Clinical trials: Hemorrhoidectomy
Hemorrhoidal Disease, Hemorrhoid Pain
Argon Plasma Coagulation in Open Excisional Hemorrhoidectomy
This prospective single-center randomized clinical trial evaluates whether the use of argon plasma coagulation (APC) during open excisional hemorrhoidectomy reduces postoperative pain and perioperative morbidity compared with…
- Conditions
- Hemorrhoidal Disease, Hemorrhoid Pain, Hemorrhoidectomy
- Trial name
- ARGO (NCT07587892)
- Testing
- open hemorrhoidectomy using argon plasma coagulation, open hemorrhoidectomy using momopolar coagulation
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Haemorrhoidal Disease, Post-operative Pain
Mesoglycan for Pain Control After Open Excisional HAEMOrrhoidectomy
Haemorrhoidal disease (HD) is the most common proctological disease, with a prevalence that can reach up to 39% of the population.
- Conditions
- Haemorrhoidal Disease, Post-operative Pain, Thrombosis
- Trial name
- MeHAEMO (NCT04481698)
- Testing
- Mesoglycan
- Where
- Italy
- Volunteers
- 398 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Acute Post Operative Pain
Various Strategies to Reduce Acute Post Hemorrhoidectomy Pain: A Comparative Study
Since post hemorrhoidectomy pain is a severe and common post operative symptom so there is a need to find a suitable method for reducing this pain, up to our knowledge, this the first study in ZUH to compare between ketrolac…
- Trial name
- NCT06307106
- Testing
- ketorolac and light marcaine, light marcaine, Corticosteroids injection
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Zagazig University
Hemorrhoid Pain, Hemorrhoids
Topical Analgesia Post-Haemorrhoidectomy
Symptomatic haemorrhoids, or piles, have significant effects on quality of life. The treatment for advanced disease is surgical excision (haemorrhoidectomy) which is extremely effective.
- Trial name
- NCT04276298
- Testing
- Metronidazole cream, Metronidazole and Diltiazem cream, Metronidazole and Lidocaine cream
- Where
- New Zealand
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Hemorrhoids Third Degree
Open Hemorrohoidectomy Vs Transanal Hemorrhoidal Desarterialization in Hemorrhoids Grade III: The Effect on Symptoms
The goal of this clinical trial is to learn if open hemorroidectomy diminishes symptoms compared to transanal hemorrhoidal desarterialization (THD) in patients presenting with hemorrhoids grade III.
- Trial name
- NCT06420986
- Testing
- Open Hemorrhoidectomy, Transanal Hemorrhoidal Dearterialization
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Son Llatzer
Postoperative Pain
Sacral Erector Spinae Plane Block Effect on Post-Hemorrhoidectomy Pain
Hemorrhoids are commonly observed surgical conditions affecting the anorectal area, characterized by symptoms such as pain, bleeding, and the presence of a protruding mass from the anal opening.
- Trial name
- NCT05965674
- Testing
- Sacral Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Konya City Hospital
Hemorrhoids, Postoperative Pain
Pudendal Nerve Block for Hemorrhoidectomy
Patients undergoing Milligan-Morgan hemorrhoidectomy will be randomized to receive or not the pudendal nerve block after the spinal anesthesia.
- Trial name
- NCT04251884
- Testing
- Local anesthetic (ropivacaine)
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- Francesco Mongelli
Hemorrhoids
Laser Hemorrhoidoplasty Versus Open Surgical Hemorrhoidectomy in Second and Third Degree Piles
The study aims to compare the pain , duration of intervention and long term outcomes of laser hemorrhoidoplasty versus open surgical hemorrhoidectomy
- Trial name
- NCT05770141
- Testing
- laser hemorrhoidoplasty, open surgical hemorrhoidectomy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemorrhoids
Local Anaesthetic Day-care Haemorrhoidectomy Challenges Traditional Concepts - a Randomised Controlled Trial
Background: Local anaesthetic day-care open haemorrhoidectomy (LH) is feasible, cheap and may be the cost-effective surgical approach to third degree haemorrhoids.
- Trial name
- NCT00503269
- Testing
- Hemorrhoidectomy
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Hemorrhoids
Ketamine for Post-operative Analgesia in Hemorrhoidectomy
This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids.
- Trial name
- NCT04248205
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
Cold Argon Plasma
Cold Argon Plasma (CAP) Application in the Wound Treatment After Open Hemorrhoidectomy
This is single-center, prospective, randomized study
- Trial name
- NCT03907306
- Testing
- Wound healing
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Postoperative Pain
Phase 2 Dose-Ranging Study of SKY0402 for Prolonged Postoperative Analgesia in Subject Undergoing Hemorrhoidectomy
Phase 2 study to evaluate three dose levels of SKY0402 compared with 75 mg of bupivacaine HCl.
- Trial name
- NCT00529126
- Testing
- SKY0402, Bupivacaine HCl
- Where
- 7 sites in United States, Georgia
- Volunteers
- 100 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Hemorrhoids
Napoleon Trial: Optimal Treatment for Recurrent Haemorrhoidal Disease
Rationale: There is level I evidence in literature that the first management step of HD is basic treatment, including laxatives and high fibre dieti, ii.
- Trial name
- NCT04101773
- Testing
- RBL versus sutured mucopexy versus haemorrhoidectomy.
- Where
- 16 sites in Netherlands
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Hemorrhoid
Endoscopic Rubber Band Ligation and Milligan-Morgan Hemorrhoidectomy for the Treatment of Grade II-III Internal Hemorrhoids: a Multicenter, Non-randomized Controlled Study
This study adopted a multicenter, non-randomized controlled clinical research design. Patients with internal hemorrhoids who met the inclusion criteria were assigned to the endoscopic rubber band ligation group (observation…
- Trial name
- NCT06794151
- Where
- China
- Volunteers
- 548 people
- Sponsor
- Weidong Tong
Hemorrhoids
Ultrasound-guided Sacral Erector Spinae Plane Block as a Sole Anesthetic Technique Versus Saddle Block in Hemorrhoidectomy
Study interventions: The patients will be randomized into two equal groups, Group A and Group B. Group A: Patients will receive an Ultrasound guided sacral erector spinae plane block (SESPB) Group B: Patients will receive Saddle…
- Trial name
- NCT06969274
- Testing
- Ultrasound guided sacral erector spinae plane block (SESPB), Saddle block.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Ligature; Hemorrhage
Haemorrhoidectomy by Ligasure and Conventional Surgery
Comparison between Haemorrhoidectomy by Ligasure and conventional surgery
- Trial name
- NCT03265990
- Testing
- ligasure haemroidectomy, Conventional haemorrhoidectomy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemorrhoids
Continuous Infusion of Local Anesthetic for Optimal Post Operative Pain Control Following Hemorrhoidectomy
Over the past decade, continuous wound infiltration systems have been introduced to treat a variety of post-surgical pain. These systems, commonly referred to pain pumps by patients, possess a catheter(s) attached to a reservoir…
- Trial name
- NCT01099605
- Testing
- placement of a continuous infusion pump, continuous infusion pump of bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Hemorrhoid
Posthemorrhoidectomy Pain Management With Electronic Bidet or Sitz Bath
The investigator will perform a randomized clinical trials to compare the effect of pain management and wound healing after hemorrhoidectomy between warm sitz bath and electronic bidet.
- Trial name
- NCT02353156
- Testing
- Electronic bidet, Sitz bath
- Volunteers
- 76 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain After Hemorrhoidectomy
Cohort Study of Auricular Acupressure for Postoperative Pain After Hemorrhoidectiomy
Auricular pressure is effective for postoperative analgesia after hemorrhoidectomy, but the evidence is not sufficient.
- Trial name
- NCT04111302
- Testing
- IV-PCA, IV-dezocine, IV-PCA+AA
- Volunteers
- 240 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Hemorrhoids
Stapled Anopexy Versus Closed Haemorrhoidectomy for Haemorrhoids
The aim of this study is to determine the role of stapled anopexy in the treatment of haemorrhoids by comparing it to the current gold standard treatment, which is excisional haemorrhoidectomy.
- Trial name
- NCT00397137
- Testing
- Circular stapled anopexy, Closed diathermy haemorrhoidectomy
- Where
- United Kingdom
- Volunteers
- 182 people
- Sponsor
- University of Dundee