Clinical trials: Hernia, Abdominal
Ventral Hernia
Laparoscopic Ventral Hernia Repair with Routine Defect Closure Using Su2ura® Approximation Device
Study includes 5 visits: Screening, Baseline/Surgery, and 14 days, 3 months, 12months Follow-Ups post-surgery. The actual point of enrollment for each subject is considered the day of surgery.
- Trial name
- NCT04986917
- Testing
- Hernia repair surgery using the Su2ura® approximation device, Physical Examination, Vital Signs
- Where
- 2 sites in Israel
- Volunteers
- 18 people
- Sponsor
- Anchora Medical
Inguinal Hernia, Postoperative Pain
Factors Associated With Postoperative Pain in Patients Undergoing TAPP Hernia Repair for Inguinal Hernia
The most common symptom after an inguinal hernia is postoperative pain. According to the severity of the pain, the quality of life of the patient is also affected. There are many factors associated with postoperative pain.
- Trial name
- NCT05522608
- Testing
- transabdominal preperitoneal hernia repair
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Tepecik Training and Research Hospital
Inguinal Hernia
Antalgic Efficacy of CycloMesh™ Soaked in Ropivacaine Hydrochloride in Uncomplicated Inguinal Hernia.
CycloMesh is a polyester visceral implant functionalized by drug delivery systems directly on its surface, targeting a unique intervention, a slow anesthetic release and an in situ activity.
- Trial name
- HENRI (NCT04033055)
- Testing
- Inguinal hernia repair with CycloMesh™ soaked in ropivacaine hydrochloride 10mg/mL, Inguinal hernia repair with CycloMesh™ soaked in saline solution NaCl 9°/°°
- Where
- France
- Volunteers
- 304 people
- Sponsor
- Quanta Medical
Hiatal Hernia, Hiatal Hernia With Gastroesophageal Reflux Disease
Complications of Laparoscopic Hiatal Hernia Repair Complicated by Gastroesophageal Reflux Disease Using the ERAS Protocol
Nissen fundoplication with cruroraphy performed according to ERAS protocols in patients with HH complicated by GERD.
- Trial name
- hiatal hernia (NCT07138235)
- Testing
- laparoscopic hiatal hernia repair
- Volunteers
- 106 people
- Sponsor
- Osh State University
Inguinal Hernia
M-Tapa vs OSTAP for Laparoscopic Inguinal Hernia Repair Surgery
Inguinal hernia repair is the most common of abdominal surgical procedures and is usually performed laparoscopically. Many factors play a role in the pain that develops after surgery and is generally considered to be visceral…
- Trial name
- NCT05476510
- Testing
- Postoperative management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Hernia, Hernia, Ventral
Preoptimisation in Ventral Hernia Surgery
The study is a multicentre, single-blinded, randomised controlled trial. Ventral hernia patients with an aperture width between four and eight centimetres are randomised to either participation in a multimodal preoptimisation…
- Conditions
- Hernia, Hernia, Ventral, Hernia Incisional, Hernia, Umbilical
- Trial name
- PreOpt (NCT07316426)
- Testing
- preoptimisation programme
- Where
- 5 sites in Sweden
- Volunteers
- 130 people
- Sponsor
- Umeå University
Inguinal Hernia
The Addition of Hydromorphone to Local Anesthetics for the Repair of Inguinal Hernias in Elderly Patients
To compare the clinical and postoperative analgesic effects of hydromorphone combined with ropivacaine and ropivacaine alone in quadrangular muscle block for open inguinal hernia in elderly patients.
- Trial name
- NCT06218160
- Testing
- Hydromorphone combined with ropivacaine, Ropivacaine
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Second Hospital of Jilin University
Ventral Hernia Repair
ORION Study: Mesh Position and Risk During Subsequent Minimally Invasive Abdominal Surgery
Ventral hernia repair is one of the most commonly performed abdominal surgical procedures worldwide, increasingly carried out using minimally invasive techniques.
- Trial name
- ORION (NCT07384962)
- Where
- Italy
- Volunteers
- 790 people
- Sponsor
- Istituto Auxologico Italiano
Ventral Hernia, Incisional Hernia
The Impact of Abdominal Wall Reconstruction on Abdominal Wall Tension and Intra-Abdominal Pressure
This is a prospective cohort study. Patients have an incisional or parastomal hernia with >20 cm fascial defect on pre-operative imaging who will undergo an anticipated open bilateral transversus abdominis release with…
- Conditions
- Ventral Hernia, Incisional Hernia, Parastomal Hernia
- Trial name
- NCT06575166
- Testing
- Abdominal wall tension, Intra-abdominal pressure
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Hernia, Paraesophageal Hernia
Randomized, Prospective Controlled Trial of Paraesophageal Hernia Repair With Small Intestinal Submucosa (SIS)
The purpose of this randomized study is to determine whether a type of mesh derived from a layer of pig small intestine (SIS) is of benefit in treating paraesophageal hernias versus standard surgical suture repair.
- Trial name
- NCT00272922
- Testing
- hernia repair
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Cook Group Incorporated
Ventral Hernia
3 Fixation Devices in Laparoscopic Ventral Herniotomy
Clinical, controlled, randomized, prospective study. Ventral hernias between 2(1.5)cm and 7 cm, laparoscopic surgery with intraperitoneal onlay mesh. Three randomization groups of 25 patients giving a total of 75 patients.
- Trial name
- FS (NCT01534780)
- Testing
- laparoscopic ventral herniotomy, Protack, Securestrap
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Horsens Hospital
Postoperative Pain, Acute, Ventral Hernia
Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery
The purpose of this study is to assess whether listening to music during surgery has an effect on pain or anxiety after surgery.
- Conditions
- Postoperative Pain, Acute, Ventral Hernia, Hernia Abdominal Wall, Surgery
- Trial name
- NCT05374096
- Testing
- Patient-Chosen Music
- Where
- United States
- Volunteers
- 321 people
- Sponsor
- The Cleveland Clinic
Hernia, Ventral
Robotic Versus Laparoscopic Ventral Hernia Repair
Ventral hernias are a common disease and one half of all individuals are born with or will acquire a ventral hernia in their lifetime.
- Trial name
- NCT03490266
- Testing
- Robotic Repair, Laparoscopic Repair
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pediatric Postoperative Pain
Postoperative Pain After Pediatric Umbilical Hernia Repair
The purpose of this study is to compare the use of ultrasound-guided bilateral rectus sheath blocks to local infiltration of anesthetic agent in the surgical wound in a pediatric population of patients undergoing umbilical hernia…
- Trial name
- NCT01015053
- Testing
- bilateral ultrasound-guided rectus sheath block, Wound infiltration
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Inguinal Hernia
Length of Hospital Stay in Laparoscopic Transabdominal Preperitoneal Vs. Open Mesh Repair in Inguinal Hernia: A Randomised Controlled Trial
To compare the mean length of hospital stay in laparoscopic trans abdominal preperitoneal repair versus open mesh repair in patients undergoing inguinal hernia repair with mesh.
- Trial name
- NCT05159232
- Testing
- hospital stay
- Where
- Pakistan
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Memon Medical Institute
Inguinal Hernia
Determine the Clinical Advantage of IV vs PO Acetaminophen
There is limited research on the clinical outcome differences between intravenous (IV) acetaminophen versus oral (PO) acetaminophen.
- Trial name
- NCT03558555
- Testing
- Acetaminophen IV Soln, Oral Acetaminophen, Saline
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Yan Lai
Ventral Hernia, Incisional Hernia
Antimicrobial Hernia Repair Device Clinical Study
This prospective clinical study will evaluate the safety and efficacy of the Cook® Antimicrobial Hernia Repair Device containing an antimicrobial to reinforce soft tissue during ventral or incisional hernia repair in…
- Trial name
- AMEX (NCT02401334)
- Testing
- Cook® Antimicrobial Hernia Repair Device
- Where
- 4 sites in Canada, United Kingdom
- Volunteers
- 24 people
- Sponsor
- Cook Group Incorporated
Inguinal Hernia
The Effect of Different Dose of Ketamine With Low Dose Rocuronium in Children
Rocuronium is suitable for rapid induction within 60-90 seconds and its effect last 24-40 minute after single bolus injection. For outpatient surgery with short operation time, low dose rocuronium is frequently used for rapid…
- Trial name
- NCT02646709
- Testing
- Rocuronium, ketamine 1, ketamine 1.5
- Volunteers
- 60 people
- Sponsor
- Ajou University School of Medicine
Hernia, Inguinal, Laparoscopic Surgery
Progrip Versus ProFlor: Two Fixation Free Devices for Laparoscopic Inguinal Hernia Repair
there are currently two methods for fixation free laparoscopic inguinal hernia repair specifically based on the intrinsic properties of the device used.
- Trial name
- ProPro (NCT06556498)
- Testing
- Proflor group, Progrip group
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Palermo
Ventral Hernia
Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM
The investigators aim to conduct a registry-based, randomized controlled trial to investigate if the robotic platform for minimally invasive ventral hernia repair with intraperitoneal onlay mesh (IPOM), when compared to the…
- Trial name
- NCT03283982
- Testing
- Robotic Ventral Hernia Repair with IPOM, Laparoscopic Ventral Hernia Repair with IPOM
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- The Cleveland Clinic