Clinical trials: Hernia, Ventral
Ventral Hernia
Outpatient Repair of Small Reducible Ventral Hernias Using Local Anesthesia: A Pilot Study
Primary midline hernias, including umbilical and epigastric hernias, are prevalent surgical conditions, necessitating intervention.
- Trial name
- OPD-repair (NCT07514273)
- Testing
- Repair of small ventral hernia under lokal anesthesia, Hernia Repair, OPD Repair
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Region Örebro County
Incisional Hernia
Xen Matrix™ AB Surgical Graft in Ventral or Incisional Midline Hernias
This study aims to prospectively explore the use of XenMatrix™ AB Surgical Graft for ventral or incisional midline hernia repair in patients across all wound classes ("All Comers") through 24 months post repair.
- Trial name
- NCT02691962
- Testing
- Xen Matrix AB
- Where
- 11 sites in United States
- Volunteers
- 75 people
- Sponsor
- C. R. Bard
Ventral Hernia
Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM
The investigators aim to conduct a registry-based, randomized controlled trial to investigate if the robotic platform for minimally invasive ventral hernia repair with intraperitoneal onlay mesh (IPOM), when compared to the…
- Trial name
- NCT03283982
- Testing
- Robotic Ventral Hernia Repair with IPOM, Laparoscopic Ventral Hernia Repair with IPOM
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- The Cleveland Clinic
Hernia Surgery, Umbilical Hernia Repair
The PAPYRUS Study: Permanent vs. Absorbable Sutures in PrimarY Repair of Umbilical HerniaS: A Multicentre, Single-blind, Non-inferiority, Randomized Controlled Trial
Umbilical hernias can be found in over a quarter of the population and comprise of 15% of hernia repairs performed in Canada. While mesh repair is commonly used for larger hernias, smaller hernia defects are often closed with…
- Trial name
- PAPYRUS (NCT07156188)
- Testing
- Permanent Suture, Absorbable
- Where
- 5 sites in Canada
- Volunteers
- 914 people
- Sponsor
- University of British Columbia
Ventral Hernia
AFFIX: Post-market Study of MaxTack™ Motorized Fixation Device in Subjects Undergoing Ventral Hernia Repair
Medtronic is sponsoring and funding the AFFIX study, a prospective, post-market, multicenter, nonrandomized, single-arm, interventional clinical study.
- Trial name
- AFFIX (NCT06710795)
- Testing
- MaxTack™ Motorized Fixation Device
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- Medtronic - MITG
Ventral Hernia
Onlay and Sublay Mesh in Treatment of Ventral Hernia
Hernia is defined as aprotrusion of viscus or part of viscus usually within a peritonial sac through a defect in the abdominal wall.
- Trial name
- NCT06867029
- Testing
- Onlay Mesh
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Rectocele, Enterocele
A Study Evaluating the Clinical Outcome of a Modified d'Hoore Technique for Laparoscopic Ventral Mesh Rectopexy
The purpose of this observational study is to evaluate the clinical outcome of a modified d'Hoore technique for laparoscopic ventral mesh rectopexy in patients with primary rectal prolapse, rectocele and/or enterocele.The goal of…
- Conditions
- Rectocele, Enterocele, Rectal Prolapse
- Trial name
- POP-01 (NCT04564677)
- Testing
- Ifabond (Péters surgical)
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Duomed
Ventral Hernia Repair
Reducing INfection at the Surgical SitE With Antibiotic Irrigation During Ventral Hernia Repair (RINSE Trial)
This is a study to determine if the incidence of infection at the Surgical SitE is impacted if with Antibiotic Irrigation is used during Ventral Hernia Repair (RINSE Trial)
- Trial name
- RINSE (NCT03945357)
- Testing
- Gemcitabine/ clindamycin, Normal saline
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Prisma Health-Upstate
Ileus
A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair
This study will evaluate the safety and efficacy of two different dose regimens (12 milligrams [mg] and 24 mg) of IV MOA-728 versus placebo in shortening the time to return of bowel function in participants receiving opioid…
- Trial name
- NCT00528970
- Testing
- MOA-728
- Where
- 106 sites in United States, Australia and 9 more
- Volunteers
- 374 people
- Sponsor
- Bausch Health Americas, Inc.
Ventral Hernia Repair
ORION Study: Mesh Position and Risk During Subsequent Minimally Invasive Abdominal Surgery
Ventral hernia repair is one of the most commonly performed abdominal surgical procedures worldwide, increasingly carried out using minimally invasive techniques.
- Trial name
- ORION (NCT07384962)
- Where
- Italy
- Volunteers
- 790 people
- Sponsor
- Istituto Auxologico Italiano
Ventral Hernia
Reoperation Rate Versus Clinical Recurrence After Ventral Hernia Repair
The risk for recurrence after ventral hernia repair is often based on reoperation rates with short follow-up rather than recurrences identified by clinical examinations.
- Trial name
- NCT01325246
- Where
- Denmark
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Ventral Hernia, Pain
Transfacial Sutures Versus Stapler for Mesh Fixation in Laparoscopic Ventral Hernia Repair
Hernia of the abdominal wall occur frequently after various surgical procedures of the abdomen and are increasingly performed by laparoscopic means.
- Trial name
- NCT00773851
- Testing
- mesh fixation by transfacial sutures, mesh fixation by staples
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- Medtronic - MITG
Ventral Hernia, Surgery
STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair
The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes.
- Conditions
- Ventral Hernia, Surgery, Risk Reduction, Lifestyle
- Trial name
- STRONG-Hernia (NCT06611462)
- Testing
- Prehabilitation (the STRONG programme)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Bispebjerg Hospital
Ventral Hernias, Cytoreductive Surgery
Ventral Hernias Following Cytoreductive Surgery : Incidence, Risk Factors and Surgical Management.
Cytoreductive surgery (CRS), with or without hyperthermic intraperitoneal chemotherapy (HIPEC), is currently the standard treatment for advanced peritoneal tumors, including pseudomyxoma peritonei (PMP), colorectal, and ovarian…
- Trial name
- NCT07451483
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Hernia
AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE
The primary purpose of this clinical trial is to assess the safety and performance of the ECLIPSIUM device in securing mesh during ventral hernia repair.
- Trial name
- UNITE (NCT07277946)
- Testing
- ECLIPSIUM® System, Resorbable tacks (AbsorbaTack/SorbaFix)
- Where
- 12 sites in United States
- Volunteers
- 240 people
- Sponsor
- Tissium
Hernia, Ventral
A Prospective Case Series Evaluating Surgimend Mp® In Patients Undergoing Complex Abdominal Hernia Repair
Large abdominal wall hernias are surgically challenging to repair and often associated with significant postoperative complications.
- Trial name
- NCT03450473
- Testing
- SurgiMend® MP
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Washington University School of Medicine
Ventral Hernia
A Prospective Evaluation of Pain After Non-complex Ventral Hernia Repair
The study aims to evaluate outcomes relating to pain and QOL after robotic-assisted or laparoscopic non-complex ventral hernia repair.
- Trial name
- ASPIRE (NCT04855227)
- Testing
- robotic-assisted ventral hernia repair
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Intuitive Surgical
Ventral Hernia
Long Term Complaints After Elective Repair for Small Umbilical or Epigastric Hernias
The purpose of this study is to compare the long-term complaints after ventral hernia repair after insertion of different types of mesh compared with primary suture. Also recurrence of hernia will be discussed.
- Trial name
- NCT01501682
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Zealand University Hospital
Ventral Hernia
Risk Factors and Results of Emergency Ventral Hernia Repair
The aim of present study was to evaluate the clinical course after emergency ventral hernia repair in terms of 30-day-readmission, -reoperation and -mortality and to identify risk factors for emergency repair.
- Trial name
- NCT01589276
- Where
- Denmark
- Volunteers
- 10,976 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Ventral Incisional Hernia
SUTURE TYPE AND RECURRENCE RISK AFTER INCISIONAL HERNIA REPAIR
Incisional hernia is a common condition after abdominal surgery and is often associated with pain, impaired physical function, and reduced quality of life.
- Trial name
- TAFAR (NCT07891091)
- Testing
- Suturing of hernia defect with non-absorbable suture, Suturing of hernia defect with slowly absorbable suture
- Where
- Sweden
- Volunteers
- 980 people
- Sponsor
- Ersta Diakoni