes and excess fluid for patients with end stage renal disease (ESRD).
- Conditions
- End Stage Renal Disease (ESRD), Brachiocephalic Fistula (BCF), Cephalic Arch Stenosis (CAS), Dialysis
- Trial name
- BCF (NCT01693263)
- Testing
- brachiocephalic fistula (BCF)
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Chicago
End Stage Renal Disease, Sexual Dysfunction, Physiological
Pain, Sexual Dysfunction, and Depression in Hemodialysis Patients
This study is seeking to identify the most effective strategy to manage pain, sexual dysfunction, and depression in patients receiving chronic hemodialysis therapy.
- Conditions
- End Stage Renal Disease, Sexual Dysfunction, Physiological, Pain, Depression
- Trial name
- SMILE (NCT00692419)
- Testing
- Symptom management nurse intervention, Feedback intervention
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- US Department of Veterans Affairs
End-stage Renal Disease
Effects of Strict Volume Control in Hypertensive Hemodialysis Patients on Cardiac Structure and Chronic Inflammation
This study aims mainly to investigate the effects of two approaches to control blood pressure in hypertensive hemodialysis patients; using antihypertensive drugs versus strict volume control (by strict dietary salt restriction…
- Trial name
- NCT00307463
- Testing
- strict volume control policy, antihypertensive drugs administration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 258 people
- Sponsor
- Ege University
Hypoalbuminemia, Protein-energy Malnutrition
Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients
Study of efficiency and safety of oral nutritional supplements with anti-inflammatory and antioxidative properties combined with an appetite stimulant with anti-inflammatory properties (pentoxiphylline) in treatment of…
- Conditions
- Hypoalbuminemia, Protein-energy Malnutrition, Inflammation, Oxidative Stress
- Trial name
- AIONID (NCT00561093)
- Testing
- pentoxiphylline, Nepro, anti-inflammatory module (similar to Oxepa)
- Where
- 2 sites in United States
- Volunteers
- 93 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Secondary Hyperparathyroidism
Safety, Tolerability and Efficacy of Etelcalcetide in Hemodialysis Patients With Secondary Hyperparathyroidism
The purpose of this study is to characterize the safety and tolerability and efficacy of multiple ascending doses of etelcalcetide in hemodialysis patients for the treatment of secondary hyperparathyroidism (HPT).
- Trial name
- NCT01254565
- Testing
- Etelcalcetide
- Where
- 13 sites in United States
- Volunteers
- 87 people
- Sponsor
- KAI Pharmaceuticals
Hypertension in Dialysis Patients, Fluid Overload in Dialysis Patients
Prepared Meals to Prime and Perpetuate Reduced Dietary Sodium Intake in Hemodialysis
This is a randomized clinical trial in which maintenance hemodialysis patients will be provided with salt restricted 'dialysis friendly' meals and compared to a control arm receiving usual care.
- Trial name
- PEPPERDISH (NCT03990311)
- Testing
- Sodium Restricted Meals, Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tufts Medical Center
Hepatitis B, ESRD (End Stage Renal Disease)
Comparing Hepatitis B Vaccination Schedules in Patients on Hemodialysis
People with kidney failure who are on dialysis have a weaker immune response to the hepatitis B vaccine than healthy people. Even after vaccination, many dialysis patients do not develop enough protection against hepatitis B…
- Conditions
- Hepatitis B, ESRD (End Stage Renal Disease), Kidney Failure, Chronic
- Trial name
- 3v4-HEP-DOSE (NCT07784452)
- Testing
- Recombinant Hepatitis B Vaccine - 3-Dose Schedule, Recombinant Hepatitis B Vaccine - 4-Dose Schedule
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- Jinnah Hospital
Tunnelled Hemodialysis Catheter Infection
Evaluation of the Efficacy of an inTerdialytic "Ethanol 40% v/v - enoxapaRin 1000 U/mL" Lock solutioN to Prevent Tunnelled Catheter Infections in Chronic Hemodialysis Patients
The purpose of this study is to assessed the efficacy of a combined solution of ethanol (4%) and low molecular weight heparins LMWH in preventing tunnelled dialysis catheter infection in chronic hemodialysis patients
- Trial name
- ETERNITY (NCT03083184)
- Testing
- Ethanol, enoxaparin
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hemodialysis, End Stage Renal Disease
Effects of Omega 3 in Hemodialysis Patients
The aim of the study was to determine the effects of a 3-week fish oil oral supplementation on the metabolic fate and thermogenic effect of an oral glucose load in hemodialysis patients.
- Trial name
- NCT00431899
- Testing
- fish oil supplementation
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Laboratoire Régional de Nutrition Humaine
Haemodialysis Patients
Studying Thyroid Function of Haemodialysis Patients in Upper Egypt (Two Centers Study).
1. The study aims to investigate the prevalence of thyroid dysfunction in haemodialysis patients and study the association of thyroid hormone concentration with health status of those patients 2.
- Trial name
- NCT06500663
- Testing
- haemodialysis
- Volunteers
- 160 people
- Sponsor
- Sahar Ezeldeen Hussein Ali
Inflammation, End-stage Renal Disease
Use of Telmisartan and Captopril in Inflammation of Hemodialysis Patients
The aim of this study was to compare the dual use of telmisartan and captopril vs the individual use of such drugs and placebo on the systemic inflammation of patients on hemodialysis (HD).
- Trial name
- NCT01271478
- Testing
- Telmisartan plus Captopril
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Hemodialysis
A Clinical Study on the Impact of Hemoperfusion on the Prognosis of Uremic Patients Undergoing Maintenance Hemodialysis
The goal of this real-world clinical trial study is to evaluate the impact of hemoperfusion on the prognosis of patients with End-Stage Renal Disease (ESRD) undergoing maintenance hemodialysis.
- Trial name
- NCT06981559
- Volunteers
- 162 people
- Sponsor
- xujiao chen
End Stage Renal Disease, Hemodialysis
Sevelamer Hydrochloride and Femoral and Carotid Intima Media Thickness Progression in End Stage Renal Disease
Aims of the multi-center, randomized, treatment-controlled clinical trial are to compare the efficacy of sevelamer hydrochloride to calcium-containing phosphorus binders in reducing the rate of progression of femoral and carotid…
- Conditions
- End Stage Renal Disease, Hemodialysis, Intimal Media Thickness
- Trial name
- SUMMER (NCT01049815)
- Testing
- sevelamer hydrochloride, Calcium Carbonate
- Where
- 2 sites in Israel
- Volunteers
- 175 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Inflammation, Oxidative Stress
The Influence of Cessation of Pomegranate Juice Intake on Inflammation and Oxidative Stress Markers and Glucose Control in Diabetic and Non Diabetic Chronic Hemodialysis Patients
The current study will investigate chronic hemodialysis patients who were treated in our unit with pomegranate juice intake for 1 year - compared to a control group.
- Trial name
- NCT01033435
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 49 people
- Sponsor
- Western Galilee Hospital-Nahariya
Kidney Failure, Hemodialysis
SGLT2 Inhibition in Hemodialysis
Dapagliflozin will be compared with placebo to evaluate its effects on cardiac structure and safety in patients with kidney failure receiving maintenance hemodialysis.
- Conditions
- Kidney Failure, Hemodialysis, Diabetes Mellitus, Type 2, Chronic Kidney Disease
- Trial name
- DAPA-HD (NCT05179668)
- Testing
- Dapagliflozin 10 MG
- Where
- 9 sites in Austria
- Volunteers
- 220 people
- Sponsor
- Medical University of Vienna
Interventional
Clinical, Psychosocial, and Comfort Effects of Hybrid Education in Hemodialysis Patients: A Randomized Controlled Trial
The purpose of this study is to evaluate the impact of a self-care and self-efficacy-based hybrid education program implemented for individuals receiving hemodialysis treatment on their clinical findings, psychosocial status…
- Trial name
- NCT07095491
- Testing
- Experimental, Control
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Mersin University
Anticoagulation in Dialysis Patients
Comparison of Point of Care to Lab INR in Dialysis Patients on Warfarin
To determine whether point of care (POC) International Normalized Ratio (INR) test results correlate with plasma INR measures in hemodialysis patients.
- Trial name
- NCT00660946
- Volunteers
- 37 people
- Sponsor
- Mayo Clinic
Anemia, Kidney Failure, Chronic
A Phase 2 Study of Intravenous or Subcutaneous Dosing of Sotatercept (ACE-011) in Patients With End-Stage Kidney Disease on Hemodialysis
To determine the optimal route of administration, dose level, and safety of intravenous and subcutaneous dosing of sotatercept for maintaining hemoglobin levels in subjects who are on hemodialysis.
- Trial name
- NCT01999582
- Testing
- Sotatercept
- Where
- 23 sites in Belgium, Germany and 3 more
- Volunteers
- 50 people
- Sponsor
- Celgene
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