Clinical trials: Hemorrhage Brain
Critical Illness, Brain Injury
Adverse Events During Physical Therapy in Neurocritical ICU Patients
The goal of this observational study is to identify the clinical, neurological, hemodynamic, and respiratory variables associated with the occurrence of adverse events during physical therapy interventions in adult neurocritical…
- Conditions
- Critical Illness, Brain Injury, Stroke, Subarachnoid Hemorrhage
- Trial name
- NCT07901140
- Testing
- Physical Therapy Intervention
- Where
- 2 sites in Mexico
- Volunteers
- 47 people
- Sponsor
- Hospital H+ Queretaro
Hypertension, Intracranial Hemorrhage
The Efficacy and Safety of Cleviprex in Ventriculostomy Patients Requiring IV Antihypertensive Therapy
This study is a single-arm, open label protocol evaluating the use of Cleviprex to rapidly control hypertension in patients who present with intracerebral hemorrhage (ICH) or subarachnoid hemorrhage (SAH), and that require ICP…
- Conditions
- Hypertension, Intracranial Hemorrhage, Subarachnoid Hemorrhage
- Trial name
- NCT01042574
- Testing
- Clevidipine butyrate
- Where
- United States
- Sponsor
- Methodist Healthcare - Memphis
Subarachnoid Hemorrhage, Aneurysmal, Headache
Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage
The goal of this clinical trial is to learn if an infusion of lidocaine, with or without steroids, into the middle meningeal artery (MMA) helps relieve severe headaches in patients with spontaneous subarachnoid hemorrhage (SAH).
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Headache, Opiate Dependence, Opioid Use
- Trial name
- NCT07294118
- Testing
- Lidocaine, Lidocaine and Dexamethasone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Intracerebral Hemorrhage, Hemorrhagic Stroke
Haptic-Assisted Virtual Reality Upper-Limb Rehabilitation After Intracerebral Haemorrhage
After spontaneous intracerebral haemorrhage (ICH), many survivors have persistent weakness of the arm and hand. Virtual reality (VR) training with haptic (force-feedback) devices may support upper-limb recovery, but evidence…
- Conditions
- Intracerebral Hemorrhage, Hemorrhagic Stroke, Paresis
- Trial name
- CR-4-Health-VR (NCT07882810)
- Testing
- Haptic-assisted virtual reality training (Bimeo PRO), Conventional rehabilitation
- Where
- 3 sites in Austria, Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Maribor
Subarachnoid Hemorrhage, Aneurysmal
Effects of Dexmedetomidine on Inflammatory Cytokines in Patients With Aneurysmal Subarachnoid Hemorrhage
The purpose of this research is to compare patients with aneurysmal subarachnoid hemorrhage on dexmedetomidine compared to propofol to assess if one group has decreased inflammation.
- Trial name
- NCT01565590
- Testing
- Dexmedetomidine, propofol
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Cincinnati
Atrial Fibrillation
Study in Atrial Fibrillation (AF) Patients at High Risk of Stroke
The GARDENIA registry will collect real-world clinical data on the anticoagulant strategies in patients with AF at elevated risk of stroke but also elevated risk of bleeding.
- Trial name
- GARDENIA (NCT05421533)
- Where
- 96 sites in United States, Argentina and 10 more
- Volunteers
- 705 people
- Sponsor
- Anthos Therapeutics, Inc.
Myocardial Infarction, Ischemic Stroke
Understanding the Role of Autoimmune Disorders on the Initial Presentation of Cardiovascular Disease
Autoimmune diseases are diseases in which inappropriate immune responses that have the capability of harming host cells play an important role.
- Conditions
- Myocardial Infarction, Ischemic Stroke, Stroke, Subarachnoid Haemorrhage
- Trial name
- NCT02062021
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Subarachnoid Hemorrhage, Acute Kidney Injury
A Low ChloridE hyperTonic Solution for Brain Edema
This pilot study will compare the two hypertonic solutions currently used for subarachnoid hemorrhage (SAH) - related complications and to determine if the reduction of chloride load is safer, and as efficacious as the classic…
- Trial name
- ACETATE (NCT03204955)
- Testing
- Sodium chloride /sodium acetate (16.4%), Sodium chloride (23.4%), PlasmaLyte
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Emory University
Ischemic Stroke, Intracranial Hemorrhage
Registry of Acute Stroke Under New Oral Anticoagulants -Pilot (RASUNOA-Pilot)
The registry of acute stroke under new oral anticoagulants (RASUNOA) is a German multicenter, prospective, observational registry performed at about 50 study centers covering about 50.000 acute ischemic strokes and 6000 acute…
- Trial name
- RASUNOA (NCT01850797)
- Where
- Germany
- Volunteers
- 353 people
- Sponsor
- University Hospital Heidelberg
Abdominal Aortic Aneurysm, Coronary Heart Disease
Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study
Specific cardiovascular diseases, such as stroke and heart attack, have been shown to vary by ethnic group. However, less is known about differences between ethnic groups and a wider range of cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease, Sudden Cardiac Death, Intracerebral Haemorrhage
- Trial name
- NCT02176174
- Volunteers
- 1,068,318 people, healthy volunteers welcome
- Sponsor
- University College, London
Intracranial Hemorrhage
Clinical Study to Evaluate the Efficacy of Febuxostat in the Treatment of Conservatively Managed Intracranial Hemorrhage Patients
To assess the effect of Febuxostat on clinical outcomes and biomarkers of oxidative stress and inflammation in patients with conservatively managed intracranial hemorrhage.
- Trial name
- NCT07701512
- Testing
- Febuxostat 40 mg, Standard medical treatment
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Tanta University
Atrial Fibrillation, Intracerebral Hemorrhage
PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation
Atrial fibrillation (AF) is the most common form of irregular heart rhythm. In people with AF, blood clots often form in the heart, which can travel to the brain.
- Trial name
- PRESTIGE-AF (NCT03996772)
- Testing
- Apixaban Oral Tablet, Dabigatran, Edoxaban Tablets
- Where
- 64 sites in Austria, France and 4 more
- Volunteers
- 319 people
- Sponsor
- Imperial College London
Critically Ill Patients, Cardiac Surgery
Impact Of Antioxidant Micronutrients On Intensive Care Unit (ICU) Outcome
Critically ill patients are generally exposed to an increased oxidative stress, which is proportional to the severity of their condition.
- Conditions
- Critically Ill Patients, Cardiac Surgery, Trauma, Subarachnoid Hemorrhage
- Trial name
- Etude-AOX (NCT00515736)
- Testing
- Selenium (Se), Zinc (Zn), Vitamin C, Vitamin B1, Vitamin E
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Ischemic Stroke, Haemorrhagic Stroke
COAgulation Disorders in Ischaemic and Haemorrhagic Stroke
In this study the investigators will assess both procoagulant and anticoagulant pathways using thrombin generation and platelet function tests; as well as neuronal ischemia using cell free DNA in all patients presenting with…
- Conditions
- Ischemic Stroke, Haemorrhagic Stroke, Aneurysmal Subarachnoid Hemorrhage
- Trial name
- COADIHS (NCT05974111)
- Testing
- blood sampling
- Where
- Belgium
- Volunteers
- 379 people
- Sponsor
- Ziekenhuis Oost-Limburg
Subarachnoid Hemorrhage, Hypertension
Safety and Efficacy Study of Clevidipine to Control Hypertension in Patients Admitted With Aneurysmal Subarachnoid Hemorrhage
This study is designed to assess how rapidly and how safely Clevidipine can be used to control high Blood Pressure in patients with subarachnoid hemorrhage which is a type of brain bleed that happens because of a weak balloon…
- Trial name
- CLASH (NCT00978822)
- Testing
- Clevidipine butyrate injectable emulsion
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Henry Ford Health System
Intraparenchimal Cerebral Haemorrhage
Continuous Monitoring of Blood Pressure in Spontaneous Intraparenchimal Cerebral Haemorrhage
Evaluation of blood pressure variability in the acute phase of intraparenchimal cerebral haemorrhage and its consequences to clinical outcome
- Trial name
- BP-MONICH (NCT01956292)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera Sant'Anna
Intracerebral Hemorrhage
Simvastatin For Intracerebral Hemorrhage Study
Study Objective: To analyze if statins are effective in ameliorating perihematomal edema evolution thereby reducing mortality and improving functional outcomes following spontaneous intracerebral hemorrhage (ICH).
- Trial name
- NCT00718328
- Testing
- Simvastatin 80 mg
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Johns Hopkins University
Chronic Subdural Hematoma
Aspirin Continuation or Discontinuation in Conservative Treatment for Chronic Subdural Hematoma
This clinical study aims to learn about the efficacy and safety of aspirin continuation or discontinuation in conservative treatment for chronic subdural hematoma.
- Trial name
- NCT07240454
- Testing
- Aspirin Continuation, Aspirin Discontinuation
- Where
- 2 sites in China
- Volunteers
- 143 people
- Sponsor
- Tao Liu
Intraventricular Hemorrhage of Prematurity
Erythropoietin for the Repair of Cerebral Injury in Very Preterm Infants
The purpose of this randomized and placebo-controlled EpoRepair trial is to evaluate the effect of intravenously administered recombinant human erythropoietin (Epo) as compared to placebo in preterm infants with brain damage on…
- Trial name
- EpoRepair (NCT02076373)
- Testing
- recombinant human Erythropoietin
- Where
- 8 sites in Austria, Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Subarachnoid Hemorrhage, Traumatic Brain Injury
Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy
Strict glycemic control improves mortality and morbidity of patients admitted to the postoperative intensive care unit (ICU). The investigators would like to know if this therapy could improve the long term neurologic and…
- Conditions
- Subarachnoid Hemorrhage, Traumatic Brain Injury, Intracranial Hemorrhage
- Trial name
- NCT00505505
- Testing
- Insulin (Actrapid)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- University of Roma La Sapienza
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