Clinical trials: Hemodialysis Treatment
Pyelonephritis, Prognostic
Factors and Prognosis of Obstructive Pyelonephritis Patients
Acute obstructive pyelonephritis is a condition with a high risk of complications and may require admission to the intensive care unit.
- Trial name
- PYELO-OBS (NCT06299215)
- Where
- France
- Volunteers
- 575 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Secondary Hyperparathyroidism, End-stage Kidney Disease (ESKD)
Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-1
This study is to evaluate the efficacy and safety of PLS240 in patients with hemodialysis-dependent end stage kidney disease (ESKD) and secondary hyperparathyroidism (SHPT). The study consists of two phases.
- Trial name
- PATH-1 (NCT05832931)
- Testing
- PLS240, Open-Label Extension PLS240
- Where
- 68 sites in United States, Bulgaria and 4 more
- Volunteers
- 362 people
- Sponsor
- Pathalys Pharma
End Stage Renal Disease on Dialysis
Intradialytic Kinetics of Cardiac Biomarkers During Hemodialysis and Hemodiafiltration
This randomized, crossover study aims to investigate the intradialytic kinetics of selected cardiac biomarkers in patients with end-stage renal disease treated with dialysis.
- Trial name
- NCT06526702
- Testing
- High-flux hemodialysis, Post-dilution hemodiafiltration
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Aalborg University Hospital
Hemodialysis Access Failure
Effectiveness of Endoluminal Treatment of Autologous Arteriovenous Endovascular Fistula Failure
This study was aimed at comparing the efficacy and safety of cutting balloons versus drug-coated balloons in treating venous segment stenosis of autologous arteriovenous fistulas.This is a prospective, multi-center cohort study.
- Trial name
- NCT06493292
- Testing
- Endovascular therapy
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- RenJi Hospital
Chronic Hepatitis C, End Stage Renal Disease
Interferon Treatment for Patients With Chronic Hepatitis C and End Stage Renal Disease
The treatment response with conventional interferon alpha alone in patients with end stage renal disease and chronic hepatitis C is about 33-39%. However, the drop-out rate is 17-29.6%.
- Trial name
- NCT00172809
- Testing
- Peginterferon alfa-2a, Interferon alfa-2a
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Anaemia
Evaluation of Dose Response Relationship, Safety and Efficacy of GSK1278863 in Hemodialysis-dependent Subjects With Chronic Kidney Disease Associated Anemia
This study is intended to evaluate the dose-response relationship of GSK1278863 over the first 4 weeks of treatment and evaluate the safety and efficacy of GSK1278863 over 24 weeks to maintain hemoglobin (Hgb) level in…
- Trial name
- NCT01977482
- Testing
- GSK1278863, rhEPO
- Where
- 107 sites in United States, Australia and 14 more
- Volunteers
- 216 people
- Sponsor
- GlaxoSmithKline
End-stage Renal Disease
Efficacy Trial of Fluid Distribution Timetable
Nonadherence to fluid restriction is a significant issue among hemodialysis patients globally, with numerous adverse health outcomes.
- Trial name
- NCT05797766
- Testing
- Fluid Distribution Timetable
- Where
- Philippines
- Volunteers
- 40 people
- Sponsor
- University of Santo Tomas
Arteriovenous Fistula, Fistula
Cutting Balloon Versus Non-cutting Balloon for the Treatment of Venous Stenosis in the Fistulas of Hemodialyzed Patients
The main objective of this study is to evaluate and compare the primary patency rate at 12 months in a group of hemodialysis patients operated on by cutting balloon and in a group of hemodialysis patients operated by conventional…
- Trial name
- PREST (NCT01321866)
- Testing
- Cutting balloon angioplasty, Angioplasty
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hemodialysis, Probiotics
Effect of Probiotic and Synbiotic Administration on Nutritional Status in Hemodialysis Patients
This study aims to investigate the impact of probiotics and synbiotics on the nutritional status of patients with end-stage kidney disease (ESRD) who are undergoing hemodialysis.
- Conditions
- Hemodialysis, Probiotics, Synbiotics, Nutritional Status
- Trial name
- ProSyn-HD (NCT06891105)
- Testing
- Lactogemikan (Probiotic Supplement), Lactogemikan + Prebiotic Fiber (Synbiotic Supplement)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Erythropoietin Adverse Reaction
The Effect of Salicylate on Platelet Function in CKD (Chronic Kidney Disease) Patients Treated With Aranesp
The aim of the study is to 1. To determine whether treatment with Erythropoiesis-stimulating agents (in the form of Aranesp®) affects platelet function, and how. 2.
- Trial name
- EPOASA (NCT04330729)
- Testing
- Acetylsalicylic acid
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Hemodialysis, End Stage Kidney Disease (ESKD)
Dialysis Less Frequently in the Elderly
Many people who have kidney failure require hemodialysis treatments to stay alive. Hemodialysis is a procedure that cleans the blood of the toxins and fluids that build up when kidneys don't work.
- Trial name
- DLITE (NCT07738731)
- Testing
- Twice weekly hemodialysis, Thrice weekly hemodialysis treatment
- Where
- 11 sites in Canada
- Volunteers
- 210 people
- Sponsor
- Queen's University
Restless Legs Syndrome, End Stage Renal Disease
Effectiveness of Ropinirole and Gabapentin for the Treatment of RLS in Patients on Maintenance HD
Restless legs syndrome (RLS) is a neurologic disorder characterized by 1) an urge to move the legs, 2) uncomfortable sensations in the legs, 3) symptoms that are often worse the evening or when at rest , and 4) may be temporarily…
- Trial name
- NCT03708237
- Testing
- Ropinirole, Gabapentin
- Where
- 4 sites in Canada
- Volunteers
- 3 people
- Sponsor
- University of Alberta
Pruritis
A Study of Oral Ergocalciferol to Treat Pruritis in Hemodialysis Patients
Pruritis (itching) is common in many people with chronic renal failure on hemodialysis. There may be many different reasons for the pruritis. Efforts to treat the problem have not been very effective.
- Trial name
- CRN11 (NCT01114672)
- Testing
- 50,000 Units Ergocalciferol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Winthrop University Hospital
Malnutrition, Complication of Hemodialysis
Intradialytic Parenteral Nutrition in Hemodialysis Patients
Malnutrition is a major cause of death in chronic hemodialysis patients. Primary treatment of malnutrition in these patients is dietetic counseling, additional enteral nutrition and occasionally drug therapy.
- Trial name
- IDPNHD (NCT00501956)
- Testing
- Intradialytic Parenteral Nutrition (IDPN)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Fresenius Kabi
Anemia
A Study of Intravenous Mircera in Hemodialysis Patients With Chronic Renal Anemia
This single arm study will assess the efficacy, safety and tolerability of once-monthly administration of intravenous Mircera for the maintenance of hemoglobin levels in hemodialysis patients with chronic renal anemia.
- Trial name
- NCT00661505
- Testing
- methoxy polyethylene glycol-epoetin beta
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Hoffmann-La Roche
Cardio-renal Syndrome
Ultrafiltration Versus Medical Therapies in the Management of the Cardio Renal Syndrome
Type 2 cardio renal syndrome is defined by the occurrence or the exacerbation of a kidney failure induced by a chronic heart failure.
- Trial name
- UF-CARE (NCT02846337)
- Testing
- ULTRAFILTRATION, ENHANCED MEDICAL TREATMENT
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Hospices Civils de Lyon
Epilepsy
Effect of Haemodialysis on the Pharmacokinetics of Ezogabine/Retigabine and Its N-acetyl Metabolite
This in an open-label, single dose, fixed sequence, two treatment period study enrolling 8 patients (to obtain 6 evaluable) with end stage renal disease (ESRD) receiving haemodialysis.
- Trial name
- NCT01480609
- Testing
- Retigabine / Ezogabine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- GlaxoSmithKline
Chronic Renal Failure Related Anemia
Efficacy and Safety Study of GerEPO
The purpose of the study is to establish the equivalence of GerEpo with the standard treatment Eprex® for a treatment period of 12 weeks in patients on Hemodialysis with respect to hemoglobin response and to establish the…
- Trial name
- NCT00229099
- Testing
- GerEPO
- Where
- 32 sites in Malaysia
- Volunteers
- 270 people
- Sponsor
- Ministry of Health, Malaysia
Hemodialysis, End Stage Renal Disease (ESRD)
Exploring the Modulatory Effect of the Dialyzer Membrane Choice on Hemodialysisassociated Thromboinflammation: a Prospective Randomized Cross-over Trial
This clinical trial investigates whether the dialyzer membrane influences hemodialysis-associated thromboinflammation. Specifically, it evaluates the effects of 3 commercially available dialyzer membrane types on immune cell…
- Conditions
- Hemodialysis, End Stage Renal Disease (ESRD), Hemodialysis Treatment, Thromboinflammation
- Trial name
- CELL-ACT-MEMBR (NCT07682701)
- Testing
- Use of a polysulfone membrane, Use of an asymmetric triacetate membrane, Use of a polymethyl methacrylate membrane
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Chronic Kidney Disease, Chronic Renal Failure
A Phase 3 Study Comparing the Effects of Intravenous Epoetin Hospira and Epoetin Alfa [Epogen] (Amgen) in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin
The purpose of this study is to demonstrate therapeutic equivalence of IV Epoetin Hospira compared to IV Epogen (Amgen), based on maintenance of Hb levels and study drug dose requirements in patients treated for anemia associated…
- Trial name
- AiME - 01 (NCT01473407)
- Testing
- Epoetin Hospira, Epogen (Amgen)
- Where
- 85 sites in United States, Puerto Rico
- Volunteers
- 612 people
- Sponsor
- Pfizer