Clinical trials: Hemorrhoids
Haemorrhoids
Randomised, Double-blind, Placebo-controlled to Assess the Efficacy and Safety of the Food Supplement Microsmin® Plus
Haemorrhoids are variceal dilatations of the anal and perianal venous plexus and often develop secondary to the persistently elevated venous pressure within the haemorrhoidal plexus .
- Trial name
- NCT05750563
- Testing
- diosmin and micronized flavonoids
- Where
- Romania
- Volunteers
- 80 people
- Sponsor
- Giellepi S.p.A
Hemorrhoids, Pregnancy
The Safety of Proctofoam-HC in the Third Trimester of Pregnancy
The purpose of this study is to evaluate the fetal safety of topical application of Proctofoam-HC®, an antihemorrhoidal, in the third trimester of pregnancy.
- Trial name
- NCT00405288
- Testing
- Proctofoam-HC®
- Where
- 2 sites in Canada
- Volunteers
- 408 people
- Sponsor
- The Hospital for Sick Children
Colorectal Cancer, Gastric Cancer
Samples Procurement for Colorectal Cancer, Gastric Cancer, and Non-malignant Disease
The purposes of this study are to collect and store samples including blood, normal and tumor tissue from patients with colorectal cancer or gastric cancer, to collect and store samples including blood and/or normal…
- Conditions
- Colorectal Cancer, Gastric Cancer, Inflammatory Bowel Diseases, Gastric Ulcer
- Trial name
- NCT03972956
- Testing
- No intervention will be given to patients.
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Renmin Hospital of Wuhan University
Hemorrhoids
HET Bipolar System: Validation of Outpatient Hemorrhoid Treatment
Purpose: The current study aims to evaluate the safety and effectiveness of the HET™ Bipolar System (Medtronic, Boulder, CO) for the treatment of grade I-II hemorrhoids in a prospective pilot study.
- Trial name
- HET (NCT02773420)
- Testing
- HET Application
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Illinois at Chicago
Piles, Bleeding
Is Doppler Necessary in Haemorrhoidal Artery Ligation Operation?
Haemorrhoidal artery ligation operation (HALO) is an operation that ties off vessels to piles. This study examines whether the ultrasound (doppler) is necessary to guide this tying off or not.
- Trial name
- NCT01051180
- Testing
- HALO
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Poole Hospital NHS Foundation Trust
Hemorrhoids
Efficacy Study of Iferanserin to Treat Hemorrhoids
To evaluate the safety and efficacy of topical 0.5% S-MPEC cream vs. placebo cream (applied twice daily for 14 days) in the treatment of Grade I - III hemorrhoids.
- Trial name
- NCT01483833
- Testing
- Iferanserin
- Where
- Germany
- Volunteers
- 121 people
- Sponsor
- Ventrus Biosciences, Inc
Hemorrhoids
Long-term Efficacy of Doppler Ligation With Mucopexy in the Treatment of Internal Hemorrhoidal Disease
A classic distinction is made between internal and external hemorrhoidal pathology. External hemorrhoids can present with thrombosis, which causes painful swelling; internal hemorrhoids by rectal bleeding, prolapse, and more…
- Trial name
- HEM_THD (NCT04708678)
- Where
- France
- Volunteers
- 151 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Hemorrhoid
Study of Pain Control in Hemorrhoidectomy
Patients will get an injection of either SKY0402 or placebo during hemorrhoid surgery, and their pain and pain medicine use will be monitored.
- Trial name
- NCT00890721
- Testing
- SKY0402
- Where
- Poland
- Volunteers
- 189 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Hemorrhoidal Disease, Cervical Cancer Radiation Complications
A Clinical Study on Alleviating Hemorrhoids-related Symptoms of Pelvic Radiation Therapy
The goal of this clinical trial is to reduce the acute hemorrhoids-related symptoms for cervical cancer patients with hemorrhoids who need postoperative pelvic radiation therapy, including prolapse, local burning, bleeding…
- Trial name
- ACS-RT (NCT07175584)
- Testing
- anal canal-sparing techniques
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Pain, Acute Post-Operative, Pilonidal Sinus
Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus Surgery
Introduction: This study investigated the efficacy of sacral erector spinae plane block (ESPB) for managing postoperative pain and reducing opioid consumption in patients undergoing hemorrhoid and pilonidal sinus (PS) surgery.
- Conditions
- Pain, Acute Post-Operative, Pilonidal Sinus, Hemorrhoids, Anesthesia
- Trial name
- NCT06459739
- Testing
- sacral ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Hemorrhoids, Open Hemorrhoidectomy
Hemorrhoids: Options of Traditional Hemorrhoidectomy
The goal of this prospective clinical trial is to compare the outcomes of several technical options of open hemorrhoidectomy in patients with symptomatic hemorrhoids.
- Trial name
- NCT06132152
- Testing
- Open hemorrhoidectomy with 'cold' scalpel, Open hemorrhoidectomy with electrosurgical scalpel
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Center of Endourology "Endocenter"
Hemorrhoids Second Degree, Traditional Chinese Medicine (TCM)
Traditional Medicine Syndromes in Internal Hemorrhoids: a Cross-Sectional Study
This study aims to investigate the characteristics of Traditional Medicine (TM) syndromes in patients diagnosed with internal hemorrhoids at Le Van Thinh Hospital.
- Trial name
- TMS-Hemorrhoid (NCT06876428)
- Volunteers
- 150 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Grade III and IV Hemorrhoids
Haemorrhoidectomy With vs Without Lateral Internal Sphincterotomy
Hemorrhoids are a common anorectal condition that often require surgical treatment in advanced stages. Open hemorrhoidectomy is effective but is frequently associated with significant postoperative pain and early bleeding.
- Trial name
- NCT07360912
- Testing
- Hemorrhoidectomy With LIS, Conventional Hemorrhoidectomy
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Baghdad
Chronic Constipation, Hemorrhoids
Clinical Efficacy and Safety Evaluation of the Drug Imescard Compound Water Smartweed Pills
The purpose of this study was to assess the clinical efficacy and safety of the drug Imescard water smartweed compound pills in the treatment of patients with chronic constipation and hemorrhoidal disease.
- Trial name
- NCT00861562
- Testing
- Imescard water smartweed composed pills
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Hemorrhoids
Prospective Randomized Trial Comparing THD Versus Stapler Operation for 3rd Degree Hemorrhoids
Haemorrhoids have, in literature, extremely high ranges of prevalence, 4,4% to 36% and there is a debate on the best treatment for III degree hemorrhoids.
- Trial name
- THD/stapler (NCT00823784)
- Testing
- Transanal doppler hemorrhoidal ligation, stapled hemorrhoidopexy
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Hemorrhoidectomy, Third Degree Hemorrhoids
Hemorrhoidectomy in Patients With Grade III and IV Disease:Harmonic Scalpel Compared With Conventional Technique
Hemorrhoidectomy is the treatment of choice for grade 3 and 4th degree hemorrhoids. Various surgical technique has been used to improve the outcome of the procedures performed in respect to operative time ,post operative pain and…
- Conditions
- Hemorrhoidectomy, Third Degree Hemorrhoids, Fourth Degree Hemorrhoids, Operative Time
- Trial name
- NCT03938714
- Testing
- Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Services Hospital, Lahore
Bleeding Anal, Pain
Topical Vitamin E Ovules for the Treatment of Hemorrhoids
Patients with hemorrohoids grade II and III were included. Patients were randomized into 2 groups: Experimental group: Patients will receive a treatment with vitamin E ovules, which must be placed inside the annus Control group…
- Conditions
- Bleeding Anal, Pain, Stings
- Trial name
- NCT04362384
- Testing
- Vitamin E ovules, Prednisolone ointment
- Volunteers
- 120 people
- Sponsor
- Hospital General Universitario Elche
Hemorrhoidectomy, Minimal Invasive Surgery
Reproducibility of Minimally Invasive Surgery for Grade III Hemorrhoids
Hemorrhoids are vascular-elastic structures of the anal canal that contribute to continence. Their enlargement and descent lead to symptoms such as rectal bleeding and the sensation of anal swelling, known as hemorrhoidal…
- Trial name
- NCT07171294
- Testing
- Minimal invasive hemorrhoidectomy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Son Llatzer
Hemorrhoids
Polidocanol Foam VS Artery Ligation in Hemorrhoidal Disease
Background: Hemorrhoidal disease is extremely frequent in the adult population and, as a benign pathology, the treatment should be guided by the patient's symptoms.
- Trial name
- NCT04675177
- Testing
- Polidocanol foam sclerotherapy, Doppler-guided hemorrhoidal artery ligation
- Where
- Portugal
- Volunteers
- 45 people
- Sponsor
- Universidade do Porto