Clinical trials: Hemodynamic Changes, open to volunteers
Hemodynamic Changes
Assessment of Venous Return During Volume Expansion: a Prospective Observational Study
According to Guyton's model of venous return, the fluids that effectively increase cardiac output are those that, once administered, increase the vascular stressed volume, thereby increasing the mean systemic filling pressure…
- Trial name
- PSM-PVC-RITVEN (NCT07499388)
- Testing
- Fluid challenge of 500ml of crystalloid
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Università Politecnica delle Marche
Pre-eclampsia, Pregnancy
Gestational Changes in Hemodynamics and Respiratory Mechanics in Association With Pre-Eclampsia
This study focuses on elucidating the changes of hemodynamics assessed by USCOM and respiratory mechanics assessed by impedance oscillometry (IOS) over the course of pregnancy and the postpartum period.
- Conditions
- Pre-eclampsia, Pregnancy, Post Partum
- Trial name
- TREMOFLO (NCT07695909)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Comparing 2 Techniques of iv Oxytocin Causing Hemodynamic Changes
Compare Hemodynamic Effect of Oxytocin Bolus and Infusion During Cesarean Section Under Spinal Anesthesia
Oxytocin is routinely used during a cesarean section to promote uterine contraction and prevent postpartum hemorrhage. It is typically administered immediately after delivery of the baby, either as a slow intravenous bolus…
- Trial name
- NCT07687355
- Testing
- Oxytocin bolus
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Hayatabad Medical Complex
Obesity, Obesity, Abdominal
Acupoint Catgut Embedding With Laser Acupuncture for Weight Loss in Adults With Obesity
Acupoint catgut embedding and laser acupuncture have each been studied as treatments for obesity in adults, but the two have not been evaluated in combination, and few trials have measured anthropometric, biochemical, and blood…
- Conditions
- Obesity, Obesity, Abdominal, Overweight
- Trial name
- NCT07770893
- Testing
- Acupoint catgut embedding, Active laser acupuncture, Dietary and exercise counseling
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei City Hospital
Spinal Anesthesia, Hemodynamic Changes
Effect of Patient Position on Bupivacaine Dose Requirement and Hemodynamic Stability in Spinal Anesthesia
This study compares different combinations of local anesthetic doses and patient positions during spinal anesthesia for urogenital surgery.
- Conditions
- Spinal Anesthesia, Hemodynamic Changes, Patient Positions, Bupivacaine
- Trial name
- NCT07376798
- Testing
- Bupivacaine %0.5 (hyperbaric)
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Anterior Cerebral Artery Syndrome, Anterior Cerebral Artery Stroke
Transcranial Doppler Evaluation After Endovascular Thrombectomy for Acute Ischemic Stroke (PRECISE-TCD)
Endovascular thrombectomy (EVT) improves outcomes in acute ischemic stroke caused by large vessel occlusion. Despite successful recanalization, early neurological deterioration (END) remains frequent and is associated with poor…
- Conditions
- Anterior Cerebral Artery Syndrome, Anterior Cerebral Artery Stroke, Acute Ischemic Stroke, Cardioembolic Stroke
- Trial name
- NCT07013396
- Testing
- Transcranial Doppler (TCD) examination
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Virginia Commonwealth University
Orthognathic Surgery, Trigeminocardiac Reflex
Hemodynamic Changes and Trigeminocardiac Reflex During Bimaxillary Orthognathic Surgery
This observational study aims to evaluate hemodynamic changes occurring during bimaxillary orthognathic surgery using routinely collected intraoperative monitoring data.
- Conditions
- Orthognathic Surgery, Trigeminocardiac Reflex, Hemodynamic
- Trial name
- NCT07726251
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Kırıkkale University
Laryngoscopy, Hemodynamic Changes
Effect of Nalbuphine Versus Fentanyl on Hemdoynamic Effects of Laryngoscopy
Participants will undergo routine pre-operative evaluation. An intravenous line will be placed in the recovery area. On arrival in the operating room, standard monitoring (blood pressure, heart rate, oxygen saturation, ECG…
- Trial name
- NCT07435337
- Testing
- Nalbuphine, Fentanyl
- Where
- Pakistan
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Institute of Cardiology
Stroke, Stroke with Hemiparesis
Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)
The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy…
- Conditions
- Stroke, Stroke with Hemiparesis, Stroke, Ischemic
- Trial name
- NCT06806397
- Testing
- Stimulus response task
- Where
- 2 sites in Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Hemodynamics, Cytoreductive Surgery
HIPEC Surgery and Hemodynamics
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) involves the intraoperative administration of heated chemotherapeutic agents into the abdominal cavity following cytoreductive surgery (CRS).
- Conditions
- Hemodynamics, Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
- Trial name
- NCT06922227
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Miray Gözde Özdemir
Ischemic Stroke
Reperfusion Injury After Endovascular Stroke Treatment
Endovascular stroke treatment with mechanical thrombectomy (MT) has become the standard therapy for intracranial large vessel occlusion (LVO).
- Trial name
- DYNASTROKE (NCT05273216)
- Testing
- Transcranial Duplex Sonography, Brain MRI, Blood biomarkers
- Where
- 3 sites in Austria
- Volunteers
- 600 people
- Sponsor
- Medical University of Graz
Microcirculation
The Effect of Photobiomodulation on Microvascular Blood Flow: The Role of Wavelength and Skin Temperature
The objective of this study is to assess peripheral microcirculatory hemodynamic responses to photobiomodulation in participants with normal circulation and with functional peripheral vasoconstriction, using noninvasive…
- Trial name
- PBM&MBF01 (NCT07338695)
- Testing
- Photobiomodulation - Blue Wavelength, Photobiomodulation - Near Infrared
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Afeka, The Tel-Aviv Academic College of Engineering
Cesarean Section
To Compare the Effects of Oxytocin and Carbetocin on Intraoperative Hemodynamic Changes in Cesarean Section Surgeries.
To compare the effects of oxytocin and carbetocin, used as uterotonics in elective caesarean section surgeries, in terms of intraoperative hemodynamic changes.
- Trial name
- NCT06956365
- Testing
- Group-C, Group-O
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in patients with pulmonary arterial hypertension PAH, who live permanently…
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, High Altitude, Echocardiography
- Trial name
- NCT07804524
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Hemorrhagic Stroke, Ischemic Stroke
Changes in Hemodynamic Response Following Transcranial Electrical Stimulation in Sroke Individuals
The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and…
- Conditions
- Hemorrhagic Stroke, Ischemic Stroke, Subacute Stroke, Chronic Stroke Survivors
- Trial name
- NCT07433972
- Testing
- Transcranial direct current stimulation, transcranial alternating current stimulation, Rehabilitation program
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Non-invasive Electrical Cardiometry
Prospective Evaluation of Electrical Cardiometry for Hemodynamic Monitoring in COPD Patients Admitted to the Respiratory Intensive Care Unit
This study investigates the reliability and clinical usefulness of non-invasive electrical cardiometry (ICON® device) in monitoring hemodynamic changes in COPD patients admitted to the respiratory intensive care unit (RICU).
- Trial name
- NCT07208578
- Volunteers
- 96 people
- Sponsor
- Assiut University
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of a re-ascent to high altitude (Quito Ecuador: 2850m) after a one-week stay at sea level (after prior descent from 2850m) on lung function and pulmonary resistance/reactance in patients with pulmonary…
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, High Altitude Effects, High Altitude
- Trial name
- NCT07804576
- Testing
- Re-ascent from sea level to 2850m
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Aortic Stenosis
PRessure-based Evaluation of Disease Improvement in the Course of TAVI
The goal of this prospective observational study is to learn if advanced heart pressure wave analysis (using methods called WIA and REPA) can help predict the success of the procedure and long-term recovery in adults (aged 60-90)…
- Trial name
- PREDIC-TAVI (NCT07509554)
- Testing
- Transcatheter aortic valve replacement (TAVR / TAVI)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Mehmet Akif Ersoy Educational and Training Hospital
Kidney Transplantation
Multiparametric MRI for Assessment of Changes of Renal Hemodynamics After Fistula Closure in Kidney Transplant Patients
Assessment of changes of renal hemodynamics by multiparametric MRI after closure of AVF access.
- Trial name
- FISCLO (NCT05015231)
- Testing
- Echocardiography and MRI
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Diabetes Mellitus Type 2 (T2DM)
Relationship Between Hemodynamic Changes and Cardiopulmonary Fitness in Type 2 Diabetes Mellitus Patients
Diabetes mellitus being metabolic disorder, chronic in nature, is characterized by high levels of glucose in our blood, which often lead to organ dysfunction.
- Trial name
- diabetes (NCT06842108)
- Testing
- Exercise tolerance test
- Where
- Pakistan
- Volunteers
- 162 people
- Sponsor
- Bahria University