Clinical trials: Hernia, Abdominal
Ventral Hernia
Study Of Hernia Repair Utilizing The Bard Ventrio Hernia Patch
This study will collect data on patients undergoing hernia repair using the Bard Ventrio Hernia Patch. The study will evaluate hernia recurrence rates, operating time, quality of life and complications associated with the device…
- Trial name
- NCT00866814
- Testing
- Bard Ventrio Hernia Patch
- Where
- 7 sites in United States
- Volunteers
- 119 people
- Sponsor
- C. R. Bard
Congenital Diaphragmatic Hernia
Delayed Cord Clamping for Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a congenital anomaly associated with a high risk of mortality and need for life-saving interventions such as extracorporeal membrane oxygenation (ECMO), nitric oxide, and vasopressor…
- Trial name
- DING (NCT03314233)
- Testing
- DING
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital of Philadelphia
Intra-Abdominal Hypertension, Inguinal Hernia
Measuring Intraabdominal Pressure, Lactic Acid, and Urine Output
This study serves as a pilot study with the intention to to measure intraabdominal pressure, lactic acid, and urine output in obese individuals undergoing laparoscopic inguinal hernia repair.
- Trial name
- NCT05070572
- Testing
- Accuryn Monitoring System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Antonios Likourezos
Chronic Pain
Lichtenstein Patch or Prolene Hernia System (PHS) for Inguinal Hernia Repair
This randomised prospective study was designed to compare the convalescence and the long-term sequelae in inguinal hernia repair with either a bilayer mesh as devised by Gilbert (Prolene Hernia System®) or an onlay mesh applied…
- Trial name
- NCT01070693
- Testing
- Open mesh inguinal hernia repair, Prolene Hernia System, Lichtenstein technique
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Helsinki University Central Hospital
Inguinal Hernia
Determine the Clinical Advantage of IV vs PO Acetaminophen
There is limited research on the clinical outcome differences between intravenous (IV) acetaminophen versus oral (PO) acetaminophen.
- Trial name
- NCT03558555
- Testing
- Acetaminophen IV Soln, Oral Acetaminophen, Saline
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Yan Lai
Ventral Hernia
Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM
The investigators aim to conduct a registry-based, randomized controlled trial to investigate if the robotic platform for minimally invasive ventral hernia repair with intraperitoneal onlay mesh (IPOM), when compared to the…
- Trial name
- NCT03283982
- Testing
- Robotic Ventral Hernia Repair with IPOM, Laparoscopic Ventral Hernia Repair with IPOM
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- The Cleveland Clinic
Ventral Hernia
Hernia Repair in Multiply Morbid Patients
Support of a ventral hernia repair with a prosthetic mesh has been demonstrated to result in a diminished rate of hernia recurrence.
- Trial name
- RAM2P (NCT00930787)
- Testing
- Strattice Reconstructive Tissue Matrix (Hernia Repair), Proceed Surgical Mesh (Hernia repair)
- Where
- 13 sites in United States
- Volunteers
- 23 people
- Sponsor
- LifeCell
Hernia, Hernia, Ventral
T-GENVIH-003 LTFU (Long Term Follow Up) Study
The T-GENVIH-003 study will collect additional, longer term performance data of Gentrix® Surgical Matrix used for reinforcement of ventral hernia repairs from a subset population (i.e., the twenty-one minimally invasive surgical…
- Conditions
- Hernia, Hernia, Ventral, Pathological Conditions, Anatomical, Hernia, Abdominal
- Trial name
- NCT06034652
- Testing
- Integra® Gentrix® Surgical Matrix
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Integra LifeSciences Corporation
Inguinal Hernia
Effect of Suture for Mesh Fixation in Lichtenstein Hernia Repair
The investigators want to evaluate the effect of suturing the mesh versus using a self-adhesive mesh for Lichtenstein hernia repair. Effect parameters include chronic pain.
- Trial name
- Dangrip (NCT00815698)
- Testing
- suture, no suture
- Where
- 5 sites in Denmark
- Volunteers
- 334 people
- Sponsor
- Jacob Rosenberg
Hernia, Inguinal
Tacking Mesh Versus Self-fixating Mesh for Inguinal Hernia Repair
Investigators are testing whether tacking mesh or self-fixating mesh used for inguinal hernia repair makes any difference in short-term pain or return to normal activities following the operation.
- Trial name
- NCT03247985
- Testing
- PROLENE Polypropylene Tacking Mesh, ProGrip Self-fixating Mesh
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Mayo Clinic
Ventral Hernia
Gastrointestinal Tract Recovery in Patients Undergoing Open Ventral Hernia Repair
The purpose of this study is to determine whether Alvimopan (Entereg) in ventral hernia surgery patients is associated with accelerated gastrointestinal recovery and reduced length of hospital stay compared to placebo controls.
- Trial name
- NCT02379858
- Testing
- Alvimopan
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medical College of Wisconsin
Recurrent Hernia
Review of Complex Recurrent Hernia Repair
Abdominal wall incisional hernia is a common finding in patients who have undergone previous intra-abdominal surgeries. Common methods of abdominal fascial closure include primary closure, mesh inlay versus onlay, with or without…
- Trial name
- BARS (NCT01644695)
- Testing
- Bony Anchoring Reinforcement System
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Institute For Advanced Reconstruction
Inguinal Hernia
Urinary Retention After Laparoscopic Inguinal Hernia Repair: Comparing the Use of the Intraoperative Urinary Catheter
This will be a randomized controlled study which will compare the rate of post-operative urinary retention after laparoscopic inguinal hernia repair between patients who receive an intra-operative urinary catheter and those who…
- Trial name
- NCT03835351
- Testing
- Urinary Catheter
- Where
- United States
- Volunteers
- 491 people
- Sponsor
- The Cleveland Clinic
Hernia, Inguinal
Validation of a Subjective Rating Scale for Assessment of the Surgical Workspace in Laparoscopy
It is of great importance to obtain optimal surgical conditions for the surgeon in order to increase patient safety. The effect of different interventions on surgical conditions has been assessed by various surgeon-assessed…
- Trial name
- NCT02545270
- Testing
- Level of pneumoperitoneum 12-9-6 mmHg, Level of pneumoperitoneum 11-8-5 mmHg, Level of pneumoperitoneum 10-7-4 mmHg
- Where
- 2 sites in Denmark
- Volunteers
- 16 people
- Sponsor
- Herlev Hospital
Inguinal Hernia
Neo-nervegenesis in Inguinal Hernia Implant ProFlor
The investigation is aimed at specifically demonstrating the ingrowth of newly formed nervous elements within a 3D dynamic responsive implant for inguinal hernia repair.
- Trial name
- NCT04171102
- Testing
- ProFlor Hernia implant
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Ventral Hernia, Incisional Hernia
A Prospective, Multi-Center Study of Phasix™ Mesh for Ventral or Incisional Hernia Repair.
Single-arm study of Phasix Mesh in High Risk patients looking at SSI and recurrence rates.
- Trial name
- NCT01961687
- Testing
- Resorbable Mesh
- Where
- 16 sites in United States
- Volunteers
- 121 people
- Sponsor
- C. R. Bard
Hernia Repair With Compartment Syndrome
Feasibility Study of The Use of FLEX HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrix in The Closure of Abdominal Wall Defects With Component Separation in Clean or Contaminated Cases
This study examines the feasibility of using Flex HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrixin the repair of hernias.
- Trial name
- Flex HD (NCT01597128)
- Testing
- Flex HD, Strattice
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- John Roth
Inguinal Hernia
Study Evaluating the Impact of Mesh Pore Size on Chronic Pain After Lichtenstein Hernioplasty
The aim of the present study is to determine whether usage of mesh with larger pores, compared with mesh with smaller pores, would result in decreased rate of chronic pain after open inguinal hernia repair.
- Trial name
- NCT02500056
- Testing
- Optilene LP mesh, Ultrapro mesh
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Tartu University Hospital
Inguinal Hernia
Awake Caudal Catheter vs General Anesthesia
It is well established that preterm inguinal hernias discovered in the NICU pose a significant surgical risk due to the associated co-morbid conditions that accompany these patients.
- Trial name
- NCT05919732
- Testing
- Bupivacaine, Dexmedetomidine, Caffeine, Tylenol, Propofol, rocuronium, caffeine, Tylenol, bupivacaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Analgesia
Study of Post-Herniorrhaphy Non-opioid MMA Regimens
This is a Phase 3b, open-label study to assess postoperative opioid use in subjects undergoing unilateral open inguinal herniorrhaphy with intraoperative administration of HTX-011 and a postoperative non-opioid multimodal…
- Trial name
- NCT03907176
- Testing
- HTX-011, Luer lock applicator, Ibuprofen
- Where
- 30 sites in United States
- Volunteers
- 209 people
- Sponsor
- Heron Therapeutics