Clinical trials: Hemorrhage Postoperative
Hemorrhage, Surgical, Hemorrhage Postoperative
Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)
Prospective, Multicenter, Double-blind, Randomized, Study to Evaluate DrugSorb-ATR Removal of Apixaban and Rivaroxaban to Reduce Likelihood of Serious Bleeding in Patients Undergoing Urgent Cardiothoracic Surgery
- Conditions
- Hemorrhage, Surgical, Hemorrhage Postoperative, Blood Loss, Surgical, Blood Loss, Postoperative
- Trial name
- STAR-D (NCT05093504)
- Testing
- DrugSorb-ATR system
- Where
- 27 sites in United States
- Volunteers
- 9 people
- Sponsor
- CytoSorbents, Inc
Pseudoaneurysm
Pseudoaneurysm of the Greater Palatine Artery Following Autogenous Connective Tissue Gingival Graft : A Case Series
Gingival recession is defined as the apical migration of the gingival margin from the amelocemental junction. This condition may be associated with symptoms such as tooth hypersensitivity, root decay, and cosmetic complaints from…
- Trial name
- NCT03454490
- Testing
- Postoperative pseudoaneurysm of the greater palatine artery
- Volunteers
- 10 people
- Sponsor
- Hopital de l'Enfant-Jesus
Abdominal Aortic Aneurysms (AAA)
Use of Artificial Intelligence to Predict Complications Following Abdominal Aortic Surgery
Abdominal aortic aneurysm, a condition characterised by an increase in the diameter of the aorta, can be treated either surgically or endovascularly.
- Trial name
- AORTAPREDICT (NCT06884397)
- Testing
- Abdominal aortic endoprosthesis
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Postoperative Hemorrhage
Fibtem Predicts Postoperative Bleeding
Retrospective study to evaluate if FIBTEM predicts the amount of postoperative bleeding in total knee replacement patients.
- Trial name
- NCT02963623
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Konkuk University Medical Center
Hip Replacement, Total
Blood-saving Effect of Combined Intravenous Tranexamic Acid With Topical Floseal® Application Total Hip Arthroplasty
Total hip arthroplasty (THA) is an excellent surgical procedure for patients with end-stage hip diseases. However, THA is associated with considerable blood loss and increasing needs for allogenic blood transfusion.
- Trial name
- NCT03623789
- Testing
- intravenous application of tranexamic acid, Floseal hemostatic matrix, Normal saline
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Hemorrhage
A Study of Fibrocaps in Liver Surgery in the Netherlands
A multi-center, prospective, randomized, single-blind, controlled, comparative efficacy and safety trial in subjects undergoing open liver resection surgery.
- Trial name
- NCT01256190
- Testing
- Fibrocaps (fibrin sealant), Gelatin sponge
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Mallinckrodt
Bleeding, Hip Fracture
How Bleeding Affects Delirium in Older Patients With Hip Fractures: The IMPROVE-HIP Study
The goal of this clinical trial is to investigate whether early detection of bleeding and prompt blood transfusions can help prevent delirium in patients aged 75 and older who are admitted to the hospital with hip fractures.
- Conditions
- Bleeding, Hip Fracture, Delirium - Postoperative
- Trial name
- NCT06938789
- Testing
- Blood Transfusion, Standard care
- Where
- 2 sites in Denmark
- Volunteers
- 198 people
- Sponsor
- University of Aarhus
Impacted Mandibular Third Molar
Comparison of Electrocautery and Scalpel Blade Incisions of Impacted Mandibular Third Molars
This randomized controlled trial aims to compare electrocautery and scalpel blade incisions during surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07723326
- Testing
- scalpel blade incision, electrocautery incision
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Riphah International University
Anterior Shoulder Instability
Tranexamic Acid for the Latarjet Procedure.
The investigators propose a double-blinded randomized study evaluating the effectiveness of tranexamic acid in reducing postoperative swelling and haematoma formation after the Latarjet procedure.
- Trial name
- NCT03458468
- Testing
- Tranexamic Acid, Saline
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- Sports Surgery Clinic, Santry, Dublin
Blood Loss, Postoperative Blood Loss
Evaluation of Intraarticular Tranexamic Acid to Reduction of Total Blood Loss Following Knee-Arthroplasty
A randomized, prospective, placebo-controlled study which aims to evaluate the effect of combined intraarticular and intravenous Tranexamic acid on total blood loss following unilateral knee replacement versus only intravenous…
- Conditions
- Blood Loss, Postoperative Blood Loss, Thromboembolic Complications
- Trial name
- NCT02427412
- Testing
- Tranexamic Acid, Saline water
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Hvidovre University Hospital
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine
Diabetic Retinopathy, Postoperative Recurrent Vitreous Hemorrhage
A Prospective Study of Ranibizumab in the Treatment of Postoperative Recurrent Vitreous Haemorrhage of Diabetic Retinopathy
Diabetic retinopathy (DR) is one of the main complications in diabetes, the proliferative diabetic retinopathy (PDR) is the most important one of the reasons leading to decreased vision, PDR is the stage of clinical intervention.
- Conditions
- Diabetic Retinopathy, Postoperative Recurrent Vitreous Hemorrhage, Pars Plana Vitrectomy, Ranibizumab
- Trial name
- NCT05248334
- Testing
- Ranibizumab Injection, PPV
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tianjin Medical University Eye Hospital
Aortic Aneurysm, Abdominal
Follow-up of Endovascular Aneurysm Treatment - The FEAT Trial
After endovascular abdominal aortic aneurysm repair, life-long follow-up is needed to monitor the effectiveness of exclusion of the aneurysm sac from blood flow.
- Trial name
- NCT00281411
- Testing
- Computed Tomography Angiography, Magnetic Resonance Angiography
- Where
- Netherlands
- Volunteers
- 46 people
- Sponsor
- Clinical Research Office Imaging Division
Pain, Postoperative, Healing Wound
Evaluation of the Effects of Medicaments Used After Free Gingival Graft on Postoperative Complications.
In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting (FGG).
- Conditions
- Pain, Postoperative, Healing Wound, Hemorrhage, Analgesia
- Trial name
- NCT05386667
- Testing
- Majezik %0.25 oral spray, Aftamed oral spray, Crystalin oral spray
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Postoperative Hemorrhage
Optimal Heparin Dosing Regimens for Cardiopulmonary Bypass
Study has been completed and is in the data analysis and manuscript writing phase of the project.
- Trial name
- Heparin Dosing (NCT00587444)
- Testing
- Heparin, HH or high heparin, heparin concentration HC
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Mayo Clinic
Ovarian Cancer
Tranexamic Acid in Surgery of Advanced Ovarian Cancer
The purpose of the study is to determine if a standardized single dose tranexamic acid given intravenously immediately preoperatively reduces the perioperative bleeding volume and reduces the need of blood transfusion in women…
- Trial name
- NCT00740116
- Testing
- Tranexamic acid, 0.9% NaCl solution
- Where
- 3 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Preben Kjolhede, MD, professor
Postoperative Bleeding
Platelet Inhibition and Bleeding in Patients Undergoing Non-Cardiac Surgery
The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing non-cardiac surgery during dual antiplatelet therapy.
- Trial name
- BIANCA (NCT01606865)
- Where
- Austria
- Volunteers
- 207 people
- Sponsor
- Medical University of Graz
Ecchymosis; Eyelid, Edema
Topical Tranexamic Acid Application in Rhinoplasty
The aim of this study is to examine the effectiveness of topical Tranexamic acid application in overcoming periorbital ecchymosis and edema after rhinoplasty, which are common and do not have a standard treatment.
- Conditions
- Ecchymosis; Eyelid, Edema, Rhinoplasty
- Trial name
- NCT05326139
- Testing
- Tranexamic acid, Isotonic saline
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Baskent University
Anticoagulant-induced Bleeding, Dental Diseases
Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy
Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral…
- Trial name
- NOADB (NCT03124030)
- Testing
- simple dental extraction
- Where
- Italy
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Bleeding, Surgical Blood Loss
Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery
The aim is to conduct a double-blinded single-centre randomized controlled clinical trial of application of topical dose of tranexamic acid (TA) versus the usual intravenous TA in patients undergoing cardiac surgery at the…
- Trial name
- DEPOSITION (NCT03376061)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 97 people
- Sponsor
- Population Health Research Institute