Clinical trials: Hemodynamic Stability, open to volunteers
Neoplasm, Cancer
Using Artificial Intelligence to Guide Fluid Therapy During Major Cancer Surgery: A Randomized Controlled Trial
The goal of this clinical trial is to learn if using artificial intelligence to guide intravenous fluid therapy during major cancer surgery can help keep blood pressure more stable compared with usual care in adult patients…
- Conditions
- Neoplasm, Cancer, Hemodynamic (MAP) Stability, Cancer Surgery
- Trial name
- FOCUS-AFM (NCT07314853)
- Testing
- Artificial Intelligence-Assisted Fluid Management, Standard fluid management
- Where
- Italy
- Volunteers
- 176 people
- Sponsor
- National Cancer Institute, Naples
Anesthesia Recovery Period ； Postoperative Pain； Hemodynamic Stability During Surgery
Afentanil and Remifentanil for Anesthesia Quality and Recovery
The goal of this clinical trial is to compare two commonly used opioid pain medications-alfentanil and remifentanil-during general anesthesia for surgery, and to find out whether alfentanil is as good as (not worse than)…
- Trial name
- NCT07761312
- Testing
- alfentanil, Remifentanil
- Volunteers
- 990 people
- Sponsor
- Qianfoshan Hospital
Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal
Effect of Remimazolam Versus Propofol Total Intravenous Anesthesia on Intraoperative Hemodynamic Stability in Patients Undergoing Thoracic or Abdominal Endovascular Aortic Repair
The purpose of this study is to compare two intravenous anesthetics, remimazolam and propofol, for their effects on intraoperative hemodynamic stability in patients undergoing thoracic or abdominal endovascular aortic repair.
- Conditions
- Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal, Intraoperative Hypotension, Hemodynamic Instability During Anesthesia
- Trial name
- NCT07806006
- Testing
- Remimazolam Besylate, propofol
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Steno-occlusive Disease
Effect of Dexmedetomidine on Hemodynamic Stability in Carotid Endarterectomy: Reduced Norepinephrine Use and Propofol Dosing Via Central Sympatholytic Action
1. Objective and Selection We refer to our research project as the "research project" in this information sheet. If you participate, you will be a participant.
- Trial name
- NCT07597109
- Testing
- dexmedetomidine to the standard treatment, Standard anaesthesia with propofol with co-administration of Dexmedetomidine and Propofol with Dexmedetomidine (bolus 0.4 mcg/kg over 10 minutes followed by an continuous infusion with 0.4 mcg/kg/h un
- Volunteers
- 44 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Blood Pressure After Nerve Block, Hemodynamic Stability During Awake Intubation
COMPARISON OF AIRWAY NERVE BLOCK VERSUS NEBULIZED LIDOCAINE ON HEMODYNAMIC RESPONSES DURING AWAKE FIBEROPTIC INTUBATION
This prospective randomized controlled trial aims to compare the effectiveness of airway nerve blocks versus nebulized lidocaine in attenuating hemodynamic responses during awake fiberoptic intubation in adult patients with…
- Trial name
- NCT07627100
- Testing
- Nebulized Lidocaine, Nerve Block
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Mayo Hospital Lahore
Airway Reactivity, Hemodynamic Stability During Anesthesia
ETCO₂ Targeting and Cerebral Oxygenation
This study looked at a safer way to prepare patients for anesthesia before major spinal surgery. Instead of using advanced or complex oxygen devices, the approach will use standard oxygen methods, guided by the patient's…
- Trial name
- NCT07526077
- Testing
- regional cerebral oxygen saturation
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- Prince Sultan Military Medical City
Ear and Nose Surgeries With Hypotensive Anaesthesia e.g FESS , MLS , TURBINECTOMY
Dexmedetomidine Versus Dexmedetomidine and Ketamine (Ketodex) in Ear and Nose Surgeries
The study aims to compare the efficacy, safety and overall effectiveness of dexmedetomidine and dexmedtomidine and ketamine (ketodex) in achieving controlled hypotension during Ear and nose surgeries.
- Trial name
- NCT06981494
- Testing
- Dexmedetomidine, Dexmedetomidine and ketamine ( Ketodex )
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Sohag University
Dental Anxiety, Postoperative Pain
Effect of Alpha-Band Binaural Beats on Stress and Recovery in Third Molar Surgery
Preoperative anxiety and loud equipment noises, such as dental drills, create significant stress and autonomic fluctuations in patients undergoing oral surgery.
- Conditions
- Dental Anxiety, Postoperative Pain, Impacted Tooth, Binaural Beats
- Trial name
- NCT07881640
- Testing
- 10 Hz Alpha-Band Binaural Beats Track, Active Noise Cancellation (ANC)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alperen Kalyoncu
Colonoscopy Procedures, Sedation
Effects of Low-Dose Ketamine Added to Propofol Sedation During Colonoscopy
"This prospective observational study aims to evaluate the effects of adding low-dose ketamine (0.25 mg/kg) to standard propofol sedation on hemodynamic stability, sedation depth, and recovery times in adult patients undergoing…
- Trial name
- NCT07809230
- Testing
- Propofol group, Propofol + Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara Etlik City Hospital
Post Induction Hypotension
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) is widely used in thoracic surgery due to small incisions, low stress response, and high patient tolerance.
- Trial name
- NCT07374458
- Testing
- Esketamine, Bilateral Lower Limb Elevation
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Hemodynamic Responses During Tracheal Extubation, Peri-extubation Hypertension
Comparative Study About The Effect Of Dexmedetomidine Vs Lignocaine On Hemodynamic Stability During Tracheal Extubation, Especially In Resource Limited Populations
This randomized, double-blind controlled trial aims to compare the effectiveness of intravenous dexmedetomidine (0.5 µg/kg) and lignocaine (1.5 mg/kg) in attenuating hemodynamic responses during tracheal extubation in adult…
- Conditions
- Hemodynamic Responses During Tracheal Extubation, Peri-extubation Hypertension, Peri-extubation Tachycardia
- Trial name
- NCT07651657
- Testing
- Tracheal Extubation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Mayo Hospital Lahore
Pre-Eclampsia
Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia
The purpose of this study is to compare the effect of albumin versus routine care on hemodynamic response and stability in pre-eclamptic patients during cesarean delivery.
- Trial name
- NCT06107335
- Testing
- Human Albumin (colloid), Lactated Ringer's Injection (crystalloid), Edwards HemoSphere monitor with ClearSight-Acumen finger cuff
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- The University of Texas Health Science Center, Houston
Brain-dead Organ Donors
Anesthesia sTrategy foR Organ Procurement In braiN dEath
The optimal anesthetic strategy during organ procurement in brain-dead donors remains unknown. The administration of anesthetic drugs in this setting aims to preserve hemodynamic stability in the face of reflex responses mediated…
- Trial name
- ATROPINE (NCT07166991)
- Testing
- Volatile anesthetic, Opioid Anesthesia, Intraoperative brain-dead donor management
- Where
- France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Grenoble
Spinal Anesthesia, Hemodynamic Changes
Effect of Patient Position on Bupivacaine Dose Requirement and Hemodynamic Stability in Spinal Anesthesia
This study compares different combinations of local anesthetic doses and patient positions during spinal anesthesia for urogenital surgery.
- Conditions
- Spinal Anesthesia, Hemodynamic Changes, Patient Positions, Bupivacaine
- Trial name
- NCT07376798
- Testing
- Bupivacaine %0.5 (hyperbaric)
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Cystoscopy
Comparison of Hemodynamic Stability With 0.75percent and 0.5percent Hyperbaric Bupivacaine During Spinal Anesthesia in Cystoscopic Procedures
Purpose:The aim of this study is to determine the intrathecal Bupivacaine concentration(0.5% vs 0.75%) with better anesthesia and little hemodynamic disturbance during cystoscopic procedures.In comparing these bupivacaine…
- Trial name
- NCT07590544
- Testing
- 0.5% Hyperbaric Bupivicaine, 0.75% hyperbaric bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- PAEC General Hospital, Islamabad
Hemodynamic (MAP) Stability, Fluid Management
Hemodynamic Optimization Using an Artificial Intelligenze System
This study will investigate the impact of using an automated fluid management system on intraoperative fluid therapy in patients undergoing colorectal surgery.
- Trial name
- SIMPLY (NCT07366164)
- Testing
- assisted fluid therapy
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Femoral Fractures, Frailty
Preoperative Oral Nutrition And Outcomes In Frail Elderly Patients With Femur Fractures
The goal of this observational study is to learn whether preoperative oral nutrition support improves clinical outcomes in elderly patients with femur fractures who have a high frailty index.
- Conditions
- Femoral Fractures, Frailty, Malnutrition
- Trial name
- NCT07463352
- Testing
- Oral Nutritional Supplement (ONS)
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people
- Sponsor
- Duzce University
Hemodynamic (MAP) Stability
Unilateral Spinal vs General Anaesthesia in Low EF Patients: A Hemodynamic Comparison
A difference exists in intraoperative hemodynamic stability and vasopressor requirement between the two techniques
- Trial name
- NCT07752303
- Testing
- Unilateral spinal anesthesia, General anesthesia
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Sargodha Medical College
Colorectal Neoplasms
DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy
This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy.
- Trial name
- NCT07239479
- Testing
- Dexmedetomidine + Desflurane, Desflurane + Normal Saline
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Tam Anh Research Institute
General Anesthesia, Aged
Remimazolam Versus Midazolam for General Anesthesia Induction in Elderly Patients Undergoing Non-Cardiac Surgery
This prospective observational cohort study evaluates the effectiveness and safety of two benzodiazepine sedatives-remimazolam and midazolam-used for general anesthesia induction in elderly patients (≥65 years) undergoing…
- Conditions
- General Anesthesia, Aged, Intraoperative Hypotension, Anxiety
- Trial name
- NCT07746505
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine