Clinical trials: Hernia, Inguinal/Surgery
Inguinal Hernia
Plasma Total Antioxidant Status and Thiobarbituric Acid-reacting Substances in Patients With Inguinal Hernia
Introduction: Any form of trauma, including surgery is known to result in oxidative stress. Single incision laparoscopy is a step forward towards almost scarless surgery.
- Trial name
- NCT02336256
- Testing
- Procedures of hernia repair.
- Volunteers
- 34 people
- Sponsor
- Poznan University of Medical Sciences
Inguinal Hernia
An Efficiency/Safety Study of Surgical Tissue Glue to Treat Inguinal Hernias
Prospective, multicenter, observational registry to collect data of laparoscopic inguinal hernia repair using surgical tissue glue fixation. The objective is to determine the prevalence of chronic pain at 1 year.
- Trial name
- NCT01669837
- Testing
- Mesh fixation with surgical tissue glue
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- Duomed
Inguinal Hernia, Chronic Pain
A National Center for Persistent Severe Pain After Groin Hernia Repair
This prospective, consecutive cohort study presents nationwide 5-year outcome data on patients with severe persistent pain after groin hernia repair (SPG).
- Trial name
- Q5Y (NCT03713047)
- Volunteers
- 222 people
- Sponsor
- University of Copenhagen
Inguinal Hernia
Clinical Trial to Compare TAPP (Transabdominal Preperitoneal) vs TEP (Totally Extraperitoneal) y Approach for Women's Inguinal Hernia on an Outpatient Basis
Open prospective randomised clinical trial enrolling women who suffer from inguinal or femoral hernia, to evaluate if TEP approach is superior to TAPP concerning postoperative development, principally postoperative pain, with no…
- Trial name
- WOLAP (NCT04114344)
- Testing
- TAPP, TEP
- Where
- Spain
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Inguinal Hernia
Task Sharing in InGuinal hErnia Repair Between Surgeons and Non-surgeon Physicians
TIGER is a multicentre, 2-arm, parallel group, assessor blinded, non-inferiority randomised controlled trial with an internal pilot to assess if non-surgeon physicians (NSPs) can effectively perform mesh inguinal hernia repair…
- Trial name
- TIGER (NCT06165133)
- Testing
- Mesh inguinal hernia repair performed by Non-Surgeon Physicians (NSP), Mesh inguinal hernia repair performed by fully trained surgeons
- Volunteers
- 1,782 people
- Sponsor
- University of Birmingham
Opioid Use, Inguinal Hernia
Preventing Opioid Misuse Through Safe Opioid Use Agreements Between Patients and Surgical Providers
The effect of pain agreements to reduce opioid misuse is an accepted practice in many settings, but it has never been applied to the acute care setting.
- Conditions
- Opioid Use, Inguinal Hernia, Ventral Hernia
- Trial name
- NCT06167759
- Testing
- Opioid Use Agreement
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- The University of Texas Health Science Center, Houston
Inguinal Hernia
Neuroinflammatory and Neurocognitive Effects of Spinal vs. Inhalational Anesthesia for Elective Surgery in Infants
Significant concern regarding the safety of general anesthesia in children has arisen due to myriad animal studies suggesting neurotoxicity of commonly used anesthetic agents.
- Trial name
- NCT02521831
- Testing
- Spinal Anesthesia (bupivacaine), General Anesthesia (isoflurane)
- Sponsor
- Emmett Whitaker, M.D.
Hernia, Inguinal
Validation of a Subjective Rating Scale for Assessment of the Surgical Workspace in Laparoscopy
It is of great importance to obtain optimal surgical conditions for the surgeon in order to increase patient safety. The effect of different interventions on surgical conditions has been assessed by various surgeon-assessed…
- Trial name
- NCT02545270
- Testing
- Level of pneumoperitoneum 12-9-6 mmHg, Level of pneumoperitoneum 11-8-5 mmHg, Level of pneumoperitoneum 10-7-4 mmHg
- Where
- 2 sites in Denmark
- Volunteers
- 16 people
- Sponsor
- Herlev Hospital
Anterior Ilıac Block, Hernia Surgery
Effect of Anterior Iliac Block on Postoperative Analgesia and Patient Satisfaction in Inguinal Hernia Repair Surgery
Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide and presents challenges in anesthesia selection and postoperative pain management.
- Conditions
- Anterior Ilıac Block, Hernia Surgery, Spinal Anesthesia
- Trial name
- NCT07533383
- Testing
- Anterior Iliac Block, Control Group (A):
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Pain, Postoperative, Regional Anesthesia
Transversalis Fascia Plane Block in Pediatric Patients
to investigate the effects of Transversalis Fascia Plan Block after induction of anesthesia on perioperative opioid consumption, hemodynamic changes, postoperative FLACC pediatric pain score, non-opioid analgesic use and parental…
- Conditions
- Pain, Postoperative, Regional Anesthesia, Parental Satisfaction
- Trial name
- NCT06391528
- Testing
- Transversalis Fascia Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Inguinal Hernia
Clinical Performance of HISTOACRYL® LAPFIX - CANNULA for Laparoscopic Inguinal Hernia Repair
The goal of this retrospective study is to identify the incidence of hernia recurrence following the application of Histoacryl® Lapfix - Cannula for laparoscopic mesh fixation in patients undergoing hernia repair surgery.
- Trial name
- HISTOLAP (NCT06298500)
- Testing
- hernia repair surgery
- Where
- Spain
- Volunteers
- 443 people
- Sponsor
- Aesculap AG
Hernia, Inguinal, Surgical Mesh
Mesh and Mesh Fixation in Laparoscopic Groin Hernia Surgery
The study attempts to quantify the relative risks for recurrence depending on complex combinations of plausible risk factors, in particular mesh, mesh fixation, hernia size and hernia type.
- Conditions
- Hernia, Inguinal, Surgical Mesh, Laparoscopy, Hernia
- Trial name
- NCT03755219
- Testing
- TEP, TAPP
- Volunteers
- 38,450 people
- Sponsor
- Bengt Novik
Anesthesia
Ultrasound Guided TAP Block Versus Caudal Block in Pediatrics
The use of pediatric regional anesthesia has increased because of its effective pain control, improved safety profile of local anesthetic agents, in addition to the introduction of ultra-sound.
- Trial name
- NCT03701126
- Testing
- Transversus Abdominis Plane Block, Caudal Block, Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Zagazig University
Postoperative Pain, Inguinal Hernia Unilateral
The Comparison of the Transversalis Fascia Plane Block With Ilioinguinal/Iliohypogastric Nerve Block
This study compares the transversalis fascia plane block with the ilioinguinal/iliohypogastric nerve block in children undergoing hernia repair surgery.
- Conditions
- Postoperative Pain, Inguinal Hernia Unilateral, Children, Only
- Trial name
- NCT03520907
- Testing
- Transversalis Fascia Plane Block, Ilioinguinal/iliohypogastric Nerve Block
- Where
- Japan
- Volunteers
- 80 people
- Sponsor
- Kazuhiko Okuyama, MD
Inguinal Hernia, Surgery--Complications
Bassini Inguinal Hernia Repair: Obsolete Or Still A Viable Surgical Option?
Retrospective review of hernia surgery patients at HHMcGuire VAMC focusing on repair type and postoperative complications.
- Conditions
- Inguinal Hernia, Surgery--Complications, Surgical Complication
- Trial name
- NCT04888078
- Testing
- Bassini hernia repair
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Postoperative Pain
Caudal Block v/s Local Wound Infiltration for Pain Control in Pediatric Patients After Operation for Inguinal Hernia
This randomized controlled trial aims to compare the analgesic efficacy of local wound infiltration with Ropivacaine versus Caudal Block with Ropivacaine in pediatric patients undergoing surgery for inguinal hernia
- Trial name
- NCT07747038
- Testing
- Caudal Block with Ropivacaine Intervention, Local Wound Infiltration with Ropivacaine Intervention, Intravenous Paracetamol Suspension Intervention
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Fatima Memorial Hospital
Inguinal Surgery
Ibuprofen Compared to Morphine as a Pediatric Postoperative Pain Management Tool Following Inguinal Surgery
Morphine is now the most commonly used opioid in children for pain management even though the safety of morphine use in children is a primary concern for parents as it is perceived to have more associated risks.
- Trial name
- NCT02603848
- Testing
- Ibuprofen, Morphine
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Inguinal Hernia
Activity Restrictions After Inguinal Hernia Repair
This research is intended to be a pilot study to identify differences in outcomes for varied lifting and physical activity precautions following surgical repair of single-sided inguinal hernias.
- Trial name
- NCT05867134
- Testing
- Removal of postoperative lifting restrictions
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Hernia
Does Tension-Free Herniorrhaphy or Laparoscopic Herniorrhaphy Achieve Equal or Better Recurrence Rates and Lower Costs While Achieving Equivalent Outcomes for Hernia Patients?
Inguinal hernia is one of the most common worldwide afflictions of men. The presence of an inguinal hernia is indication for its repair. Approximately 700,000 hernia repairs are performed in the U.S.
- Trial name
- NCT00032448
- Testing
- Standardized tension-free herniorrhaphy with prosthesis
- Where
- 14 sites in United States
- Volunteers
- 2,200 people
- Sponsor
- US Department of Veterans Affairs
İnguinal Hernia, Complication,Postoperative
Post-Surgical Outcomes of Conventional vs 3-Point Mesh Fixation in Lichtenstein Repair: An RCT
This is a single-center, parallel-group randomized controlled trial conducted in 2025-2025 at the General Surgery Ward of the Sindh Institute of Urology and Transplantation (SIUT), Karachi.
- Conditions
- İnguinal Hernia, Complication,Postoperative, Pain, Postoperative
- Trial name
- COMET (NCT07334548)
- Testing
- 3-point mesh fixation, Conventional Mesh Fixation
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Sahar Mughis