Clinical trials: Hemorrhoid Pain
Mixed Hemorrhoids, Milligan-Morgan Hemorrhoidectomy
Efficacy of Methylene Blue Plus Ropivacaine for Post-Hemorrhoidectomy Pain.
Revised Translation (Academic English): As one of the most prevalent anorectal disorders, mixed hemorrhoids continue to rely on the Milligan-Morgan hemorrhoidectomy as the gold-standard surgical approach.
- Conditions
- Mixed Hemorrhoids, Milligan-Morgan Hemorrhoidectomy, Methylene Blue
- Trial name
- NCT07164807
- Testing
- Methylene Blue (0.3%) with Ropivacaine Hydrochloride (0.75%), Methylene Blue (0.1%) with Ropivacaine Hydrochloride (0.75%)
- Where
- China
- Volunteers
- 177 people
- Sponsor
- The Affiliated Hospital of Putian University
Hemorrhoid Surgery, Liposome Bupivacaine
The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Hemorrhoid Surgery
Hemorrhoids represents the most prevalent condition among anorectal disorders. Due to the unique anatomical characteristics of the perianal region, patients frequently experience severe postoperative pain, which may lead some…
- Conditions
- Hemorrhoid Surgery, Liposome Bupivacaine, Pain Management, Local Infiltration
- Trial name
- NCT07442539
- Testing
- Bupivacaine hydrochloride, Liposomal bupivacaine plus bupivacaine
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital
Hemorrhoid Pain, Hemorrhoids
Topical Analgesia Post-Haemorrhoidectomy
Symptomatic haemorrhoids, or piles, have significant effects on quality of life. The treatment for advanced disease is surgical excision (haemorrhoidectomy) which is extremely effective.
- Trial name
- NCT04276298
- Testing
- Metronidazole cream, Metronidazole and Diltiazem cream, Metronidazole and Lidocaine cream
- Where
- New Zealand
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Post Hemorrhoidectomy Pain, Post Operative Pain
Ice Therapy and Warm Baths for Hemorrhoidectomy Wound Care
This study aims to compare the effectiveness of cryotherapy and warm water sitz bath in post-hemorrhoidectomy wound care. It is a prospective, randomized controlled trial that will assess the impact of these two methods on…
- Conditions
- Post Hemorrhoidectomy Pain, Post Operative Pain, Wound Heal
- Trial name
- NCT06460402
- Testing
- Ice packing, Warm sitz bath
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- E-DA Hospital
Thrombosed External Hemorrhoid
Pain Relief for Thrombosed External Haemorrhoids
Thrombosed external haemorrhoids are one of the most frequent anorectal emergencies. They are associated with swelling and intense pain.
- Trial name
- NCT00717782
- Testing
- injection of botulinum toxin, injection of saline
- Volunteers
- 30 people
- Sponsor
- University of Palermo
Hemorrhoidectomy, Hemorrhoids Third Degree
Minimally Invasive Open Excisional Hemorrhoidectomy Compared to Conventional Open Excisional Hemorrhoidectomy: a Clinical Trial
This study aims to demonstrate that open excisional hemorrhoidectomy (OEH), when performed using a minimally invasive approach, results in less postoperative pain and comparable outcomes to conventional OEH.
- Conditions
- Hemorrhoidectomy, Hemorrhoids Third Degree, Hemorrhoidal Disease, Postoperative Pain
- Trial name
- NCT06764849
- Testing
- CONVENTIONAL OPEN EXCISIONAL HEMORRHOIDECTOMY, MINIMALLY INVASIVE OPEN EXCISIONAL HEMORRHOIDECTOMY
- Sponsor
- Hospital Son Llatzer
Hemorrhoids, Fissure in Ano
Pre-Emptive Analgesia in Ano-Rectal Surgery
The perianal region is the region around the anus. Administering a pain medication before a surgery starts is called preemptive analgesia.
- Conditions
- Hemorrhoids, Fissure in Ano, Rectal Fistula, Anal Condyloma
- Trial name
- PEAARS (NCT02402543)
- Testing
- Gabapentin, Ketamine, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Vermont
Hemorrhoids, Postoperative Pain
Ultrasound-Guided Versus Landmark-Guided Pudendal Block for Post-Hemorrhoidectomy Pain
Hemorrhoid surgery is often followed by significant pain during the first few days after the operation. Pudendal nerve block is a pain-control technique that can help reduce discomfort after surgery.
- Conditions
- Hemorrhoids, Postoperative Pain, Pudendal Nerve Block
- Trial name
- NCT07889869
- Testing
- Ultrasound-Guided Pudendal Nerve Block, Landmark-Guided Pudendal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya City Hospital
Hemorrhoids, Postoperative Pain
Oral Nifedipine Versus Placebo for Pain and Healing After Hemorrhoidectomy
The goal of this clinical trial is to evaluate whether oral nifedipine reduces postoperative pain and improves wound healing after hemorrhoidectomy in adult patients aged 18-65 years undergoing elective surgery for grade III or…
- Conditions
- Hemorrhoids, Postoperative Pain, Wound Healing, Analgesia
- Trial name
- NIFEDIPINE-HD (NCT07659665)
- Testing
- Nifedipine 20 Mg
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University
Hemorrhoids
Effectiveness of Metronidazole in Pain Control Posthemorrhoidectomy
Hemorrhoidal disease occurs in 50% of people over 40 years old and is the most common cause of anorectal surgery. One of the complications of hemorrhoidectomy is pain, which is a difficult symptom to appreciate and assess, by its…
- Trial name
- NCT02328144
- Testing
- Metronidazole
- Where
- Mexico
- Volunteers
- 44 people
- Sponsor
- Instituto Mexicano del Seguro Social
Hemorrhoids, Pain
Effect of Perioperative i.v. Low-dose S(+) Ketamine
The purpose of this study is to determine whether the use of perioperative intravenous S (+) ketamine reduces the amount and degree of postoperative pain.
- Trial name
- NCT00354029
- Testing
- S (+) Ketamine
- Where
- Norway
- Volunteers
- 83 people
- Sponsor
- Asker & Baerum Hospital
Hemorrhoids
Efficacy of Lidocaine Gel Enema After Endoscopic Hemorrhoid Band Ligation for Relief of Post Procedural Pain
This is a prospective study to assess the utility of Lidocaine Hydrochloride 2% gel enema (Hi-Tech Pharmacal Co., Inc.) in reducing post-procedural pain after endoscopic band ligation of internal hemorrhoids.
- Trial name
- NCT03797703
- Testing
- Lidocaine Hydrochloride 2% gel enema
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hemorrhoid Pain, Hemorrhoidectomy
Postoperative Pain in the Surgical Treatment of Hemorrhoids: Conventional Hemorrhoidectomy With a Monopolar Electric Scaler VS Bipolar Energy With Caiman® (Aesculap®)
To demonstrate that postoperative pain secondary to Milligan and Morgan hemorrhoidectomy with Caiman® (AESCULAP®) and subsequent oral conventional analgesia is at least not greater than that generated after hemorrhoidectomy with…
- Trial name
- TAUHEMOR (NCT06535269)
- Testing
- Monopolar Hemorroidecotmy, Caiman Hemorroidectomy
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Second-degree Hemorrhoids
Comparison Between Single and Triple Rubber Band Ligation for the Treatment of Hemorrhoids
Rubber band ligation is a widely adopted treatment of internal hemorrhoids in busy coloproctology institutions. All three major hemorrhoidal clusters (left lateral, right anterior and right posterior) use to be ligated in order…
- Trial name
- NCT01383577
- Testing
- Single hemorrhoidal ligation, Triple hemorrhoidal ligation
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- Federal University of Amazonas
Hemorrhoids, Postoperative Pain
Ice Packing Versus Warm Sitz Baths After Hemorrhoidectomy
Warm sitz baths are commonly recommended after hemorrhoidectomy, although their benefit for early postoperative recovery remains uncertain. Local cold application may reduce postoperative pain and perianal swelling.
- Trial name
- NCT07843563
- Testing
- Cryotherapy (Ice Packing), Warm Sitz Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Memorial Atasehir Hospital
Hemorrhoids Second Degree, Hemorrhoids Third Degree
Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids
Hemorrhoidal disease is one of the most common anorectal disorders. Conventional Milligan Morgan Hemorrhoidectomy remains the standard treatment but is associated with considerable postoperative pain.
- Conditions
- Hemorrhoids Second Degree, Hemorrhoids Third Degree, Internal Hemorrhoids
- Trial name
- LHP-MMH (NCT07678814)
- Testing
- Laser Hemorrhoidoplasty, Milligan Morgan Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Allama Iqbal Medical College
Hemorrhoids, Postoperative Pain
Botulinum Toxin A Before Hemorrhoidectomy to Prevent Postoperative Pain
Hemorrhoidectomy is an effective surgical treatment for advanced hemorrhoidal disease but is often associated with significant postoperative pain, which may delay recovery.
- Trial name
- BoTo-HEM (NCT07399860)
- Testing
- Botulinum toxin type A, Saline (0.9% NaCl)
- Where
- Russia
- Volunteers
- 292 people
- Sponsor
- Lomonosov Moscow State University Medical Research and Educational Center
Hemorrhoids, Fissure in Ano
Measurement of Stress During Anesthesia With "Pain Detector" on Patients Receiving Atropine
24 patients randomly divided into two groups, one of the groups receiving atropine in addition to the planned anaesthesia. Skin conductance parameters to be compared between the two groups.
- Trial name
- NCT00328900
- Testing
- Administration of 0,7 mg of atropine, Measurement of skin conductance with Pain detector
- Where
- Norway
- Volunteers
- 24 people
- Sponsor
- Rikshospitalet University Hospital
Hemorrhoids
Continuous Infusion of Local Anesthetic for Optimal Post Operative Pain Control Following Hemorrhoidectomy
Over the past decade, continuous wound infiltration systems have been introduced to treat a variety of post-surgical pain. These systems, commonly referred to pain pumps by patients, possess a catheter(s) attached to a reservoir…
- Trial name
- NCT01099605
- Testing
- placement of a continuous infusion pump, continuous infusion pump of bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Hemorrhoids, Anal Fistula
Could Preoperative Assessment of Physical and Psychological Status Help Predict Pain After Anorectal Surgery?
The aim of this single-center prospective observational trial is to study the influence of physical and psychological factors on the intensity of pain syndrome after anorectal interventions and to determine the association…
- Conditions
- Hemorrhoids, Anal Fistula, Anal Fissure, Incontinence
- Trial name
- NCT06049524
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Center of Endourology "Endocenter"