Clinical trials: Hemodynamic Measurement
Heart Failure
Relationship Between LINQ™ Subcutaneous Impedance and Right-sided Hemodynamic Measurements
The purpose of the ReLINQuish study is to characterize the relationship between subcutaneous impedance and hemodynamic measurements in patients with heart failure.
- Trial name
- NCT03608826
- Testing
- Investigational LINQ™ HF RAMware
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Stroke Volume, Mean Arterial Pressure
Validation of Stroke Volume Measurement by a New Noninvasive Hemodynamic Monitoring System (NexFin)in Comparison to Different Invasive Procedures as Picco2, FloTrac and TEE
Main hypothesis: there is no difference between stroke volume measurements recorded by a new noninvasive finger cuff system (NexFin) and invasive hemodynamic monitoring systems as Picco2-system, FloTrac and transesophageal…
- Trial name
- VaSNex (NCT01263990)
- Testing
- NexFin
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Charite University, Berlin, Germany
Kidney Failure, Respiratory Failure
Observational Study of Blood Pressure Measurements and Continuous Dialysis
Dialysis is used to control the fluid balance and metabolic state of patients with kidney disease. Control of the metabolic state, via electrolytes, can be monitored using labs that are routinely drawn from patients undergoing…
- Conditions
- Kidney Failure, Respiratory Failure, Critical Illness, Shock
- Trial name
- NCT01286506
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Chicago
Peripherally Inserted Central Catheters, Centrally Inserted Central Catheter
Single-lumen 5Fr and Triple-lumen 6Fr PICCs Are Accurate for Hemodynamic Measurement by Transpulmonary Thermodilution.
Peripherally inserted central catheters (PICCs) are increasingly used in intensive care unit (ICU) as an alternative to centrally inserted central catheters (CICCs) for intravenous infusion.
- Conditions
- Peripherally Inserted Central Catheters, Centrally Inserted Central Catheter, Transpulmonary Thermodilution, Hemodynamic Monitoring
- Trial name
- NCT04241926
- Testing
- transpolmonary thermodilution
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Congenital Heart Diseases, Hemodynamic
Non-Invasive Shunt Quantification in Interatrial Communication
Shunt quantification in atrial septal defect (ASD) is estimated by Echocardiography-Doppler, with the pulmonary-to-systemic blood flow ratio: Qp/Qs.
- Conditions
- Congenital Heart Diseases, Hemodynamic, Cardiac Output
- Trial name
- NISQIC (NCT03437148)
- Testing
- Innocor®, Physioflow®
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hemodynamic Measure, Cognitive Performance in Healthy Volunteers
Assessing the Impact of High Theacrine Doses on Hemodynamic Measures
This project measured physiological and cognitive variables to determine the effectiveness of Theacrine (TCR) as a stimulant at doses greater than those previously tested.
- Trial name
- NCT07376564
- Testing
- Low dose theacrine, Medium dose theacrine, High dose theacrine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Titch Madzima
Pulmonary Hypertension, Pulmonary Thromboembolisms
Electrical Impedance Tomography for Assessment of Pulmonary Hypertension
Pulmonary hypertension is a serious and progressive disease that is difficult to treat and diagnose, mainly because its symptoms are nonspecific and often delay recognition. Early diagnosis is a major challenge.
- Trial name
- NCT07453017
- Testing
- Electrical Impedance Tomography (EIT), Right Heart Catheterization
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
Pre-Eclampsia
Continuous Non-invasive Hemodynamic Monitoring in Early-onset Severe Preeclampsia: a Comparison of Echocardiography, Bioreactance, and Finger Cuff Measurements
The purpose of this study is to compare the feasibility and accuracy of two methods of non-invasive hemodynamic assessments - bioreactance as assessed by non-invasive cardiac output monitoring (NICOM; Cheetah Medical) and pulse…
- Trial name
- NCT05299229
- Testing
- Echocardiogrpahy and non-invasive monitoring
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Yale University
Shock
Impact of Amount of Fluid for Circulatory Resuscitation on Renal Function in Patients in Shock
Volume resuscitation is the mainstay of treatment in most types of shock, especially in hemorrhagic and septic shock. Septic shock is a main cause of morbidity and mortality worldwide.
- Trial name
- VoluKid (NCT02666404)
- Testing
- Measurement
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- University Hospital, Basel, Switzerland
AKI - Acute Kidney Injury, Cardiac Surgery
Urine Output Response to Fluid and Diuretic Therapy in Cardiac ICU Patients Monitored With FIZE kUO®
This prospective observational study evaluates the real-time urine output response to fluid therapy and diuretics in cardiothoracic intensive care unit (CTICU) patients monitored with the FIZE kUO® device.
- Conditions
- AKI - Acute Kidney Injury, Cardiac Surgery, Fluid Therapy, Hemodynamic Instability
- Trial name
- NCT07022314
- Testing
- FIZE kUO®
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- FIZE Medical ltd
Heart Failure With Severe Tricuspid Regurgitation
TRICuspid Intervention and Invasive Hemodynamic Monitoring in Heart Failure
Tricuspid regurgitation (TR) is a severe and highly prevalent disease that leads to right-sided heart failure. The severity of TR is associated with increasing morbidity and mortality.
- Trial name
- TRIC-I-HF 2 (NCT07442903)
- Testing
- Pulmonary artery sensor system
- Where
- 2 sites in Germany
- Volunteers
- 45 people
- Sponsor
- LMU Klinikum
Pregnancy Induced Hypertension, Pregnancy Related
SD-OCT Measurement of the Human Retina in Pregnancy With Pre-existing or De Novo Hypertension and Without Hypertension
The complications of long-standing severe and acute severe elevations in systemic blood pressure (hypertension) may involve large vessels as well as smaller vessels, these latter comprising what is known as the microcirculation.
- Trial name
- NCT04286217
- Volunteers
- 155 people
- Sponsor
- University of Calgary
Health, Subjective
Thermographic Analysis of Hemodynamics Changes Through & Following Wingate Test
Remote sensing and measurements of hemodynamic changes in blood flow for Wingate Anaerobic test using a novel image processing algorithm.
- Trial name
- NCT05361876
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Hemodynamics, Central Venous Pressure
Reliability of Central Venous Pressure Measurements
The purpose of this study is to compare CVP measurements from CICCs and PICCs. The investigators will also evaluate whether or not the duration of CICC placement affects the differences in CVP measurements between the CICCs and…
- Trial name
- CVP (NCT01116973)
- Testing
- PICC
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Oklahoma
Portal Hypertension
The Effect of Probiotics (VSL) on Portal Hypertension
The investigators will address the hypothesis that portal hypertension is mediated in part by bacterial or endotoxin translocation and the production of inflammatory mediators (tumor necrosis factor-α (TNFα), etc.).
- Trial name
- NCT01032941
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Accuracy and Precision of Noninvasive Measurement
CNAP Accuracy Dependent on Hemodynamic Variables
Agreement of CNAP pressure with invasive pressure is evaluated dependent on hemodynamic variables achieved by a PICCO monitor. Hypothesis: Low cardiac output and volume status but not high vascular resistance affect the accuracy…
- Trial name
- NCT01743846
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Schleswig-Holstein
Septic Shock
Comparison of Radial and Femoral Artery Site Invasive Blood Pressure Measurement in Septic Shock Patients
Inaccurate monitoring of mean arterial pressure (MAP) could lead to improper treatment in the form of excessive fluid infusion or unnecessary vasopressor therapy; therefore, accurate hemodynamic monitoring is crucial in treatment…
- Trial name
- NCT03475667
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
CHF, Renal Disease
Validation of a Sensor for Non-Invasive Measurements
Subjects will be measured with both a sensor and a reference device
- Conditions
- CHF, Renal Disease, Hypertension
- Trial name
- NCT03463148
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Baxter Healthcare Corporation
Aortic Valve Disease, Transcatheter Aortic Valve Replacement
The SAVVY Guidewire in Transcatheter Aortic Valve Replacement Procedures
TAVR patients exhibiting post-procedural residual AR had higher mortality and hospitalization rates due to heart failure, with the extent of this association increasing proportionally to the severity of the regurgitation.
- Conditions
- Aortic Valve Disease, Transcatheter Aortic Valve Replacement, Aortic Valve Stenosis, Hemodynamic Measurement
- Trial name
- SAVVY (NCT05082337)
- Testing
- SAVVY guidewire
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Hemodynamic Instability
Effect of Extended Infusion Lines on Pulse Contour-based Measurements
Hemodynamic monitoring of the critically-ill patients is increasingly performed using an arterial pulse contour-based cardiac output device such as the proAQT system.
- Trial name
- NCT03599440
- Testing
- Pressure line extensions
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares