Clinical trials: Hemodynamic
Multiple Trauma, Polytrauma
Development and Internal Validation of a Multimodal Prediction Score for Early Hemodynamic Deterioration in Adult Polytrauma Patients
Severe traumatic injury involving multiple body regions (polytrauma) carries a high risk of rapid bleeding, tissue hypoperfusion, and circulatory collapse.
- Conditions
- Multiple Trauma, Polytrauma, Hemodynamic Instability, Traumatic Shock
- Trial name
- NCT07850427
- Volunteers
- 300 people
- Sponsor
- Assiut University
Hemodynamic Response
Demedetomidine and Remifentanil in Electroconvulsive Therapy (ECT)
Electroconvulsive therapy (ECT) is a treatment modality that induces therapeutic seizures through electrical stimulation for the management of certain psychiatric disorders.
- Trial name
- NCT07824817
- Testing
- Saline (0.9% NaCl), Dexmedetomidine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Inonu University
Pain, Hemodynamic Instability
The Effect of Virtual Reality Glasses on Pain Level and Hemo-Dynamic Variables After Open Heart Surgery
In this study, between 1 January 2025 - 1 June 2025, who met the inclusion and exclusion criteria, a total of 82 patients who are on the 2nd or 3rd day after the surgery and who are hospitalized in the cardiovascular surgery…
- Trial name
- Virtual (NCT05585853)
- Testing
- virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Mersin University
Fluid Responsiveness, Hemodynamics
Hemodynamic Evaluation and Fluid Response Observation Through Respiratory Maneuvers
This study evaluates whether respiratory maneuvers can induce measurable hemodynamic changes and whether these changes may be used to assess fluid responsiveness in healthy volunteers.
- Trial name
- HERO (NCT07840040)
- Testing
- Respiratory Maneuvers and Fluid Responsiveness Assessment Protocol
- Where
- Czechia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Hospital Pilsen
Interventional Radiology, Surgery
Dynamic Estimation of Cardiac Output in the Operating Room
During major surgery, it is recommended to monitor invasive arterial blood pressure and cardiac output (CO) during hemodynamic interventions (fluid challenge or vasopressors).
- Conditions
- Interventional Radiology, Surgery, General Anesthesia, Organ Failure
- Trial name
- TRIPLEFLOW (NCT04926220)
- Testing
- Trans-esophageal Doppler monitoring, MostCareUP Haemodynamic Monitor, Argos Cardiac Output (CO) Monitor
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aortic Stenosis Treated With TAVI, Sedation; Aged; Hemodynamics
High Flow Nasal Oxygenation in Transcatheter Aortic Valve Replacement Procedures. TAVR-Highflow II
Transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of patients with aortic valve disease. TAVR is a less invasive treatment compared to the conventional surgical approach through median sternotomy.
- Trial name
- NCT07059728
- Testing
- Oxygen therapy during sedation provided via high nasal cannulae (60L/min at 60% FiO2), Oxygen therapy during sedation delivered via nasal cannulae at 5L/min
- Where
- Spain
- Volunteers
- 452 people
- Sponsor
- Hospital Clinic of Barcelona
Hip Arthroplasty, Bone Cement Implantation Syndrome
Hemodynamic Effects of Bone Cement During Hip Arthroplasty Under Neuraxial Anesthesia
Hip arthroplasty is a commonly performed surgical procedure in elderly patients, particularly following proximal femoral fractures.
- Conditions
- Hip Arthroplasty, Bone Cement Implantation Syndrome, Perioperative Hemodynamic Optimization
- Trial name
- HIP-PRAM (NCT07817303)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ataturk University
ACL Injury, Hemodynamics
A Paradigm Shift in Musculoskeletal Rehabilitation Assessment After ACL Reconstruction Using Near-Infrared Spectroscopy
This study aims to establish and compare muscle haemodynamic response patterns in physically active subjects with anterior cruciate ligament (ACL) reconstruction, at different time points after surgery, against healthy controls…
- Conditions
- ACL Injury, Hemodynamics, Oxygen Consumption Based Assessment of Hemodynamics, Exercise
- Trial name
- HemoNIRS-LCA (NCT06621355)
- Testing
- Incremental Interval Test on a Cycle Ergometer
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Cerebral Perfusion, Cerebral Oxygenation
Evaluation of Cerebral Oxygenation During Orthopedic Surgeries Performed in the Beach Chair Position Under General Anesthesia
The goal of this observational study is to determine the correlation between cerebral oxygenation values measured by near-infrared spectroscopy (NIRS) and other routine monitoring parameters in patients placed in the semi-sitting…
- Conditions
- Cerebral Perfusion, Cerebral Oxygenation, Hemodynamic Monitoring, Semi-sitting Position
- Trial name
- NCT07270341
- Testing
- Near-Infrared Spectroscopy (NIRS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Akdeniz University
Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal
Effect of Remimazolam Versus Propofol Total Intravenous Anesthesia on Intraoperative Hemodynamic Stability in Patients Undergoing Thoracic or Abdominal Endovascular Aortic Repair
The purpose of this study is to compare two intravenous anesthetics, remimazolam and propofol, for their effects on intraoperative hemodynamic stability in patients undergoing thoracic or abdominal endovascular aortic repair.
- Conditions
- Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal, Intraoperative Hypotension, Hemodynamic Instability During Anesthesia
- Trial name
- NCT07806006
- Testing
- Remimazolam Besylate, propofol
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Hemodynamic Instability, Post-induction Hypotension (PIH)
Preoperative Neutrophil-to-Albumin Ratio and Post-Induction Hemodynamic Vulnerability in Major Oncologic Surgery
This prospective observational study aims to evaluate whether the preoperative neutrophil percentage-to-albumin ratio (NPAR) is associated with post-induction hemodynamic vulnerability in adult patients undergoing elective major…
- Trial name
- NCT07804706
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Femoral Arterial Sheath Removal, Stress Ball
Effect of Stress Ball Use During Femoral Arterial Sheath Removal After Coronary Angiography
This randomized controlled trial aims to evaluate the effects of stress ball use during femoral arterial sheath removal after coronary angiography on pain, anxiety, patient satisfaction, and hemodynamic parameters.
- Conditions
- Femoral Arterial Sheath Removal, Stress Ball, Pain, Anxiety
- Trial name
- NCT07808632
- Testing
- Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Mersin University
Hemodynamic Monitoring
Effect of Cardiorespiratory Changes on Carotid Flow Time During Lung Resection Surgery
Cardiorespiratory changes during lung resection surgery, even though generally well tolerated, may lead to hemodynamic compromise, reducing venous return to the heart and hence cardiac output.
- Trial name
- NCT07808749
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Valencia
Type I Chiari Malformation, Cerebral Hemodynamic
Analysis of Disturbances in Neurofluid Dynamics in Type I Chiari Malformations
A global analysis of craniospinal hemodynamics and hydrodynamics is necessary to better understand the pathophysiology of Chiari malformations.
- Conditions
- Type I Chiari Malformation, Cerebral Hemodynamic, Craniospinal Hydrodynamic, Phase Contrast MRI
- Trial name
- NEUROFLUX-C (NCT06502431)
- Testing
- phase contrast sequences
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hemodynamic Response to Laryngoscopy and Tracheal Intubation
Intravenous Magnesium Sulphate Versus Lignocaine for Attenuating Hemodynamic Responses to Laryngoscopy and Endotracheal Intubation
This study will compare intravenous magnesium sulfate with intravenous lidocaine for reducing the cardiovascular response to endotracheal intubation in adult patients undergoing general anesthesia.
- Trial name
- NCT07793955
- Testing
- Magnesium Sulphate infusion
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Lady Reading Hospital, Pakistan
High Altitude, Healthy Adult
Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in healthy individuals, who live permanently >2600m.
- Conditions
- High Altitude, Healthy Adult, Echocardiography, Pulmonary Resistance
- Trial name
- NCT07804485
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in patients with pulmonary arterial hypertension PAH, who live permanently…
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, High Altitude, Echocardiography
- Trial name
- NCT07804524
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
High Altitude, Healthy
Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy Individuals
To study the effect of a re-ascent after a one-week stay at sea level (after prior descent from 2850m) to high altitude (Quito Ecuador: 2850m) on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in healthy…
- Conditions
- High Altitude, Healthy, Healthy Adult, High Altitude Effects
- Trial name
- NCT07804589
- Testing
- Re-Ascent from sea level to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
AKI - Acute Kidney Injury, Cardiac Surgery
Urine Output Response to Fluid and Diuretic Therapy in Cardiac ICU Patients Monitored With FIZE kUO®
This prospective observational study evaluates the real-time urine output response to fluid therapy and diuretics in cardiothoracic intensive care unit (CTICU) patients monitored with the FIZE kUO® device.
- Conditions
- AKI - Acute Kidney Injury, Cardiac Surgery, Fluid Therapy, Hemodynamic Instability
- Trial name
- NCT07022314
- Testing
- FIZE kUO®
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- FIZE Medical ltd
Hemodynamics Instability, Pain After Surgery
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
The goal of this triple blinded randomized control trial is to compare the effect of magnesium sulphate on the hemodynamic response during pneumoperitoneum creation, along with its impact on postoperative pain, opioid…
- Conditions
- Hemodynamics Instability, Pain After Surgery, PONV in Laparoscopic Cholocystectomies
- Trial name
- NCT07079514
- Testing
- Magnesium
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin University