Clinical trials: Hemodynamic Stability
Anesthesia Recovery Period ； Postoperative Pain； Hemodynamic Stability During Surgery
Afentanil and Remifentanil for Anesthesia Quality and Recovery
The goal of this clinical trial is to compare two commonly used opioid pain medications-alfentanil and remifentanil-during general anesthesia for surgery, and to find out whether alfentanil is as good as (not worse than)…
- Trial name
- NCT07761312
- Testing
- alfentanil, Remifentanil
- Volunteers
- 990 people
- Sponsor
- Qianfoshan Hospital
Steno-occlusive Disease
Effect of Dexmedetomidine on Hemodynamic Stability in Carotid Endarterectomy: Reduced Norepinephrine Use and Propofol Dosing Via Central Sympatholytic Action
1. Objective and Selection We refer to our research project as the "research project" in this information sheet. If you participate, you will be a participant.
- Trial name
- NCT07597109
- Testing
- dexmedetomidine to the standard treatment, Standard anaesthesia with propofol with co-administration of Dexmedetomidine and Propofol with Dexmedetomidine (bolus 0.4 mcg/kg over 10 minutes followed by an continuous infusion with 0.4 mcg/kg/h un
- Volunteers
- 44 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hemodynamics Instability, Anesthesia, General
Hemodynamics During Induction of General Anesthesia With High and Low Propofol Dose.
The study objective is to examine if a high propofol dose is non-inferior to a low dose in respect to hemodynamic stability in healthy patients during induction of general anesthesia with propofol and remifentanil.
- Conditions
- Hemodynamics Instability, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- PH (NCT03861364)
- Testing
- Propofol
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- Helse Fonna
Hypotension Drug-Induced, Spinal Aneshtesia
Effect of Lateral Decubitus Position After Spinal Anesthesia on Hemodynamic Stability in High-Risk Geriatric Patients
Spinal anesthesia is a common and preferred anesthetic technique for lower extremity orthopedic surgery in elderly patients. However, it can cause a significant drop in blood pressure (hypotension), especially in high-risk older…
- Conditions
- Hypotension Drug-Induced, Spinal Aneshtesia, Geriatric, Orthopedic Surgery Patients
- Trial name
- NCT07597148
- Testing
- Lateral Decubitus Positioning, Immediate Supine Positioning
- Volunteers
- 70 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Hemodynamic Instability, Postoperative Recovery
Subanesthetic Esketamine for Hemodynamic Stability and Recovery in Elderly Thoracic Surgery Patients
This retrospective study evaluated the effects of a subanesthetic dose of esketamine (0.25 mg/kg) on intraoperative hemodynamic stability and postoperative recovery quality in elderly patients (aged 65-75) undergoing thoracic…
- Conditions
- Hemodynamic Instability, Postoperative Recovery, Thoracic Surgery, Anesthesia, General
- Trial name
- NCT07064408
- Testing
- Esketamine, Normal Saline (0.9% Sodium Chloride), Midazolam
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Hebei Medical University Fourth Hospital
Airway Stress Response
Dexmedetomidine vs Labetalol for Airway Stress in Hypertensive Craniotomy Patients
This randomized trial compares dexmedetomidine and labetalol in controlling airway and hemodynamic stress during extubation in hypertensive patients undergoing craniotomy.
- Trial name
- NCT07034898
- Testing
- Dexmedetomidine, Labetalol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Cardiac Output, Low, High Blood Pressure
Assessment of Volumetric Hemodynamic Parameters and Nutritional Status in Stable Renal Transplant Recipients
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Trial name
- NCT02852941
- Testing
- CardioScreen 1000, Tanita 418- Bioelectrical impedance analysis
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Coronary Artery Disease, Stable Angina
Investigation of the Role of Hemodynamics in Re-stenosis of CABG Patients
CFD simulations in this study provide detailed hemodynamics information, which cannot be obtained from cardiac images alone. The investigators hypothesize that our proposed simulations will provide strong correlation between…
- Conditions
- Coronary Artery Disease, Stable Angina, Unstable Angina
- Trial name
- NCT02791087
- Testing
- Computed Tomography Angiography, Intra-operative graft flow rate measurement
- Where
- Singapore
- Volunteers
- 54 people
- Sponsor
- National Heart Centre Singapore
Sedation
Pharmacokinetic of Sevoflurane During a 48h Sedation in Intensive Care Unit With AnaConDa®
This is a prospective clinical monocentric study in ICU with sedated ventilated patients with sevoflurane during 48 h with the AnaConda® system, establishing pharmacokinetic model of sevoflurane.
- Trial name
- Anaconda (NCT01196754)
- Testing
- sevoflurane
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Clermont-Ferrand
Intradialytic Hypotension, Immersion
Head Out Water Immersion for Hemodynamic Stability During Dialysis
Immersion to the neck before and during hemodialysis session may increase intravascular volume, potentiate the ability to ultrafiltrate excess water, with less symptoms of shock, muscle crumps etc.
- Trial name
- NCT03057392
- Testing
- immersion
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Assaf-Harofeh Medical Center
Anesthesia, Intravenous, Hemodynamic Stability
Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery
This single-center study at CHA Ilsan Medical Center compares intraoperative hemodynamics between remimazolam- and propofol-based total intravenous anesthesia (TIVA) in patients undergoing robot-assisted gynecologic surgery…
- Conditions
- Anesthesia, Intravenous, Hemodynamic Stability, Gynecologic Surgery
- Trial name
- By_HD (NCT07251101)
- Testing
- Remimazolam, Propofol
- Where
- 2 sites in South Korea
- Volunteers
- 58 people
- Sponsor
- Ilsan Cha hospital
Tumor, Brain, Anesthesia, Local
Scalp Block: Hemodynamic Stability and Patient Comfort In Craniotomy Patients
Making sure the heart rate and or the blood pressure [called hemodynamic instability] during surgery is stable, setting up for a rapid postoperative recovery, and ensuring that patients have adequate pain relief are some of the…
- Trial name
- Scalp block (NCT03177252)
- Testing
- Lidocaine, Sodium chloride, Bupivacaine
- Sponsor
- Washington University School of Medicine
Uremic Toxins, Haemodynamic Stability
Uremic Toxin Removal and Hemodynamics in Long-hour Hemodialysis and Hemodiafiltration
Rationale: The mortality of end-stage renal disease (ESRD) patients on dialysis remains high. This may at least be partly due to the insufficient removal of (especially protein-bound) uremic toxins which have been associated with…
- Trial name
- NCT01328119
- Testing
- 4-hour HD, 4-hour HDF, 8-hour HD and 8-hour HDF
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Maastricht University Medical Center
Hemodynamic Instability, Anesthesia; Adverse Effect
Heart Failure and Hemodynamic Stability During Anesthesia Induction
The study aim is to investigate whether preoperative heart failure has impact on hemodynamic stability during anesthesia induction by target controlled infusion of anesthesia (TCI) in non-cardiac, non-morbidly obese surgery.
- Conditions
- Hemodynamic Instability, Anesthesia; Adverse Effect, Heart Failure, Diastolic Dysfunction
- Trial name
- NCT03576261
- Testing
- Preoperative colloid fluid bolus (Gelofusine), Preoperative transthoracic echocardiography
- Where
- Sweden
- Volunteers
- 44 people
- Sponsor
- Umeå University
Critical Illness
Fluid Management in Patients Undergoing Cardiac Surgery
Background: Currently used crystalloid solutes have a variable composition and may therefore influence acid-base status, intra- and extracellular water content and plasma electrolyte compositions and have a major impact on organ…
- Trial name
- Hemacetat (NCT02895659)
- Testing
- perioperative hemodynamic management with vasoactive medications (norepinephrine, adrenaline ect)
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hemodynamic Stability
Comparative Analytical Study of Intravenous Bolus Dose of Mephentermine and Phenylephrine for Hemodynamic Stability During Elective Cesarean Section Under Spinal Anesthesia at KIST Medical College and Teaching Hospital
Hemodynamics changes with spinal anesthesia is mainly due to sympathetic block which causes mainly hypotension \& bradycardia. Post spinal hypotension usually leads to various adverse maternal and fetal outcomes.
- Trial name
- NCT05706727
- Testing
- Intravenous bolus dose of Mephentermine and mephentermine, intravenous bolus dose of phenylephrine 50 mcg
- Where
- Nepal
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- KIST Medical and Teaching Hospital
Breast Cancer, Breast Surgery
Hemodynamic Effects of Intradermal Methylene Blue During Breast Surgery Under General Anesthesia
This prospective observational study aims to evaluate the effects of intradermal methylene blue injection on intraoperative hemodynamic stability in patients undergoing breast surgery under general anesthesia.
- Conditions
- Breast Cancer, Breast Surgery, Sentinel Lymph Node Biopsy, Methylene Blue
- Trial name
- NCT07040540
- Testing
- Methylene Blue, Standard Surgical Care Without Dye
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital