Clinical trials: Hemorrhoidectomy, open to volunteers
Hemorrhoids
Ultrasound-guided Sacral Erector Spinae Plane Block as a Sole Anesthetic Technique Versus Saddle Block in Hemorrhoidectomy
Study interventions: The patients will be randomized into two equal groups, Group A and Group B. Group A: Patients will receive an Ultrasound guided sacral erector spinae plane block (SESPB) Group B: Patients will receive Saddle…
- Trial name
- NCT06969274
- Testing
- Ultrasound guided sacral erector spinae plane block (SESPB), Saddle block.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hemorrhoids, Postoperative Pain
Ultrasound-Guided Versus Landmark-Guided Pudendal Block for Post-Hemorrhoidectomy Pain
Hemorrhoid surgery is often followed by significant pain during the first few days after the operation. Pudendal nerve block is a pain-control technique that can help reduce discomfort after surgery.
- Conditions
- Hemorrhoids, Postoperative Pain, Pudendal Nerve Block
- Trial name
- NCT07889869
- Testing
- Ultrasound-Guided Pudendal Nerve Block, Landmark-Guided Pudendal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya City Hospital
Hemorrhoids
Comparison of the Clinical Effects of Open, Closed, and Semi-close Hemorrhoidectomy.
This study compares three different ways surgeons close the wound after removing hemorrhoids (piles): leaving it completely open, stitching it completely closed, or stitching only half of it closed (semi-closed).
- Trial name
- NCT07196865
- Testing
- Open Hemorrhoidectomy, Closed Hemorrhoidectomy (Ferguson Technique), Semi-Closed Hemorrhoidectomy
- Volunteers
- 378 people
- Sponsor
- The Affiliated Hospital of Putian University
Hemorrhoids
Ligasure Versus Conventional Diathermy in Hemorrhoidectomy
comparison study in the treatment of hemorrhoid between ligasure device and the conventional diathermy
- Trial name
- NCT07878546
- Testing
- ligasure
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Resting Visual Analog Scale (VAS) Pain Score
Liposomal Bupivacaine vs Ropivacaine for Post-hemorrhoidectomy Analgesia
This is a single-center, prospective, randomized, double-blind controlled trial comparing the analgesic efficacy, quality of recovery, and safety of perianal wound infiltration with multivesicular liposomal bupivacaine (266 mg)…
- Trial name
- NCT07795203
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine, Ropivacaine Hydrochloride
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Tongliao City People's Hospital
Hemorrhoidectomy, Hemorrhoid Pain
Acupuncture for Post-hemorrhoidectomy Pain Control
The goal of this clinical trial is to learn if acupuncture improves pain control after hemorrhoidectomy in patients with symptomatic hemorrhoids. It will also learn about the safety of using acupuncture in surgical patients.
- Conditions
- Hemorrhoidectomy, Hemorrhoid Pain, Acupuncture
- Trial name
- NCT07238504
- Testing
- Acupuncture
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Hemorrhoids, Postoperative Pain
Botulinum Toxin A Before Hemorrhoidectomy to Prevent Postoperative Pain
Hemorrhoidectomy is an effective surgical treatment for advanced hemorrhoidal disease but is often associated with significant postoperative pain, which may delay recovery.
- Trial name
- BoTo-HEM (NCT07399860)
- Testing
- Botulinum toxin type A, Saline (0.9% NaCl)
- Where
- Russia
- Volunteers
- 292 people
- Sponsor
- Lomonosov Moscow State University Medical Research and Educational Center
Hemorrhoids
Ketamine for Post-operative Analgesia in Hemorrhoidectomy
This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids.
- Trial name
- NCT04248205
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
Postoperative Pain, Postsurgical Pain
Sustained Release Lidocaine for the Treatment of Postoperative Pain
In this study, the investigators are testing a new formulation of lidocaine for its suitability in managing postoperative pain after pelvic (circumcision, inguinal, scrotal), perineal (hemorrhoidectomy) or perianal (fistulotomy)…
- Trial name
- NCT05193227
- Testing
- ST-01, Control (Lidocaine Hydrochloride Injection USP Xylocaine® or Bupivacaine Hydrochloride Injection USP Marcaine®)
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Hemorrhoids Internal, Hemorrhoids Second Degree
Comparing Rectal Artery Embolization and Surgery for Treatment of Bleeding Grade 2 and 3 Internal Hemorrhoids
This Phase II study will compare rectal artery embolization with operative hemorrhoidectomy in adults with symptomatic bleeding grade 2 and 3 internal hemorrhoids.
- Conditions
- Hemorrhoids Internal, Hemorrhoids Second Degree, Hemorrhoids Third Degree
- Trial name
- HemEmbo (NCT07844629)
- Testing
- Rectal Artery Embolization, Operative Hemorrhoidectomy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Colorado, Denver
Minimal Invasive Surgery, Hemorrhoidectomy
Reproducibility of a Minimally Invasive Ferguson-type Hemorrhoidectomy for Grade III Hemorrhoids
Hemorrhoids are vascular-elastic structures of the anal canal that contribute to continence. Their enlargement and descent lead to symptoms such as rectal bleeding and the sensation of anal swelling, known as hemorrhoidal…
- Trial name
- NCT07695649
- Testing
- Minimal invasive closed hemorrhoidectomy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Son Llatzer
Haemorrhoid
Traditional Ferguson Hemorrhoidectomy vs Stapled Hemorrhoidopexy
This study aimed to compare the short- and long-term outcomes of stapled hemorrhoidopexy (the procedure for prolapsed hemorrhoids, PPH) with anoplasty versus traditional Ferguson method for the treatment of patients with grade…
- Trial name
- NCT05959577
- Testing
- Stapled hemorrhoidopexy with anoplasty, Ferguson hemorrhoidectomy
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Hemorrhoid
Laser Hemorrhoidoplasty Versus Open Hemorrhoidectomy for Postoperative Pain
Hemorrhoidal disease is a common condition that can cause symptoms such as rectal bleeding and protrusion of tissue through the anal canal.
- Trial name
- NCT07846904
- Testing
- Open Milligan-Morgan Hemorrhoidectomy, Laser Hemorrhoidoplasty
- Volunteers
- 68 people
- Sponsor
- Allied Hospital Faisalabad
Mixed Hemorrhoids, Milligan-Morgan Hemorrhoidectomy
Efficacy of Methylene Blue Plus Ropivacaine for Post-Hemorrhoidectomy Pain.
Revised Translation (Academic English): As one of the most prevalent anorectal disorders, mixed hemorrhoids continue to rely on the Milligan-Morgan hemorrhoidectomy as the gold-standard surgical approach.
- Conditions
- Mixed Hemorrhoids, Milligan-Morgan Hemorrhoidectomy, Methylene Blue
- Trial name
- NCT07164807
- Testing
- Methylene Blue (0.3%) with Ropivacaine Hydrochloride (0.75%), Methylene Blue (0.1%) with Ropivacaine Hydrochloride (0.75%)
- Where
- China
- Volunteers
- 177 people
- Sponsor
- The Affiliated Hospital of Putian University
Hemorrhoid
SHAPE Versus Milligan-Morgan Hemorrhoidectomy for Hemorrhoidal Disease
This study will be conducted at the General Surgery Department, Kasr Al-Ainy Teaching Hospital, Cairo University, on patients presenting with third- and fourth-degree hemorrhoids.
- Trial name
- NCT07598630
- Testing
- Skin Sparing Hemorrhoidectomy and PExy (SHAPE), Milligan-Morgan Hemorrhoidectomy
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Hemorrhoids, Postoperative Pain
Oral Nifedipine Versus Placebo for Pain and Healing After Hemorrhoidectomy
The goal of this clinical trial is to evaluate whether oral nifedipine reduces postoperative pain and improves wound healing after hemorrhoidectomy in adult patients aged 18-65 years undergoing elective surgery for grade III or…
- Conditions
- Hemorrhoids, Postoperative Pain, Wound Healing, Analgesia
- Trial name
- NIFEDIPINE-HD (NCT07659665)
- Testing
- Nifedipine 20 Mg
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University
Hemorrhoid, Postoperative Pain
"Lignocaine vs GTN Ointment for Postoperative Pain After Hemorrhoidectomy")
This study is being conducted at the Department of General Surgery, King Edward Medical University, Lahore, Pakistan. The purpose of the trial is to compare the effectiveness of topical Lignocaine ointment versus topical Glyceryl…
- Trial name
- NCT07159334
- Testing
- Lignocaine Ointment, Glyceryl Trinitrate Ointment 0.2%
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- King Edward Medical University
Hemorrhoids, Postoperative Pain
Pudendal Nerve Block Techniques for Pain Control After Hemorrhoidectomy
Hemorrhoidectomy is frequently associated with severe postoperative pain despite multimodal analgesia. Ultrasound-guided pudendal nerve block has become an effective regional analgesic technique, but it remains unknown whether…
- Trial name
- PINPOINT (NCT07813338)
- Testing
- Transgluteal Pudendal Nerve Block, Transperineal pudendal nerve block
- Volunteers
- 140 people
- Sponsor
- Vinmec Healthcare System
Hemorrhoid, Hemorrhoidectomy
Cryotherapy for Post-Hemorrhoidectomy Pain
This prospective, patient-blinded randomized controlled trial will be conducted at Kasr Al-Ainy Hospital, Cairo University. Adult patients with grade III or IV hemorrhoids undergoing elective surgery will be randomized (1:1) to…
- Trial name
- NCT07714122
- Testing
- Milligan-Morgan Hemorrhoidectomy with Cryotherapy, Miligan-Morgan haemorroidectomy
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Cairo University
Hemorrhoidectomy, Minimally Invasive Surgical Technique
Minimaly Ivnasive Surgery for Grade III Hemorrhoids
Hemorrhoids are vascular-elastic structures of the anal canal that contribute to continence. Their enlargement and descent lead to symptoms such as rectal bleeding and the sensation of anal swelling, known as hemorrhoidal…
- Trial name
- NCT07534761
- Testing
- Minimally Invasive hemorrhoidectomy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Son Llatzer