Clinical trials: Hernia, Ventral
Hernia, Ventral Hernia
Prospective Clinical Evaluation of High-Purity Type I Collagen in Select High-Risk Hernia Repair Scenarios
This prospective, single-arm clinical study evaluates the safety, feasibility, and early clinical outcomes of High-Purity Type I Collagen (HPTC; Surgicoll-Mesh®) when used as a biologic reinforcement in selected hernia repair…
- Conditions
- Hernia, Ventral Hernia, Incisional Hernia, İnguinal Hernia
- Trial name
- NCT07360691
- Testing
- High-Purity Type I Collagen Mesh
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Incisional Hernia Repair, Ventral Hernia Repair
Comparative Evaluation of Preoperative Preparation Methods in Patients With Large Incisional Hernias
Patients with large, complex, or giant incisional hernias often require advanced preoperative optimization to facilitate safe abdominal wall reconstruction and reduce postoperative complications.
- Trial name
- AWR-PREP (NCT07549113)
- Testing
- Botulinum Toxin A (Botox ), Progressive Preoperative Pneumoperitoneum, Combined Preoperative Preparation
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital
Ventral Hernia Repair
Cost-Effectiveness of Retromuscular Hernia Repair
This prospective observational study aims to evaluate the clinical outcomes and cost-effectiveness of retromuscular midline ventral hernia repair using open, laparoscopic and robotic approaches.
- Trial name
- ECOHERNIA-3 (NCT07530159)
- Testing
- Retromuscular ventral hernia repair, Polypropylene mesh, Standard perioperative care
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fátima Hinojosa Ramírez
Ventral Hernia
Outpatient Repair of Small Reducible Ventral Hernias Using Local Anesthesia: A Pilot Study
Primary midline hernias, including umbilical and epigastric hernias, are prevalent surgical conditions, necessitating intervention.
- Trial name
- OPD-repair (NCT07514273)
- Testing
- Repair of small ventral hernia under lokal anesthesia, Hernia Repair, OPD Repair
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Region Örebro County
Ventral Hernia
Post-market Study of the Biodesign Hernia Graft
The purpose of this study is to collect data on the performance of the Biodesign® Hernia Graft when used to reinforce soft tissues during ventral hernia repair.
- Trial name
- NCT04294446
- Testing
- Biodesign Hernia Graft
- Where
- 3 sites in United States, Canada
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cook Biotech Incorporated
Ventral Hernias, Cytoreductive Surgery
Ventral Hernias Following Cytoreductive Surgery : Incidence, Risk Factors and Surgical Management.
Cytoreductive surgery (CRS), with or without hyperthermic intraperitoneal chemotherapy (HIPEC), is currently the standard treatment for advanced peritoneal tumors, including pseudomyxoma peritonei (PMP), colorectal, and ovarian…
- Trial name
- NCT07451483
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Incisional Ventral Hernia
Cytokine Response to Abdominal Wall Reconstruction
This is a prospective, observational translational study of patients undergoing major abdominal wall reconstruction with primary fascial closure.
- Trial name
- NCT07422584
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hernia, Ventral Hernia Repair
Complication Rate of Onlay vs Sublay Mesh Repair in Incisional Hernia
This randomized controlled trial was conducted at the Department of Surgery, Hayatabad Medical Complex, Peshawar. Eligible patients with incisional hernia were randomized into two parallel groups: sublay mesh repair and onlay…
- Conditions
- Hernia, Ventral Hernia Repair, Incisional Hernia Repair, Abdominal Wall Hernia
- Trial name
- NCT07401446
- Testing
- Sublay Mesh Repair, Onlay Mesh Repair
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Umbilical Hernia Repair, Epigastric Hernia Repair
Outpatient Department Repair of Small Primary Ventral Hernias
Ventral hernias are among the most common conditions requiring surgical intervention. Due to their benign nature, elective repairs of primary ventral hernias are usually given low priority for planned surgery.
- Conditions
- Umbilical Hernia Repair, Epigastric Hernia Repair, Primary Ventral and Incisional Hernia Repair
- Trial name
- OPD-R (NCT07351760)
- Testing
- Outpatient department repair
- Where
- Sweden
- Volunteers
- 37 people
- Sponsor
- Karolinska Institutet
Ventral Hernia Repair
Robotic Minimally Invasive Ventral Hernia Repair With DEXTER
The aim of this clinical investigation is to confirm the perioperative and early postoperative safety and clinical performance (efficacy) of the Dexter Robotic System, in patients undergoing incisional or primary ventral hernia…
- Trial name
- RAVEN (NCT07071740)
- Testing
- ventral hernia repair
- Where
- 5 sites in Austria, France and 2 more
- Volunteers
- 33 people
- Sponsor
- Distalmotion SA
Hernia, Ventral, Hernia Incisional
Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application
The SYN 20-01 Study is a non-interventional, prospective, multicenter, multicohort, international, post-market clinical investigation looking into the assessment of GORE® SYNECOR Biomaterial in focused patient populations and in…
- Conditions
- Hernia, Ventral, Hernia Incisional, Hernia Incisional Ventral
- Trial name
- SYN 20-01 (NCT05094089)
- Testing
- Hernia repair with mesh
- Where
- 15 sites in United States, Italy and 2 more
- Volunteers
- 320 people
- Sponsor
- W.L.Gore & Associates
Hernia, Hernia, Ventral
Preoptimisation in Ventral Hernia Surgery
The study is a multicentre, single-blinded, randomised controlled trial. Ventral hernia patients with an aperture width between four and eight centimetres are randomised to either participation in a multimodal preoptimisation…
- Conditions
- Hernia, Hernia, Ventral, Hernia Incisional, Hernia, Umbilical
- Trial name
- PreOpt (NCT07316426)
- Testing
- preoptimisation programme
- Where
- 5 sites in Sweden
- Volunteers
- 130 people
- Sponsor
- Umeå University
Emergency Inguinal Hernia Repair, Emergency Ventral Hernia Repair
Emergency Hernia Repair
Emergency hernia repairs are associated with significantly higher morbidity and mortality compared with elective hernia surgery.
- Trial name
- NCT07314398
- Testing
- Emergency hernia repair
- Volunteers
- 600 people
- Sponsor
- Oulu University Hospital
Ventral Hernia
Biological Meshes in Infected Fields: a Randomized Controlled Trial
The SIMBIOSE trial is a large multicenter phase III prospective randomized controlled single blinded trial comparing the use of biological mesh versus traditional wound care without biological mesh in patients with an infected…
- Trial name
- SIMBIOSE (NCT01594450)
- Testing
- Biological mesh, without biological mesh
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Lille
Ventral Hernia
Surgical Approaches for Medium-to-Large Ventral Hernias: Open, Laparoscopic, and Robotic-Assisted Techniques
The purpose of this project is to investigate whether the use of the new robot-assisted technique in surgery for large and medium-sized ventral midline hernias has brought tangible benefits to patients in terms of Textbook…
- Trial name
- NCT07275346
- Where
- Sweden
- Volunteers
- 750 people
- Sponsor
- Andreas Älgå
Hernia, Ventral, Ileus
The Impact of Sugammadex on Ileus After Abdominal Wall Reconstruction
The aim of the study is to determine if the usage of sugammadex would reduce the time to return of bowel function when compared to standard of care (neostigmine/glycopyrrolate) when used for neuromuscular blockade reversal in…
- Trial name
- NCT05985343
- Testing
- Neostigmine / Glycopyrrolate, Sugammadex
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Clayton Petro
Obesity, Ventral Hernia
Does a Virtual Coach Offer a Better Solution for Weight Reduction in Ventral Hernia Patients With Obesity?
The purpose for this research is to create a MyChart-enabled virtual coach that assists obese patients lose weight prior to ventral hernia surgery.
- Trial name
- NCT05797974
- Testing
- MyChart enabled virtual weight loss coach, Standard preoperative weight loss tools
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Florida
Ventral Hernia
Video-based Collaborative Learning to Improve Ventral Hernia Repair
Recent studies demonstrate the critical role of individual surgeon performance, including both the approach they take to an operation as well as their technical skill, in determining patient outcomes.
- Trial name
- NCT04173884
- Testing
- Coaching, Constructive Feedback
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ventral Hernia
A Comparison of the Outcomes in Fortiva and Strattice Mesh
A comparison of ventral hernia repair with Strattice and Fortiva mesh.Primary The study team aims to determine the hernia recurrence rates for RTI Surgical biologic mesh (Fortiva) compared to Strattice.
- Trial name
- NCT05572021
- Testing
- Prospective Ventral Hernia Repair with Fortiva, RetroSpective Ventral Hernia Repair with Strattice
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Wake Forest University Health Sciences
Inguinal Hernia, Ventral Hernia
Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs
While studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is…
- Trial name
- NCT05177991
- Testing
- Liposomal Bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Leslie Son