Clinical trials: Hepatitis, Viral, Human
Chronic Hepatitis C
Pharmacogenomic Research in Korean Patients With Hepatitis C
The aim of this study is to investigate the relationships between drug response and the host genetic factors, viral factors and clinical factors in chronic hepatitis C patients (HCV).
- Trial name
- NCT01453244
- Where
- South Korea
- Volunteers
- 373 people
- Sponsor
- Inje University
Chronic Hepatitis C, End Stage Renal Disease
Interferon Treatment for Patients With Chronic Hepatitis C and End Stage Renal Disease
The treatment response with conventional interferon alpha alone in patients with end stage renal disease and chronic hepatitis C is about 33-39%. However, the drop-out rate is 17-29.6%.
- Trial name
- NCT00172809
- Testing
- Peginterferon alfa-2a, Interferon alfa-2a
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Hepatitis C, Cirrhosis
Peginterferon Alpha-2a Maintenance Therapy for Portal Hypertension in Patients With Hepatitis C
The primary purpose of this study is to determine if peginterferon alpha-2a maintenance therapy (90 mcg/week) will lower portal pressure in patients with hepatitis C virus infections and advanced fibrosis or cirrhosis.
- Conditions
- Hepatitis C, Cirrhosis, Fibrosis
- Trial name
- NCT00252642
- Testing
- Peginterferon Alpha-2a
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Virginia Commonwealth University
Chronic Hepatitis C
Real World Evidence of the Effectiveness of Paritaprevir/r - Ombitasvir, ± Dasabuvir, ± Ribavirin in Patients With Chronic Hepatitis C in Colombia
This is a prospective, multi-center observational study in adult participants chronically infected with hepatitis C virus (HCV) receiving the interferon-free ABBVIE REGIMEN (ombitasvir/paritaprevir/ritonavir with or without…
- Trial name
- outCome (NCT02851069)
- Where
- 6 sites in Colombia
- Volunteers
- 66 people
- Sponsor
- AbbVie
Hepatitis B, Chronic
Hepatitis B Patients Under Oral Nucleos(t)Ide Treatment With Intermittent Assessment of Kidney Function
Patients with chronic Hepatitis B who are under oral antiviral treatment for at least 6 months at study start will be monitored once yearly for kidney function changes within their routine outpatient visit.
- Trial name
- BONIKA (NCT02267473)
- Where
- 2 sites in Germany
- Volunteers
- 300 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Antibody Response After Vaccination
Twinrix Alternative Schedule Study
To compare the efficiency of protection against hepatitis-B virus by administration of the combined vaccine against hepatitis A and B using the schedule 0-1-12 months against the schedule 0-1-6 months. 1.
- Trial name
- NCT00216229
- Testing
- Combined vaccine against hepatitis A and B (Twinrix)
- Where
- Belgium
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- IDEWE Occupational Health Services
Rift Valley Fever
Safety/Immunogenicity/Genetic Drift of MP-12 Rift Valley Fever Vaccine
This study is to determine if a vaccine for Rift Valley Fever (RVF) is safe to give to humans. The study will examine how well the vaccine (RVF MP-12) stimulates the body's immune response (which fights off infection) and if the…
- Trial name
- MP-12 (NCT00415051)
- Testing
- RVF MP-12
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Hepatitis B, Chronic
Study IL- 35 Level and Fibronectin Type Ⅲ Domain Containing Protein 5 \ Irsin (FNDC5 rs3480) Gene Variations in Chronic Hepatitis B.
Find a possible association between Fibronectin type Ⅲ domain containing protein 5 \ Irsin (FNDC5 rs3480) gene single nucleotide polymorphism with chronic hepatitis B and the distribution of its alleles, in relation to many…
- Trial name
- NCT06023745
- Testing
- genotyping
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Porphyria Cutanea Tarda
Risk Factors of Porphyria Cutanea Tarda (PCT)
Comparison of patients with documented PCT and HCV infection, documented PCT without HCV, HCV infection without PCT and controls without HCV or PCT.
- Trial name
- NCT00213772
- Volunteers
- 280 people
- Sponsor
- University Hospital, Strasbourg, France
Chronic Hepatitis b
Plasma Purification and Chronic Hepatitis B
To compare the efficacy of nucleoside analogues （HA） alone and plasma purification +HA in reducing HBV viral load.
- Trial name
- NCT04518553
- Testing
- active comarator using antiviral drug of nucleoside analogues, HA+purification
- Volunteers
- 230 people
- Sponsor
- Shanghai Pudong Hospital
Hepatitis C, Chronic, Children, Only
Eight Weeks Sofosbovir/Ledipasvir in HCV Infected Children Aged 4 to 10 Years
Recently the era of direct-acting antiviral drugs for hepatitis C treatment has changed the world map of HCV. Results in adults are promising. FDA approved only two drugs in the pediatric age group 12 to 17 years.
- Trial name
- NCT03764345
- Testing
- Sofosbovir/Lepipasvir (200/45mg) tablet (Heterosofir)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- National Liver Institute, Egypt
Hepatitis B, Osteoporosis
Awareness of Osteoporosis in Patients With Hepatitis B Infection
Osteoporosis is a condition that describes compromised skeletal microarchitecture in general, with clinical signs of decreased bone mineral density.
- Conditions
- Hepatitis B, Osteoporosis, Osteoporosis Risk
- Trial name
- NCT05768737
- Testing
- Patient Participation Form
- Volunteers
- 400 people
- Sponsor
- Uskudar State Hospital
Hepatitis C Infection, Depression
Interaction Between Paroxetine and Telaprevir
Hepatitis C (HCV) infected patients are often in need for an antidepressant. The introduction of Direct Acting Antivirals such as telaprevir has greatly improved treatment outcome of HCV infected patients.Telaprevir has been…
- Trial name
- ROLEX (NCT01841502)
- Testing
- Paroxetine, telaprevir
- Where
- 7 sites in Netherlands
- Volunteers
- 3 people
- Sponsor
- Radboud University Medical Center
Hepatitis C, HIV Infections
Safety and Efficacy of Telaprevir in Combination With Peginterferon Alfa-2a and Ribavirin in Subjects Co-Infected With Hepatitis C Virus (HCV) and HIV
The purpose of this study is to determine whether the combination of telaprevir, peginterferon alfa-2a, and ribavirin is safe and effective in treating hepatitis C virus (HCV) infection in subjects who are infected with both HCV…
- Trial name
- NCT00983853
- Testing
- peginterferon alfa-2a, ribavirin (fixed dose), ribavirin (weight-based dose)
- Where
- 16 sites in United States, France and 2 more
- Volunteers
- 62 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Hepatitis C, Hemodialysis
Effect of HCV Infection on Insulin Resistance and Malnutrition-inflammation Complex Syndrome in Regular Hemodialysis Patients
The purpose of this study is to study whether hepatitis C virus (HCV)infected maintenance hemodialysis (MHD)patients have distinct metabolic, inflammatory and adipokine characteristics that can be linked to poor clinical outcome…
- Conditions
- Hepatitis C, Hemodialysis, Quality of Life, Mortality
- Trial name
- NCT00527774
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- St. Martin De Porress Hospital
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Hepatitis B
Clinical Performance Evaluation of DxN HBV Assay
The DxN Hepatitis B Virus (HBV) Assay is an in vitro diagnostic assay intended as an aid in the management of HBV-infected individuals undergoing antiviral therapy.
- Trial name
- NCT03123159
- Testing
- DxN HBV Assay
- Where
- 10 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Beckman Coulter, Inc.
Chronic Hepatitis B, Late Pregnancy
Study of Telbivudine and Lamivudine to Prevent Vertical Transmission of Hepatitis B
The purpose of this study is to evaluate the efficacy and safety of telbivudine and lamivudine use during late pregnancy for the prevention of HBV perinatal transmission in highly viraemic mothers.
- Conditions
- Chronic Hepatitis B, Late Pregnancy, Transmission, Complication
- Trial name
- NCT01743079
- Testing
- Telbivudine, Lamivudine
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Beijing YouAn Hospital
HCC in Chronic HCV Patients With Advanced Liver Fibrosis
Clinical Impacts of Achieving SVR in Patients With Advanced Hepatic Fibrosis Related to Chronic HCV Treated With Direct Acting Antivirals
Chronic HCV infection has relatively slow rate of progression. Liver fibrosis is the main sequlae and usually progressed to cirrhosis after long period (10 to 20 years) [6].
- Trial name
- NCT03884062
- Testing
- DAAs
- Volunteers
- 3,000 people
- Sponsor
- Egyptian Liver Hospital
Cancer, Hepatitis B
Widespread vs. Selective Screening for Hepatitis B Infection Prior to Chemotherapy
This trial studies hepatitis B screening strategies of new cancer patients scheduled to undergo chemotherapy. Patients with cancer and hepatitis B virus infection are at risk of reactivation of infection after chemotherapy.
- Conditions
- Cancer, Hepatitis B, HBV, Hepatitis B Infection
- Trial name
- NCT01970254
- Testing
- Hepatitis B Screening, Survey Administration
- Where
- United States
- Volunteers
- 2,206 people
- Sponsor
- M.D. Anderson Cancer Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.