Clinical trials: Hemodialysis Patients
Cardiology, Nefrology
Telerehabilitation in Hemodialysis Patients.
Chronic kidney disease is the third most common cause of death, with a prevalence of 10-12%. Patients undergoing hemodialysis often exhibit low levels of physical activity, leading to various health issues, including poor quality…
- Trial name
- Teledialysis (NCT06891482)
- Testing
- Telerehabilitation
- Where
- Belgium
- Volunteers
- 46 people
- Sponsor
- Hartcentrum Hasselt
Peritoneal Dialysis Complication, Hemodialysis Complication
The Effect of Sacubitril/Valsartan on Cardiovascular Events in Dialysis Patients and Efficacy Prediction of Baseline LVEF Value
Patients with end stage renal disease (ESRD), especially after having maintenance dialysis are among the highest risk of heart failure (HF), which is the most important cause that affects survival rate and quality of life.
- Conditions
- Peritoneal Dialysis Complication, Hemodialysis Complication, Heart Failure
- Trial name
- NCT04572724
- Testing
- Sacubitril / Valsartan Oral Tablet, RAS Inhibitors
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shenzhen Second People's Hospital
Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis
Hypoxemia in Maintenance Hemodialysis Patients
Previous research has shown that many patients with kidney failure undergoing chronic hemodialysis (HD) have a very low venous oxygen concentration, which may further decrease during dialysis treatments.
- Conditions
- Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis, Kidney Failure, Chronic
- Trial name
- NCT03045796
- Testing
- Oxygen Saturation measured by WristOx
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Coronary Artery Disease, End Stage Renal Disease
Prospective Study of End Stage Renal Disease Patients With Coronary Artery Disease Treated by Oral Nicorandil
Nicorandil is potentially effective to prevent cardiovascular events in patients with coronary artery disease (CAD) receiving hemodialysis.
- Trial name
- NCT01475123
- Testing
- Nicorandil
- Where
- Japan
- Volunteers
- 268 people
- Sponsor
- Kumamoto University
End Stage Renal Disease Patients
Causes Of End Stage Renal Disease In Patients Undergoing Regular Hemodialysis
CKD is defined as kidney damage for ≥3 months, as defined by structural and or functional abnormalities of the kidney, with or without decreased GFR or GFR <60 mL/min/1.73m2 for ≥3 months, with or without kidney damage.
- Trial name
- NCT03779750
- Testing
- s.creatinine
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Hyperphosphatemia Patients on Hemodialysis
A Phase 3 Study of TS-172 in Hyperphosphatemia Patients on Hemodialysis With Phosphate Binders
A phase 3, randomized, placebo-controlled, double-blind, phosphate binder-combination study of TS-172 in hyperphosphatemia patients on hemodialysis
- Trial name
- NCT07285291
- Testing
- TS-172 20~60 mg/day
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Chronic Kidney Disease
Inulin and Protein Fermentation in Hemodialysis Patients
An important group of protein-bound uremic retention solutes originate from protein fermentation in the colon. P-cresol is a putrefaction metabolite of tyrosine. Indole is generated by fermentation of tryptophan.
- Trial name
- NCT00695513
- Testing
- BENEO synergy1
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Kidney Diseases, Pain, Procedural
Effect of 4-7-8 Breathing on AV Fistula Needle Pain in Dialysis Patients
For many hemodialysis patients, needle insertion into the vascular access site (fistula) is a significant source of pain and anxiety.
- Conditions
- Chronic Kidney Diseases, Pain, Procedural, Arteriovenous Fistula
- Trial name
- NCT07700680
- Testing
- Breathing technique
- Volunteers
- 80 people
- Sponsor
- Izmir Kavram Vocational School
End-stage Renal Disease, Cardiovascular Disease
Pharmacokinetics of Single-Dose Oral Ranolazine in Hemodialysis Patients
End-stage renal disease (ESRD) patients often develop cardiovascular complications, and cardiovascular disease is the leading cause of death in this population.
- Trial name
- NCT01435174
- Testing
- Ranolazine, Pharmacokinetic Blood and Dialysate Sampling, QT Interval
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Michigan
Rhabdomyolysis, Renal Failure
Myoglobin Removal by High Cut-off CVVHD
A high cut-off dialyzer (septeX) is tested for the removal of myoglobin which is not efficiently removed by standard high flux dialysis membranes.
- Trial name
- HicoRhabdo (NCT01467180)
- Testing
- septeX, HF CVVH
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Vantive Health LLC
End-Stage Renal Disease Requiring Haemodialysis, Mobile Application
Evaluation of the Effectiveness of a Mobile Application Developed for Hemodialysis Patients.
This study aims to evaluate the effectiveness of a mobile health application developed for adult patients undergoing hemodialysis treatment.
- Trial name
- NCT07211100
- Testing
- Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Saglik Bilimleri Universitesi
End Stage Renal Disease
The Benefit of Оn-Line High Convection Volume Hemodiafiltration Treatment Versus High Flow Dialysis on Reduction of Oxidative Stress and Health Related Quality of Life in Dialysis Patients
Introduction: Patients with end stage renal disease are exposed to metabolic and hemodynamic complications due to the disease itself and as a result of the dialysis treatment related complications.
- Trial name
- NCT02673099
- Testing
- HDF online
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Western Galilee Hospital-Nahariya
Diabetes Mellitus, Renal Failure
The Effects of Hemodialysis on Serum Sclerostin Levels
Background: Parathyroid hormone (PTH) and 1,25-dihydroxy vitamin D (1,25-OHD) as well as mineral bone metabolism modulators like sclerostin are thought to play an important role in in diabetic patients with chronic renal failure.
- Conditions
- Diabetes Mellitus, Renal Failure, Hemodialysis Access Failure
- Trial name
- sclerostin (NCT03952819)
- Testing
- serum sclerostin
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Hemodialysis, Diabetes
Analysis of Influencing Factors of Hypotension in Diabetic Patients Undergoing Dialysis
Hypotension (IDH) during dialysis is a common complication in hemodialysis, and the incidence is 20-50% in hemodialysis patients, the proportion of diabetic patients with IDH is 26.7%, which is much higher than that of…
- Trial name
- NCT05325892
- Testing
- This is an observational study
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Friendship Hospital
Metabolic Disorder, End Stage Renal Disease
Rheopheresis as Adjuvant Treatment of Calciphylaxis
The investigators propose to set up a prospective randomized controlled trial to control the security and assess the efficacy of adjuvant treatment by rheopheresis in necrotizing-ulcered calciphylaxis in the hemodialysis…
- Conditions
- Metabolic Disorder, End Stage Renal Disease, Rare Diseases
- Trial name
- RHEO-CAL (NCT04654000)
- Testing
- Rheopheresis procedure
- Where
- 29 sites in France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Lille
Hemodialysis Patient, Dry Weight
VEXUS and Assessment of Dry Weight of Patients on Hemodialysis
This is a prospective, single-arm study that will be conducted over a period of 24 weeks. The same maintenance HD patients will be followed sequentially in two study phases, with each patient serving as their own control.
- Trial name
- NCT07721636
- Testing
- ULTRASOUND for volume assessment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Hemodialysis Complication
The Effect of Patient Education Based on Nursing Model on Life Activities and Self-Care of Hemodialysis Patients
Chronic Renal Failure (CRF); The result of a decrease in the glomerular filtration value is defined as a chronic and progressive deterioration in the fluid-solute balance of the kidney and metabolic-endocrine functions.
- Trial name
- NCT04797234
- Testing
- Control, Experiment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Hyperparathyroidism, Secondary
The Study of Efficacy and Safety of REGPARA Drug in Dialysis Patients Have High Blood Levels of Parathyroid
The dialysis patient of chronic kidney disease and parathyroid hormone levels greater than or equal to 800 Pg per ml were divided into two groups by randomized 1:1, one group to receive medication and a control group that did not…
- Trial name
- NCT02056730
- Testing
- calcium sensing receptor agonist
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Chulalongkorn University
Restless Legs Syndrome (RLS), End-Stage Renal Disease
Effect of Intra-Dialytic Muscle Energy Technique on Restless Leg Syndrome in Hemodialysis Patients
The goal of this clinical trial is to learn if intra-dialytic Muscle Energy Technique (MET) can reduce symptoms of restless legs syndrome (RLS) in people with end-stage renal disease (ESRD) receiving maintenance hemodialysis.
- Trial name
- MET-RLS (NCT07748065)
- Testing
- Muscle Energy Technique, Routine Medical Treatment and Hemodialysis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Renal Insufficiency, Chronic
Functional Urodynamic Changes in Chronic Kidney Disease Patients and Does Insertion of Urinary Catheter Delay the Need for Kidney Dialysis
The aim of the investigators work is to describe the urodynamic results in the CKD (chronic kidney disease) grade 4 patients and to verify observations that urinary catheter may improve kidney function in those patients.
- Trial name
- NCT02731209
- Testing
- urinary catheter
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assaf Harofeh MC