Clinical trials: Hemodialysis Patients
Secondary Hyperparathyroidism, Renal Insufficiency, Chronic
Effectiveness and Safety of IV Zemplar in Patients on Hemodialysis and With Secondary Hyperparathyroidism Using iPTH/100 as Initial Dose
The purpose of this study is to observe the effectiveness and safety of the use of a low initial dose regime (iPTH/100) in chronic kidney disease patients with secondary hyperparathyroidism (PTH>300pg/mL) and that require…
- Conditions
- Secondary Hyperparathyroidism, Renal Insufficiency, Chronic, Parathyroid Hormone, Hemodialysis
- Trial name
- NCT00891813
- Testing
- Zemplar (paricalcitol)
- Where
- 3 sites in Peru
- Volunteers
- 100 people
- Sponsor
- Abbott
Chronic Kidney Disease
A Study of PRT-201 Administered Immediately After Arteriovenous Fistula Creation in Patients With Chronic Kidney Disease
The purpose of this study is to determine if PRT-201 when applied to a limited segment of your blood vessel (about 2 inches) immediately after surgery to create an arteriovenous fistula is safe and improves the patency of your…
- Trial name
- NCT01305824
- Testing
- PRT-201
- Where
- 23 sites in United States
- Volunteers
- 151 people
- Sponsor
- Proteon Therapeutics
Blood Coagulation Disorders
An Evaluation of the Pharmacokinetics and Pharmacodynamics of Oral Dabigatran Etexilate in Hemodialysis Patients
Patients with end stage renal disease carry a high risk for atrial fibrillation (AF) and require oral anticoagulant therapy for prevention of stroke. Often, the oral anticoagulant, warfarin sodium, is prescribed.
- Trial name
- NCT01590823
- Testing
- Dabigatran Etexilate 110 mg
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Acute Kidney Injury, Shock
Impact of Sodium Profiling During Haemodialysis on Haemodynamic Tolerance and Sonographic Extravascular Lung Water in Shocked Patients With Acute Kidney Injury
A study conducted to evaluate the effects of sodium profiling haemodialysis compared with conventional haemodialysis on hemodynamic tolerance and extravascular lung water in critically ill patients with AKI and shock.
- Trial name
- NCT07529990
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Fayoum University
Haemodialysis, Chronic Kidney Disease Requiring Chronic Dialysis
Lumasiran in Hyperoxalaemic Patients on Haemodialysis
This study will look at how well a drug that reduced the amount of oxalate in the body works in patients that have kidney disease and need dialysis treatment.
- Conditions
- Haemodialysis, Chronic Kidney Disease Requiring Chronic Dialysis, Cardiovascular Disease, Cardiovascular Risk Factor
- Trial name
- LHOxH (NCT06225544)
- Testing
- Lumasiran
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Hyperphosphatemia
A Phase1 Study to Explore the Safety of EOS789 in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysis
This study is a randomized study designed as a 2x2 cross-over in two periods (Period 1 and Period 2) to assess the safety, pharmacokinetics (PK), pharmacodynamics (PD), and efficacy of EOS789 in patients with chronic kidney…
- Trial name
- NCT02965053
- Testing
- EOS789, Renvela
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Chugai Pharmaceutical
Hemodialysis, Chronic Kidney Disease
Comparison of Body Hydration State in Hemodialysis Patients
Estimation of hydration state in dialysis patients is a major challenge in clinical practice. Although many methods have been studied, none have been established yet for clinical routine practice.
- Trial name
- NCT01814254
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Renal Research Institute
End Stage Renal Disease
Triferic Pediatric Pharmacokinetic Protocol
The main purpose is to determine the pharmacokinetics (PK) of Triferic iron administered intravenously in pediatric patients with chronic kidney disease on chronic hemodialysis (CKD-5HD).
- Trial name
- NCT02595437
- Testing
- Triferic
- Where
- 9 sites in United States
- Volunteers
- 22 people
- Sponsor
- Rockwell Medical Technologies, Inc.
Kidney Failure, Chronic
Oral Anticoagulation in Haemodialysis Patients
Guidelines recommend oral anticoagulation with vitamin K antagonists for atrial fibrillation whenever the CHADS2VASC score is superior or equal to 2.
- Trial name
- AVKDIAL (NCT02886962)
- Testing
- No oral anticoagulation, Oral anticoagulation with vitamin K antagonists
- Where
- 25 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Hemodialysis Patients
Switch and Maintenance Study of Intravenous Injections of R744 to Hemodialysis Patients (Phase Ⅲ Study)
This study will assess the efficacy and safety of intravenous R744 in renal anemia patients on hemodialysis.
- Trial name
- NCT00433888
- Testing
- R744
- Where
- 6 sites in Japan
- Volunteers
- 179 people
- Sponsor
- Chugai Pharmaceutical
Thromboembolism, Hemodialysis
A Comparison of Dalteparin and Tinzaparin for Prevention of Blood Clots in Hemodialysis Patients on Oral Anticoagulants Having Surgery
The purpose of this study is to better understand if either dalteparin or tinzaparin is a better drug to use in dialysis patients on blood thinners who are at high risk of developing blood clots and need surgery.
- Trial name
- NCT00260988
- Testing
- Fragmin (dalteparin), Innohep (tinzaparin)
- Where
- 2 sites in Canada
- Volunteers
- 29 people
- Sponsor
- Ottawa Hospital Research Institute
Renal Dialysis
Effects of L-carnitine Therapy on the Heart of Maintenance Hemodialysis Patients
This study is intended to be a multicenter, prospective, non-randomized, controlled real-world study. Patients receiving L-carnitine injection were included in the experimental group and the control group according to whether…
- Trial name
- NCT05673239
- Testing
- Levocarnitine Injection
- Where
- China
- Volunteers
- 1,008 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Vitamin D Deficiency
Vitamin D Status in Hemodialysis Transplant Candidates and Living Donors
Vitamin D, beyond its classical role in calcium and phosphate metabolism, is recognized as an important regulator of immune function and inflammation.
- Trial name
- NCT07409623
- Testing
- VITAMIN D LEVEL
- Where
- Iran
- Volunteers
- 552 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Iron Overload
Assessment of Iron Deposition in Major Organs of Hemodialysis Patients
The purpose of the present study is to evaluate in hemodialysis patients, who have elevated serum ferritin ( >2000ng/ml) and transferrin saturation (TSAT) >30%, iron deposition in the heart, pancreas, liver and spleen using the…
- Trial name
- NCT01169961
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Wolfson Medical Center
Latent Tuberculosis Infection, End Stage Renal Disease (ESRD)
Prevalence of Latent Tuberculosis Infection Among Hemodialysis Patients
This observational cross-sectional study aims to determine the prevalence of latent tuberculosis infection (LTBI) among patients undergoing regular hemodialysis at Sohag University Hospital, using the tuberculin skin test (TST).
- Conditions
- Latent Tuberculosis Infection, End Stage Renal Disease (ESRD), Hemodialysis
- Trial name
- NCT07210970
- Testing
- Tuberculin Skin Test (TST)
- Volunteers
- 200 people
- Sponsor
- Sohag University
Native Arteriovenous Fistula, Stenosis
Drug Eluting Balloon Venoplasty in AV Fistula Stenosis
DeVA is a single blinded, prospective, multicentre RCT designed to determine the safety and effectiveness of a drug eluting angioplasty balloon compared with a standard angioplasty balloon in patients with symptomatic native AV…
- Trial name
- DeVA (NCT02902094)
- Testing
- Drug eluting balloons, Non drug eluting balloons
- Where
- United Kingdom
- Volunteers
- 186 people
- Sponsor
- University Hospital Birmingham
Anaemia, Chronic Kidney Disease
Probiotics Against Erythropoietin Resistance in Chronic Kidney Disease Patients.
The goal of this clinical trial is to assess whether probiotic supplementation can improve the hematological response of CKD patients to erythropoietin therapy and prevent or reduce erythropoietin resistance.
- Conditions
- Anaemia, Chronic Kidney Disease, Regular Hemodialysis
- Trial name
- NCT07296146
- Testing
- Erythropoietin + Probiotic, EPO
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Badr University
Kidney Failure, Chronic, Dietary Modification
Dietary Sodium-Restriction (DIS) and Renal Meals (RM) for Hemodialysis (HD)(DISaRM-HD)
Chronic volume overload (VO) is a primary factor responsible for the excessive cardiovascular morbidity and mortality in hemodialysis (HD) patients.
- Trial name
- DISaRM-HD (NCT04991441)
- Testing
- Controlled Dietary Sodium Restriction, Control Diet & Controlled Dietary Sodium Restriction
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Illinois at Urbana-Champaign
Hyperkalemia
SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients
This study aims to compare the effects of Sodium Zirconium Cyclosilicate versus Sodium Polystyrene Sulfonate for treatment of hyperkalemia in patients undergoing regular hemodialysis.
- Trial name
- NCT06029179
- Testing
- sodium zirconium cyclosilicate (SZC), sodium polystyrene sulfonate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Fibroblast
Fibroblast Growth Factor-23 (FGF-23) is Independently Associated With Left Ventricular Mass Index (LVMI) and Myocardial Performance Index (MPI) in Haemodialysis Patients
Serum FGF-23 levels will be measured in patients with a history of coronary artery disease and aortic valve calcifications.It will be searched whether patients with MPI>0.47 had higher or lower serum FGF-23 levels than those with…
- Trial name
- NCT01154842
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Diskapi Teaching and Research Hospital
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